Kishore M Gadde

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. doi Current pharmacotherapy for obesity: extrapolation of clinical trials data to practice
    Kishore M Gadde
    Duke University Medical Centre, Obesity Clinical Trials Programme, Box 3292, Durham, NC 27710, USA
    Expert Opin Pharmacother 15:809-22. 2014
  2. pmc Zonisamide for weight reduction in obese adults: a 1-year randomized controlled trial
    Kishore M Gadde
    Obesity Clinical Trials Program, Duke University Medical Center, Durham, NC 27710, USA
    Arch Intern Med 172:1557-64. 2012
  3. ncbi Combination therapy of zonisamide and bupropion for weight reduction in obese women: a preliminary, randomized, open-label study
    Kishore M Gadde
    Obesity Clinical Trials Program, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Psychiatry 68:1226-9. 2007
  4. ncbi Cannabinoid-1 receptor antagonist, rimonabant, for management of obesity and related risks
    Kishore M Gadde
    Obesity Clinical Trials Program, Box 3292, Duke University Medical Center, Durham, NC 27710, USA
    Circulation 114:974-84. 2006
  5. ncbi Bupropion for weight reduction
    Kishore M Gadde
    Duke University Medical Centre, Box 3292, Durham, NC 27710, USA
    Expert Rev Neurother 7:17-24. 2007
  6. ncbi Bupropion treatment of olanzapine-associated weight gain: an open-label, prospective trial
    Kishore M Gadde
    Obesity Clinical Trials Programme, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Psychopharmacol 26:409-13. 2006
  7. ncbi Zonisamide for weight loss in obese adults: a randomized controlled trial
    Kishore M Gadde
    Obesity Clinical Trials Program, Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    JAMA 289:1820-5. 2003
  8. ncbi The use of aripiprazole in obsessive-compulsive disorder: preliminary observations in 8 patients
    Kathryn M Connor
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Psychiatry 66:49-51. 2005
  9. ncbi Escitalopram treatment of trichotillomania
    Kishore M Gadde
    Duke University Medical Centre, Durham, NC 27710, USA
    Int Clin Psychopharmacol 22:39-42. 2007
  10. doi Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial
    Kishore M Gadde
    Obesity Clinical Trials Programme, Duke University Medical Center, Durham, NC 27710, USA
    Lancet 377:1341-52. 2011

