Research Topics
| Cathrine HoyoSummaryAffiliation: Duke University Medical Center Country: USA Publications
Research Grants
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Detail Information
Publications
Body mass index in relation to oesophageal and oesophagogastric junction adenocarcinomas: a pooled analysis from the International BEACON ConsortiumCathrine Hoyo
Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC 27710, USA
Int J Epidemiol 41:1706-18. 2012..However, these studies have been limited in their ability to assess whether the effects of obesity vary by gender or by the presence of gastro-oesophageal reflux (GERD) symptoms...- Association of cord blood methylation fractions at imprinted insulin-like growth factor 2 (IGF2), plasma IGF2, and birth weightCathrine Hoyo
Department of Community and Family Medicine, Duke University Medical Center, 2200 West Main Street, Ste 600, Durham, NC 27705, USA
Cancer Causes Control 23:635-45. 2012..We examined associations among DNA methylation at IGF2 differentially methylated regions (DMRs), circulating IGF2 protein concentrations in umbilical cord blood (UCB) and birth weight in newborns... - The effects of depression and use of antidepressive medicines during pregnancy on the methylation status of the IGF2 imprinted control regions in the offspringA Soubry
Duke Cancer Institute, Duke University Medical Center, Durham, NC, USA
Clin Epigenetics 3:2. 2011..05%, p = 0.01). In conclusion, our findings suggest a race-dependent response related to maternal use of antidepressants at one of the IGF2 DMRs in the offspring... - Folic acid supplementation before and during pregnancy in the Newborn Epigenetics STudy (NEST)Cathrine Hoyo
Department of Community and Family Medicine and Program of Cancer Detection, Prevention and Control, Duke University, PO Box 104006, Durham, NC 27710, USA
BMC Public Health 11:46. 2011..The primary objective is to estimate the proportion of women taking folic acid (FA) doses exceeding the TUL before and during pregnancy, and to identify correlates of high FA use... - Methylation variation at IGF2 differentially methylated regions and maternal folic acid use before and during pregnancyCathrine Hoyo
Department of Community and Family Medicine, Duke University Medical Center, Durham, NC, USA
Epigenetics 6:928-36. 2011.... - Distribution of HPV genotypes in cervical intraepithelial lesions and cervical cancer in Tanzanian womenAdriana C Vidal
Department of Community and Family Medicine, and Program of Cancer Detection, Prevention and Control, Duke University School of Medicine, Durham, NC, USA
Infect Agent Cancer 6:20. 2011..abstract:.. - Predictors of variation in serum IGF1 and IGFBP3 levels in healthy African American and white menCathrine Hoyo
Department of Community and Family Medicine, Duke University Medical Center, Box 2914, Durham, NC 27710, USA
J Natl Med Assoc 101:711-6. 2009..Factors associated with variation in circulating levels of these peptide hormones remain unclear... - Grade-specific prostate cancer associations of IGF1 (CA)19 repeats and IGFBP3-202A/C in blacks and whitesCathrine Hoyo
Department of Community and Family Medicine, Hanes House Room 347, Trent Drive, Box 2914, Medical Center, Duke University Medical Center, Durham, NC 27710, USA
J Natl Med Assoc 99:718-22. 2007..If confirmed in larger studies, these findings support the hypothesis that the association between IGFBP3 C allele and prostate cancer is grade specific in both ethnic groups... - Gender-specific methylation differences in relation to prenatal exposure to cigarette smokeSusan K Murphy
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Duke University Medical Center, Durham, NC 27708, USA
Gene 494:36-43. 2012..Our findings suggest that IGF2 DMR plasticity is an important mechanism by which in utero adjustments to environmental toxicants are conferred. Larger studies to replicate these findings are required... - Depression in pregnancy, infant birth weight and DNA methylation of imprint regulatory elementsYing Liu
School of Medicine, Duke University, Durham, NC, USA
Epigenetics 7:735-46. 2012..9% higher methylation at the PLAGL1 DMR compared with normal birth weight infants. Our findings confirm that severe maternal depressed mood in pregnancy is associated with LBW, and that MEG3 and IGF2 plasticity may play important roles... - Insulin-like growth factor 2/H19 methylation at birth and risk of overweight and obesity in childrenEllen Perkins
Department of Community and Family Medicine, Duke University, Durham, NC 27710, USA
J Pediatr 161:31-9. 2012..To determine whether aberrant DNA methylation at differentially methylated regions (DMRs) regulating insulin-like growth factor 2 (IGF2) expression in umbilical cord blood is associated with overweight or obesity in a multiethnic cohort... 
