Lesley H Curtis

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint Prostate specific antigen testing in men older than 75 years in the United States
    Charles D Scales
    Duke Prostate Center, Division of Urology, Department of Surgery and Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Urol 176:511-4. 2006
  2. ncbi request reprint Costs of the metabolic syndrome in elderly individuals: findings from the Cardiovascular Health Study
    Lesley H Curtis
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, P O Box 17969, Durham, NC 27715, USA
    Diabetes Care 30:2553-8. 2007
  3. ncbi request reprint Sex and racial differences in the use of implantable cardioverter-defibrillators among patients hospitalized with heart failure
    Adrian F Hernandez
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA
    JAMA 298:1525-32. 2007
  4. doi request reprint Clinical effectiveness of implantable cardioverter-defibrillators among medicare beneficiaries with heart failure
    Adrian F Hernandez
    Duke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, NC, USA
    Circ Heart Fail 3:7-13. 2010
  5. pmc Use of guideline-recommended therapies for heart failure in the Medicare population
    Lisa D DiMartino
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA
    Clin Cardiol 33:400-5. 2010
  6. pmc Who enrolls in the Medicare Part D prescription drug benefit program? Medication use among patients with heart failure
    Zubin J Eapen
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC
    J Am Heart Assoc 2:e000242. 2013
  7. doi request reprint Transitional adherence and persistence in the use of aldosterone antagonist therapy in patients with heart failure
    Lesley H Curtis
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC Department of Medicine, Duke University School of Medicine, Durham, NC Electronic address
    Am Heart J 165:979-986.e1. 2013
  8. doi request reprint Design and rationale of a retrospective clinical effectiveness study of aldosterone antagonist therapy in patients with heart failure
    Lesley H Curtis
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
    Am Heart J 163:946-953.e1. 2012
  9. doi request reprint Treatment patterns for neovascular age-related macular degeneration: analysis of 284 380 medicare beneficiaries
    Lesley H Curtis
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
    Am J Ophthalmol 153:1116-24.e1. 2012
  10. pmc Toward estimating the impact of changes in immigrants' insurance eligibility on hospital expenditures for uncompensated care
    Liana D Castel
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University Medical Center, PO Box 17969, Durham, NC 27715 USA
    BMC Health Serv Res 3:1. 2003

Detail Information

Publications100

  1. ncbi request reprint Prostate specific antigen testing in men older than 75 years in the United States
    Charles D Scales
    Duke Prostate Center, Division of Urology, Department of Surgery and Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Urol 176:511-4. 2006
    ..We examined physician reported PSA testing in elderly men, and physician and practice characteristics associated with testing...
  2. ncbi request reprint Costs of the metabolic syndrome in elderly individuals: findings from the Cardiovascular Health Study
    Lesley H Curtis
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, P O Box 17969, Durham, NC 27715, USA
    Diabetes Care 30:2553-8. 2007
    ..Little is known about how the metabolic syndrome and its individual components translate into long-term medical costs...
  3. ncbi request reprint Sex and racial differences in the use of implantable cardioverter-defibrillators among patients hospitalized with heart failure
    Adrian F Hernandez
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA
    JAMA 298:1525-32. 2007
    ..The influence of sex and race on ICD use among eligible patients is unknown...
  4. doi request reprint Clinical effectiveness of implantable cardioverter-defibrillators among medicare beneficiaries with heart failure
    Adrian F Hernandez
    Duke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, NC, USA
    Circ Heart Fail 3:7-13. 2010
    ..The clinical effectiveness of implantable cardioverter-defibrillators (ICDs) in older patients with heart failure has not been established, and older patients have been underrepresented in previous studies...
  5. pmc Use of guideline-recommended therapies for heart failure in the Medicare population
    Lisa D DiMartino
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA
    Clin Cardiol 33:400-5. 2010
    ..Most information about the use of guideline-recommended therapies for heart failure reflects what occurred at discharge after an inpatient stay...
  6. pmc Who enrolls in the Medicare Part D prescription drug benefit program? Medication use among patients with heart failure
    Zubin J Eapen
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC
    J Am Heart Assoc 2:e000242. 2013
    ..Dispensing data from Medicare Part D standalone prescription drug plans are now available, but characteristics of enrollees with heart failure have not been well described...
  7. doi request reprint Transitional adherence and persistence in the use of aldosterone antagonist therapy in patients with heart failure
    Lesley H Curtis
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC Department of Medicine, Duke University School of Medicine, Durham, NC Electronic address
    Am Heart J 165:979-986.e1. 2013
    ..Aldosterone antagonist therapy is recommended for selected patients with heart failure and reduced ejection fraction. Adherence to therapy in the transition from hospital to home is not well understood...
