Genomes and Genes
Affiliation: Duke University Medical Center
- The role of astrocyte-secreted matricellular proteins in central nervous system development and functionCagla Eroglu
Cell Biology, Duke University Medical Center, 333A Nanaline Duke Bldg, Box 3709, Durham, NC 27710 USA
J Cell Commun Signal 3:167-76. 2009..We will discuss a newly described function for thrombospondins in synapse formation in the CNS in detail, and speculate whether other matricellular proteins could play similar roles in nervous system development and function...
- Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesisCagla Eroglu
Duke University Medical Center, Cell Biology Department, Durham, NC 27710, USA
Cell 139:380-92. 2009..These findings identify alpha2delta-1 as a receptor involved in excitatory synapse formation and suggest that gabapentin may function therapeutically by blocking new synapse formation...
- Regulation of synaptic connectivity by gliaCagla Eroglu
Cell Biology Department, Box 3709, Duke University Medical Center, Durham, North Carolina 27710, USA
Nature 468:223-31. 2010..Understanding how signalling between glia and neurons regulates synaptic development will offer new insight into how the nervous system works and provide new targets for the treatment of neurological diseases...
- Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4Eric J Benner
George and Jean Brumley Neonatal Perinatal Research Institute, Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina 27710, USA
Nature 497:369-73. 2013..Taken together, these findings have important implications for post-injury applications of endogenous and transplanted NSCs in the therapeutic setting, as well as disease states where Thbs family members have important roles...
- Thrombospondins as key regulators of synaptogenesis in the central nervous systemW Christopher Risher
Cell Biology Department, Duke University Medical Center, Durham, NC 27710, United States
Matrix Biol 31:170-7. 2012....
- Look who is weaving the neural web: glial control of synapse formationM McLean Bolton
Department of Cell Biology, Duke University Medical Center, 333A Nanaline Duke Bldg, Box 3709, Durham, NC 27710, United States
Curr Opin Neurobiol 19:491-7. 2009....
- Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARCHakan Kucukdereli
Cell Biology Department, Duke University Medical Center, Durham, NC 27710, USA
Proc Natl Acad Sci U S A 108:E440-9. 2011....