CELIA HYBELS

..Our objective was to examine the association between neighborhood context and level of depressive symptomatology in older adults in a diverse geographic region of central North Carolina...

..To determine the risk of disability in individuals with coexisting visual and cognitive impairment and to compare the magnitude of risk associated with visual impairment, cognitive impairment, or the multimorbidity...

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..The aim of the study was to compare symptom expression in primarily middle-aged (<60) and older (60+) patients who were depressed and determine if symptom profiles differed by age...

..Our aim was to explore the latent traits of trajectories of limitations in mobility and instrumental activities of daily living (IADL) tasks in a sample of older adults diagnosed with major depression...

..To explore the underlying structure of symptom presentation in older adults with major depression by identifying homogeneous clusters of individuals based on symptom profiles...

..Less is known about the impact of subthreshold depression, and whether more symptoms confer significantly greater risk compared to fewer symptoms...

..To examine the course of depressive symptoms in older patients with comorbid major depression and dysthymia...

..The purpose of this study was to identify residual symptoms in a sample of older adults treated for major depression and compare individual symptoms present at baseline with those at three months by remission status...

..We explored the demographic and risk factor profiles of two groups, one with more severe depression and one with less severe depression...

..The authors studied demographic, clinical, social, and perceived health and well-being factors as predictors of partial remission in older patients treated for major depressive disorder (MDD)...

..60; p=0.002) across the three periods. Subthreshold depression may result in different outcomes in women, possibly mediating against mortality...

..Also included is a discussion of risk factors and outcomes of these disorders and a discussion of the implications of these epidemiologic findings for geriatric medicine...

..The apolipoprotein E gene (APOE) epsilon 4 allele has been associated with a variety of late-life neuropsychiatric disorders, including Alzheimer's disease, vascular dementia, and depression...

..We attempted to determine if self-reported shortness of breath (SoB) is associated with depressive symptoms at long-term (3-year) follow-up in a community sample of older (65+) adults...

..To determine which symptoms of depression are most likely to increase the risk of mortality in a biracial sample of older adults...

..We sought to determine whether, among older adults (>65 years), a perception that their basic needs are not being met increased mortality risk and whether this risk varied by race/ethnicity...

..In this study, we determined, controlling for reported income and functional status, if perceived inadequate basic needs predicted depressive symptoms...

..The authors sought to examine the association of vascular nutritional factors and depression in an elderly cohort of depression (currently and recently depressed) and comparison (never depressed) subjects...

..To determine whether the characteristics of the usual medical care providers of older antidepressant users changed between 1986 and 1997 with the introduction of selective serotonin reuptake inhibitors...

..The authors analyzed data from two follow-up intervals-1986-1987 to 1989-1990 (interval 1) and 1992-1993 to 1996-1997 (interval 2)-from a community-based cohort of 4,162 older adults to determine predictors of future antidepressant use...

..To determine whether metabolic syndrome is an independent predictor of decline in mobility in an elderly community sample...

..Despite the burden of depression in late life, its origins present a paradox to investigators and clinicians alike...

..Treatment options include antidepressants (alone or in combination) and psychotherapy...

..Data from the Duke Established Populations of Epidemiologic Studies of the Elderly (EPESE) will be used to develop the model and address the dynamics of the depression and functioning relationship. ..

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