  8. doi request reprint Design and rationale of a retrospective clinical effectiveness study of aldosterone antagonist therapy in patients with heart failure
    Lesley H Curtis
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
    Am Heart J 163:946-953.e1. 2012
    ..Questions remain about its clinical effectiveness and safety for patients who are underrepresented in randomized trials and those at risk for hyperkalemia...
  9. doi request reprint Treatment patterns for neovascular age-related macular degeneration: analysis of 284 380 medicare beneficiaries
    Lesley H Curtis
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
    Am J Ophthalmol 153:1116-24.e1. 2012
    ..To examine trends in the treatment of newly diagnosed neovascular age-related macular degeneration (AMD)...
  10. pmc Toward estimating the impact of changes in immigrants' insurance eligibility on hospital expenditures for uncompensated care
    Liana D Castel
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University Medical Center, PO Box 17969, Durham, NC 27715 USA
    BMC Health Serv Res 3:1. 2003
    ..Our goal was to assess the effect of PRWORA on hospital uncompensated care in the United States...
  11. ncbi request reprint Sex differences in the use of implantable cardioverter-defibrillators for primary and secondary prevention of sudden cardiac death
    Lesley H Curtis
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA
    JAMA 298:1517-24. 2007
    ..Previous studies of sex differences in the use of implantable cardioverter-defibrillators (ICDs) predate recent expansions in Medicare coverage and did not provide patient follow-up over multiple years...
  12. pmc Assessment of left ventricular function in older Medicare beneficiaries with newly diagnosed heart failure
    Lesley H Curtis
    Duke Clinical Research Institute and Department of Medicine, Duke University School of Medicine, Durham, NC 27715, USA
    Circ Cardiovasc Qual Outcomes 4:85-91. 2011
    ..Little is known about the extent to which left ventricular function is assessed in real-world settings...
  13. doi request reprint Incidence and prevalence of heart failure in elderly persons, 1994-2003
    Lesley H Curtis
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Durham, NC 27715, USA
    Arch Intern Med 168:418-24. 2008
    ..We sought to estimate the annual incidence and prevalence of heart failure and associated survival in elderly persons from January 1, 1994, through December 31, 2003...
  14. doi request reprint Risks of mortality, myocardial infarction, bleeding, and stroke associated with therapies for age-related macular degeneration
    Lesley H Curtis
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA
    Arch Ophthalmol 128:1273-9. 2010
    ..To examine associations between therapies for age-related macular degeneration and risks of all-cause mortality, incident myocardial infarction, bleeding, and incident stroke...
  15. doi request reprint Geographic variation and trends in carotid imaging among medicare beneficiaries, 2001 to 2006
    Lesley H Curtis
    Duke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, NC, USA
    Circ Cardiovasc Qual Outcomes 3:599-606. 2010
    ..We examined temporal trends and geographic variation in the use of carotid ultrasound, carotid magnetic resonance angiography (MRA), and carotid x-ray angiography...
  16. pmc Early and long-term outcomes of heart failure in elderly persons, 2001-2005
    Lesley H Curtis
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Durham, NC 27715, USA
    Arch Intern Med 168:2481-8. 2008
    ..The treatment of chronic heart failure has improved during the past 2 decades, but little is known about whether the improvements are reflected in trends in early and long-term mortality and hospital readmission...
  17. ncbi request reprint Pancreatic beta-cell function as a predictor of cardiovascular outcomes and costs: findings from the Cardiovascular Health Study
    Lesley H Curtis
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
    Curr Med Res Opin 24:41-50. 2008
    ..To explore relationships between beta-cell function and incident cardiovascular events, death, and medical costs among elderly individuals...
  18. ncbi request reprint The value of patient-reported health status in predicting short-term outcomes after coronary artery bypass graft surgery
    Lesley H Curtis
    Department of Community and Preventive Medicine, University of Rochester School of Medicine, Rochester, New York, USA
    Med Care 40:1090-100. 2002
    ..Patient-reported health status may be an important independent predictor of short-term health outcomes...
  19. ncbi request reprint Using inverse probability-weighted estimators in comparative effectiveness analyses with observational databases
    Lesley H Curtis
    Duke Clinical Research Institute, and Departments of Medicine, Duke University School of Medicine, Durham, North Carolina, USA
    Med Care 45:S103-7. 2007
    ..Finally, we offer detailed guidance about how to implement the estimators in comparative effectiveness analyses...
  20. pmc Outcomes associated with warfarin use in older patients with heart failure and atrial fibrillation and a cardiovascular implantable electronic device: findings from the ADHERE registry linked to Medicare claims
    Paul L Hess
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
    Clin Cardiol 35:649-57. 2012
    ..Warfarin use and associated outcomes in patients with heart failure and atrial fibrillation and a cardiovascular implantable electronic device have not been described previously...
  21. doi request reprint Associations between aldosterone antagonist therapy and risks of mortality and readmission among patients with heart failure and reduced ejection fraction
    Adrian F Hernandez
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA
    JAMA 308:2097-107. 2012
    ..Aldosterone antagonist therapy for heart failure and reduced ejection fraction has been highly efficacious in randomized trials. However, questions remain regarding the effectiveness and safety of the therapy in clinical practice...
