T J Cummings

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint The pathology of extracranial scalp and skull masses in young children
    T J Cummings
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Clin Neuropathol 23:34-43. 2004
  2. ncbi request reprint Primary intraocular T-cell-rich large B-cell lymphoma
    Thomas J Cummings
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Arch Pathol Lab Med 129:1050-3. 2005
  3. ncbi request reprint TaqMan junction probes and the reverse transcriptase polymerase chain reaction: detection of alveolar rhabdomyosarcoma, synovial sarcoma, and desmoplastic small round cell tumor
    Thomas J Cummings
    Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ann Clin Lab Sci 32:219-24. 2002
  4. ncbi request reprint Extraskeletal myxoid chondrosarcoma of the jugular foramen
    T J Cummings
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Clin Neuropathol 23:232-7. 2004
  5. ncbi request reprint Recovery and expression of messenger RNA from postmortem human brain tissue
    T J Cummings
    Department of Pathology, Duke University Medical Center, Box 3712, Durham, NC 27710, USA
    Mod Pathol 14:1157-61. 2001
  6. ncbi request reprint CD34 and dural fibroblasts: the relationship to solitary fibrous tumor and meningioma
    T J Cummings
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Acta Neuropathol 102:349-54. 2001
  7. ncbi request reprint Ham56-immunoreactive macrophages in untreated infiltrating gliomas
    T J Cummings
    Department of Pathology, Box 3712, Duke University Medical Center, Durham, NC 27710, USA
    Arch Pathol Lab Med 125:637-41. 2001
  8. ncbi request reprint Castleman's disease confined to the leptomeninges
    T J Cummings
    Duke University Medical Center, Durham, North Carolina, Department of Pathology, 27710, USA
    Ann Clin Lab Sci 30:278-82. 2000
  9. ncbi request reprint Fine-needle aspiration diagnosis of psammomatous melanotic schwannoma
    T J Cummings
    Department of Pathology and Cytopathology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Diagn Cytopathol 23:55-8. 2000
  10. ncbi request reprint Gliomas of the optic nerve: histological, immunohistochemical (MIB-1 and p53), and MRI analysis
    T J Cummings
    Duke University Medical Center, Department of Pathology, Durham, NC 27710, USA
    Acta Neuropathol 99:563-70. 2000

Collaborators

Detail Information

Publications54

  1. ncbi request reprint The pathology of extracranial scalp and skull masses in young children
    T J Cummings
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Clin Neuropathol 23:34-43. 2004
    ..Although the most common reported lesion is the dermoid cyst, our experience suggests that the spectrum of pathology in these lesions can present diagnostic challenges to the pathologist...
  2. ncbi request reprint Primary intraocular T-cell-rich large B-cell lymphoma
    Thomas J Cummings
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Arch Pathol Lab Med 129:1050-3. 2005
    ..This case highlights the importance of interpreting cytologic features in vitreous aspirates in the context of the clinical situation...
  3. ncbi request reprint TaqMan junction probes and the reverse transcriptase polymerase chain reaction: detection of alveolar rhabdomyosarcoma, synovial sarcoma, and desmoplastic small round cell tumor
    Thomas J Cummings
    Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ann Clin Lab Sci 32:219-24. 2002
    ....
  4. ncbi request reprint Extraskeletal myxoid chondrosarcoma of the jugular foramen
    T J Cummings
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Clin Neuropathol 23:232-7. 2004
    ..The histological differential diagnosis includes chordoma, conventional chondrosarcoma and chordoid meningioma, among others. A distinguishing feature of EMC is their characteristic reciprocal translocation t(9;22)(q22;q12)...
  5. ncbi request reprint Recovery and expression of messenger RNA from postmortem human brain tissue
    T J Cummings
    Department of Pathology, Duke University Medical Center, Box 3712, Durham, NC 27710, USA
    Mod Pathol 14:1157-61. 2001
    ..However, we caution that the successful expression of certain genes from postmortem brain tissue may require enhanced procurement efforts to maximize RNA integrity...
  6. ncbi request reprint CD34 and dural fibroblasts: the relationship to solitary fibrous tumor and meningioma
    T J Cummings
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Acta Neuropathol 102:349-54. 2001
    ..Our results suggest that SFTs and dural-based fibrous nodules derive from CD34-positive dural-based fibroblasts, and that CD34 reactivity in meningiomas may result from inclusion of dural fibroblasts within the neoplasm...
