Research Topics
| Jonathan DavidsonSummaryAffiliation: Duke University Medical Center Country: USA Publications
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Publications
Effects of venlafaxine extended release on resilience in posttraumatic stress disorder: an item analysis of the Connor-Davidson Resilience ScaleJonathan Davidson
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Trent Drive, 4th Floor, Room 4082B, Durham, NC 27710, USA
Int Clin Psychopharmacol 23:299-303. 2008..The findings suggest that assessment of treatment response might be enhanced by routine evaluation of resilience...- Major depressive disorder treatment guidelines in America and EuropeJonathan R T Davidson
Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, USA
J Clin Psychiatry 71:e04. 2010.... 
Safety and efficacy of escitalopram in the long-term treatment of generalized anxiety disorderJonathan R T Davidson
Department of Psychiatry and Behavioral Science, Duke University Medical Center, Box 3812, Durham, N C 27710, USA
J Clin Psychiatry 66:1441-6. 2005..Generalized anxiety disorder (GAD) is a chronic disorder that requires long-term treatment. Escitalopram has previously been shown to be effective and well tolerated in the acute treatment of GAD...
An abbreviated version of the Connor-Davidson Resilience Scale (CD-RISC), the CD-RISC2: psychometric properties and applications in psychopharmacological trialsSandeep Vaishnavi
Department of Psychiatry and Behavioral Sciences, Duke Medical Center, Box 3812, Durham, NC 27710, USA
Psychiatry Res 152:293-7. 2007....- Treatment of posttraumatic stress disorder with venlafaxine extended release: a 6-month randomized controlled trialJonathan Davidson
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Arch Gen Psychiatry 63:1158-65. 2006..No large-scale posttraumatic stress disorder drug trials have been conducted to evaluate treatment effects beyond 12 weeks outside of those with selective serotonin reuptake inhibitors... - The impairment of Presidents Pierce and Coolidge after traumatic bereavementJonathan R T Davidson
Department of Psychiatry and Behavioral Sciences at Duke University Medical Center, Durham, NC 22705, USA
Compr Psychiatry 49:413-9. 2008..We conclude that the psychiatric consequences of losing a child can adversely affect heads of government, may cause clinically significant distress, altered behavior, and reduced ability to provide effective leadership... - The efficacy and tolerability of tiagabine in adult patients with post-traumatic stress disorderJonathan R T Davidson
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
J Clin Psychopharmacol 27:85-8. 2007..Tiagabine was not significantly different from placebo in the treatment of symptoms of PTSD. Additional studies are needed to assess the role of drugs that target the gamma-aminobutyric acid system in the treatment of PTSD... - Rudolf Steiner (1861-1925)Jonathan Davidson
Duke University Medical Center, Department of Psychiatry and Behavioral Sciences, Box 3812, Durham, NC 27710
Am J Psychiatry 163:1897. 2006 - Venlafaxine extended release in posttraumatic stress disorder: a sertraline- and placebo-controlled studyJonathan Davidson
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
J Clin Psychopharmacol 26:259-67. 2006..Mean maximum daily doses were 225-mg venlafaxine ER and 151-mg sertraline. Both treatments were generally well tolerated. Study results suggest that venlafaxine ER is effective and well tolerated in the short-term treatment of PTSD... - High-dose sertraline strategy for nonresponders to acute treatment for obsessive-compulsive disorder: a multicenter double-blind trialPhilip T Ninan
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 1841 Clifton Road, Atlanta, GA 30329, USA
J Clin Psychiatry 67:15-22. 2006..To evaluate the efficacy and safety of high-dose sertraline for patients with obsessive-compulsive disorder (OCD) who failed to respond to standard sertraline acute treatment... - Explanatory attributions of anxiety and recovery in a study of kavaKurian C Abraham
Duke University Medical Center, Durham, NC 27710, USA
J Altern Complement Med 10:556-9. 2004..When treating patients, it is important to consider the patient's belief systems regarding the disorder, as well as credibility of treatment... - Obsessive-compulsive disorder in callers to the Anxiety Disorders Association of AmericaRosario B Hidalgo
