Research Topics
| Bradley G HammillSummaryAffiliation: Duke University Medical Center Country: USA Publications
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Detail Information
Publications
Performance of propensity score methods when comparison groups originate from different data sourcesBradley G Hammill
Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
Pharmacoepidemiol Drug Saf 21:81-9. 2012..To examine the performance of propensity score-based methods for estimating relative risks when exposed and comparison subjects are selected from different data sources...- Incremental value of clinical data beyond claims data in predicting 30-day outcomes after heart failure hospitalizationBradley G Hammill
Duke Clinical Research Institute and Department of Medicine, Duke University School of Medicine, Durham, NC 27715, USA
Circ Cardiovasc Qual Outcomes 4:60-7. 2011..As clinical data become more readily available, the incremental value of adding clinical data to claims-based models of mortality and readmission is unclear... 
Relationship between cardiac rehabilitation and long-term risks of death and myocardial infarction among elderly Medicare beneficiariesBradley G Hammill
Center for Clinical and Genetic Economics, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
Circulation 121:63-70. 2010..The relationship between the number of sessions attended and long-term outcomes is unknown...- Associations between aldosterone antagonist therapy and risks of mortality and readmission among patients with heart failure and reduced ejection fractionAdrian F Hernandez
Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA
JAMA 308:2097-107. 2012..Aldosterone antagonist therapy for heart failure and reduced ejection fraction has been highly efficacious in randomized trials. However, questions remain regarding the effectiveness and safety of the therapy in clinical practice... - Pharmacologic prophylaxis for venous thromboembolism and 30-day outcomes among older patients hospitalized with heart failure: an analysis from the ADHERE national registry linked to Medicare claimsRobb D Kociol
Duke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA
Clin Cardiol 34:682-8. 2011..Although pharmacologic prophylaxis regimens have reduced VTE risk in medically ill patients, associations with early postdischarge adverse clinical outcomes among patients with heart failure are unknown... - Long-term outcomes and costs of ventricular assist devices among Medicare beneficiariesAdrian F Hernandez
Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
JAMA 300:2398-406. 2008..In 2003, Medicare expanded coverage of ventricular assist devices as destination, or permanent, therapy for end-stage heart failure. Little is known about the long-term outcomes and costs associated with these devices... - Outcomes of Medicare beneficiaries undergoing catheter ablation for atrial fibrillationJonathan P Piccini
Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
Circulation 126:2200-7. 2012..Atrial fibrillation is common among older persons. Catheter ablation is increasingly used in patients for whom medical therapy has failed... - Relationships between emerging measures of heart failure processes of care and clinical outcomesAdrian F Hernandez
Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
Am Heart J 159:406-13. 2010..Previous studies have not confirmed associations between some current performance measures for inpatient heart failure processes of care and postdischarge outcomes. It is unknown if alternative measures are associated with outcomes... - Associations of patient demographic characteristics and regional physician density with early physician follow-up among medicare beneficiaries hospitalized with heart failureRobb D Kociol
Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA
Am J Cardiol 108:985-91. 2011..Strategies are needed to ensure access among vulnerable populations to this supply-sensitive resource... - Design and rationale of a retrospective clinical effectiveness study of aldosterone antagonist therapy in patients with heart failureLesley H Curtis
Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
Am Heart J 163:946-953.e1. 2012..Questions remain about its clinical effectiveness and safety for patients who are underrepresented in randomized trials and those at risk for hyperkalemia... - B-type natriuretic peptide level and postdischarge thrombotic events in older patients hospitalized with heart failure: insights from the Acute Decompensated Heart Failure National RegistryRobb D Kociol
Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
Am Heart J 163:994-1001. 2012..Associations between BNP level and thromboembolic events in patients with HF without atrial fibrillation (AF) are not well studied... - Representativeness of a national heart failure quality-of-care registry: comparison of OPTIMIZE-HF and non-OPTIMIZE-HF Medicare patientsLesley H Curtis
Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
Circ Cardiovasc Qual Outcomes 2:377-84. 2009..Participation in clinical registries is nonrandom, so participants may differ in important ways from nonparticipants. The extent to which findings from clinical registries can be generalized to broader populations is unclear... 
