Eric M Darling

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint Growth factor impact on articular cartilage subpopulations
    Eric M Darling
    Department of Bioengineering, MS 142, Rice University, P O Box 1892, Houston, TX 77251, USA
    Cell Tissue Res 322:463-73. 2005
  2. ncbi request reprint Retaining zonal chondrocyte phenotype by means of novel growth environments
    Eric M Darling
    Department of Bioengineering, Rice University, Houston, Texas, USA
    Tissue Eng 11:395-403. 2005
  3. ncbi request reprint Zonal and topographical differences in articular cartilage gene expression
    Eric M Darling
    Department of Bioengineering, Rice University, PO Box 1892, Houston, TX 77251 1892, USA
    J Orthop Res 22:1182-7. 2004
  4. ncbi request reprint Biomechanical strategies for articular cartilage regeneration
    Eric M Darling
    Musculoskeletal Bioengineering Laboratory, Department of Bioengineering, Rice University, Houston, Texas 77251, USA
    Ann Biomed Eng 31:1114-24. 2003
  5. ncbi request reprint Rapid phenotypic changes in passaged articular chondrocyte subpopulations
    Eric M Darling
    Department of Bioengineering, Rice University, MS 142, P O Box 1892, Houston, TX 77251, USA
    J Orthop Res 23:425-32. 2005
  6. ncbi request reprint Articular cartilage bioreactors and bioprocesses
    Eric M Darling
    Department of Bioengineering, Rice University, Houston, Texas 77251, USA
    Tissue Eng 9:9-26. 2003
  7. pmc Viscoelastic properties of human mesenchymally-derived stem cells and primary osteoblasts, chondrocytes, and adipocytes
    Eric M Darling
    Department of Surgery, Duke University Medical Center Durham, NC 27710, USA
    J Biomech 41:454-64. 2008

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Growth factor impact on articular cartilage subpopulations
    Eric M Darling
    Department of Bioengineering, MS 142, Rice University, P O Box 1892, Houston, TX 77251, USA
    Cell Tissue Res 322:463-73. 2005
    ..Thus, growth factors elicit different proliferation, gene expression, and biosynthesis responses from zonal chondrocyte subpopulations...
  2. ncbi request reprint Retaining zonal chondrocyte phenotype by means of novel growth environments
    Eric M Darling
    Department of Bioengineering, Rice University, Houston, Texas, USA
    Tissue Eng 11:395-403. 2005
    ..These results indicate that a culture environment using aggrecan as a substratum or agarose as a scaffold is crucial to the development of phenotypically correct articular cartilage...
  3. ncbi request reprint Zonal and topographical differences in articular cartilage gene expression
    Eric M Darling
    Department of Bioengineering, Rice University, PO Box 1892, Houston, TX 77251 1892, USA
    J Orthop Res 22:1182-7. 2004
    ..No significant variations in SZP, type II collagen, or aggrecan were found, which makes the pooling of zonal cells from different regions an acceptable option for tissue engineering studies...
  4. ncbi request reprint Biomechanical strategies for articular cartilage regeneration
    Eric M Darling
    Musculoskeletal Bioengineering Laboratory, Department of Bioengineering, Rice University, Houston, Texas 77251, USA
    Ann Biomed Eng 31:1114-24. 2003
    ..This article focuses on the importance of mechanical forces in tissue engineering of articular cartilage and the growth factors that help stimulate the formation of load-bearing tissue...
  5. ncbi request reprint Rapid phenotypic changes in passaged articular chondrocyte subpopulations
    Eric M Darling
    Department of Bioengineering, Rice University, MS 142, P O Box 1892, Houston, TX 77251, USA
    J Orthop Res 23:425-32. 2005
    ..The results of this study suggest that major problems exist at the front-end of cartilage regeneration efforts...
  6. ncbi request reprint Articular cartilage bioreactors and bioprocesses
    Eric M Darling
    Department of Bioengineering, Rice University, Houston, Texas 77251, USA
    Tissue Eng 9:9-26. 2003
    ..All these forces have been integrated into culturing devices that serve as bioreactors for articular cartilage. The strengths and weaknesses of each device and stimulus are explored, as is the future of cartilage bioreactors...
  7. pmc Viscoelastic properties of human mesenchymally-derived stem cells and primary osteoblasts, chondrocytes, and adipocytes
    Eric M Darling
    Department of Surgery, Duke University Medical Center Durham, NC 27710, USA
    J Biomech 41:454-64. 2008
    ..Furthermore, the identification of mechanical properties distinct to stem cells could result in more successful sorting procedures to enrich multipotent progenitor cell populations...

Research Grants2

  1. Stem cell characterization using atomic force microscopy
    ERIC DARLING; Fiscal Year: 2006
    ..These studies will significantly improve our understanding of the cellular-level changes that occur during the stem cell differentiation process. ..
  2. Adult Stem Cell Enrichment via Biomechanical Characterization
    ERIC DARLING; Fiscal Year: 2007
    ..The entire proposed project will produce significant advances in the areas of mechanotransduction, stem cell biology, and tissue engineering. ..