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA
Ann Clin Psychiatry 18:157-62. 2006..CONCLUSIONS: OCD was fairly prevalent among ADAA callers and presented high levels of comorbidity, impairment, health care utilization and sensitivity to psychotropic side effects... - Resilience as a predictor of treatment response in patients with posttraumatic stress disorder treated with venlafaxine extended release or placeboJonathan Davidson
Duke University Medical Center, Durham, NC, USA
J Psychopharmacol 26:778-83. 2012..Future research may be warranted to explore the relationship between response to active treatment and the spectrum of resiliency... - Mirtazapine vs. placebo in posttraumatic stress disorder: a pilot trialJonathan R T Davidson
Duke University Medical Center, Durham, North Carolina 27710, USA
Biol Psychiatry 53:188-91. 2003..The drug was well tolerated. CONCLUSIONS: Mirtazapine was more effective than placebo on some measures in posttraumatic stress disorder and general anxiety symptoms... - Effects of paroxetine and venlafaxine XR on heart rate variability in depressionJonathan Davidson
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
J Clin Psychopharmacol 25:480-4. 2005..Further comparisons of selective serotonin reuptake inhibitor and serotonin and norepinephrine reuptake inhibitor drugs on HRV are warranted... - Mental illness in U.S. Presidents between 1776 and 1974: a review of biographical sourcesJonathan R T Davidson
Department of Psychiatry, Duke University Medical Center, Durham, North Carolina 27710, USA
J Nerv Ment Dis 194:47-51. 2006..Mental illness in heads of state is a topic deserving further attention. Methodological limitations of using biography to determine psychopathology are discussed... - Three- to four-year follow-up to an open trial of nefazodone for combat-related posttraumatic stress disorderMichael A Hertzberg
Duke University Medical Center, Department of Psychiatry, Durham, North Carolina, USA
Ann Clin Psychiatry 14:215-21. 2002.... - Efficacy and tolerability of duloxetine in elderly patients with generalized anxiety disorder: a pooled analysis of four randomized, double-blind, placebo-controlled studiesJonathan Davidson
Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA
Hum Psychopharmacol 23:519-26. 2008..To assess the efficacy and tolerability of duloxetine in elderly patients with generalized anxiety disorder (GAD)... - Improvement of anger at one week predicts the effects of sertraline and placebo in PTSDJonathan Davidson
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Trent Drive, Yellow Zone, Box 3812, 4th Floor, Room 4082B, Durham, NC 27710, USA
J Psychiatr Res 38:497-502. 2004..Our findings imply that, for patients similar to those in this study, an increase in anger after one week of treatment might be one factor to consider when making a decision about continuation of the medication... - Ethnic differences in the treatment of depression in patients with ischemic heart diseaseSilvina V Waldman
Duke University Medical Center, Durham, NC 27710, USA
Am Heart J 157:77-83. 2009..The aim of this study is to examine ethnic differences in depressive symptoms and antidepressant treatment in a cohort of patients undergoing diagnostic coronary angiography... - Symptoms of neurasthenia following earthquake trauma: re-examination of a discarded syndromeWei Zhang
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Psychiatry Res 153:171-7. 2007..The meaningful number of subjects meeting criteria for our algorithm of neurasthenia suggests that further study of this syndrome employing exact ICD-10 diagnostic criteria is warranted... - Levetiracetam in social phobia: a placebo controlled pilot studyWei Zhang
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
J Psychopharmacol 19:551-3. 2005..In summary, the results of this study, while negative on the pre-defined measures, suggest promise for LEV as a new treatment of SAD. Further work should be carried out with larger sample sizes and optimal dosing strategies of the drug... - Traumatic events and posttraumatic stress in cross-cultural mission assignmentsFrauke C Schaefer
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