  22. ncbi request reprint Trends in the use and outcomes of ventricular assist devices among medicare beneficiaries, 2006 through 2011
    Prateeti Khazanie
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina Department of Medicine, Duke University School of Medicine, Durham, North Carolina
    J Am Coll Cardiol 63:1395-404. 2014
    ..This study sought to examine trends in mortality, readmission, and costs among Medicare beneficiaries receiving ventricular assist devices (VADs) and associations between hospital-level procedure volume and outcomes...
  23. pmc Relationships between emerging measures of heart failure processes of care and clinical outcomes
    Adrian F Hernandez
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
    Am Heart J 159:406-13. 2010
    ..Previous studies have not confirmed associations between some current performance measures for inpatient heart failure processes of care and postdischarge outcomes. It is unknown if alternative measures are associated with outcomes...
  24. doi request reprint Pharmacologic prophylaxis for venous thromboembolism and 30-day outcomes among older patients hospitalized with heart failure: an analysis from the ADHERE national registry linked to Medicare claims
    Robb D Kociol
    Duke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA
    Clin Cardiol 34:682-8. 2011
    ..Although pharmacologic prophylaxis regimens have reduced VTE risk in medically ill patients, associations with early postdischarge adverse clinical outcomes among patients with heart failure are unknown...
  25. doi request reprint Clinical effectiveness of anticoagulation therapy among older patients with heart failure and without atrial fibrillation: findings from the ADHERE registry linked to Medicare claims
    Adrian F Hernandez
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
    J Card Fail 19:401-7. 2013
    ..Patients with heart failure are at higher risk for thromboembolic events, even in the absence of atrial fibrillation, but the effect of anticoagulation therapy on outcomes is uncertain...
  26. ncbi request reprint Atypical antipsychotic drugs and diabetes mellitus in a large outpatient population: a retrospective cohort study
    Truls Østbye
    Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Pharmacoepidemiol Drug Saf 14:407-15. 2005
    ..We sought to compare the incidence of new onset diabetes among patients receiving atypical antipsychotics, traditional antipsychotics or antidepressants...
  27. pmc Atrial fibrillation among Medicare beneficiaries hospitalized with sepsis: incidence and risk factors
    Allan J Walkey
    Pulmonary Center and the Section of Pulmonary and Critical Care Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA
    Am Heart J 165:949-955.e3. 2013
    ..However, the prevalence, incidence, and risk factors associated with AF during the sepsis syndromes are unclear...
  28. pmc Outcomes of Medicare beneficiaries undergoing catheter ablation for atrial fibrillation
    Jonathan P Piccini
    Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    Circulation 126:2200-7. 2012
    ..Atrial fibrillation is common among older persons. Catheter ablation is increasingly used in patients for whom medical therapy has failed...
  29. doi request reprint Association between the Medicare Modernization Act of 2003 and patient wait times and travel distance for chemotherapy
    Alisa M Shea
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    JAMA 300:189-96. 2008
    ..Anecdotal reports suggest that these adjustments may have negatively affected access to chemotherapy for Medicare beneficiaries...
  30. doi request reprint Associations of patient demographic characteristics and regional physician density with early physician follow-up among medicare beneficiaries hospitalized with heart failure
    Robb D Kociol
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA
    Am J Cardiol 108:985-91. 2011
    ..Strategies are needed to ensure access among vulnerable populations to this supply-sensitive resource...
  31. doi request reprint Resource use in the last 6 months of life among medicare beneficiaries with heart failure, 2000-2007
    Kathleen T Unroe
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Arch Intern Med 171:196-203. 2011
    ..Heart failure is a common cause of death among Medicare beneficiaries, but little is known about health care resource use at the end of life...
  32. ncbi request reprint Associations between atrial fibrillation and early outcomes of patients with heart failure and reduced or preserved ejection fraction
    Zubin J Eapen
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC Department of Medicine, Duke University School of Medicine, Durham, NC Electronic address
    Am Heart J 167:369-375.e2. 2014
    ..The relative impact of atrial fibrillation on early outcomes of patients with heart failure with reduced or preserved ejection fraction (EF) is unknown...
  33. doi request reprint QRS duration, bundle-branch block morphology, and outcomes among older patients with heart failure receiving cardiac resynchronization therapy
    Pamela N Peterson
    Division of Cardiology, Department of Medicine, Denver Health Medical Center, Denver, CO 80204, USA
    JAMA 310:617-26. 2013
    ..The benefits of cardiac resynchronization therapy (CRT) in clinical trials were greater among patients with left bundle-branch block (LBBB) or longer QRS duration...
