Michael Ehlers

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. Ehlers M. Synapse structure: glutamate receptors connected by the shanks. Curr Biol. 1999;9:R848-50 pubmed
    ..A family of proteins has been identified whose members, the Shanks, physically link two major receptor complexes at excitatory synapses - NMDA receptors and metabotropic glutamate receptors. ..
  2. Ehlers M. Dendrite development: a surprising origin. J Cell Biol. 2005;170:517-9 pubmed
    ..Neurons extend elaborate dendrites studded with spines. Unexpectedly, this cellular sculpting is regulated by the origin recognition complex -- the core machinery for initiating DNA replication. ..
  3. Ehlers M, Heine M, Groc L, Lee M, Choquet D. Diffusional trapping of GluR1 AMPA receptors by input-specific synaptic activity. Neuron. 2007;54:447-60 pubmed
    ..Thus, local activity restricts GluR1 mobility on a submicron scale, defining an input-specific mechanism for regulating AMPA receptor composition and abundance. ..