Kim M Huffman

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness
    Kim M Huffman
    Physical Medicine and Rehabilitation Service, Veterans Affairs Medical Center, Durham, NC, USA
    Diabetologia 57:2282-95. 2014
  2. pmc Impact of baseline physical activity and diet behavior on metabolic syndrome in a pharmaceutical trial: results from NAVIGATOR
    Kim M Huffman
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA Veteran Affairs Medical Center, Durham, NC, USA Electronic address
    Metabolism 63:554-61. 2014
  3. pmc Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial
    Kim M Huffman
    Physical Medicine and Rehabilitation, Veterans Affairs Medical Center, Durham, North Carolina, United States of America
    PLoS ONE 7:e28190. 2012
  4. pmc Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity
    Kim M Huffman
    Physical Medicine and Rehabilitation, Veterans Affairs Medical Center, Durham, North Carolina, USA
    Diabetes Care 34:174-6. 2011
  5. pmc Is diabetes associated with poorer self-efficacy and motivation for physical activity in older adults with arthritis?
    K M Huffman
    Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Scand J Rheumatol 39:380-6. 2010
  6. pmc The impact of self-reported arthritis and diabetes on response to a home-based physical activity counselling intervention
    K M Huffman
    Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Scand J Rheumatol 39:233-9. 2010
  7. pmc Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women
    Kim M Huffman
    Physical Medicine and Rehabilitation, Veterans Affairs Medical Center, Durham, North Carolina, USA
    Diabetes Care 32:1678-83. 2009
  8. pmc Impact of hormone replacement therapy on exercise training-induced improvements in insulin action in sedentary overweight adults
    Kim M Huffman
    Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Metabolism 57:888-95. 2008
  9. pmc Relationships between adipose tissue and cytokine responses to a randomized controlled exercise training intervention
    Kim M Huffman
    Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Metabolism 57:577-83. 2008
  10. pmc Dietary carbohydrate intake and high-sensitivity C-reactive protein in at-risk women and men
    Kim M Huffman
    Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Am Heart J 154:962-8. 2007

