Anne S Hellkamp
Affiliation: Duke University Medical Center
- Treatment crossovers did not affect randomized treatment comparisons in the Mode Selection Trial (MOST)Anne S Hellkamp
Duke Clinical Research Institute, Durham, North Carolina, USA
J Am Coll Cardiol 47:2260-6. 2006..We evaluated the impact of treatment crossovers on study results in the Mode Selection Trial (MOST)...
- Mortality benefits from implantable cardioverter-defibrillator therapy are not restricted to patients with remote myocardial infarction: an analysis from the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)Jonathan P Piccini
Division of Cardiology, Duke University Medical Center, Durham, North Carolina 27710, USA
Heart Rhythm 8:393-400. 2011....
- Influenza vaccination of household contacts of newborns: a hospital-based strategy to increase vaccination ratesEmmanuel B Walter
Duke Clinical Vaccine Unit and Primary Care Research Consortium, Duke University Medical Center, Durham, NC 27704, USA
Infect Control Hosp Epidemiol 31:1070-3. 2010..7% were vaccinated through the program, as were 25.7% of fathers. A hospital-based program provided opportunities for vaccination of household contacts of newborns, thereby facilitating better adherence to national vaccination guidelines...
- Comparing classifications of death in the Mode Selection Trial: agreement and disagreement among site investigators and a clinical events committeeJohn L Petersen
Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA
Contemp Clin Trials 27:260-8. 2006..These findings support continued use of CECs for endpoint adjudication in clinical trials...
- Outcomes of discontinuing rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: analysis from the ROCKET AF trial (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention oManesh R Patel
Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
J Am Coll Cardiol 61:651-8. 2013..The purpose of this study was to understand the possible risk of discontinuation in the context of clinical care...
- End of study transition from study drug to open-label vitamin K antagonist therapy: the ROCKET AF experienceKenneth W Mahaffey
Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
Circ Cardiovasc Qual Outcomes 6:470-8. 2013..To evaluate the previously reported excess of thromboembolic events during the 30 days after the end of study (EOS) visit when participants transitioned from blinded therapy to open-label vitamin K antagonist...
- Trends in use of implantable cardioverter-defibrillator therapy among patients hospitalized for heart failure: have the previously observed sex and racial disparities changed over time?Sana M Al-Khatib
MHS, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
Circulation 125:1094-101. 2012..The degree to which the overall use of ICD therapy and disparities in use have changed is unclear...
- Implantable cardioverter defibrillator therapy in patients with prior coronary revascularization in the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)Sana M Al-Khatib
Duke Clinical Research Institute, Durham, North Carolina 27705, USA
J Cardiovasc Electrophysiol 19:1059-65. 2008....
- Optimal duration of eptifibatide infusion in percutaneous coronary intervention (an ESPRIT substudy)Abdallah G Rebeiz
Duke Clinical Research Institute, Durham, North Carolina, USA
Am J Cardiol 94:926-9. 2004....
- Adverse effect of ventricular pacing on heart failure and atrial fibrillation among patients with normal baseline QRS duration in a clinical trial of pacemaker therapy for sinus node dysfunctionMichael O Sweeney
Cardiac Arrhythmia Service, Brigham and Women s Hospital and Harvard Medical School, 75 Francis St, Boston, Mass 02115, USA
Circulation 107:2932-7. 2003..The effect of pacing-induced ventricular desynchronization in patients with normal baseline QRSd is unknown...
- Atrial high rate episodes detected by pacemaker diagnostics predict death and stroke: report of the Atrial Diagnostics Ancillary Study of the MOde Selection Trial (MOST)Taya V Glotzer
Division of Electrophysiology, Hackensack University Medical Center, Hackensack, NJ, USA
Circulation 107:1614-9. 2003..The purpose of the study was to correlate atrial high rate events (AHREs) detected by pacemaker diagnostics with clinical outcomes...
- Complications arising after implantation of DDD pacemakers: the MOST experienceKenneth A Ellenbogen
Division of Cardiology, Medical College of Virginia, PO Box 980053, Richmond, VA 23298 0053, USA
Am J Cardiol 92:740-1. 2003..This information may serve as a benchmark when comparing complication rates for dual-chamber pacemaker implantation with those for biventricular pacemaker implantation...
- Prognostic importance of defibrillator shocks in patients with heart failureJeanne E Poole
Division of Cardiology, University of Washington School of Medicine, 1959 NE Pacific St, Box 356422, Seattle, WA 98195 6422, USA
N Engl J Med 359:1009-17. 2008..e., prevention of a first life-threatening arrhythmic event) may later receive therapeutic shocks from the ICD. Information about long-term prognosis after ICD therapy in such patients is limited...