  34. doi request reprint B-type natriuretic peptide level and postdischarge thrombotic events in older patients hospitalized with heart failure: insights from the Acute Decompensated Heart Failure National Registry
    Robb D Kociol
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
    Am Heart J 163:994-1001. 2012
    ..Associations between BNP level and thromboembolic events in patients with HF without atrial fibrillation (AF) are not well studied...
  35. pmc Associations between published quality ratings of skilled nursing facilities and outcomes of medicare beneficiaries with heart failure
    Kathleen T Unroe
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
    J Am Med Dir Assoc 13:188.e1-6. 2012
    ..Our study examined associations between ratings and readmission and mortality among Medicare beneficiaries admitted to a skilled nursing facility with a primary diagnosis of heart failure...
  36. ncbi request reprint Long-term outcomes of medicare beneficiaries with worsening renal function during hospitalization for heart failure
    Robb D Kociol
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
    Am J Cardiol 105:1786-93. 2010
    ..12, 95% confidence interval 1.04 to 1.20) but not readmission or total inpatient costs. In conclusion, worsening RF in patients hospitalized with HF was independently associated with long-term mortality...
  37. ncbi request reprint Association between prophylactic implantable cardioverter-defibrillators and survival in patients with left ventricular ejection fraction between 30% and 35%
    Sana M Al-Khatib
    Duke Clinical Research Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina3Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina
    JAMA 311:2209-15. 2014
    ..Because a large number of ICDs in the United States are implanted in such patients, it is important to study survival associated with this therapy...
  38. doi request reprint Early intravenous heart failure therapy and outcomes among older patients hospitalized for acute decompensated heart failure: findings from the Acute Decompensated Heart Failure Registry Emergency Module (ADHERE-EM)
    Yee Weng Wong
    Duke Clinical Research Institute, Durham, NC 27705, USA
    Am Heart J 166:349-56. 2013
    ..We examined the association between time to first intravenous (IV) heart failure (HF) therapy and patient outcomes...
  39. doi request reprint Variations in use of PET among Medicare beneficiaries with non-small cell lung cancer, 1998-2007
    Michaela A Dinan
    Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    Radiology 267:807-17. 2013
    ..To explore demographic and regional factors associated with the use of positron emission tomography (PET) in patients with non-small cell lung cancer (NSCLC) and to determine whether their associations with PET use has changed over time...
  40. doi request reprint National survey of hospital strategies to reduce heart failure readmissions: findings from the Get With the Guidelines-Heart Failure registry
    Robb D Kociol
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
    Circ Heart Fail 5:680-7. 2012
    ..Reducing 30-day heart failure readmission rates is a national priority. Yet, little is known about how hospitals address the problem and whether hospital-based processes of care are associated with reductions in readmission rates...
  41. pmc Follow-up of patients with new cardiovascular implantable electronic devices: are experts' recommendations implemented in routine clinical practice?
    Sana M Al-Khatib
    Duke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, NC 27715, USA
    Circ Arrhythm Electrophysiol 6:108-16. 2013
    ..A 2008 expert consensus statement outlined the minimum frequency of follow-up of patients with cardiovascular implantable electronic devices (CIEDs)...
  42. pmc Survival of patients receiving a primary prevention implantable cardioverter-defibrillator in clinical practice vs clinical trials
    Sana M Al-Khatib
    Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    JAMA 309:55-62. 2013
    ..Whether the survival of patients who received an ICD in primary prevention clinical trials differs from that of trial-eligible patients receiving a primary prevention ICD in clinical practice is unknown...
  43. pmc Representativeness of a national heart failure quality-of-care registry: comparison of OPTIMIZE-HF and non-OPTIMIZE-HF Medicare patients
    Lesley H Curtis
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
    Circ Cardiovasc Qual Outcomes 2:377-84. 2009
    ..Participation in clinical registries is nonrandom, so participants may differ in important ways from nonparticipants. The extent to which findings from clinical registries can be generalized to broader populations is unclear...
  44. ncbi request reprint Frequency of high-risk use of QT-prolonging medications
    Nancy M Allen LaPointe
    Duke Center for Education and Research on Therapeutics, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Pharmacoepidemiol Drug Saf 15:361-8. 2006
    ..Concurrent use of more than one QT-prolonging drug or a QT-prolonging drug with a drug that alters its pharmacokinetic profile is an important risk factor for adverse outcomes...
  45. doi request reprint Relationship between early physician follow-up and 30-day readmission among Medicare beneficiaries hospitalized for heart failure
    Adrian F Hernandez
    Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    JAMA 303:1716-22. 2010
    ..However, there are limited data describing patterns of follow-up after heart failure hospitalization and its association with readmission rates...
  46. pmc Resource use and costs associated with diabetic macular edema in elderly persons
    Alisa M Shea
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Durham, NC 27715, USA
    Arch Ophthalmol 126:1748-54. 2008
    ..To examine trends in resource use and the effect of incident diabetic macular edema (DME) on 1- and 3-year total direct medical costs in elderly patients...