J Trauma Stress 20:529-39. 2007..Factors associated with the severity of posttraumatic stress were depression, functional impairment, subjective severity and number of traumatic events, and the level of resilience... - Multidimensional effects of sertraline in social anxiety disorderKathryn M Connor
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
Depress Anxiety 23:6-10. 2006..Among common physiological symptoms in this population, blushing and palpitations appear more treatment responsive than trembling and sweating to acute treatment with sertraline... - Antidepressant therapy in patients with ischemic heart diseaseWei Jiang
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Am Heart J 150:871-81. 2005.... - Perceived stress in anxiety disorders and the general population: a study of the Sheehan stress vulnerability scaleKathryn M Connor
Anxiety and Traumatic Stress Program, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Psychiatry Res 151:249-54. 2007..Perceptions of vulnerability to the effects of daily stress are considerably greater in anxiety disorders compared to the general population and also differ within the anxiety disorders... - A history of the concept of atypical depressionJonathan R T Davidson
Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
J Clin Psychiatry 68:10-5. 2007..In this "post-MAOI" era, no novel compound or group of drugs has been clearly shown to have good efficacy in atypical depression, leaving the treatment of atypical depression as an unmet need... - Tiagabine for posttraumatic stress disorder: effects of open-label and double-blind discontinuation treatmentKathryn M Connor
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, P O Box 3812, Durham, NC 27710, USA
Psychopharmacology (Berl) 184:21-5. 2006..Preliminary results suggest a potential benefit of agents that enhance gamma-aminobutyric acid (GABA) neurotransmission in treating posttraumatic stress disorder (PTSD)... - The use of prazosin for the treatment of trauma nightmares and sleep disturbance in combat veterans with post-traumatic stress disorderAndrew D Krystal
Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, USA
Biol Psychiatry 61:925-7. 2007 - Pharmacotherapy of social anxiety disorder: what does the evidence tell us?Jonathan R T Davidson
Department of Psychiatry and Behavioral Science and the Anxiety and Traumatic Stress Program, Duke University Medical Center, Durham, NC 27710, USA
J Clin Psychiatry 67:20-6. 2006..Studies show that patients with SAD who are maintained on paroxetine, sertraline, or clonazepam have a low relapse rate... - Augmentation of sertraline with prolonged exposure in the treatment of posttraumatic stress disorderBarbara O Rothbaum
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30329, USA
J Trauma Stress 19:625-38. 2006..Participants who received PE showed further reduction in PTSD severity. This augmentation effect was observed only for participants who showed a partial response to medication... - Practical assessment and evaluation of mental health problems following a mass disasterKathryn M Connor
Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, NC 27710, USA
J Clin Psychiatry 67:26-33. 2006..The article also addresses important aspects of training nonmedical personnel in screening and assessment... - Botulinum toxin treatment of social anxiety disorder with hyperhidrosis: a placebo-controlled double-blind trialKathryn M Connor
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, DUMC Box 3812, Durham, N C 27710, USA
J Clin Psychiatry 67:30-6. 2006..Given the often prominent and persistent nature of hyperhidrosis in social anxiety disorder (SAD), to compare botulinum toxin type A to placebo for generalized SAD with hyperhidrosis, in combination with paroxetine... - Phobic anxiety, depression, and risk of ventricular arrhythmias in patients with coronary heart diseaseLana L Watkins
Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC 27710, USA
Psychosom Med 68:651-6. 2006..The purpose of this study was to examine whether phobic anxiety is associated with ventricular arrhythmias in patients with documented coronary artery disease (CAD)... - Kava in generalized anxiety disorder: three placebo-controlled trialsKathryn M Connor
Duke University Medical Center, Durham, North Carolina 27710, USA