- Outcome in African Americans and other minorities in the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)Judith E Mitchell
State University of New York Downstate Medical Center, Brooklyn, NY 11203, USA
Am Heart J 155:501-6. 2008..The purpose of this report is to describe the outcomes in African Americans (AAs) and other minorities...
- Characterization and prognostic value of persistent hyponatremia in patients with severe heart failure in the ESCAPE TrialMihai Gheorghiade
Division of Cardiology, Northwestern University, Feinberg School of Medicine, 201 E Huron Street, Chicago, IL 60611, USA
Arch Intern Med 167:1998-2005. 2007..To our knowledge, the association of hyponatremia with outcomes has not been evaluated in the context of in-hospital clinical course including central hemodynamics and changes in serum sodium level...
- Where patients with mild to moderate heart failure die: results from the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)Brian Olshansky
Department of Internal Medicine, University of Iowa Hospitals, 4426A JCP, 200 Hawkins Dr, Iowa City, IA 52242, USA
Am Heart J 153:1089-94. 2007..In the SCD-HeFT, mortality of patients with CHF was assessed after randomization to an implantable cardioverter/defibrillator (ICD), amiodarone, or placebo. The aim of this study was to evaluate the location of deaths in SCD-HeFT...
- Risk of thromboembolism in heart failure: an analysis from the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)Ronald S Freudenberger
Department of Medicine, Robert Wood Johnson Medical School, Suite 6100, 125 Paterson St, New Brunswick, NJ 08903, USA
Circulation 115:2637-41. 2007..In the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT), 2521 patients with moderate heart failure were randomized to receive amiodarone, implanted cardioverter-defibrillators (ICDs), or placebo...
- Role of amiodarone or implantable cardioverter/defibrillator in patients with atrial fibrillation and heart failureSteven N Singh
Department of Veterans Affairs Medical Center, Washington, DC 20422, USA
Am Heart J 152:974.e7-11. 2006..The aim of the study was to determine the role of amiodarone or implantable cardioverter/defibrillator (ICD) in patients with AF and heart failure...
- Predictors of stroke in patients paced for sick sinus syndromeArnold J Greenspon
Division of Cardiology, Jefferson Medical College and Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA
J Am Coll Cardiol 43:1617-22. 2004..This study was an analysis of factors associated with stroke in a population of patients paced for sinus node dysfunction in a large prospective clinical trial (Mode Selection Trial [MOST])...
- Heart failure during cardiac pacingMichael O Sweeney
Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Circulation 113:2082-8. 2006..The adverse effects of ventricular desynchronization may explain the association of RVA pacing with an increased risk of heart failure hospitalization (HFH) in clinical trials...
- High incidence of pacemaker syndrome in patients with sinus node dysfunction treated with ventricular-based pacing in the Mode Selection Trial (MOST)Mark S Link
Tufts New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
J Am Coll Cardiol 43:2066-71. 2004..We evaluated the incidence, predictors, and treatment of pacemaker syndrome in patients with sinus node dysfunction treated with ventricular-based (VVIR) pacing in the Mode Selection Trial (MOST)...
- The association of the heart failure score with mortality and heart failure hospitalizations in elderly patients: insights from the Mode Selection Trial (MOST)Eldrin F Lewis
Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Am Heart J 151:699-705. 2006..This trend risks masking the severity and prevalence of HF as hospitalization for HF may decrease...
- Association of prolonged QRS duration with death in a clinical trial of pacemaker therapy for sinus node dysfunctionMichael O Sweeney
Cardiac Arrhythmia Service, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
Circulation 111:2418-23. 2005..The relationship of baseline QRSd to death and heart failure hospitalization in patients with sinus node dysfunction who require pacemaker therapy is unknown...
- Heart failure hospitalization is more common in pacemaker patients with sinus node dysfunction and a prolonged paced QRS durationHimanshu H Shukla
University of Missouri Columbia, Columbia, Missouri, USA
Heart Rhythm 2:245-51. 2005..The purpose of this study was to determine whether a prolonged paced QRS duration increases the risk of cardiac dysfunction...
- Ventricular pacing or dual-chamber pacing for sinus-node dysfunctionGervasio A Lamas
Division of Cardiology, Mount Sinai Medical Center, and the University of Miami School of Medicine, Miami Beach, Fla, USA
N Engl J Med 346:1854-62. 2002..However, it is unknown which type of pacing results in the better outcome...