Harold W Goforth
Affiliation: Duke University Medical Center
- The pharmacologic management of insomnia in patients with HIVToma S Omonuwa
Duke University School of Medicine, Durham, NC, USA
J Clin Sleep Med 5:251-62. 2009..The means by which these factors affect the expected risk-benefit profile of insomnia therapies is discussed, and recommendations are made for choosing medications in patients encountered in clinical practice...
- Acute neurologic effects of alcohol and drugsHarold W Goforth
Durham Veterans Affairs Medical Center, 508 Fulton Street, Mailstop 116A, Durham, NC 27705, USA
Neurol Clin 30:277-84, ix. 2012..Neurologic effects of acute drug intoxication are varied. This article discusses the acute neurologic effects of certain drugs as well as associated treatments and guidelines to management...
- Rapid relief of severe major depressive disorder by use of preoperative ketamine and electroconvulsive therapyHarold W Goforth
Duke University Medical Center, and Consultation Liaison Psychiatry Service, Durham Veterans Affairs Medical Center, Durham, NC 27710, USA
J ECT 23:23-5. 2007..This case is supportive of a role of ketamine in relieving symptoms of major depressive disorder rapidly and safely...
- Hydromorphone-OROS formulationHarold W Goforth
Duke University Medical Center, DUMC 3309, Durham, NC 27710, USA
Expert Opin Pharmacother 11:1207-14. 2010..A previous hydromorphone extended-release formulation that successfully came to market was subsequently withdrawn on account of safety concerns. Clinical need supports the presence of an extended-release formulation of hydromorphone...
- Neurologic aspects of drug abuseHarold W Goforth
Duke University Medical Center, Durham, NC 27705, USA
Neurol Clin 28:199-215. 2010..This article also reviews available treatment options for those addicted to substances of abuse, and clarifies common misconceptions, including the differences between tolerance, abuse, and addiction...
- Impact of bereavement on progression of AIDS and HIV infection: a reviewHarold W Goforth
Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, NC 27710, USA
Psychosomatics 50:433-9. 2009..Human immunodeficiency virus (HIV) disease is associated with bereavement and grief reactions brought about by the disease process itself and by the losses of loved ones...
- Low-dose doxepin for the treatment of insomnia: emerging dataHarold W Goforth
Duke University Medical Center and Durham Veterans Affairs Medical Center, Department of Psychiatry, Durham, NC 27705, USA
Expert Opin Pharmacother 10:1649-55. 2009..These properties led to significant dose-limiting side effects, which at times precluded its effective use. Recently, doxepin has seen renewed interest in low doses as an H1 specific antagonist in sleep disorders...
- Comparison of polysomnographic data in age-, sex- and Axis I psychiatric diagnosis matched HIV-seropositive and HIV-seronegative insomnia patientsYinghui Low
Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
Clin Neurophysiol 123:2402-5. 2012..We carried out this study to determine if there are differences in polysomnographic (PSG) sleep data in age-, sex- and Axis I diagnoses- matched HIV-seropositive and HIV-seronegative patients...
- Comorbid HIV encephalopathy and cocaine use as a risk factor for new-onset seizure disordersChristopher A Kenedi
Medicine Psychiatry Program, Duke University Medical Center, Durham, NC 27710, USA
CNS Spectr 13:230-4. 2008..Data from the fields of neuroanatomy and neurovirology are presented to explain the heightened risk of this patient population and provide the practitioner with an improved understanding of the central nervous system complexities in HIV...
- Effects of antipsychotic medications on sleep in schizophreniaAndrew D Krystal
Duke Insomnia and Sleep Research Program, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Int Clin Psychopharmacol 23:150-60. 2008..In this study, we review the effects of schizophrenia medications and discuss their relevance to optimizing the clinical treatment of people with schizophrenia with regard to sleep-wake function...