GLENN JAFFE

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc Macular Morphology and Visual Acuity in the Comparison of Age-related Macular Degeneration Treatments Trials
    Glenn J Jaffe
    Department of Ophthalmology, Duke University, Durham, North Carolina Electronic address
    Ophthalmology 120:1860-70. 2013
  2. doi request reprint Reimplantation of a fluocinolone acetonide sustained drug delivery implant for chronic uveitis
    Glenn J Jaffe
    Duke Eye Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    Am J Ophthalmol 145:667-675. 2008
  3. ncbi request reprint Uveitis in the elderly: epidemiological data from the National Long-term Care Survey Medicare Cohort
    Sherman W Reeves
    Duke University Eye Center, Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina 27710, USA
    Ophthalmology 113:307.e1. 2006
  4. ncbi request reprint Management of condensation on a foldable acrylic intraocular lens after vitrectomy and fluid-air exchange
    G J Jaffe
    Department of Ophthalmology, Duke University, Durham, NC 27710, USA
    Am J Ophthalmol 124:692-3. 1997
  5. ncbi request reprint Long-term follow-up results of a pilot trial of a fluocinolone acetonide implant to treat posterior uveitis
    Glenn J Jaffe
    Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina, USA
    Ophthalmology 112:1192-8. 2005
  6. ncbi request reprint Optical coherence tomography to detect and manage retinal disease and glaucoma
    Glenn J Jaffe
    Duke Eye Center, Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Am J Ophthalmol 137:156-69. 2004
  7. ncbi request reprint Safety and pharmacokinetics of an intraocular fluocinolone acetonide sustained delivery device
    G J Jaffe
    Department of Ophthalmology, Duke University, Durham, North Carolina Control Delivery Systems, Watertown, Massachusetts, USA
    Invest Ophthalmol Vis Sci 41:3569-75. 2000
  8. ncbi request reprint Fluocinolone acetonide sustained drug delivery device to treat severe uveitis
    G J Jaffe
    Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina, USA
    Ophthalmology 107:2024-33. 2000
  9. doi request reprint Combined fluocinolone acetonide intravitreal insertion and glaucoma drainage device placement for chronic uveitis and glaucoma
    Paula E Malone
    Department of Ophthalmology, Duke University Medical Center, Durham, NC 27710, USA
    Am J Ophthalmol 149:800-6.e1. 2010
  10. ncbi request reprint Fluocinolone acetonide implant (Retisert) for noninfectious posterior uveitis: thirty-four-week results of a multicenter randomized clinical study
    Glenn J Jaffe
    Duke University Eye Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ophthalmology 113:1020-7. 2006