  7. ncbi request reprint Ham56-immunoreactive macrophages in untreated infiltrating gliomas
    T J Cummings
    Department of Pathology, Box 3712, Duke University Medical Center, Durham, NC 27710, USA
    Arch Pathol Lab Med 125:637-41. 2001
    ..The knowledge of macrophage distribution should prove useful when confronted with an infiltrating glioma containing macrophages...
  8. ncbi request reprint Castleman's disease confined to the leptomeninges
    T J Cummings
    Duke University Medical Center, Durham, North Carolina, Department of Pathology, 27710, USA
    Ann Clin Lab Sci 30:278-82. 2000
    ..The patient is disease-free five years after surgical resection. To our knowledge, clonal gene rearrangement has not been previously reported in the plasma cell variant of localized intracranial Castleman's disease...
  9. ncbi request reprint Fine-needle aspiration diagnosis of psammomatous melanotic schwannoma
    T J Cummings
    Department of Pathology and Cytopathology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Diagn Cytopathol 23:55-8. 2000
    ..The patient has declined the recommendation of surgical excision of the mass. We herein describe a case unequivocally diagnosed as psammomatous melanotic schwannoma by FNAB...
  10. ncbi request reprint Gliomas of the optic nerve: histological, immunohistochemical (MIB-1 and p53), and MRI analysis
    T J Cummings
    Duke University Medical Center, Department of Pathology, Durham, NC 27710, USA
    Acta Neuropathol 99:563-70. 2000
    ....
  11. ncbi request reprint March 2000: A 16 year old female with a cerebellar mass
    T J Cummings
    Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA
    Brain Pathol 11:391-3. 2001
    ..Patient's diagnosed with Lhermitte-Duclos disease must be adequately evaluated for Cowden's syndrome...
  12. ncbi request reprint Meningioma with eosinophilic granular inclusions
    R T Alexander
    Duke University Medical Center, Durham, NC, USA
    Clin Neuropathol 23:292-7. 2004
    ..The inclusions within this tumor had histochemical, immunohistochemical and ultrastructural properties not described in other reported meningiomas with eosinophilic granular or granulofilamentous inclusions...
  13. ncbi request reprint Parasitic lesion of the insula suggesting cerebral sparganosis: case report
    T J Cummings
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Neuroradiology 42:206-8. 2000
    ..We describe the MRI appearances and pathologic features. Intracranial mass lesions secondary to sparganosis must be considered in patients with a history of travel to endemic areas, especially Asia...
  14. ncbi request reprint The immunohistochemical profile of the myelomeningocele placode: is the placode normal?
    Timothy M George
    Pediatric Neurosurgery Service, Duke University Medical Center, Durham, NC 27710, USA
    Pediatr Neurosurg 39:234-9. 2003
    ..Additionally, injury to the placode was also demonstrated. The combination of effects may be contributory to abnormal spinal cord function in myelomeningocele patients...
  15. ncbi request reprint Spinal capillary hemangioma in infants: report of two cases and review of the literature
    Isaac O Karikari
    Pediatric Neurosurgery Service, Duke University Medical Center, Durham, NC 27710, USA
    Pediatr Neurosurg 43:125-9. 2007
    ..We provide a review of the literature of spinal capillary hemangiomas and support the practice of evaluating infants with cutaneous lumbosacral hemangiomas for underlying spinal cord abnormalities...
  16. ncbi request reprint Retinal folds as initial manifestation of orbital lymphangioma
    Sherman W Reeves
    Duke University Eye Center, Durham, NC 27710, USA
    Arch Ophthalmol 123:1756-8. 2005
  17. ncbi request reprint Myxopapillary ependymoma and fatty filum in an adult with tethered cord syndrome: a shared embryological lesion? Case report
    D Cory Adamson
    Division of Neurosurgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Neurosurgery 57:E373; discussion E373. 2005
    ..Myxopapillary ependymoma and fatty fila are traditionally thought to arise via completely different pathophysiologies. Recognition of these distinct pathologies in the same patient is important for appropriate treatment and prognosis...
  18. ncbi request reprint The immunohistochemical profile of the tethered filum terminale
    Timothy M George
    Department of Pediatric Neurosurgery, Duke University Medical Center, Durham, NC 27710, USA
    Pediatr Neurosurg 39:227-33. 2003
    ..The change in expression may be indicative of altered cell identity in the filum and constitute the predisposition to tethering...
  19. doi request reprint Hybrid neurofibroma-schwannoma of the orbit
    Kenneth E Youens
    Department of Pathology, Duke University Medical Center, Durham, North Carolina 27713, USA
    Orbit 27:223-5. 2008
    ..To report a case of an unusual orbital tumor with histologic features of both neurofibroma and schwannoma...