Int Clin Psychopharmacol 21:249-53. 2006..No evidence of hepatotoxicity was found with kava, and all of the treatments were well tolerated. Findings from these three controlled trials do not support the use of kava in DSM-IV generalized anxiety disorder... - Foreword. After the tsunami: mental health challenges to the community for today and tomorrowJonathan R T Davidson
Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, NC 27710, USA
J Clin Psychiatry 67:3-8. 2006 - The extent and impact of mental health problems after disasterJonathan R T Davidson
Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, NC 27710, USA, and the University of Adelaide, Department of Psychiatry, Queen Elizabeth Hospital, Woodville, Australia
J Clin Psychiatry 67:9-14. 2006..To be effective when disaster occurs, this approach requires careful planning in conjunction with community consultation before implementation of formal disaster mitigation policies... - Pharmacologic treatment of acute and chronic stress following trauma: 2006Jonathan R T Davidson
Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, NC 27710, USA
J Clin Psychiatry 67:34-9. 2006..Dosing strategies for the SSRIs sertraline and paroxetine are provided, and an algorithm for PTSD pharmacotherapy is discussed... - Phobic anxiety and increased risk of mortality in coronary heart diseaseLana L Watkins
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Psychosom Med 72:664-71. 2010..Previous findings suggest that phobic anxiety may pose increased risk of cardiac mortality in medically healthy cohorts... - Remission in post-traumatic stress disorder (PTSD): effects of sertraline as assessed by the Davidson Trauma Scale, Clinical Global Impressions and the Clinician-Administered PTSD scaleJonathan R T Davidson
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA
Int Clin Psychopharmacol 19:85-7. 2004..1-26.3% for sertraline and 13.9-14.9% for placebo. Traditional thresholds for the CAPS and DTS were tested relative to the CGI and to each other. The CAPS and DTS thresholds of < 20 and < 18 were found to be valid... - Posttraumatic stress disorder in callers to the Anxiety Disorders Association of AmericaWei Zhang
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
Depress Anxiety 19:96-104. 2004..In conclusion, callers to ADAA with PTSD were particularly impaired and used the health care system extensively. Although the SPTSD subjects were not as impaired as those with PTSD, they were disadvantaged in many ways... - The impact of borderline personality disorder on post-traumatic stress in the community: a study of health status, health utilization, and functioningKathryn M Connor
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Box 3812, Durham, NC 27710, USA
Compr Psychiatry 43:41-8. 2002..Individuals with comorbid PTSS and BPD demonstrate greater overall impairment and usage of health care resources... - Long-term treatment and prevention of posttraumatic stress disorderJonathan R T Davidson
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
J Clin Psychiatry 65:44-8. 2004..Unanswered questions pertaining to duration of treatment, candidates for long-term treatment, and potentially harmful treatments will also be considered... - Spirituality, resilience, and anger in survivors of violent trauma: a community surveyKathryn M Connor
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
J Trauma Stress 16:487-94. 2003..Forgiveness, hatred, and beliefs in reincarnation were not associated with outcome. The importance of these findings to treating trauma survivors is discussed... - Treatment of posttraumatic stress disorder: the impact of paroxetineJonathan R T Davidson
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Psychopharmacol Bull 37:76-88. 2003..Emerging evidence also suggests that long-term treatment with paroxetine reverses the reductions in hippocampal volume and hypothalamic-pituitary-adrenal axis abnormalities associated with PTSD... - Development of a new resilience scale: the Connor-Davidson Resilience Scale (CD-RISC)Kathryn M Connor
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
Depress Anxiety 18:76-82. 2003..The scale demonstrates that resilience is modifiable and can improve with treatment, with greater improvement corresponding to higher levels of global improvement... - Effectiveness of chromium in atypical depression: a placebo-controlled trialJonathan R T Davidson