  47. pmc Predicting costs among medicare beneficiaries with heart failure
    Melissa A Greiner
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA
    Am J Cardiol 109:705-11. 2012
    ..In conclusion, a model based on variables from clinical registries can identify a group of patients with heart failure who on average will incur higher costs in the first year after hospitalization...
  48. doi request reprint Clopidogrel use and clinical events after drug-eluting stent implantation: findings from the HealthCore Integrated Research Database
    John L Petersen
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
    Am Heart J 159:462-470.e1. 2010
    ..Relationships between long-term use and level of dual antiplatelet therapy and outcomes after drug-eluting stent implantation are not well established...
  49. pmc Long-term outcomes and costs of ventricular assist devices among Medicare beneficiaries
    Adrian F Hernandez
    Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    JAMA 300:2398-406. 2008
    ..In 2003, Medicare expanded coverage of ventricular assist devices as destination, or permanent, therapy for end-stage heart failure. Little is known about the long-term outcomes and costs associated with these devices...
  50. ncbi request reprint Prevalence of atypical antipsychotic drug use among commercially insured youths in the United States
    Lesley H Curtis
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Arch Pediatr Adolesc Med 159:362-6. 2005
    ..Use of atypical antipsychotic medications in pediatric populations is increasing. Although previous studies have presented data by age or sex, none has documented sex-specific prevalence by age group...
  51. doi request reprint Costs of newly diagnosed neovascular age-related macular degeneration among medicare beneficiaries, 2004-2008
    Laura G Qualls
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA
    Retina 33:854-61. 2013
    ..To examine associations between newly diagnosed neovascular age-related macular degeneration and direct medical costs...
  52. doi request reprint Incremental value of clinical data beyond claims data in predicting 30-day outcomes after heart failure hospitalization
    Bradley G Hammill
    Duke Clinical Research Institute and Department of Medicine, Duke University School of Medicine, Durham, NC 27715, USA
    Circ Cardiovasc Qual Outcomes 4:60-7. 2011
    ..As clinical data become more readily available, the incremental value of adding clinical data to claims-based models of mortality and readmission is unclear...
  53. pmc Linking inpatient clinical registry data to Medicare claims data using indirect identifiers
    Bradley G Hammill
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
    Am Heart J 157:995-1000. 2009
    ..We present a method to link hospitalization records from registries with Medicare inpatient claims data, without using direct identifiers, to create a unique data source that pairs rich clinical data with long-term outcome data...
  54. doi request reprint Racial differences in hospice use and patterns of care after enrollment in hospice among Medicare beneficiaries with heart failure
    Kathleen T Unroe
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
    Am Heart J 163:987-993.e3. 2012
    ..We examined racial differences in patterns of care and resource use among Medicare beneficiaries with heart failure after enrollment in hospice...
  55. pmc Costs of inpatient care among Medicare beneficiaries with heart failure, 2001 to 2004
    David J Whellan
    Center for Clinical and Genetic Economics, Duke University School of Medicine, Durham, NC, USA
    Circ Cardiovasc Qual Outcomes 3:33-40. 2010
    ..Inpatient care is the primary driver of costs for patients with heart failure. It is unclear whether recent advances in heart failure care have reduced the costs to Medicare for the care of inpatients with heart failure...
  56. ncbi request reprint Inappropriate prescribing for elderly Americans in a large outpatient population
    Lesley H Curtis
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Durham, NC 27715, USA
    Arch Intern Med 164:1621-5. 2004
    ..We sought to determine the extent of potentially inappropriate outpatient prescribing for elderly patients, as defined by the Beers revised list of drugs to be avoided in elderly populations...
  57. pmc Follow-up of patients with new cardiovascular implantable electronic devices: is adherence to the experts' recommendations associated with improved outcomes?
    Paul L Hess
    Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    Heart Rhythm 10:1127-33. 2013
    ..A 2008 expert consensus statement recommended an in-person follow-up visit between 2 and 12 weeks after the placement of a new cardiovascular implantable electronic device (CIED)...
  58. pmc Incidence and prevalence of atrial fibrillation and associated mortality among Medicare beneficiaries, 1993-2007
    Jonathan P Piccini
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA
    Circ Cardiovasc Qual Outcomes 5:85-93. 2012
    ..The frequency of AF increases with age, but representative national data about incidence and prevalence are limited. We examined the annual incidence, prevalence, and mortality associated with AF among older persons...
  59. pmc Non-evidence-based ICD implantations in the United States
    Sana M Al-Khatib
    Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    JAMA 305:43-9. 2011
    ....
  60. ncbi request reprint Geographic variation in carotid revascularization among Medicare beneficiaries, 2003-2006
    Manesh R Patel
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Durham, NC 27715, USA
    Arch Intern Med 170:1218-25. 2010
    ..We examined geographic variation in and predictors of carotid endarterectomy and carotid stenting...