Vitamin D receptor (VDR) polymorphisms and risk of ovarian cancer in Caucasian and African American womenDelores J Grant
Department of Biology and Cancer Research Program, JLC Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, NC, USA
Gynecol Oncol 129:173-8. 2013..Polymorphisms in the vitamin D receptor (VDR) gene have been shown in some studies to be associated with the risk of epithelial ovarian cancer (EOC) in Caucasian women. There are no published reports among African Americans...- Association between exercise and primary incidence of prostate cancer: does race matter?Abhay A Singh
Duke Prostate Center, Duke University Medical Center, Durham, NC 27705, USA
Cancer 119:1338-43. 2013..However, whether this association is different as a function of race is unclear. In the current study, the authors attempted to characterize the link between exercise and prostate cancer (CaP) in white and black American men... - IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and WhitesCathrine Hoyo
Department of Community and Family Medicine, and Program of Cancer Detection, Prevention and Control, Duke University Medical Center, NC, USA
Dis Markers 32:133-41. 2012..5002 G>A modulates IGF2 circulating levels in a sex-specific manner, and while carrying the IGF2R c.901 C>G may increase cancer risk, the mechanism may not involve modulation of circulating IGF2... - Dietary calcium and risk for prostate cancer: a case-control study among US veteransChristina D Williams
Durham Veterans Affairs Medical Center, 508 Fulton St, HSRD 152, Durham, NC 27705, USA
Prev Chronic Dis 9:E39. 2012..The objective of this study was to examine the association between calcium intake and prostate cancer risk. We hypothesized that calcium intake would be positively associated with lower risk for prostate cancer... - IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomasCathrine Hoyo
Department of Community and Family Medicine, Duke University, Durham, NC 27710, USA
Int J Cancer 125:2673-8. 2009..5002G > A genotype and EGA was not evident. These findings suggest that nonsynonymous polymorphisms in M6P/IGF2R may contribute to the risks of EGA and noncardia adenocarcinomas. Larger studies are required to confirm these findings... - Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohortAdelheid Soubry
Duke Cancer Institute, Duke University Medical Center 2715, Durham, NC 27710, USA
BMC Med 11:29. 2013.... 
Pain predicts non-adherence to pap smear screening among middle-aged African American womenCathrine Hoyo
Department of Community and Family Medicine, Duke University Medical Center, Box 2914, Durham, NC 27710, USA
Prev Med 41:439-45. 2005..Middle-aged African American women have the highest incidence and mortality of invasive cervical cancer in the United States and the lowest adherence to pap smear screening...- Associations between methylation of paternally expressed gene 3 (PEG3), cervical intraepithelial neoplasia and invasive cervical cancerMonica D Nye
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, North Carolina, United States of America
PLoS ONE 8:e56325. 2013..6-fold increase ICC risk. Suggesting PEG3 methylation status may be useful as a molecular marker for CIN screening to improve prediction of cases likely to progress... - Differentially methylated regions of imprinted genes in prenatal, perinatal and postnatal human tissuesSusan K Murphy
Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, United States of America
PLoS ONE 7:e40924. 2012..Similarity of inter-individual and intra-individual methylation at some, but not all of the DMRs analyzed supports the possibility that methylation of these regions can serve as useful biosensors of exposure... - Racial differences in enrolment in a cancer genetics registryPatricia G Moorman
Cancer Prevention Detection and Control Research Program, Duke University Medical Center, 239 Hanes House, Trent Drive, Box 2949, Durham, NC 27710, USA
Cancer Epidemiol Biomarkers Prev 13:1349-54. 2004..Most studies have little information about nonparticipants, making it difficult to identify characteristics associated with enrolment and how they might vary by race... - Anthropometric measurements and epithelial ovarian cancer risk in African-American and White womenCathrine Hoyo
Department of Community and Family Medicine, Duke University Medical Center, 2424 Erwin Rd, Hock Plaza, Ste 602, Durham, NC 27710, USA
Cancer Causes Control 16:955-63. 2005..0; 95% CI = 0.7-1.4). These findings support the hypothesis that obesity is an important risk factor of ovarian cancer among African-Americans and Whites and also suggest that height may be a risk factor specific to African-Americans... - IGF1 (CA)19 repeat and IGFBP3 -202 A/C genotypes and the risk of prostate cancer in Black and White menJoellen M Schildkraut
Program of Cancer Prevention, Detection and Control Research, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC, USA
Cancer Epidemiol Biomarkers Prev 14:403-8. 2005..Further research is needed to confirm these findings... - The association of diabetes mellitus and high-grade prostate cancer in a multiethnic biopsy seriesDaniel M Moreira
Division of Urologic Surgery, Department of Surgery and Duke Prostate Center, Duke University School of Medicine, Durham, NC, USA