Detail Information

Publications22

  1. ncbi request reprint Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness
    Kim M Huffman
    Physical Medicine and Rehabilitation Service, Veterans Affairs Medical Center, Durham, NC, USA
    Diabetologia 57:2282-95. 2014
    ..We hypothesised that changes in mitochondrial metabolic intermediates would predict improvements in clinical risk factors, thereby offering novel insights into potential mechanisms...
  2. pmc Impact of baseline physical activity and diet behavior on metabolic syndrome in a pharmaceutical trial: results from NAVIGATOR
    Kim M Huffman
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA Veteran Affairs Medical Center, Durham, NC, USA Electronic address
    Metabolism 63:554-61. 2014
    ..Each can be affected by physical activity and diet. Our objective was to determine whether determine whether baseline physical activity and/or diet behavior impact MS in the course of a large pharmaceutical trial...
  3. pmc Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial
    Kim M Huffman
    Physical Medicine and Rehabilitation, Veterans Affairs Medical Center, Durham, North Carolina, United States of America
    PLoS ONE 7:e28190. 2012
    ....
  4. pmc Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity
    Kim M Huffman
    Physical Medicine and Rehabilitation, Veterans Affairs Medical Center, Durham, North Carolina, USA
    Diabetes Care 34:174-6. 2011
    ..To understand relationships between exercise training-mediated improvements in insulin sensitivity (S(I)) and changes in circulating concentrations of metabolic intermediates, hormones, and inflammatory mediators...
  5. pmc Is diabetes associated with poorer self-efficacy and motivation for physical activity in older adults with arthritis?
    K M Huffman
    Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Scand J Rheumatol 39:380-6. 2010
    ..A further objective was to determine whether the added burden of diabetes contributes to a further reduction in these PA determinants and types...
  6. pmc The impact of self-reported arthritis and diabetes on response to a home-based physical activity counselling intervention
    K M Huffman
    Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Scand J Rheumatol 39:233-9. 2010
    ..Our objective was to explore whether persons with arthritis alone or those with both arthritis and diabetes could improve amounts of PA with a home-based counselling intervention...
  7. pmc Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women
    Kim M Huffman
    Physical Medicine and Rehabilitation, Veterans Affairs Medical Center, Durham, North Carolina, USA
    Diabetes Care 32:1678-83. 2009
    ..To determine whether circulating metabolic intermediates are related to insulin resistance and beta-cell dysfunction in individuals at risk for type 2 diabetes...
  8. pmc Impact of hormone replacement therapy on exercise training-induced improvements in insulin action in sedentary overweight adults
    Kim M Huffman
    Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Metabolism 57:888-95. 2008
    ..These findings have implications for the relative utility of ET for improving insulin action in middle-aged men and women, particularly in the setting of differences in HRT use...
  9. pmc Relationships between adipose tissue and cytokine responses to a randomized controlled exercise training intervention
    Kim M Huffman
    Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Metabolism 57:577-83. 2008
    ..In contradiction to our hypothesis, despite significant alterations in body composition, exercise training produced limited cytokine responses...
  10. pmc Dietary carbohydrate intake and high-sensitivity C-reactive protein in at-risk women and men
    Kim M Huffman
    Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Am Heart J 154:962-8. 2007
    ..Our objective was to determine if GL is related to hsCRP and other measures of CVD risk in a population of sedentary, overweight, dyslipidemic middle-aged women and men enrolled in an exercise intervention trial (STRRIDE)...
  11. pmc Relations of a marker of endothelial activation (s-VCAM) to function and mortality in community-dwelling older adults
    Kim M Huffman
    Department of Physical Medicine and Rehabilitation, Veterans Affairs Medical Center, Durham, NC, USA
    J Gerontol A Biol Sci Med Sci 66:1369-75. 2011
    ....
  12. ncbi request reprint Response of high-sensitivity C-reactive protein to exercise training in an at-risk population
    Kim M Huffman
    Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Am Heart J 152:793-800. 2006
    ..Our objective was to determine if modulating fitness with exercise training imposes changes in high-sensitivity C-reactive protein in a mixed-sex population at risk for cardiovascular disease...
  13. pmc Enhanced fitness: a randomized controlled trial of the effects of home-based physical activity counseling on glycemic control in older adults with prediabetes mellitus
    Miriam C Morey
    Geriatric Research, Education, and Clinical Center, Veterans Affairs Medical Center, Durham, North Carolina 27705, USA
    J Am Geriatr Soc 60:1655-62. 2012
    ..To determine whether a home-based multicomponent physical activity counseling (PAC) intervention is effective in reducing glycemic measures in older outpatients with prediabetes mellitus...
  14. pmc Exercise effects on lipids in persons with varying dietary patterns-does diet matter if they exercise? Responses in Studies of a Targeted Risk Reduction Intervention through Defined Exercise I
    Kim M Huffman
    Division of Rheumatology, Duke University Medical Center, Durham, NC, USA
    Am Heart J 164:117-24. 2012
    ..The purpose of the current study was to determine if, across a range of dietary patterns, there were variable lipoprotein responses to an aerobic exercise training intervention...
  15. pmc Effects of exercise training intensity on pancreatic beta-cell function
    Cris A Slentz
    Division of Cardiovascular Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Diabetes Care 32:1807-11. 2009
    ..Insulin resistance and beta-cell dysfunction both are important contributors to the pathogenesis of type 2 diabetes. Exercise training improves insulin sensitivity, but its effects on beta-cell function are less well studied...
  16. pmc Sex-specific alterations in mRNA level of key lipid metabolism enzymes in skeletal muscle of overweight and obese subjects following endurance exercise
    Ira J Smith
    Center for the Study of Aging, Duke University Medical Center, Durham, North Carolina 27710, USA
    Physiol Genomics 36:149-57. 2009
    ..Future studies should determine whether these adaptations in mRNA levels translate into changes in protein function...
  17. pmc Plasma acylcarnitines are associated with physical performance in elderly men
    Helen Lum
    Department of Medicine, Division of Geriatrics, Gerontology and Palliative Medicine, University of Texas Health Science Center, San Antonio, USA
    J Gerontol A Biol Sci Med Sci 66:548-53. 2011
    ..Metabolic profiling might provide insight into the biologic underpinnings of disability in older adults...
  18. pmc Effects of aerobic vs. resistance training on visceral and liver fat stores, liver enzymes, and insulin resistance by HOMA in overweight adults from STRRIDE AT/RT
    Cris A Slentz
    Div of Cardiology, Dept of Medicine, PO Box 3022, Duke Univ Medical Center, Durham, NC 27710, USA
    Am J Physiol Endocrinol Metab 301:E1033-9. 2011
    ....
  19. ncbi request reprint Adipose depots, not disease-related factors, account for skeletal muscle insulin sensitivity in established and treated rheumatoid arthritis
    Hiba Abouassi
    From the Divisions of Endocrinology, Rheumatology and Immunology, Cardiology, Geriatrics, Department of Medicine and Duke Molecular Physiology Institute, Duke University Medical Center Durham Veterans Affairs Medical Center, Durham, North Carolina, USA H AbouAssi, MD, Division of Endocrinology K N Tune, BA, Division of Rheumatology and Immunology B Gilmore, BS L A Bateman, MS, Division of Cardiology G McDaniel, PA, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center M Muehlbauer, PhD J L Huebner, MS, Duke Molecular Physiology Institute, Duke University Medical Center H M Hoenig, MD, Division of Geriatrics, Department of Medicine, Duke University Medical Center, Veterans Affairs Medical Center V B Kraus, MD, PhD, Division of Rheumatology and Immunology, Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center E W St Clair, MD, Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center W E Kraus, MD, Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Livilands Gate
    J Rheumatol 41:1974-9. 2014
    ..Our objectives were to carefully assess, compare, and determine predictors of skeletal muscle insulin sensitivity in RA, accounting for adiposity and physical activity...
  20. pmc Critical appraisal of four IL-6 immunoassays
    Dana K Thompson
    Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America
    PLoS ONE 7:e30659. 2012
    ..Serial plasma samples from intravenous glucose tolerance tests (IVGTTs), with expected rises in IL-6 concentrations, were used to test the face validity of the various assays...
  21. ncbi request reprint Alpha C-telopeptide of type I collagen is associated with subchondral bone turnover and predicts progression of joint space narrowing and osteophytes in osteoarthritis
    Janet L Huebner
    Duke University School of Medicine, Durham, North Carolina
    Arthritis Rheumatol 66:2440-9. 2014
    ....
  22. pmc Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation
    Anna E Denoble
    Departments of Medicine and Radiology Duke University Medical Center, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 108:2088-93. 2011
    ....