  20. pmc Convection-enhanced delivery of free gadolinium with the recombinant immunotoxin MR1-1
    Dale Ding
    School of Medicine, Duke University Medical Center, DUMC, Box 3050, 220 Sands Building, Research Drive, Durham, NC 27710, USA
    J Neurooncol 98:1-7. 2010
    ..Our data supports the use of Gd-DTPA, as a surrogate tracer, co-infused with MR1-1 for drug distribution monitoring in patients with GBM...
  21. doi request reprint Angiosarcoma of the eyelid: a clinicopathologic comparison between isolated unilateral tumors and tumors demonstrating extrapalpebral involvement
    John A Papalas
    Departments of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Am J Dermatopathol 32:694-9. 2010
    ..When extrapalpebral involvement is ruled out by clinical and radiographic examination, patients with isolated involvement seem to fare better compared with patients with eyelid involvement secondary to more regionally extensive tumors...
  22. ncbi request reprint Neurothekeoma palpebrae: A report of 3 cases
    John A Papalas
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Am J Dermatopathol 32:374-9. 2010
    ..Although uncommon, these lesions should be kept in the differential diagnosis of eyelid tumors that can masquerade as chalazia...
  23. doi request reprint Ectopic brain in the orbit presenting as disc edema in an adult
    Kristina M Price
    Department of Ophthalmology, Duke University Medical Center, Durham, NC 27705, USA
    Orbit 28:74-7. 2009
    ..The few reports in the literature of sequestered ectopic brain in the orbit have all involved neonates or infants. We describe the first case of this rare tumor presenting in the orbit of an adult...
  24. ncbi request reprint Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model
    Jeremy N Rich
    Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    J Biol Chem 278:15951-7. 2003
    ..Genetically defined human cancer models offer useful tools in functional genomics to define the roles of specific genes in late stages of carcinogenesis...
  25. ncbi request reprint Loss of chromosome 13 in a case of soft tissue perineurioma
    R T Mott
    Duke University Medical Center, Department of Pathology, Durham, NC 27710, USA
    Clin Neuropathol 24:69-76. 2005
    ..Herein, we discuss this case and provide a review of the literature...
  26. ncbi request reprint Endodermal cyst of the oculomotor nerve
    M A Morgan
    School of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Neuroradiology 43:1063-6. 2001
    ..She underwent craniotomy, biopsy, slit resection, and drainage of the cyst. To our knowledge, endodermal cysts have not been previously described in relation to the oculomotor nerve...
  27. ncbi request reprint Primary intracerebral Hodgkin lymphoma with recurrence
    W C Foo
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Clin Neuropathol 30:75-9. 2011
    ..To report a case of primary intracerebral Hodgkin lymphoma with disease recurrence...
  28. ncbi request reprint Fine-needle aspiration diagnosis of medulloblastoma metastatic to the pelvis
    K C New
    Department of Surgery, Division of Neurosurgery, Duke University Medical Center, Durham, North Carolina, USA
    Diagn Cytopathol 24:361-3. 2001
    ..The diagnosis of metastatic medulloblastoma is usually suspected clinically or radiographically, and is uncommonly confirmed by cytologic evaluation. Here we report on a rare case of FNAB used to diagnose metastatic medulloblastoma...
  29. ncbi request reprint Expression of the intermediate filament peripherin in extraskeletal myxoid chondrosarcoma
    T J Cummings
    Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA
    J Cutan Pathol 27:141-6. 2000
    ..The finding of peripherin expression in some extraskeletal myxoid chondrosarcomas may suggest the ability of some tumors to demonstrate both neural and chondroid differentiation...
  30. ncbi request reprint Malignant peripheral nerve sheath tumor of the spine after radiation therapy for Hodgkin's lymphoma
    D C Adamson
    Division of Neurosurgery, Duke University Medical Center, Durham, NC 27710, USA
    Clin Neuropathol 23:245-55. 2004
    ..Postirradiation MPNST should be considered in the differential diagnosis of a painful, enlarging mass in a previously irradiated area...
  31. ncbi request reprint Clear cell hidradenoma: a mimic of metastatic clear cell tumors
    Keith E Volmar
    Department of Pathology, Duke University Medical Center, Durham, NC 27599, USA
    Arch Pathol Lab Med 129:e113-6. 2005
    ..We report the rare case of a patient with renal cell carcinoma who underwent excision of an axillary clear cell hidradenoma, which was clinically suggestive of cutaneous metastatic disease...