Cancer Causes Control 22:977-83. 2011..To analyze the association of diabetes mellitus (DM) with risk of prostate cancer and cancer grade among men undergoing prostate biopsy and to analyze how obesity and race modify these associations... - DNA methylation at imprint regulatory regions in preterm birth and infectionYing Liu
Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC
Am J Obstet Gynecol 208:395.e1-7. 2013.... - Elevated C-peptide and insulin predict increased risk of colorectal adenomas in normal mucosaAdriana C Vidal
Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, North Carolina, USA
BMC Cancer 12:389. 2012..However few studies have evaluated IGFBP-1 and C-peptide in relation to adenomatous polyps, the only known precursor for CRC... - A high ratio of dietary n-6/n-3 polyunsaturated fatty acids is associated with increased risk of prostate cancerChristina D Williams
Division of General Internal Medicine, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Nutr Res 31:1-8. 2011..In conclusion, our findings suggest that a high dietary ratio of n-6/n-3 fatty acids may increase the risk of overall prostate cancer among white men and possibly increase the risk of high-grade prostate cancer among all men... - Barriers and strategies for sustained participation of African-American men in cohort studiesCathrine Hoyo
Department of Health Education, North Carolina Central University, Durham 27707, USA
Ethn Dis 13:470-6. 2003.... - Improving the accuracy of syndromic diagnosis of genital ulcer disease in MalawiCathrine Hoyo
Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Sex Transm Dis 32:231-7. 2005..However, the etiologic pathogens of GUD vary temporally and geographically, and current criteria may not reflect changes in the prevalence of specific pathogens... - Reproducibility of self-reported pap test utilization in middle-aged African-American womenCathrine Hoyo
Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
Ethn Dis 15:84-9. 2005..Not using self-reports to base clinic decisions may still be prudent among those with less education... - Association of uridine diphosphate-glucuronosyltransferase 2B gene variants with serum glucuronide levels and prostate cancer riskDelores J Grant
Cancer Research Program and Department of Biology, Julius L Chambers Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, North Carolina 27707, USA
Genet Test Mol Biomarkers 17:3-9. 2013..The functional significance of the UGT2B genetic variants has never been described in humans. We evaluated UGT2B variants in relation to plasma androstane-3α,17β-diol-glucuronide (AAG) levels and the prostate cancer risk... - Program prioritization to control chronic diseases in African-American faith-based communitiesCathrine Hoyo
Duke University Medical Center, Department of Community and Family Medicine, Durham, North Carolina, USA
J Natl Med Assoc 96:524-32. 2004..We assessed the effect of providing congregation leaders with skills on identifying their own health needs, planning, and implementing their own interventions... - Key attributes of health ministries in African American churches: an exploratory surveyLori Carter-Edwards
Institute for Health, Social and Community Research at Shaw University, USA
N C Med J 67:345-50. 2006..However it is unknown which program attributes they perceive as important and which program attributes exist in their congregations... - For the patient. Recruitment strategies for cancer research studiesKyna M Gooden
Ethn Dis 15:151. 2005 - Perceptions of participation in an observational epidemiologic study of cancer among African AmericansKyna M Gooden
Department of Epidemiology, University of North Carolina at Chapel Hill, 2101 McGavran-Greenberg Hall, CB#7435, Chapel Hill, NC 26599, USA
Ethn Dis 15:68-75. 2005..However, culturally appropriate efforts to thoroughly inform them of study process and progress are deemed essential for successful recruitment and retention... - For the patient. Improving participation of African-American men in research studiesCathrine Hoyo
Ethn Dis 13:547-8. 2003 - The prevalence and correlates of urinary tract symptoms in Norwegian men: the HUNT studyArnfinn Seim
Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway
BJU Int 96:88-92. 2005....
Research Grants
- Insulin-like Growth Factors and Esophageal CancerCathrine Hoyo; Fiscal Year: 2007..abstract_text> ..
- In-utero Exposure and Infant Loss of IGF2 ImprintingCathrine Hoyo; Fiscal Year: 2007..The proposed study also has the potential to provide a foundation for future studies investigating the etiology of chronic diseases, including diabetes, cardiovascular diseases and some cancers. ..
- Nutrition, Deregulation of Imprinted GenesCathrine Hoyo; Fiscal Year: 2009....
- Disparities in cervical cancer precursors and deregulation of imprinted genesSusan Kay Murphy; Fiscal Year: 2010..Data from this study will elucidate the role of epigenetic deregulation in CIN2+ and inform triage decisions, reducing disparities in cervical cancer incidence and mortality. ..
- Nutrition, Deregulation of Imprinted GenesCathrine Hoyo; Fiscal Year: 2010....
- Nutrition, Deregulation of Imprinted GenesCathrine Hoyo; Fiscal Year: 2009....
- Obesity and deregulation of imprinted genes in early lifeSusan Kay Murphy; Fiscal Year: 2010....