Collaborators

Detail Information

Publications34

  1. pmc Macular Morphology and Visual Acuity in the Comparison of Age-related Macular Degeneration Treatments Trials
    Glenn J Jaffe
    Department of Ophthalmology, Duke University, Durham, North Carolina Electronic address
    Ophthalmology 120:1860-70. 2013
    ..To describe the effects of treatment for 1 year with ranibizumab or bevacizumab on macular morphology and the association of macular morphology with visual acuity (VA) in eyes with neovascular age-related macular degeneration (AMD)...
  2. doi request reprint Reimplantation of a fluocinolone acetonide sustained drug delivery implant for chronic uveitis
    Glenn J Jaffe
    Duke Eye Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    Am J Ophthalmol 145:667-675. 2008
    ..To determine the effects of a second fluocinolone implant inserted in eyes with uveitis in which recurrent inflammation developed after the original implant was placed...
  3. ncbi request reprint Uveitis in the elderly: epidemiological data from the National Long-term Care Survey Medicare Cohort
    Sherman W Reeves
    Duke University Eye Center, Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina 27710, USA
    Ophthalmology 113:307.e1. 2006
    ..In this analysis, we use Medicare claims data to define the population-based incidence and prevalence of uveitis in the United States elderly population...
  4. ncbi request reprint Management of condensation on a foldable acrylic intraocular lens after vitrectomy and fluid-air exchange
    G J Jaffe
    Department of Ophthalmology, Duke University, Durham, NC 27710, USA
    Am J Ophthalmol 124:692-3. 1997
    ..To describe the management of condensation on the posterior surface of a foldable acrylic intraocular lens during vitrectomy and fluid-air exchange...
  5. ncbi request reprint Long-term follow-up results of a pilot trial of a fluocinolone acetonide implant to treat posterior uveitis
    Glenn J Jaffe
    Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina, USA
    Ophthalmology 112:1192-8. 2005
    ..To investigate the safety and efficacy of a fluocinolone acetonide intravitreal implant in the treatment of noninfectious posterior uveitis...
  6. ncbi request reprint Optical coherence tomography to detect and manage retinal disease and glaucoma
    Glenn J Jaffe
    Duke Eye Center, Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Am J Ophthalmol 137:156-69. 2004
    ..To review basic principles of optical coherence tomography, and to describe its use in the diagnosis and management of retinal diseases and glaucoma...
  7. ncbi request reprint Safety and pharmacokinetics of an intraocular fluocinolone acetonide sustained delivery device
    G J Jaffe
    Department of Ophthalmology, Duke University, Durham, North Carolina Control Delivery Systems, Watertown, Massachusetts, USA
    Invest Ophthalmol Vis Sci 41:3569-75. 2000
    ..To determine the safety and pharmacokinetics of an intraocular fluocinolone acetonide sustained drug delivery device...
  8. ncbi request reprint Fluocinolone acetonide sustained drug delivery device to treat severe uveitis
    G J Jaffe
    Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina, USA
    Ophthalmology 107:2024-33. 2000
    ..In this report, we describe a pilot safety and efficacy trial of a novel sustained drug delivery system containing fluocinolone acetonide to treat patients with severe uveitis...
  9. doi request reprint Combined fluocinolone acetonide intravitreal insertion and glaucoma drainage device placement for chronic uveitis and glaucoma
    Paula E Malone
    Department of Ophthalmology, Duke University Medical Center, Durham, NC 27710, USA
    Am J Ophthalmol 149:800-6.e1. 2010
    ....
  10. ncbi request reprint Fluocinolone acetonide implant (Retisert) for noninfectious posterior uveitis: thirty-four-week results of a multicenter randomized clinical study
    Glenn J Jaffe
    Duke University Eye Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ophthalmology 113:1020-7. 2006
    ..To report the interim 34-week safety and efficacy results of a 3-year study to evaluate an investigational intravitreal fluocinolone acetonide (FA) implant in patients with noninfectious posterior uveitis...
  11. doi request reprint Fluocinolone acetonide sustained drug delivery device for chronic central retinal vein occlusion: 12-month results
    Rajeev S Ramchandran
    Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina, USA
    Am J Ophthalmol 146:285-291. 2008
    ..To determine treatment outcomes of a long-acting intravitreal fluocinolone acetonide sustained drug delivery implant in eyes with central retinal vein occlusion (CRVO) and chronic refractory macular edema...
