Jeffrey G Gaca

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. doi request reprint Laser-assisted extraction of pacemaker and defibrillator leads: the role of the cardiac surgeon
    Jeffrey G Gaca
    Division of Cardiothoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ann Thorac Surg 87:1446-50; discussion 1450-1. 2009
  2. ncbi request reprint Prevention of acute lung injury in swine: depletion of pulmonary intravascular macrophages using liposomal clodronate
    Jeffrey G Gaca
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Surg Res 112:19-25. 2003
  3. ncbi request reprint Effect of an anti-C5a monoclonal antibody indicates a prominent role for anaphylatoxin in pulmonary xenograft dysfunction
    Jeffrey G Gaca
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Transplantation 81:1686-94. 2006
  4. ncbi request reprint Depletion of pulmonary intravascular macrophages prevents hyperacute pulmonary xenograft dysfunction
    Edward Cantu
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Transplantation 81:1157-64. 2006
  5. ncbi request reprint Risk-adjusted survival after tissue versus mechanical aortic valve replacement: a 23-year assessment
    Jeffrey G Gaca
    Duke University Medical Center, Durham, NC 27710, USA
    J Heart Valve Dis 22:810-6. 2013
  6. doi request reprint Effects of institutional volumes on operative outcomes for aortic root replacement in North America
    G Chad Hughes
    Society of Thoracic Surgeons Database, Durham, NC, USA
    J Thorac Cardiovasc Surg 145:166-70. 2013
  7. pmc Randomized, double-blinded, placebo controlled study of neuroprotection with lidocaine in cardiac surgery
    Joseph P Mathew
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Stroke 40:880-7. 2009
  8. ncbi request reprint Outcomes of acute type a dissection repair before and after implementation of a multidisciplinary thoracic aortic surgery program
    Nicholas D Andersen
    Department of Surgery, Division of Cardiovascular and Thoracic Surgery, Duke University Medical Center, Durham, North Carolina
    J Am Coll Cardiol 63:1796-803. 2014
  9. ncbi request reprint The role of the porcine von Willebrand factor: baboon platelet interactions in pulmonary xenotransplantation
    Jeffrey G Gaca
    Department of Surgery, Duke University Medical Center, Durham, NC, USA
    Transplantation 74:1596-603. 2002
  10. pmc Predictors of electrocerebral inactivity with deep hypothermia
    Michael L James
    Department of Anesthesiology, Duke University Medical Center, Durham, NC Brain Injury Translational Research Center, Duke University Medical Center, Durham, NC Division of Neurology, Department of Medicine, Duke University Medical Center, Durham, NC
    J Thorac Cardiovasc Surg 147:1002-7. 2014