Detail Information

Publications15

  1. doi Current pharmacotherapy for obesity: extrapolation of clinical trials data to practice
    Kishore M Gadde
    Duke University Medical Centre, Obesity Clinical Trials Programme, Box 3292, Durham, NC 27710, USA
    Expert Opin Pharmacother 15:809-22. 2014
    ..Efficacy is enhanced with combination drug therapies, but so are the hazards. Clinicians should base their decisions on the expected and observed benefit-to-risk balance. ..
  2. pmc Zonisamide for weight reduction in obese adults: a 1-year randomized controlled trial
    Kishore M Gadde
    Obesity Clinical Trials Program, Duke University Medical Center, Durham, NC 27710, USA
    Arch Intern Med 172:1557-64. 2012
    ..We evaluated the efficacy and tolerability of zonisamide, an antiepileptic drug, for enhancing weight loss in obese patients receiving diet and lifestyle guidance...
  3. ncbi Combination therapy of zonisamide and bupropion for weight reduction in obese women: a preliminary, randomized, open-label study
    Kishore M Gadde
    Obesity Clinical Trials Program, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Psychiatry 68:1226-9. 2007
    ..Zonisamide and bupropion have been investigated for weight reduction in obese adults. We conducted a preliminary study comparing the effect on body weight of the combination of these 2 drugs versus zonisamide monotherapy...
  4. ncbi Cannabinoid-1 receptor antagonist, rimonabant, for management of obesity and related risks
    Kishore M Gadde
    Obesity Clinical Trials Program, Box 3292, Duke University Medical Center, Durham, NC 27710, USA
    Circulation 114:974-84. 2006
  5. ncbi Bupropion for weight reduction
    Kishore M Gadde
    Duke University Medical Centre, Box 3292, Durham, NC 27710, USA
    Expert Rev Neurother 7:17-24. 2007
    ....
  6. ncbi Bupropion treatment of olanzapine-associated weight gain: an open-label, prospective trial
    Kishore M Gadde
    Obesity Clinical Trials Programme, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Psychopharmacol 26:409-13. 2006
    ..To examine the effectiveness of bupropion in reducing bodyweight gained during treatment with olanzapine...
  7. ncbi Zonisamide for weight loss in obese adults: a randomized controlled trial
    Kishore M Gadde
    Obesity Clinical Trials Program, Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    JAMA 289:1820-5. 2003
    ..Weight loss was an adverse effect associated with zonisamide treatment in epilepsy clinical trials...
  8. ncbi The use of aripiprazole in obsessive-compulsive disorder: preliminary observations in 8 patients
    Kathryn M Connor
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Psychiatry 66:49-51. 2005
    ..To assess the effectiveness of aripiprazole, an atypical antipsychotic with dopamine- and serotonin-stabilizing properties, as monotherapy in treating obsessive-compulsive disorder (OCD)...
  9. ncbi Escitalopram treatment of trichotillomania
    Kishore M Gadde
    Duke University Medical Centre, Durham, NC 27710, USA
    Int Clin Psychopharmacol 22:39-42. 2007
    ..0001] and for completers [15.8 (1.0)-7.5 (1.2); F=10.1; P<0.0001]. Side effects were mild. Escitalopram treatment for 12 weeks led to significant improvement of trichotillomania in some patients in this small open-label trial...
  10. doi Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial
    Kishore M Gadde
    Obesity Clinical Trials Programme, Duke University Medical Center, Durham, NC 27710, USA
    Lancet 377:1341-52. 2011
    ....
  11. pmc Sexual functioning in obese adults enrolling in a weight loss study
    Truls Ostbye
    Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Sex Marital Ther 37:224-35. 2011
    ..Increasing body mass index was associated with decreasing sexual functioning only for arousal and behavior. Sexual functioning was also reduced on most subscales for individuals who reported sexual inactivity in the past month...
  12. doi Combination therapy for obesity and metabolic disease
    Kishore M Gadde
    Obesity Clinical Trials Programme, Duke University Medical Centre, Durham, North Carolina 27710, USA
    Curr Opin Endocrinol Diabetes Obes 16:353-8. 2009
    ..There is a growing interest in developing combination therapies for treatment and management of obesity and related metabolic diseases...
  13. ncbi Endocannabinoid receptor antagonists and other emerging pharma-cological strategies for weight reduction
    Kishore M Gadde
    Obesity Clinical Trials Programme, Duke University Medical Centre, Durham, NC 27710, USA
    Curr Drug Targets Cardiovasc Haematol Disord 5:549-56. 2005
    ..Recent studies with rimonabant, a cannabinoid type 1 receptor (CB(1)) antagonist, demonstrate clinically significant weight loss as well as reduction in metabolic syndromme burden in obese patients...
  14. ncbi Fluoxetine, comprehensive cognitive behavioral therapy, and placebo in generalized social phobia
    Jonathan R T Davidson
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
    Arch Gen Psychiatry 61:1005-13. 2004
    ..Generalized social phobia is common, persistent, and disabling and is often treated with selective serotonin reuptake inhibitor drugs or cognitive behavioral therapy...
  15. pmc The effect of acute tryptophan depletion on emotional distraction and subsequent memory
    Lihong Wang
    Brain Imaging and Analysis Center, Duke University Medical Center, 2424 Erwin Road, Suite 501 Durham, NC 27705, USA
    Soc Cogn Affect Neurosci 4:357-68. 2009
    ..These findings highlight the importance of serotonin in negative memory with implications for mood disorders...