  61. ncbi request reprint Socioeconomic status and outcome following acute myocardial infarction in elderly patients
    Sunil V Rao
    Duke Clinical Research Institute, 2400 Pratt Street, Durham, NC 27715, USA
    Arch Intern Med 164:1128-33. 2004
    ..Whether these disparities account for increased mortality among elderly poor patients is not known...
  62. pmc Relationship between cardiac rehabilitation and long-term risks of death and myocardial infarction among elderly Medicare beneficiaries
    Bradley G Hammill
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    Circulation 121:63-70. 2010
    ..The relationship between the number of sessions attended and long-term outcomes is unknown...
  63. pmc Process of care performance measures and long-term outcomes in patients hospitalized with heart failure
    Mark E Patterson
    Center for Clinical and Genetic Economics, Duke University School of Medicine, Durham, NC, USA
    Med Care 48:210-6. 2010
    ..Recent efforts to improve care for patients hospitalized with heart failure have focused on process-based performance measures. Data supporting the link between current process measures and patient outcomes are sparse...
  64. pmc External validity of the cardiovascular health study: a comparison with the Medicare population
    Lisa D DiMartino
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA
    Med Care 47:916-23. 2009
    ..The Cardiovascular Health Study (CHS), a population-based prospective cohort study, has been used to identify major risk factors associated with cardiovascular disease and stroke in the elderly...
  65. ncbi request reprint Evidence-based therapies and mortality in patients hospitalized in December with acute myocardial infarction
    Trip J Meine
    Duke University Medical Center, Durham, North Carolina, USA
    Ann Intern Med 143:481-5. 2005
    ....
  66. ncbi request reprint The effect of dementia on outcomes and process of care for Medicare beneficiaries admitted with acute myocardial infarction
    Frank A Sloan
    Department of Economics and Clinical Research Institute, Duke University, Durham, North Carolina 27708, USA
    J Am Geriatr Soc 52:173-81. 2004
    ..To determine differences in mortality after admission for acute myocardial infarction (AMI) and in use of noninvasive and invasive treatments for AMI between patients with and without dementia...
  67. pmc Changes in initial treatment for prostate cancer among Medicare beneficiaries, 1999-2007
    Michaela A Dinan
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
    Int J Radiat Oncol Biol Phys 82:e781-6. 2012
    ..We examined changes in the management of patients with prostate cancer in the Medicare population...
  68. pmc Clinical effectiveness of beta-blockers in heart failure: findings from the OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure) Registry
    Adrian F Hernandez
    Duke Clinical Research Institute, Durham, NC 27715, USA
    J Am Coll Cardiol 53:184-92. 2009
    ..We sought to examine associations between initiation of beta-blocker therapy and outcomes among elderly patients hospitalized for heart failure...
  69. pmc Geographic variation in the prescription of schedule II opioid analgesics among outpatients in the United States
    Lesley H Curtis
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, P O Box 17969, Durham, NC 27715, USA
    Health Serv Res 41:837-55. 2006
    ..To measure geographic variation in opioid use in a large, commercially insured, outpatient population in the United States...
  70. ncbi request reprint Prostate cancer in the Baby Boomer generation: results from CaPSURE
    Charles D Scales
    Duke Prostate Center, Division of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Urology 70:1162-7. 2007
    ..We sought to characterize prostate cancer (CaP) presentation among this group, and determine whether treatment patterns differ between Baby Boomers and the preceding generation...
  71. doi request reprint Prostate-specific antigen screening among young men in the United States
    Charles D Scales
    Duke Prostate Center, Division of Urology, Department of Surgery, Duke University School of Medicine, Durham, North Carolina 27710, USA
    Cancer 113:1315-23. 2008
    ..Little is known about the use of PSA testing in these men. To understand policy implications of risk stratification, the authors sought to characterize PSA use among young men...
  72. doi request reprint Generalizability and longitudinal outcomes of a national heart failure clinical registry: Comparison of Acute Decompensated Heart Failure National Registry (ADHERE) and non-ADHERE Medicare beneficiaries
    Robb D Kociol
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
    Am Heart J 160:885-92. 2010
    ..Clinical registries are used increasingly to analyze quality and outcomes, but the generalizability of findings from registries is unclear...
  73. doi request reprint Resource use and costs of branch and central retinal vein occlusion in the elderly
    Sharon Fekrat
    Duke University School of Medicine, Durham, NC, USA 27715
    Curr Med Res Opin 26:223-30. 2010
    ..To examine the incidence, prevalence, resource use, and costs associated with branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO) in elderly patients...
  74. pmc Patient and implanting physician factors associated with mortality and complications after implantable cardioverter-defibrillator implantation, 2002-2005
    Sana M Al-Khatib
    Duke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, NC 27715, USA
    Circ Arrhythm Electrophysiol 1:240-9. 2008
    ..We examined patient and implanting physician factors associated with outcomes of ICD therapy in Medicare beneficiaries from 2002 through 2005...