  32. doi request reprint Secretory meningiomas of the orbit
    Isaac O Karikari
    Division of Neurosurgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Orbit 28:408-11. 2009
    ..The secretory meningioma is a well-differentiated variant, is relatively rare. Orbital involvement of secretory meningiomas is rarity. We report two cases of secretory meningiomas of orbit and review of current literature...
  33. ncbi request reprint Prognostic value of magnetic resonance imaging-guided stereotactic biopsy in the evaluation of recurrent malignant astrocytoma compared with a lesion due to radiation effect
    Matthew J McGirt
    Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosurg 98:14-20. 2003
    ..The prognostic value of differentiating between recurrent malignant glioma and a lesion due to radiation effect by performing stereotactic biopsy has not been assessed. Thus, this study was undertaken to determine such value...
  34. ncbi request reprint Dementia with Lewy bodies and Alzheimer's disease
    C K Rosenberg
    Bryan Alzheimer's Disease Research Center, Department of Medicine, Division of Neurology, Box 2900, Duke University Medical Center, Durham, NC 27710, USA
    Acta Neuropathol 102:621-6. 2001
    ..These data suggest that Lewy bodies are more common in males affected with dementia, especially those with the APOE 3/4 genotype...
  35. ncbi request reprint Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells
    Peter E Fecci
    Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Clin Cancer Res 12:4294-305. 2006
    ..We therefore examined T(regs) in mice bearing malignant glioma and evaluated anti-CD25 as an immunotherapeutic adjunct...
  36. doi request reprint Disappearing bone disease and Chiari I malformation
    Betsy D Hughes
    Division of Neurosurgery, Duke University Medical Center, Durham, NC 27710, USA
    Pediatr Neurosurg 46:58-61. 2010
    ..We describe a case of Chiari I malformation in a patient with this rare disorder, with treatment consisting of a suboccipital craniectomy, C1 laminectomy, and duraplasty for Chiari decompression...
  37. ncbi request reprint A lethal association of congenital apnea with brainstem tegmental necrosis
    Martin P Moya
    Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA
    Pediatr Neurol 30:219-21. 2004
    ..Neuropathologic findings at postmortem examination were consistent with brainstem tegmental necrosis and olivary hypoplasia, a rare lethal entity that should be considered in the differential diagnosis of congenital apnea...
  38. doi request reprint Primary intramedullary melanocytoma of the spinal cord: case report
    Isaac O Karikari
    Division of Neurosurgery, Duke University Medical Center, Durham, North Carolina, USA
    Neurosurgery 64:E777-8; discussion E778. 2009
    ..The authors report 2 cases of primary intramedullary spinal melanocytomas in 2 patients who presented with lower extremity numbness and/or weakness...
  39. ncbi request reprint Optic nerve compression in infantile malignant autosomal recessive osteopetrosis
    Thomas J Cummings
    Duke University Medical Center, Department of Pathology, Durham, North Carolina, USA
    J Pediatr Ophthalmol Strabismus 41:241-4. 2004
    ..Unrelated umbilical cord blood transplantation was performed. Four months later, the infant died of respiratory complications...
  40. ncbi request reprint Choroidal metastasis of follicular thyroid adenocarcinoma diagnosed by 25-gauge transretinal biopsy
    Adrienne W Scott
    Department of Ophthalmology, Albert Eye Research Institute, Duke University Eye Center, Durham, NC 27710, USA
    Ann Ophthalmol (Skokie) 40:110-2. 2008
    ..A 25-gauge vitrector was used to perform transretinal choroidal biopsy (TRCB), confirming the diagnosis of metastatic follicular thyroid carcinoma...
  41. ncbi request reprint Complex choristoma of the gyrus rectus: a distinct clinicopathologic entity?
    Ty W Abel
    Department of Pathology, Vanderbilt University Medical Center, 1161 21st Avenue South, Nashville, TN 37232, USA
    Am J Surg Pathol 30:625-9. 2006
    ..By location and histologic features, this lesion appears to represent a rare, distinct clinicopathologic entity, perhaps derived from misplaced cranial neural crest cells...
  42. doi request reprint Cholesterol granuloma of the lateral ventricle. Case report
    Peter M Grossi
    Department of Surgery, Division of Neurosurgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Neurosurg 108:357-60. 2008
    ..The authors describe the presentation, imaging findings, histopathological characteristics, and surgical treatment of this rare lesion and related pathological entities...
  43. doi request reprint Stage IV primitive-appearing sinus and orbital rhabdomyosarcoma presenting in a 68-year-old female previously treated for breast cancer
    Carrie L Morris
    Department of Ophthalmology, Duke University Eye Center, Duke University Medical Center, Durham, NC, USA
    Orbit 27:73-7. 2008
    ..In our patient with atypical demographics for rhabdomyosarcoma, the previous neoplasm and treatment thereof may have predisposed to the development of this rare tumor...