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
Biol Psychiatry 53:261-4. 2003..CONCLUSIONS: Chromium picolinate shows promising antidepressant effects in atypical depression. Its mechanism of action may relate to 5HT2A downregulation, increased insulin sensitivity, or to other effects... - Hyperhidrosis in social anxiety disorderJonathan R T Davidson
Duke University Medical Center, Trent Drive, 4th Floor, Yellow Zone, Room 4082B, Box 3812, Durham, NC 27710, USA
Prog Neuropsychopharmacol Biol Psychiatry 26:1327-31. 2002.... - Achieving remission with venlafaxine and fluoxetine in major depression: its relationship to anxiety symptomsJonathan R T Davidson
Department of Psychology Behavioral Sciences, Anxiety and Traumatic Stress Program, Duke University Medicine Center, Durham, North Carolina 27710, USA
Depress Anxiety 16:4-13. 2002.... - Davidson Trauma Scale (DTS): normative scores in the general population and effect sizes in placebo-controlled SSRI trialsJonathan R T Davidson
Anxiety and Traumatic Stress Program, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA
Depress Anxiety 15:75-8. 2002..These results further affirm the utility of the DTS as a self-rating measure of PTSD symptom severity and in evaluating treatment response... - Use of benzodiazepines in social anxiety disorder, generalized anxiety disorder, and posttraumatic stress disorderJonathan R T Davidson
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center South, Durham, NC 27710, USA
J Clin Psychiatry 65:29-33. 2004..Also, research indicates that benzodiazepines may not be effective in the treatment of posttraumatic stress disorder. Therefore, physicians need to consider the type of anxiety disorder before prescribing a benzodiazepine as a treatment... - Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: a double-blind placebo-controlled trialJonathan R T Davidson
Department of Psychiatry, Duke University Medical School, Durham, NC 27710, USA
Eur Neuropsychopharmacol 18:673-81. 2008..8%) than duloxetine-treated patients (13.7%, N=204, P<or=0.001) and worsened on each outcome measure (P<or=0.001, all comparisons). Duloxetine 60-120 mg/day treatment was efficacious and reduced risk of relapse in patients with GAD... - Maintenance therapy with fluoxetine in posttraumatic stress disorder: a placebo-controlled discontinuation studyJonathan R T Davidson
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
J Clin Psychopharmacol 25:166-9. 2005..02, log-rank statistic). The odds ratio for relapse on PBO relative to FLU was 3.50. No significant differences were found on other measures. Fluoxetine was well tolerated during double-blind treatment... - Beliefs in karma and reincarnation among survivors of violent trauma--a community surveyJonathan R T Davidson
Dept of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham NC 27710, USA
Soc Psychiatry Psychiatr Epidemiol 40:120-5. 2005..This survey was designed to examine beliefs in karma and reincarnation among survivors of violent trauma in the general US population... - Quetiapine as monotherapy for social anxiety disorder: a placebo-controlled studySandeep Vaishnavi
Duke University Medical Center, Department of Psychiatry, Room 4082A, Duke South, Yellow Zone, Durham, NC 27710, USA
Prog Neuropsychopharmacol Biol Psychiatry 31:1464-9. 2007..Significant time effects were noted for the SPIN and SDI, as well as a significant time x treatment effect in favor of quetiapine on the SPIN. Additionally, quetiapine showed a large effect size on the SPIN... - Trauma and posttraumatic stress in users of the Anxiety Disorders Association of America Web sitePeter J Nicholls
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Compr Psychiatry 47:30-4. 2006..Furthermore, the factors associated with PTSD were like those in many community surveys. The ADAA Web site has the opportunity to benefit large numbers of highly distressed individuals... - The use of aripiprazole in obsessive-compulsive disorder: preliminary observations in 8 patientsKathryn M Connor
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
J Clin Psychiatry 66:49-51. 2005..To assess the effectiveness of aripiprazole, an atypical antipsychotic with dopamine- and serotonin-stabilizing properties, as monotherapy in treating obsessive-compulsive disorder (OCD)... - Trauma, resilience and saliostasis: effects of treatment in post-traumatic stress disorderJonathan R T Davidson