Patient-reported frequency of taking aspirin in a population with coronary artery diseaseNancy M Allen LaPointe
Duke CERTs Centers for Education and Research on Therapeutics at the Duke Clinical Research Institute, Durham, North Carolina 27715, USA
Am J Cardiol 89:1042-6. 2002..Although the rate of aspirin use in this population was higher than previously reported, an estimated 6% of eligible patients were not receiving antiplatelet therapy...- National survey of hospital strategies to reduce heart failure readmissions: findings from the Get With the Guidelines-Heart Failure registryRobb D Kociol
Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
Circ Heart Fail 5:680-7. 2012..Reducing 30-day heart failure readmission rates is a national priority. Yet, little is known about how hospitals address the problem and whether hospital-based processes of care are associated with reductions in readmission rates... - Treatment patterns for neovascular age-related macular degeneration: analysis of 284 380 medicare beneficiariesLesley H Curtis
Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
Am J Ophthalmol 153:1116-24.e1. 2012..To examine trends in the treatment of newly diagnosed neovascular age-related macular degeneration (AMD)... - Predicting costs among medicare beneficiaries with heart failureMelissa A Greiner
Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA
Am J Cardiol 109:705-11. 2012..In conclusion, a model based on variables from clinical registries can identify a group of patients with heart failure who on average will incur higher costs in the first year after hospitalization... - Clinical effectiveness of implantable cardioverter-defibrillators among medicare beneficiaries with heart failureAdrian F Hernandez
Duke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, NC, USA
Circ Heart Fail 3:7-13. 2010..The clinical effectiveness of implantable cardioverter-defibrillators (ICDs) in older patients with heart failure has not been established, and older patients have been underrepresented in previous studies... - Clopidogrel use and clinical events after drug-eluting stent implantation: findings from the HealthCore Integrated Research DatabaseJohn L Petersen
Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
Am Heart J 159:462-470.e1. 2010..Relationships between long-term use and level of dual antiplatelet therapy and outcomes after drug-eluting stent implantation are not well established... - Long-term outcomes of medicare beneficiaries with worsening renal function during hospitalization for heart failureRobb D Kociol
Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
Am J Cardiol 105:1786-93. 2010..12, 95% confidence interval 1.04 to 1.20) but not readmission or total inpatient costs. In conclusion, worsening RF in patients hospitalized with HF was independently associated with long-term mortality... - Association between the Medicare Modernization Act of 2003 and patient wait times and travel distance for chemotherapyAlisa M Shea
Center for Clinical and Genetic Economics, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
JAMA 300:189-96. 2008..Anecdotal reports suggest that these adjustments may have negatively affected access to chemotherapy for Medicare beneficiaries... - Relationship between early physician follow-up and 30-day readmission among Medicare beneficiaries hospitalized for heart failureAdrian F Hernandez
Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
JAMA 303:1716-22. 2010..However, there are limited data describing patterns of follow-up after heart failure hospitalization and its association with readmission rates... - Linking inpatient clinical registry data to Medicare claims data using indirect identifiersBradley G Hammill
Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
Am Heart J 157:995-1000. 2009..We present a method to link hospitalization records from registries with Medicare inpatient claims data, without using direct identifiers, to create a unique data source that pairs rich clinical data with long-term outcome data... - Predicting long-term mortality in older patients after non-ST-segment elevation myocardial infarction: the CRUSADE long-term mortality model and risk scoreMatthew T Roe
Duke Clinical Research Institute, Durham, NC, USA
Am Heart J 162:875-883.e1. 2011..We sought to develop a long-term mortality risk prediction model and a simplified risk score for use in older patients with non-ST-segment elevation myocardial infarction (NSTEMI)... - Incidence and prevalence of atrial fibrillation and associated mortality among Medicare beneficiaries, 1993-2007Jonathan P Piccini
Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
Circ Cardiovasc Qual Outcomes 5:85-93. 2012..The frequency of AF increases with age, but representative national data about incidence and prevalence are limited. We examined the annual incidence, prevalence, and mortality associated with AF among older persons... - External validity of the cardiovascular health study: a comparison with the Medicare populationLisa D DiMartino
Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA
Med Care 47:916-23. 2009..The Cardiovascular Health Study (CHS), a population-based prospective cohort study, has been used to identify major risk factors associated with cardiovascular disease and stroke in the elderly... - Generalizability and longitudinal outcomes of a national heart failure clinical registry: Comparison of Acute Decompensated Heart Failure National Registry (ADHERE) and non-ADHERE Medicare beneficiariesRobb D Kociol
Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
Am Heart J 160:885-92. 2010..Clinical registries are used increasingly to analyze quality and outcomes, but the generalizability of findings from registries is unclear... - Changes in the use and costs of diagnostic imaging among Medicare beneficiaries with cancer, 1999-2006Michaela A Dinan
Center for Clinical and Genetic Economics, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
JAMA 303:1625-31. 2010..Imaging is the fastest growing expense for Medicare but has not been examined among beneficiaries with cancer... - Process of care performance measures and long-term outcomes in patients hospitalized with heart failureMark E Patterson
Center for Clinical and Genetic Economics, Duke University School of Medicine, Durham, NC, USA
Med Care 48:210-6. 2010..Recent efforts to improve care for patients hospitalized with heart failure have focused on process-based performance measures. Data supporting the link between current process measures and patient outcomes are sparse... - Resource use and costs of branch and central retinal vein occlusion in the elderlySharon Fekrat
Duke University School of Medicine, Durham, NC, USA 27715
Curr Med Res Opin 26:223-30. 2010..To examine the incidence, prevalence, resource use, and costs associated with branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO) in elderly patients... - Incidence and prevalence of heart failure in elderly persons, 1994-2003Lesley H Curtis
Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Durham, NC 27715, USA
Arch Intern Med 168:418-24. 2008..We sought to estimate the annual incidence and prevalence of heart failure and associated survival in elderly persons from January 1, 1994, through December 31, 2003... - Clinical effectiveness of beta-blockers in heart failure: findings from the OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure) RegistryAdrian F Hernandez
Duke Clinical Research Institute, Durham, NC 27715, USA
J Am Coll Cardiol 53:184-92. 2009..We sought to examine associations between initiation of beta-blocker therapy and outcomes among elderly patients hospitalized for heart failure... - Assessment of left ventricular function in older Medicare beneficiaries with newly diagnosed heart failureLesley H Curtis
Duke Clinical Research Institute and Department of Medicine, Duke University School of Medicine, Durham, NC 27715, USA
Circ Cardiovasc Qual Outcomes 4:85-91. 2011..Little is known about the extent to which left ventricular function is assessed in real-world settings... - Risks of mortality, myocardial infarction, bleeding, and stroke associated with therapies for age-related macular degenerationLesley H Curtis
Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA
Arch Ophthalmol 128:1273-9. 2010..To examine associations between therapies for age-related macular degeneration and risks of all-cause mortality, incident myocardial infarction, bleeding, and incident stroke... - Pancreatic beta-cell function as a predictor of cardiovascular outcomes and costs: findings from the Cardiovascular Health StudyLesley H Curtis
Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
Curr Med Res Opin 24:41-50. 2008..To explore relationships between beta-cell function and incident cardiovascular events, death, and medical costs among elderly individuals... - Long-term adherence to evidence-based secondary prevention therapies in coronary artery diseaseL Kristin Newby
Centers for Education and Research on Therapeutics, Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
Circulation 113:203-12. 2006..Studies have examined the use of evidence-based therapies for coronary artery disease (CAD) in the short term and at hospital discharge, but few have evaluated long-term use... - Sex differences in the use of implantable cardioverter-defibrillators for primary and secondary prevention of sudden cardiac deathLesley H Curtis
Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA
JAMA 298:1517-24. 2007..Previous studies of sex differences in the use of implantable cardioverter-defibrillators (ICDs) predate recent expansions in Medicare coverage and did not provide patient follow-up over multiple years... - Multifaceted intervention to promote beta-blocker use in heart failureNancy M Allen LaPointe
Center for Education and Research on Therapeutics, Duke Clinical Research Institute, Durham, NC 27715, USA
Am Heart J 151:992-8. 2006..Despite a survival benefit and guideline recommendation for beta-blockers in left ventricular systolic dysfunction, beta-blockers are underused in clinical practice... - Early and long-term outcomes of heart failure in elderly persons, 2001-2005Lesley H Curtis
Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Durham, NC 27715, USA
Arch Intern Med 168:2481-8. 2008..The treatment of chronic heart failure has improved during the past 2 decades, but little is known about whether the improvements are reflected in trends in early and long-term mortality and hospital readmission... - Costs of newly diagnosed neovascular age-related macular degeneration among medicare beneficiaries, 2004-2008Laura G Qualls
Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina Global Health Outcomes, GlaxoSmithKline, Inc, Philadelphia, Pennsylvania Departments of Ophthalmology, and Medicine, Duke University School of Medicine, Durham, North Carolina
Retina 33:854-61. 2013..To examine associations between newly diagnosed neovascular age-related macular degeneration and direct medical costs... - Using inverse probability-weighted estimators in comparative effectiveness analyses with observational databasesLesley H Curtis
