Research Topics
| MICHAEL DE BELLISSummaryAffiliation: Duke University Medical Center Country: USA Publications
Research Grants
| Collaborators |
Detail Information
Publications
Neurodevelopmental biology associated with childhood sexual abuseMichael D De Bellis
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
J Child Sex Abus 20:548-87. 2011..This article will critically review the psychiatric problems associated with maltreatment and the emerging biologic stress system research with a special emphasis on what is known about victimization by sexual abuse...
Sex differences in brain maturation in maltreatment-related pediatric posttraumatic stress disorderMichael D De Bellis
Healthy Childhood Brain Development and Developmental Traumatology Research Program, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Box 3613, Durham, NC 27710, USA
Neurosci Biobehav Rev 27:103-17. 2003..Recent investigations suggested that pediatric posttraumatic stress disorder (PTSD) is associated with adverse brain development. However, sex differences are poorly understood...- Biologic findings of post-traumatic stress disorder and child maltreatmentMichael D De Bellis
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Box 3613, Durham, NC 27710, USA
Curr Psychiatry Rep 5:108-17. 2003..The following is a brief review of the most recent neurobiologic findings in child maltreatment and related PTSD... - Prefrontal cortex, thalamus, and cerebellar volumes in adolescents and young adults with adolescent-onset alcohol use disorders and comorbid mental disordersMichael D De Bellis
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
Alcohol Clin Exp Res 29:1590-600. 2005.... - Cerebellar volumes in pediatric maltreatment-related posttraumatic stress disorderMichael D De Bellis
Healthy Childhood Brain Development and Developmental Traumatology Research Program, Duke University Medical Center, Durham, North Carolina 27710, USA
Biol Psychiatry 60:697-703. 2006..We investigated the relationship between structural volumes of the cerebellum hemispheres, vermis, brainstem, and clinical variables in pediatric maltreatment-related PTSD... 
Demographic, maltreatment, and neurobiological correlates of PTSD symptoms in children and adolescentsMichael D De Bellis
Department of Psychiatry and Behavioral Sciences, Healthy Childhood Brain Development Developmental Traumatology Research Program, Duke University Medical Center, Durham, NC 27710, USA
J Pediatr Psychol 35:570-7. 2010..To examine the relationships of demographic, maltreatment, neurostructural and neuropsychological measures with total posttraumatic stress disorder (PTSD) symptoms...- Segmented hippocampal volume in children and adolescents with posttraumatic stress disorderLarry A Tupler
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
Biol Psychiatry 59:523-9. 2006..CONCLUSIONS: Future longitudinal studies with trauma control subjects and neuropsychological measures are indicated to further elucidate the relationship between hippocampus and behavioral abnormalities in young PTSD subjects... - Neuropsychological findings in childhood neglect and their relationships to pediatric PTSDMichael D De Bellis
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
J Int Neuropsychol Soc 15:868-78. 2009..Trauma experiences may additionally contribute to subsequent neurodevelopmental risk in neglected children. (JINS, 2009, 15, 868-878.)... - Childhood post-traumatic stress disorder: an overviewMichael D De Bellis
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Box 3613, Durham, NC 27710, USA
Child Adolesc Psychiatr Clin N Am 14:745-72, ix. 2005..The importance of developmental and neurobiologic factors and the uniqueness of these factors to children are emphasized... - Development of emotional facial recognition in late childhood and adolescenceLAURA A THOMAS
Center for Cognitive Neuroscience, Duke University, Durham, NC 27708, USA
Dev Sci 10:547-58. 2007..The results provide evidence for late developmental changes in emotional expression recognition with some specificity in the time course for distinct emotions... - Neural substrates for processing task-irrelevant sad images in adolescentsLihong Wang
Duke UNC Brain Imaging and Analysis Center, Duke University Medical Center, USA
Dev Sci 11:23-32. 2008..The pattern of activation to task-irrelevant emotional distraction suggests a possible immaturity of brain function in cognitive control over emotional distraction in adolescents... - Diffusion tensor measures of the corpus callosum in adolescents with adolescent onset alcohol use disordersMichael D De Bellis
Duke Healthy Childhood Brain Development and Developmental Traumatology Research Program, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Alcohol Clin Exp Res 32:395-404. 2008.... - The psychobiology of neglectMichael D De Bellis
Duke University, USA
Child Maltreat 10:150-72. 2005..The author is comprehensively examining these issues as part of the Federal Child Neglect Consortium... - Neuropsychological function in children with maltreatment-related posttraumatic stress disorderSue R Beers
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PA 15213, USA