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
Int Clin Psychopharmacol 20:43-8. 2005..Treatment of PTSD significantly improved resilience and reduced symptoms in this sample. Further controlled studies are indicated... - A double-blind combination study of clonazepam with sertraline in obsessive-compulsive disorderBarbara A Crockett
Department of Psychiatry, Duke University Medical Center, Box 3516, Durham, NC, 27710, USA
Ann Clin Psychiatry 16:127-32. 2004..The determination of efficacy was based primarily on changes from baseline to the last observation taken through week 12. Analysis revealed no significant difference between groups at endpoint on the main scale... - Social anxiety disorder in callers to the Anxiety Disorders Association of AmericaWei Zhang
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
Depress Anxiety 20:101-6. 2004..Early diagnosis and better treatment are urged for reducing costs and improving life. An organization such as ADAA can play a vital role in bringing this about... - Fluoxetine, comprehensive cognitive behavioral therapy, and placebo in generalized social phobiaJonathan R T Davidson
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Arch Gen Psychiatry 61:1005-13. 2004..Generalized social phobia is common, persistent, and disabling and is often treated with selective serotonin reuptake inhibitor drugs or cognitive behavioral therapy... - Escitalopram in the treatment of generalized anxiety disorder: double-blind, placebo controlled, flexible-dose studyJonathan R T Davidson
Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, NC 27710, USA
Depress Anxiety 19:234-40. 2004..9% vs. 5.1%; P=.27). Escitalopram 10-20 mg/day is effective, safe, and well tolerated in the treatment of patients with GAD... - Posttraumatic stress disorder: acquisition, recognition, course, and treatmentJonathan R T Davidson
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center Durham, NC 27710, USA
J Neuropsychiatry Clin Neurosci 16:135-47. 2004..This paper looks at the course of PTSD, its disabling effect, its recognition and treatment, and considers possible new research directions... - Fluvoxamine-controlled release formulation for the treatment of generalized social anxiety disorderJonathan Davidson
Department of Psychiatry, Duke University Medical Center, Trent Drive, 4th Floor, Room 4082B, Durham, NC 27710, USA
J Clin Psychopharmacol 24:118-25. 2004..We report the results of a multicenter, randomized, placebo-controlled trial comparing the efficacy, safety, and tolerability of fluvoxamine controlled release (CR) to placebo in patients with generalized social anxiety disorder... - Modafinil for atypical depression: effects of open-label and double-blind discontinuation treatmentSandeep Vaishnavi
Duke University Medical Center, Durham, NC 27710, USA
J Clin Psychopharmacol 26:373-8. 2006..92). Modafinil was well tolerated and the drug was associated with significant weight loss compared with placebo (P = 0.01)... - Tolerability of fluoxetine in posttraumatic stress disorderStewart D Barnett
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Prog Neuropsychopharmacol Biol Psychiatry 26:363-7. 2002.... - A history of the concept of atypical depressionJonathan R T Davidson
Department of Psychiatry, Duke University Medical Center, Durham, NC, USA
J Clin Psychiatry 68:e03. 2007..The presentation concludes by differentiating between typical and atypical depression and detailing of some of the clinical characteristics of atypical depression... - Efficacy of olanzapine in social anxiety disorder: a pilot studyStewart D Barnett
Department of Psychiatry and Behavioural Sciences, Duke University Medical Center, DUMC, Durham, NC 27710, USA
J Psychopharmacol 16:365-8. 2002..Olanzapine was superior to placebo on the primary outcome measures in this preliminary study of SAD. Additional studies of olanzapine as a treatment for SAD are warranted... - Nonpharmacologic treatments for depression in patients with coronary heart diseaseHeather S Lett
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
Psychosom Med 67:S58-62. 2005..John's wort (SJW), essential fatty acids (EFAs), S-Adenosylmethionine (SAMe), acupuncture, and chromium picolinate (CP)... - An effect-size analysis of pharmacologic treatments for generalized anxiety disorderRosario B Hidalgo