  75. ncbi request reprint Changing gender prevalence of stone disease
    Charles D Scales
    Comprehensive Kidney Stone Center, Division of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Urol 177:979-82. 2007
    ..We examined changes in the prevalence by gender of inpatient hospital discharges for urinary stone disease...
  76. doi request reprint Changes in the use and costs of diagnostic imaging among Medicare beneficiaries with cancer, 1999-2006
    Michaela A Dinan
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    JAMA 303:1625-31. 2010
    ..Imaging is the fastest growing expense for Medicare but has not been examined among beneficiaries with cancer...
  77. doi request reprint Performance of propensity score methods when comparison groups originate from different data sources
    Bradley G Hammill
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
    Pharmacoepidemiol Drug Saf 21:81-9. 2012
    ..To examine the performance of propensity score-based methods for estimating relative risks when exposed and comparison subjects are selected from different data sources...
  78. doi request reprint Identification of patients with diabetic macular edema from claims data: a validation study
    Srilaxmi Bearelly
    Duke University Eye Center, Durham, NC 27715, USA
    Arch Ophthalmol 126:986-9. 2008
    ....
  79. doi request reprint Assessment of temporal trends in mortality with implementation of a statewide ST-segment elevation myocardial infarction (STEMI) regionalization program
    Seth W Glickman
    Duke Clinical Research Institute, Duke University, Durham, NC, USA
    Ann Emerg Med 59:243-252.e1. 2012
    ..Our objective is to explore temporal trends in STEMI mortality with the implementation of a statewide STEMI regionalization program (Reperfusion of Acute Myocardial Infarction in North Carolina Emergency Departments [RACE])...
  80. pmc Sensitivity of International Classification of Diseases codes for hyponatremia among commercially insured outpatients in the United States
    Alisa M Shea
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, PO Box 17969, Durham, North Carolina, USA
    BMC Nephrol 9:5. 2008
    ....
  81. ncbi request reprint Variations in coronary procedure utilization depending on body mass index
    William S Yancy
    Center for Health Services Research in Primary Care, Veterans Affairs Medical Center, Durham, NC 27705, USA
    Arch Intern Med 165:1381-7. 2005
    ..The relationship between BMI and utilization of diagnostic or therapeutic procedures for coronary heart disease has not been examined...
  82. ncbi request reprint Relationship between body mass index and prostate cancer screening in the United States
    Charles D Scales
    Duke Prostate Center, Division of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Urol 177:493-8. 2007
    ..To our knowledge the relationship between obesity and prostate cancer screening behavior in men 40 or older is unknown. Thus, we examined associations between body mass index and prostate cancer screening behavior...
  83. doi request reprint Do heart failure disease management programs make financial sense under a bundled payment system?
    Zubin J Eapen
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am Heart J 161:916-22. 2011
    ..Whether a bundled payment approach can address the negative financial impact of DM programs is unknown...
  84. doi request reprint Bladder augmentation versus urinary diversion in patients with spina bifida in the United States
    John S Wiener
    Department of Surgery, Duke University School of Medicine, Durham, North Carolina, USA
    J Urol 186:161-5. 2011
    ..Therefore, we characterized the use of bladder augmentation and urinary diversion in patients with spina bifida in a nationally representative, all payer, all ages data set...
  85. pmc Associations between worsening renal function and 30-day outcomes among Medicare beneficiaries hospitalized with heart failure
    Uptal D Patel
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA
    Am Heart J 160:132-138.e1. 2010
    ..We examined associations between WRF and 30-day readmission, mortality, and costs among Medicare beneficiaries hospitalized with heart failure...
  86. doi request reprint Impact of heart failure on patients undergoing major noncardiac surgery
    Bradley G Hammill
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Durham, North Carolina, USA
    Anesthesiology 108:559-67. 2008
    ..The authors evaluated short-term outcomes among patients with heart failure, coronary artery disease (CAD), or neither who underwent major noncardiac surgery...
  87. ncbi request reprint Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients
    Lesley H Curtis
    Center for Clinical and Genetic Economics, Duke University Medical Center, Durham, North Carolina 27510, USA
    Am J Med 114:135-41. 2003
    ..Large pharmaceutical claims databases are useful for detecting potentially harmful prescribing behaviors, but better clinical evidence on medication safety is needed before such a system can be implemented fully...
  88. ncbi request reprint Characteristics of nontraumatic subarachnoid hemorrhage in the United States in 2003
    Alisa M Shea
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA
    Neurosurgery 61:1131-7; discussion 1137-8. 2007
    ..We examined the epidemiology and in-hospital outcomes of nontraumatic SAH in the United States...
