Rebekah L Fleming

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc Binge-pattern ethanol exposure during adolescence, but not adulthood, causes persistent changes in GABAA receptor-mediated tonic inhibition in dentate granule cells
    Rebekah L Fleming
    Durham Veterans Affairs Medical Center, Durham, NC 27705, USA
    Alcohol Clin Exp Res 37:1154-60. 2013
  2. pmc In the rat, chronic intermittent ethanol exposure during adolescence alters the ethanol sensitivity of tonic inhibition in adulthood
    Rebekah L Fleming
    Durham Veterans Affairs Medical Center, Durham, North Carolina 27705, USA
    Alcohol Clin Exp Res 36:279-85. 2012
  3. ncbi request reprint Magnitude and ethanol sensitivity of tonic GABAA receptor-mediated inhibition in dentate gyrus changes from adolescence to adulthood
    Rebekah L Fleming
    Department of Psychiatry, Duke University Medical Center, Durham, NC, USA
    J Neurophysiol 97:3806-11. 2007
  4. pmc GABA transport modulates the ethanol sensitivity of tonic inhibition in the rat dentate gyrus
    Rebekah L Fleming
    Durham Veterans Affairs Medical Center, Durham, NC 27705, USA
    Alcohol 45:577-83. 2011
  5. pmc Long-term effects of chronic intermittent ethanol exposure in adolescent and adult rats: radial-arm maze performance and operant food reinforced responding
    Mary Louise Risher
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America
    PLoS ONE 8:e62940. 2013
  6. doi request reprint Long-term modulation of A-type K(+) conductances in hippocampal CA1 interneurons in rats after chronic intermittent ethanol exposure during adolescence or adulthood
    Qiang Li
    Durham VA Medical Center, Duke University Medical Center, Durham, North Carolina Department of Psychiatry, Duke University Medical Center, Durham, North Carolina Department of Neurosugery, Duke University Medical Center, Durham, North Carolina
    Alcohol Clin Exp Res 37:2074-85. 2013
  7. ncbi request reprint Ethanol regulation of gamma-aminobutyric acid A receptors: genomic and nongenomic mechanisms
    Sandeep Kumar
    Department of Psychiatry, Center for Alcohol Studies, University of Chapel Hill at North Carolina, CB 7178, Chapel Hill, NC 27599, USA
    Pharmacol Ther 101:211-26. 2004

Collaborators

Detail Information

Publications7

  1. pmc Binge-pattern ethanol exposure during adolescence, but not adulthood, causes persistent changes in GABAA receptor-mediated tonic inhibition in dentate granule cells
    Rebekah L Fleming
    Durham Veterans Affairs Medical Center, Durham, NC 27705, USA
    Alcohol Clin Exp Res 37:1154-60. 2013
    ..However, less is known about the long-term neural consequences of chronic EtOH exposure during adolescence, and most importantly whether adolescence represents a developmental period of enhanced vulnerability to such effects...
  2. pmc In the rat, chronic intermittent ethanol exposure during adolescence alters the ethanol sensitivity of tonic inhibition in adulthood
    Rebekah L Fleming
    Durham Veterans Affairs Medical Center, Durham, North Carolina 27705, USA
    Alcohol Clin Exp Res 36:279-85. 2012
    ..2007). In this study, we determined if CIE during adolescence produced long-lasting changes in this tonic current...
  3. ncbi request reprint Magnitude and ethanol sensitivity of tonic GABAA receptor-mediated inhibition in dentate gyrus changes from adolescence to adulthood
    Rebekah L Fleming
    Department of Psychiatry, Duke University Medical Center, Durham, NC, USA
    J Neurophysiol 97:3806-11. 2007
    ....
  4. pmc GABA transport modulates the ethanol sensitivity of tonic inhibition in the rat dentate gyrus
    Rebekah L Fleming
    Durham Veterans Affairs Medical Center, Durham, NC 27705, USA
    Alcohol 45:577-83. 2011
    ..These findings suggest that regulation of ambient GABA by GABA transporters may contribute to the difference in ethanol sensitivity between adolescents and adults...
  5. pmc Long-term effects of chronic intermittent ethanol exposure in adolescent and adult rats: radial-arm maze performance and operant food reinforced responding
    Mary Louise Risher
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America
    PLoS ONE 8:e62940. 2013
    ....
  6. doi request reprint Long-term modulation of A-type K(+) conductances in hippocampal CA1 interneurons in rats after chronic intermittent ethanol exposure during adolescence or adulthood
    Qiang Li
    Durham VA Medical Center, Duke University Medical Center, Durham, North Carolina Department of Psychiatry, Duke University Medical Center, Durham, North Carolina Department of Neurosugery, Duke University Medical Center, Durham, North Carolina
    Alcohol Clin Exp Res 37:2074-85. 2013
    ..Thus, it represents a previously unexplored cellular mechanism whereby chronic ethanol (EtOH) may alter hippocampal memory-related functioning...
  7. ncbi request reprint Ethanol regulation of gamma-aminobutyric acid A receptors: genomic and nongenomic mechanisms
    Sandeep Kumar
    Department of Psychiatry, Center for Alcohol Studies, University of Chapel Hill at North Carolina, CB 7178, Chapel Hill, NC 27599, USA
    Pharmacol Ther 101:211-26. 2004
    ..In this review, we provide an overview of recent data pertaining to mechanisms that could be responsible for altered properties and expression of GABA(A) receptors following chronic ethanol administration...