Anxiety and Traumatic Stress Program, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
J Psychopharmacol 21:864-72. 2007..Medications varied in the magnitude of their ES, ranging from moderate to poor. Adolescents and children showed a much greater ES compared with adults. Subjects taking CAM had worse outcomes than placebo... - A comparison of the SPRINT and CAPS assessment scales for posttraumatic stress disorderSandeep Vaishnavi
Department of Psychiatry, Duke University Medical Center, Durham, North Carolina, 27710, USA
Depress Anxiety 23:437-40. 2006..We found that the SPRINT rating scale performs similarly to the CAPS rating scale in the assessment of PTSD symptom clusters and total scores, and that the SPRINT takes significantly less time to administer than the CAPS... - Consensus statement update on posttraumatic stress disorder from the international consensus group on depression and anxietyJames C Ballenger
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA
J Clin Psychiatry 65:55-62. 2004.... - Neuroactive steroids and suicidality in posttraumatic stress disorderMarian I Butterfield
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham Veterans Affairs Medical Center, Durham, NC 27705, USA
Am J Psychiatry 162:380-2. 2005..6 versus 8.3 ng/ml), an association that persisted after adjustment for age. CONCLUSIONS: These findings suggest that higher DHEA levels may be linked to suicidality in veterans with PTSD and may be associated with the risk of self-harm... - Profiling posttraumatic functional impairmentSonya B Norman
Department of Psychiatry, University of California San Diego, and the VA San Diego Healthcare System, La Jolla, California 92093 0985, USA
J Nerv Ment Dis 195:48-53. 2007..The symptom profile can help identify traumatized individuals who may benefit from treatment but do not necessarily meet criteria for PTSD... - Assessing patient beliefs in a clinical trial of Hypericum perforatum in major depressionCarla M Bann
RTI International, Research Triangle Park, North Carolina 27709 2194, USA
Depress Anxiety 20:114-22. 2004..Future studies should explore whether patient beliefs have an even greater impact when patients are aware of the treatment they are receiving and can determine whether that treatment is consistent with their beliefs... - Differential response to placebo among patients with social phobia, panic disorder, and obsessive-compulsive disorderJonathan D Huppert
Center for Treatment and Study of Anxiety, University of Pennsylvania School of Medicine, 6th Floor, 3535 Market St, Philadelphia, PA 19104, USA
Am J Psychiatry 161:1485-7. 2004..Placebo effects in treatment of three anxiety disorders were compared... - Efficacy of the novel anxiolytic pregabalin in social anxiety disorder: a placebo-controlled, multicenter studyAtul C Pande
Pfizer Global Research and Development, New London, CT 06320, USA
J Clin Psychopharmacol 24:141-9. 2004..Somnolence and dizziness were the most frequently occurring adverse events among patients receiving pregabalin 600 mg/d. In conclusion, pregabalin 600 mg/d was an effective and well-tolerated treatment of social anxiety disorder... - Full and partial PTSD among earthquake survivors in rural TaiwanTe-Jen Lai
Institute of Medicine, Chung Shan Medical University and Department of Psychiatry, Chung Shan Medical Hospital, Taichung, Taiwan
J Psychiatr Res 38:313-22. 2004..In conclusion, PTSD and PTSS are commonly observed following earthquake exposure and are associated with similarly high levels of psychosocial impairment... - Pregabalin in generalized anxiety disorder: a placebo-controlled trialAtul C Pande
Pfizer Global Research and Development, Ann Arbor Laboratories, MI, USA
Am J Psychiatry 160:533-40. 2003..In short-term treatment, pregabalin does not appear to have the withdrawal symptoms associated with the benzodiazepines... - Fluvoxamine treatment in veterans with combat-related post-traumatic stress disorderRodrigo Escalona
Psychiatry Service, VA Medical Center, Albuquerque, New Mexico 87018, USA
Depress Anxiety 15:29-33. 2002..The high attrition rate and lack of a placebo group limits the conclusions of our study. Controlled studies of fluvoxamine in the treatment of PTSD are warranted... - Paroxetine CR augmentation for posttraumatic stress disorder refractory to prolonged exposure therapyNaomi M Simon