Collaborators

Detail Information

Publications25

  1. doi request reprint Laser-assisted extraction of pacemaker and defibrillator leads: the role of the cardiac surgeon
    Jeffrey G Gaca
    Division of Cardiothoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ann Thorac Surg 87:1446-50; discussion 1450-1. 2009
    ..9% to 3.4%. The purpose of this study was to determine the rate of major cardiovascular injury and emphasize the need for cardiothoracic surgical participation in this procedure...
  2. ncbi request reprint Prevention of acute lung injury in swine: depletion of pulmonary intravascular macrophages using liposomal clodronate
    Jeffrey G Gaca
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Surg Res 112:19-25. 2003
    ..We used liposomal clodronate to eliminate the PIM population in a model of acute swine lung injury...
  3. ncbi request reprint Effect of an anti-C5a monoclonal antibody indicates a prominent role for anaphylatoxin in pulmonary xenograft dysfunction
    Jeffrey G Gaca
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Transplantation 81:1686-94. 2006
    ..The current study investigates the role of C5a in pulmonary xenograft failure in baboons...
  4. ncbi request reprint Depletion of pulmonary intravascular macrophages prevents hyperacute pulmonary xenograft dysfunction
    Edward Cantu
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Transplantation 81:1157-64. 2006
    ..Recent findings have suggested that donor pulmonary intravascular macrophages may play a critical role in the hyperacute dysfunction of pulmonary xenografts...
  5. ncbi request reprint Risk-adjusted survival after tissue versus mechanical aortic valve replacement: a 23-year assessment
    Jeffrey G Gaca
    Duke University Medical Center, Durham, NC 27710, USA
    J Heart Valve Dis 22:810-6. 2013
    ..The study aim was to test the hypothesis that AVR with tissue valves is associated with a lower risk-adjusted survival, as compared to mechanical valves...
  6. doi request reprint Effects of institutional volumes on operative outcomes for aortic root replacement in North America
    G Chad Hughes
    Society of Thoracic Surgeons Database, Durham, NC, USA
    J Thorac Cardiovasc Surg 145:166-70. 2013
    ..The present study sought to evaluate the relationship between the volume of aortic root replacement procedures and the operative results for centers in North America...
  7. pmc Randomized, double-blinded, placebo controlled study of neuroprotection with lidocaine in cardiac surgery
    Joseph P Mathew
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Stroke 40:880-7. 2009
    ..Based on experimental and clinical evidence, this study assessed the potential of intravenously administered lidocaine to reduce postoperative cognitive dysfunction after cardiac surgery using cardiopulmonary bypass...
  8. ncbi request reprint Outcomes of acute type a dissection repair before and after implementation of a multidisciplinary thoracic aortic surgery program
    Nicholas D Andersen
    Department of Surgery, Division of Cardiovascular and Thoracic Surgery, Duke University Medical Center, Durham, North Carolina
    J Am Coll Cardiol 63:1796-803. 2014
    ....
  9. ncbi request reprint The role of the porcine von Willebrand factor: baboon platelet interactions in pulmonary xenotransplantation
    Jeffrey G Gaca
    Department of Surgery, Duke University Medical Center, Durham, NC, USA
    Transplantation 74:1596-603. 2002
    ....
  10. pmc Predictors of electrocerebral inactivity with deep hypothermia
    Michael L James
    Department of Anesthesiology, Duke University Medical Center, Durham, NC Brain Injury Translational Research Center, Duke University Medical Center, Durham, NC Division of Neurology, Department of Medicine, Duke University Medical Center, Durham, NC
    J Thorac Cardiovasc Surg 147:1002-7. 2014
    ..We sought to determine predictors of ECI to help guide cooling protocols when EEG monitoring is unavailable...
  11. ncbi request reprint Disseminated intravascular coagulation in association with pig-to-primate pulmonary xenotransplantation
    Jeffrey G Gaca
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Transplantation 73:1717-23. 2002
    ..Disseminated intravascular coagulation (DIC) has been observed with the rejection of renal and bone marrow xenografts but has not yet been described in pulmonary xenografts...
  12. ncbi request reprint Non-anti-Gal alpha1-3Gal antibody mechanisms are sufficient to cause hyperacute lung dysfunction in pulmonary xenotransplantation
    Gonzalo V Gonzalez-Stawinski
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    J Am Coll Surg 194:765-73. 2002
    ....
  13. doi request reprint Twenty-five-year outcomes after multiple internal thoracic artery bypass
    Cyrus J Parsa
    Duke University Medical Center, Durham, NC, USA
    J Thorac Cardiovasc Surg 145:970-5. 2013
    ..This study assessed single institutional outcomes with multiple internal thoracic artery grafting for guidance with future clinical decisions...
  14. doi request reprint Frailty and risk in proximal aortic surgery
    Asvin M Ganapathi
    Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC
    J Thorac Cardiovasc Surg 147:186-191.e1. 2014
    ..The objective of the present study was to evaluate the role of frailty in predicting postoperative morbidity and mortality in patients undergoing proximal aortic replacement surgery...
  15. doi request reprint Comparison of attachment site endoleak rates in Dacron versus native aorta landing zones after thoracic endovascular aortic repair
    Asvin M Ganapathi
    Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC
    J Vasc Surg 59:921-9. 2014
    ..However, no study has rigorously examined endoleak rates in Dacron landing zones vs native aorta...
  16. doi request reprint Current outcomes for tricuspid valve infective endocarditis surgery in North America
    Jeffrey G Gaca
    Duke University Medical Center, Durham, North Carolina Electronic address
    Ann Thorac Surg 96:1374-81. 2013
    ..The purpose of this study was to describe the population and outcomes for isolated TV IE using The Society of Thoracic Surgeons Adult Cardiac Database...
  17. ncbi request reprint Aortic valve replacement via right minithoracotomy versus median sternotomy: a propensity score analysis
    Donald D Glower
    From the Department of Surgery, Duke University Medical Center, Durham, NC USA
    Innovations (Phila) 9:75-81; discussion 81. 2014
    ..The aim of this study was to define the relative role of a right minithoracotomy (RT) versus standard median sternotomy (ST) for open aortic valve replacement (AVR)...
  18. doi request reprint Minithoracotomy versus sternotomy for mitral surgery in patients with chronic renal impairment: a propensity-matched study
    Paul Tang
    From the Department of Surgery, and Department of Anesthesia, Duke University Medical Center, Durham, NC USA
    Innovations (Phila) 8:325-31. 2013
    ..Therefore, we examined propensity-matched patients with chronic renal impairment to compare outcomes...
  19. pmc Intraoperative use of low-dose recombinant activated factor VII during thoracic aortic operations
    Nicholas D Andersen
    Department of Surgery, Division of Cardiovascular and Thoracic Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ann Thorac Surg 93:1921-8; discussion 1928-9. 2012
    ..Here we report the novel use of intraoperative low-dose rFVIIa in thoracic aortic operations, a strategy intended to improve safety by minimizing rFVIIa exposure...
  20. doi request reprint Outcomes for endocarditis surgery in North America: a simplified risk scoring system
    Jeffrey G Gaca
    Duke University Medical Center, Durham, NC 27710, USA
    J Thorac Cardiovasc Surg 141:98-106.e1-2. 2011
    ..The Society of Thoracic Surgeons Adult Cardiac Surgery Database was examined to develop a simple risk scoring system and identify areas for quality improvement...
  21. pmc Cognitive function after major noncardiac surgery, apolipoprotein E4 genotype, and biomarkers of brain injury
    David L McDonagh
    Department of Anesthesiology and Medicine, Division of Cardiothoracic Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesthesiology 112:852-9. 2010
    ..Identified risk factors are largely limited to demographic characteristics. We hypothesized that POCD was associated with apolipoprotein E4 (APOE4) genotype and plasma biomarkers of brain injury and inflammation...
  22. ncbi request reprint Pilot study of sternal plating for primary closure of the sternum in cardiac surgical patients
    Elliott Bennett-Guerrero
    From the Duke Clinical Research Institute, Duke University, Durham, NC USA Department of Anesthesiology and Division of Cardiothoracic Surgery, Duke University Medical Center, Durham, NC USA and Oklahoma Heart Institute, Hillcrest Medical Center, Tulsa, OK USA
    Innovations (Phila) 6:382-8. 2011
    ..The rapid sternal closure system (Talon) is approved for stabilization and fixation of the anterior chest wall. Anecdotal evidence suggests that use of the Talon may result in improved postoperative recovery...
  23. pmc Results of proximal arch replacement using deep hypothermia for circulatory arrest: is moderate hypothermia really justifiable?
    Brian Lima
    Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Am Surg 77:1438-44. 2011
    ..Centers using lesser degrees of hypothermia for arch surgery, the safety of which remains unproven, should ensure comparable results...
  24. ncbi request reprint Binding of polyreactive antibodies to self versus foreign antigens
    Winston Lee
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Immunobiology 205:95-107. 2002
    ..These data shed light on the fundamental nature of polyreactive antibodies, and may provide additional insight into their putative biological roles...
  25. pmc Pulse pressure and long-term survival after coronary artery bypass graft surgery
    Nikolay M Nikolov
    Division of Cardiothoracic Anesthesiology and Critical Care Medicine, Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesth Analg 110:335-40. 2010
    ..We therefore assessed long-term survival in patients with increased PP at the time of presentation for CABG surgery...