  89. ncbi request reprint The insurance effect on prescription drug expenditures among the elderly: findings from the 1997 Medical Expenditure Panel Survey
    Lesley H Curtis
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Med Care 42:439-46. 2004
    ..Despite continuing debate over a prescription drug benefit for the Medicare program, there has been relatively little research estimating the potential cost of providing such a benefit...
  90. ncbi request reprint Comparative effectiveness of beta-blockers in elderly patients with heart failure
    Judith M Kramer
    Department of Medicine, Duke Clinical Research Institute, Durham, NC 27715, USA
    Arch Intern Med 168:2422-8; discussion 2428-32. 2008
    ..We compared the effectiveness of EBBBs vs non-EBBBs on survival...
  91. ncbi request reprint Does the ownership of the admitting hospital make a difference? Outcomes and process of care of Medicare beneficiaries admitted with acute myocardial infarction
    Frank A Sloan
    Department of Economics, Duke University, Durham, North Carolina 27708, USA
    Med Care 41:1193-205. 2003
    ..Concerns have been expressed about quality of for-profit hospitals and their use of expensive technologies...
  92. ncbi request reprint The Medicare Modernization Act and reimbursement for outpatient chemotherapy: do patients perceive changes in access to care?
    Joeëlle Y Friedman
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    Cancer 110:2304-12. 2007
    ....
  93. pmc Medical costs of abnormal serum sodium levels
    Alisa M Shea
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    J Am Soc Nephrol 19:764-70. 2008
    ..2%). Costs associated with hypernatremia were not significantly different from those incurred by patients with normal serum sodium. In conclusion, hyponatremia is a significant independent predictor of 6-mo and 1-yr direct medical costs...
  94. ncbi request reprint Outpatient prescribing of antiarrhythmic drugs from 1995 to 2000
    Sana M Al-Khatib
    Duke Center for Education and Research on Therapeutics CERTs at the Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    Am J Cardiol 91:91-4. 2003
  95. pmc Practice variation in the surgical management of urinary lithiasis
    Charles D Scales
    Division of Urologic Surgery, Duke University Medical Center, Durham, North Carolina, USA
    J Urol 186:146-50. 2011
    ..We identified patient, provider and practice setting characteristics associated with the selection of ureteroscopy or shock wave lithotripsy...
  96. ncbi request reprint Prescription of nonsteroidal anti-inflammatory drugs and muscle relaxants for back pain in the United States
    Xuemei Luo
    Center for Clinical Effectiveness, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA
    Spine (Phila Pa 1976) 29:E531-7. 2004
    ..OBJECTIVE.: To examine national prescription patterns of nonsteroidal anti-inflammatory drugs (NSAIDs) and muscle relaxants among individuals with back pain in the United States...
  97. ncbi request reprint Geographic variations in the use of medical and surgical therapies for benign prostatic hyperplasia
    Jeffrey C Sung
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27715, USA
    J Urol 175:1023-7. 2006
    ..Patients with BPH have several treatment options. Little is known about geographic variations in surgical rates for BPH and the market relationships to medical therapy, health resources and sociodemographic factors...
  98. ncbi request reprint Insurance status and race represent independent predictors of undergoing laparoscopic surgery for appendicitis: secondary data analysis of 145,546 patients
    Ulrich Guller
    Department of Surgery, Division of General Surgery, University of Basel Switzerland
    J Am Coll Surg 199:567-75; discussion 575-7. 2004
    ..Studies have shown that racial and socioeconomic differences lead to inequality in access to health care. It is unknown whether insurance status and race affect the choice of surgical treatment for patients presenting with appendicitis...
  99. ncbi request reprint Trends in operator and hospital procedure volume and outcomes for percutaneous transluminal coronary angioplasty, 1996 to 2001
    Susan M Kansagra
    Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 99:339-43. 2007
    ..There were outcome differences within subpopulations of operators in classes 2 and 4, which suggest possibilities for alternative volume classification guidelines...
  100. pmc Welfare reform and Latinas' use of perinatal health care
    Damon M Seils
    Am J Public Health 92:699-700; author reply 700. 2002

Research Grants4

  1. Heart Failure: Epidemiology & Outcomes in the Elderly
    Lesley Curtis; Fiscal Year: 2006
    ..At the conclusion of this study, we will have a comprehensive understanding of heart failure in elderly Americans and how investments in health care for patients with HF are directly linked to survival and health. ..
  2. Heart Failure: Epidemiology & Outcomes in the Elderly
    Lesley Curtis; Fiscal Year: 2007
    ..At the conclusion of this study, we will have a comprehensive understanding of heart failure in elderly Americans and how investments in health care for patients with HF are directly linked to survival and health. ..
  3. Patterns of Health Care Use, Treatment & Outcomes in Atrial Fibrillation: PATH-AF
    SUSAN HECKBERT; Fiscal Year: 2010
    ..Second, it will directly answer critical questions of how investments in health care for patients with atrial fibrillation are directly linked to survival and health. ..