Center for Anxiety and Traumatic Stress Disorders, Massachusetts General Hospital, Boston, MA 02114, USA
J Clin Psychiatry 69:400-5. 2008..This study prospectively examines the relative efficacy of augmentation of continued prolonged exposure therapy (PE) with paroxetine CR versus placebo for individuals remaining symptomatic despite a course of PE... - Placebo-controlled trial of risperidone augmentation for selective serotonin reuptake inhibitor-resistant civilian posttraumatic stress disorderBarbara O Rothbaum
Department of Psychiatry, Emory University School of Medicine, Atlanta, GA 30329, USA
J Clin Psychiatry 69:520-5. 2008..The primary objective of this study was to examine risperidone augmentation in civilians with PTSD currently receiving sertraline without an optimal response... - Modification effects of coping on post-traumatic morbidity among earthquake rescuersChia Ming Chang
Department of Psychiatry and Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan
Psychiatry Res 158:164-71. 2008..However, coping strategies do not seem to reduce the influence of such exposure on trauma-related morbidities. This suggests that coping strategies can be used to prevent general psychiatric morbidity but not trauma-related morbidities... - Posttraumatic distress and coping strategies among rescue workers after an earthquakeChia-Ming Chang
Department of Psychiatry and Graduate Institute of Medicine, Chung Shan Medical University, No. 110, Sec 1, Chien Kuo N. Road, Taichung, Taiwan
J Nerv Ment Dis 191:391-8. 2003..Rescue workers with longer job experience were at the highest risk for developing psychiatric and posttraumatic distress... - Divalproex in the treatment of posttraumatic stress disorder: a randomized, double-blind, placebo-controlled trial in a veteran populationLori L Davis
Veterans Affairs Medical Center, Tuscaloosa, AL 35404, USA
J Clin Psychopharmacol 28:84-8. 2008..To evaluate the efficacy of divalproex for the treatment of posttraumatic stress disorder (PTSD) hyperarousal symptom cluster... - Impact of depressive symptoms on the treatment of generalized social anxiety disorderDeborah Roth Ledley
Center for the Treatment and Study of Anxiety, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Depress Anxiety 22:161-7. 2005..Such modifications are likely to be more important when treating patients with SAD and comorbid major depressive disorder... - Evidence-based guidelines for the pharmacological treatment of anxiety disorders: recommendations from the British Association for PsychopharmacologyDavid S Baldwin
Division of Clinical Neurosciences, University of Southampton, Southampton, UK
J Psychopharmacol 19:567-96. 2005..The guidelines cover the diagnosis of anxiety disorders and key steps in clinical management, including acute treatment, relapse prevention and approaches for patients who do not respond to first-line treatments... - Generalized social anxiety disorder and avoidant personality disorder: structural analysis and treatment outcomeJonathan D Huppert
Center for the Treatment and Study of Anxiety, Department of Psychiatry, University of Pennsylvania, School of Medicine, Philadelphia, USA
Depress Anxiety 25:441-8. 2008..APD and GSP remain highly related constructs, and different aspects of these data support and dispute the utility of the diagnosis of APD in GSP. Possible new directions in conceptualizing APD are discussed... - Predictors of posttraumatic outcomes following the 1999 Taiwan earthquakeChia-Ming Chang
Department of Psychiatry and Institute of Medicine, Chung Shan Medical University, Chien Kuo N. Road, Taichung 402, Taiwan
J Nerv Ment Dis 193:40-6. 2005..These variables, particularly female gender, current depression, and impaired well-being, should be considered in assessing earthquake survivors who are at increased risk for developing posttraumatic sequelae... - Quetiapine augmentation of paroxetine CR for the treatment of refractory generalized anxiety disorder: preliminary findingsNaomi M Simon
Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Psychopharmacology (Berl) 197:675-81. 2008..More data are needed to guide "next step" strategies for patients with generalized anxiety disorder (GAD) remaining symptomatic despite initial pharmacotherapy...