Duke Clinical Research Institute, and Departments of Medicine, Duke University School of Medicine, Durham, North Carolina, USA
Med Care 45:S103-7. 2007..Finally, we offer detailed guidance about how to implement the estimators in comparative effectiveness analyses... - Impact of heart failure on patients undergoing major noncardiac surgeryBradley G Hammill
Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Durham, North Carolina, USA
Anesthesiology 108:559-67. 2008..The authors evaluated short-term outcomes among patients with heart failure, coronary artery disease (CAD), or neither who underwent major noncardiac surgery... - A survey of health care practitioners' knowledge of the QT intervalSana M Al-Khatib
Duke Center for Education and Research on Therapeutics, Duke Clinical Research Institute, Durham, NC 27715, USA
J Gen Intern Med 20:392-6. 2005..To assess health care practitioners' ability to correctly measure the QT interval, and to identify factors and medications that may increase the risk of QT-interval prolongation and torsades de pointes... - Medical costs of abnormal serum sodium levelsAlisa M Shea
Center for Clinical and Genetic Economics, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
J Am Soc Nephrol 19:764-70. 2008..2%). Costs associated with hypernatremia were not significantly different from those incurred by patients with normal serum sodium. In conclusion, hyponatremia is a significant independent predictor of 6-mo and 1-yr direct medical costs... - A decade of short-term outcomes in post cardiac surgery ventricular assist device implantation: data from the Society of Thoracic Surgeons' National Cardiac DatabaseAdrian F Hernandez
Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
Circulation 116:606-12. 2007..We examined a large national clinical database to assess trends in the incidence of post-cardiac surgery shock requiring VAD implantation, survival rates, and risk factors for mortality... - Resource use and costs associated with diabetic macular edema in elderly personsAlisa M Shea
Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Durham, NC 27715, USA
Arch Ophthalmol 126:1748-54. 2008..To examine trends in resource use and the effect of incident diabetic macular edema (DME) on 1- and 3-year total direct medical costs in elderly patients... - Physiological and psychosocial factors that predict HIV-related fatigueJulie Barroso
School of Nursing, Duke University, DUMC 3322, Durham, NC 27710, USA
AIDS Behav 14:1415-27. 2010..Physiological variables did not predict greater fatigue. Stressful life events had both direct and indirect effects on fatigue... - Use of patient-reported outcomes in randomized, double-blind, placebo-controlled clinical trialsMichaela A Dinan
Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
Med Care 49:415-9. 2011.... - Costs of the metabolic syndrome in elderly individuals: findings from the Cardiovascular Health StudyLesley H Curtis
Center for Clinical and Genetic Economics, Duke Clinical Research Institute, P O Box 17969, Durham, NC 27715, USA
Diabetes Care 30:2553-8. 2007..Little is known about how the metabolic syndrome and its individual components translate into long-term medical costs... - Outcomes of inpatients with and without sickle cell disease after high-volume surgical proceduresMichaela A Dinan
Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA
Am J Hematol 84:703-9. 2009..Patients with SCD who underwent cholecystectomy or hip replacement required more health care resources than patients without SCD. Am. J. Hematol. 2009. (c) 2009 Wiley-Liss, Inc... - The Medicare Modernization Act and reimbursement for outpatient chemotherapy: do patients perceive changes in access to care?Joeëlle Y Friedman
Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Durham, North Carolina 27715, USA
Cancer 110:2304-12. 2007.... - Implementation of automated reporting of estimated glomerular filtration rate among Veterans Affairs laboratories: a retrospective studyRasheeda K Hall
Center for Health Services Research in Primary Care, Veterans Affairs Health Services Research and Development, Durham, NC, USA
BMC Med Inform Decis Mak 12:69. 2012..This study examines the timing of software implementation by individual VHA laboratories and factors associated with implementation... - Data sources for heart failure comparative effectiveness researchYing Xian
Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
Heart Fail Clin 9:1-13. 2013..Advancing the infrastructure to provide robust, scientific data resources for patient-centered CER must remain a priority... - From controlled trials to clinical practice: monitoring transmyocardial revascularization use and outcomesEric D Peterson
Duke Clinical Research Institute, Durham, North Carolina 27710, USA
J Am Coll Cardiol 42:1611-6. 2003..We also identified important risk factors for TMR and compared outcomes of TMR combined with coronary artery bypass graft surgery (TMR + CABG) versus bypass alone in patients receiving incomplete revascularization... - Underuse of aspirin in a referral population with documented coronary artery diseaseRobert M Califf
Centers for Education and Research on Therapeutics CERTs, Duke Clinical Research Institute, Durham, North Carolina 27715, USA
Am J Cardiol 89:653-61. 2002..The health care system currently lacks effective methods to ensure that patients who have CAD have adequate follow-up concerning aspirin use...