Am J Psychiatry 159:483-6. 2002..However, there are few studies of cognitive function in children with PTSD. The goal of the current study was to evaluate cognition in children with PTSD... - Superior temporal gyrus volumes in maltreated children and adolescents with PTSDMichael D De Bellis
University of Pittsburgh Medical Center, Developmental Traumatology Program (Developmental Family Health Clinic and Neuroimaging Laboratory, Western Psychiatric Institute and Clinic, Rm 392, 3811 O'Hara Street, Pittsburgh, PA 15213, USA
Biol Psychiatry 51:544-52. 2002..CONCLUSIONS: These STG findings may suggest developmental alterations in maltreatment-related pediatric PTSD... - Superior temporal gyrus volumes in pediatric generalized anxiety disorderMichael D De Bellis
University of Pittsburgh Medical Center, Developmental Traumatology Program (Developmental Family Health Clinic and Neuroimaging Laboratory, Western Psychiatric Institute and Clinic, Rm 392, 3811 O'Hara Street, Pittsburgh, PA 15213, USA
Biol Psychiatry 51:553-62. 2002..CONCLUSIONS: These data agree with previous work implicating posterior right-hemispheric regions in anxiety disorders and may suggest developmental alterations in pediatric GAD... - Brain structures in pediatric maltreatment-related posttraumatic stress disorder: a sociodemographically matched studyMichael D De Bellis
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pennsylvania, USA
Biol Psychiatry 52:1066-78. 2002..CONCLUSIONS: These data provide further evidence to suggest that maltreatment-related PTSD is associated with adverse brain development. These data also suggest that male children may be more vulnerable to these effects... - Pituitary volumes in pediatric maltreatment-related posttraumatic stress disorderLisa A Thomas
Child and Adolescent Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Biol Psychiatry 55:752-8. 2004..This finding may be associated with stress-related differences in CRH and may be more pronounced in pediatric patients with PTSD comorbid with suicidal ideation... - Outcomes of child abuseSue R Beers
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Neurosurg Clin N Am 13:235-41. 2002..In this vulnerable population, longitudinal assessment well past the period of initial insult is imperative to assess the rate of development of skills, to identify deficient areas, and to plan appropriate interventions... - Physical and sexual abuse, depression and alcohol use disorders in adolescents: onsets and outcomesDuncan B Clark
Department of Psychiatry and Pharmaceutical Sciences, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Drug Alcohol Depend 69:51-60. 2003..These results indicate that MDD among adolescents with AUD may be partly attributable to PS Abuse... - Abuse and ACTH response to corticotropin-releasing factorMichael D De Bellis
Am J Psychiatry 159:157; author reply 157-8;. 2002 - Developmental traumatology: a contributory mechanism for alcohol and substance use disordersMichael D De Bellis
University of Pittsburgh Medical Center, Developmental Traumatology Laboratory, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
Psychoneuroendocrinology 27:155-70. 2002....
Research Grants
- Adolescent Alcohol Abuse, PTSD & Hippocampal DevelopmentMICHAEL DE BELLIS; Fiscal Year: 2003..In addition to examining the differences among these groups, the effects of AUD age of onset, AUD severity, as well as alcohol consumption quantity, frequency, and duration, on adolescent hippocampal development will also be examined. ..
- Posttraumatic Stress Disorder & Childhood Sexual Abuse: PsychobiologyMICHAEL DE BELLIS; Fiscal Year: 2007..We further hypothesize that certain risk factors at Time-01 (e.g. age of onset of abuse, adverse life events, and biological measures) will predict the persistence of PTSD at Time-02. ..
- Pediatric maltreatment-related PTSD: PsychobiologyMICHAEL DE BELLIS; Fiscal Year: 2007..Exploring these biological markers in trauma-focused CBT + Sertraline and CBT + placebo is also proposed. ..
- Frontal function in Adolescent Cannabis Use DisordersMICHAEL DE BELLIS; Fiscal Year: 2007..This proposal has public health significance because we will comprehensively evaluate the effects of marijuana on adolescent brain and cognitive development, an understudied area. ..
- Frontal function in Adolescent Cannabis Use DisordersMICHAEL DE BELLIS; Fiscal Year: 2009..This proposal has public health significance because we will comprehensively evaluate the effects of marijuana on adolescent brain and cognitive development, an understudied area. ..
- CHILD NEGLECT--PSYCHOBIOLOGICAL CONSEQUENCESMICHAEL DE BELLIS; Fiscal Year: 2004..abstract_text> ..
- Diffusion Tensor Imaging in Sexually Abused ChildrenMICHAEL DE BELLIS; Fiscal Year: 2004..The study will enhance our knowledge of neuroanatomical/neuropsychological concomitants of sexual abuse in exchange for additional image analysis. ..
- Prefrontal Function in Adolescent Limited vs Life Course Persistent SUDMichael Damingo De Bellis; Fiscal Year: 2010..Understanding of brain dysfunction of addiction is critical for more effective treatments of adolescent substance abuse. ..