  12. doi request reprint Combined fluocinolone acetonide intraocular delivery system insertion, phacoemulsification, and intraocular lens implantation for severe uveitis
    Janet J Chieh
    Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Am J Ophthalmol 146:589-594. 2008
    ....
  13. ncbi request reprint Primary intraocular T-cell-rich large B-cell lymphoma
    Thomas J Cummings
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Arch Pathol Lab Med 129:1050-3. 2005
    ..This case highlights the importance of interpreting cytologic features in vitreous aspirates in the context of the clinical situation...
  14. ncbi request reprint Efficacy of low-release-rate fluocinolone acetonide intravitreal implants to treat experimental uveitis
    Prithvi Mruthyunjaya
    Department of Ophthalmology, Duke University Eye Center, Erwin Road, Durham, NC 27710, USA
    Arch Ophthalmol 124:1012-8. 2006
    ..To determine the efficacy of 0.5-mg and 0.1-mg sustained-release fluocinolone acetonide intravitreal implants to inhibit ocular inflammation in a rabbit model of severe uveitis...
  15. doi request reprint Retinal thickening in iridocyclitis
    Chelsea G Castellano
    Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina, USA
    Am J Ophthalmol 148:341-9. 2009
    ..To determine the frequency of retinal thickening (RT) in eyes with iridocyclitis and to examine the correlations among anterior chamber (AC) inflammation, RT, and visual acuity...
  16. ncbi request reprint Infliximab to treat chronic noninfectious uveitis in children: retrospective case series with long-term follow-up
    Stacy P Ardoin
    Division of Pediatric Rheumatology, Duke University Medical Center, Durham, NC 27710, USA
    Am J Ophthalmol 144:844-849. 2007
    ..To assess a response to infliximab therapy in childhood uveitis...
  17. ncbi request reprint Demographic-related variations in posterior segment ocular sarcoidosis
    Dara Khalatbari
    Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina, USA
    Ophthalmology 111:357-62. 2004
    ..To compare the frequency of posterior segment involvement (PSI), the prevalence of specific posterior segment signs, and visual acuity in ocular sarcoidosis by patient race, sex, and age...
  18. ncbi request reprint Evaluation of image artifact produced by optical coherence tomography of retinal pathology
    Robin Ray
    Department of Ophthalmology, Duke University Eye Center, Durham, North Carolina 27710, USA
    Am J Ophthalmol 139:18-29. 2005
    ..To determine the frequency and type of optical coherence tomography (OCT) fast macular thickness map (FMTM) scan artifacts, and whether these artifacts depend on patient diagnosis, demographics, and ocular therapy...
  19. ncbi request reprint Diagnostic yield of vitrectomy in eyes with suspected posterior segment infection or malignancy
    Prithvi Mruthyunjaya
    Department of Ophthalmology, Duke University Eye Center, Durham, North Carolina 27710, USA
    Ophthalmology 109:1123-9. 2002
    ..To determine the yield of diagnostic pars plana vitrectomy in eyes with suspected posterior segment inflammation or malignancy when clinical examination and systemic laboratory testing did not yield a specific diagnosis...
  20. ncbi request reprint Intravitreal triamcinolone acetonide in eyes with cystoid macular edema associated with central retinal vein occlusion
    Carl H Park
    Duke University Eye Center, Durham, North Carolina 27710, USA
    Am J Ophthalmol 136:419-25. 2003
    ..To evaluate treatment of cystoid macular edema associated with central retinal vein occlusion with intravitreal triamcinolone acetonide...
  21. doi request reprint Comparison of spectral- and time-domain optical coherence tomography for retinal thickness measurements in healthy and diseased eyes
    Ian C Han
    Duke Eye Center, Durham, North Carolina 27701, USA
    Am J Ophthalmol 147:847-58, 858.e1. 2009
    ..To compare retinal thickness (RT) measurements obtained by spectral-domain optical coherence tomography (SD-OCT) and time-domain OCT (TD-OCT) in eyes with and without posterior segment disease diagnoses...
  22. doi request reprint Evaluation of artifacts associated with macular spectral-domain optical coherence tomography
    Ian C Han
    Duke Eye Center, Duke University Medical Center, Durham, North Carolina, USA
    Ophthalmology 117:1177-1189.e4. 2010
    ....
  23. ncbi request reprint B-scan ultrasonography for the detection of macular thickening
    James C Lai
    Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Am J Ophthalmol 136:55-61. 2003
    ..To report the sensitivity and specificity of B-scan ultrasonography to detect macular thickening...
  24. ncbi request reprint Modified external needle drainage procedure for rhegmatogenous retinal detachment
    Glenn J Jaffe
    Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina, USA
    Retina 23:80-5. 2003
    ..To describe the results of a modified external needle subretinal fluid drainage technique to treat eyes with a rhegmatogenous retinal detachment...
  25. ncbi request reprint Prevalence and risk factors for proliferative vitreoretinopathy in eyes with rhegmatogenous retinal detachment but no previous vitreoretinal surgery
    Wendy Tseng
    Department of Ophthalmology, Duke University, Durham, North Carolina 27710, USA
    Am J Ophthalmol 137:1105-15. 2004
    ..To determine the prevalence of and risk factors for proliferatative vitreoretinopathy (PVR) in eyes with rhegmatogenous retinal detachment but no previous vitreoretinal surgery...
  26. ncbi request reprint Caspase-8-mediated apoptosis in human RPE cells
    Ping Yang
    Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Invest Ophthalmol Vis Sci 48:3341-9. 2007
    ..Herein, the authors investigated the role of caspase-8 in RPE cell resistance to TNF-alpha-mediated cell death...
  27. ncbi request reprint Optical coherence tomography reader agreement in neovascular age-related macular degeneration
    Nanfei Zhang
    Duke University Eye Center and the OCT Reading Center at Duke, Duke University Medical Center, Durham, North Carolina 27710, USA
    Am J Ophthalmol 144:37-44. 2007
    ..To determine the interreader and intrareader agreement at the Optical Coherence Tomography (OCT) Reading Center at Duke for images produced for an interventional neovascular age-related macular degeneration (AMD) clinical trial...
  28. ncbi request reprint Effect of mutant IkappaB on cytokine-induced activation of NF-kappaB in cultured human RPE cells
    Ping Yang
    Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Invest Ophthalmol Vis Sci 44:1339-47. 2003
    ..The persistence of recombinant protein expression and function after the viral infection was also examined...
  29. ncbi request reprint Human RPE expression of cell survival factors
    Ping Yang
    Departments of Ophthalmology, Duke University Medical Center, Durham, NC 27710, USA
    Invest Ophthalmol Vis Sci 46:1755-64. 2005
    ..To determine basal and tumor necrosis factor (TNF)-alpha-regulated expression of retinal pigment epithelial (RPE) cell survival factors and whether regulation is dependent on nuclear transcription factor (NF)-kappaB...
  30. ncbi request reprint Effect of NF-kappa B inhibition on TNF-alpha-induced apoptosis in human RPE cells
    Ping Yang
    Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Invest Ophthalmol Vis Sci 45:2438-46. 2004
    ....
  31. doi request reprint Treatment of posterior uveitis with a fluocinolone acetonide implant: three-year clinical trial results
    David G Callanan
    Texas Retina Associates, 1001 N Waldrop Dr, Ste 512, Arlington, TX 76012, USA
    Arch Ophthalmol 126:1191-201. 2008
    ..To evaluate the safety and efficacy of 0.59-mg and 2.1-mg fluocinolone acetonide (FA) intravitreous implants in noninfectious posterior uveitis...
  32. ncbi request reprint Intraocular pressure in patients with uveitis treated with fluocinolone acetonide implants
    Debra A Goldstein
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1905 W Taylor St, M C 648, Chicago, IL 60612, USA
    Arch Ophthalmol 125:1478-85. 2007
    ..To report the incidence and management of elevated intraocular pressure (IOP) in patients with uveitis treated with the fluocinolone acetonide (FA) intravitreal implant...
  33. ncbi request reprint Expression of a chemokine by ciliary body epithelium in horses with naturally occurring recurrent uveitis and in cultured ciliary body epithelial cells
    Brian C Gilger
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
    Am J Vet Res 63:942-7. 2002
    ..To determine whether a chemokine (RANTES)-like protein expressed by ciliary epithelium plays a role in uveitis...
  34. ncbi request reprint Diffuse unilateral subacute neuroretinitis in Venezuela
    Rafael Cortez
    Centro de Cirugía Oftalmológica, Caracas, Venezuela
    Ophthalmology 112:2110-4. 2005
    ..To describe the clinical features and management of the largest reported series to date of patients with diffuse unilateral subacute neuroretinitis (DUSN)...

Research Grants12

  1. Comparison of AMD Treatment Trials-OCT Reading Center
    GLENN JAFFE; Fiscal Year: 2007
    ....
  2. CYTOKINE MODULATION IN PROLIFERATIVE VITREORETINOPATHY
    GLENN JAFFE; Fiscal Year: 2005
    ..Density-dependent effects of IL-1, TNFalpha, and specific NF-kappaB inhibitors on NF-kappaB-mediated RPE apoptosis will be quantified. IV) To determine whether specific in vivo NF-kappaB blockade inhibits PVR. ..
  3. CYTOKINE MODULATION IN PROLIFERATIVE VITREORETINOPATHY
    GLENN JAFFE; Fiscal Year: 2000
    ....