  44. ncbi request reprint Behavioural testing and histological assessments of rabbit spinal cord following intrathecal administration of ondansetron
    Hector J Lacassie
    Division of Women s Anaesthesia, Department of Anaesthesiology, Duke University Medical Center, Durham, North Carolina, USA
    Clin Exp Pharmacol Physiol 33:798-801. 2006
    ..4. Collectively, these negative findings support conducting further experiments to fully assess the clinical usefulness of intrathecal ondansetron administration...
  45. ncbi request reprint Pathologic quiz case: left eye proptosis, ptosis, and blindness. Hemangiopericytoma of the orbit
    Kelly J Butnor
    Department of Pathology, Duke University Medical Center, Durham, NC, USA
    Arch Pathol Lab Med 126:1555-6. 2002
  46. doi request reprint Corneal wound architecture and integrity after torsional and mixed phacoemulsification: evaluation of standard and microincisional coaxial techniques
    Bokkwan Jun
    Erwin Road Box 3802, Duke University Eye Center, Durham, NC 27710, USA
    Ophthalmic Surg Lasers Imaging 41:128-34. 2010
    ..To compare the effects of torsional and mixed ultrasound on clear corneal incision architecture, wound integrity, and apposition using standard (2.75 mm) and microincisional (2.2 mm) coaxial phacoemulsification...
  47. ncbi request reprint Intracranial Ewing sarcoma
    Melissa A Mazur
    Department of Pediatric Hematology Oncology, Duke University Medical Center, Durham, NC 27710, USA
    Pediatr Blood Cancer 45:850-6. 2005
    ..Demonstration of t(11;22)(q24;q12) by molecular analysis essentially confirms the diagnosis and enables the oncologist to choose appropriate therapy...
  48. ncbi request reprint Primary spinal intramedullary adrenal cortical adenoma associated with spinal dysraphism: case report
    Isaac O Karikari
    Neurosurgery Service, Duke University Medical Center, Durham, North Carolina, USA
    Neurosurgery 59:E1144; discussion E1144. 2006
    ..The authors report a primary spinal intramedullary adrenal cortical adenoma in a patient with spinal dysraphism presenting with bilateral leg pain and urinary frequency...
  49. doi request reprint Response of malignant scalp dermatofibrosarcoma to presurgical targeted growth factor inhibition
    Austin K Mattox
    Preston Robert Tisch Brain Tumor Center, Duke Medical Center, Durham, North Carolina 27710, USA
    J Neurosurg 112:965-77. 2010
    ..Although wide excision and Mohs micrographic surgery remain the standard surgical treatments for DFSP, the authors illustrate that presurgical chemotherapeutic treatment by imatinib provides a critical adjunct to traditional therapy...
  50. ncbi request reprint Radial optic neurotomy in the porcine eye without retinal vein occlusion
    Marcin P Czajka
    Department of Ophthalmology, Duke University School of Medicine, Durham, NC, USA
    Arch Ophthalmol 122:1185-9. 2004
    ..To demonstrate the histopathologic changes in the porcine eye without retinal vein occlusion after radial optic neurotomy (RON)...
  51. ncbi request reprint Primary cerebral ALK-1-positive anaplastic large cell lymphoma in a child. Case report and literature review
    Isaac O Karikari
    Pediatric Neurosurgery Service, Duke University Medical Center, Durham, NC, USA
    Pediatr Neurosurg 43:516-21. 2007
    ..We describe a case of a rapidly deteriorating clinical course in a child with central nervous system ALCL and review the current literature on ALCL occurring in the central nervous system...
  52. ncbi request reprint Pathologic quiz case: acute-onset paraplegia in a 60-year-old woman. Spinal cord infarction secondary to fibrocartilaginous (intervertebral disk) embolism
    Russell T Alexander
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Arch Pathol Lab Med 127:1047-8. 2003
  53. doi request reprint Postoperative delirium
    Gregory L Fricchione
    Massachusetts General Hospital, Department of Psychiatry, Warren 615, 55 Fruit St, Boston, MA 02114, USA
    Am J Psychiatry 165:803-12. 2008
  54. ncbi request reprint Lymphomas and high-grade astrocytomas: comparison of water diffusibility and histologic characteristics
    Alexander C Guo
    Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710, USA
    Radiology 224:177-83. 2002
    ..To determine if water diffusivity within lymphomas and high-grade astrocytomas correlates with cellularity...