Michael L Cuccaro

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint Analysis of the autism chromosome 2 linkage region: GAD1 and other candidate genes
    Raquel Rabionet
    Department of Medicine, Center for Human Genetics, 595 LaSalle St, Box 3445, Duke University Medical Center, Durham, NC 27710, USA
    Neurosci Lett 372:209-14. 2004
  2. pmc Investigation of autism and GABA receptor subunit genes in multiple ethnic groups
    Ann L Collins
    Center for Human Genetics, Duke University Medical Center, Durham, NC, USA
    Neurogenetics 7:167-74. 2006
  3. ncbi request reprint Mapping autism risk loci using genetic linkage and chromosomal rearrangements
    Peter Szatmari
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario L8N 3Z5, Canada
    Nat Genet 39:319-28. 2007
  4. ncbi request reprint A comparison of repetitive behaviors in Aspergers Disorder and high functioning autism
    Michael L Cuccaro
    Duke University Medical Center, Durham, NC, USA
    Child Psychiatry Hum Dev 37:347-60. 2007
  5. ncbi request reprint Factor analysis of restricted and repetitive behaviors in autism using the Autism Diagnostic Interview-R
    Michael L Cuccaro
    Center for Human Genetics, Duke University Medical Center, Durham, NC 27710, USA
    Child Psychiatry Hum Dev 34:3-17. 2003
  6. ncbi request reprint Lack of association between autism and SLC25A12
    Raquel Rabionet
    Center for Human Genetics, Department of Medicine, Duke University Medical Center, 595 LaSalle St, Durham, NC 27710, USA
    Am J Psychiatry 163:929-31. 2006
  7. pmc Phenotypic homogeneity provides increased support for linkage on chromosome 2 in autistic disorder
    Yujun Shao
    Center for Human Genetics, CARL Building, Duke University Medical Center, Durham, NC 27710, USA
    Am J Hum Genet 70:1058-61. 2002
  8. ncbi request reprint Autism in African American families: clinical-phenotypic findings
    Michael L Cuccaro
    Duke University Medical Center, Durham, NC, USA
    Am J Med Genet B Neuropsychiatr Genet 144:1022-6. 2007
  9. ncbi request reprint Factor analysis of the aberrant behavior checklist in individuals with autism spectrum disorders
    Jason Brinkley
    Center for Human Genetics, Duke University Medical Center, DUMC Box 3445, Durham, NC 27710, USA
    J Autism Dev Disord 37:1949-59. 2007
  10. ncbi request reprint No association between the WNT2 gene and autistic disorder
    Pinky A McCoy
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Am J Med Genet 114:106-9. 2002

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Analysis of the autism chromosome 2 linkage region: GAD1 and other candidate genes
    Raquel Rabionet
    Department of Medicine, Center for Human Genetics, 595 LaSalle St, Box 3445, Duke University Medical Center, Durham, NC 27710, USA
    Neurosci Lett 372:209-14. 2004
    ....
  2. pmc Investigation of autism and GABA receptor subunit genes in multiple ethnic groups
    Ann L Collins
    Center for Human Genetics, Duke University Medical Center, Durham, NC, USA
    Neurogenetics 7:167-74. 2006
    ..0253). These results confirmed our earlier findings, indicating GABRA4 and GABRB1 as genes contributing to autism susceptibility, extending the effect to multiple ethnic groups and suggesting seizures as a stratifying phenotype...
  3. ncbi request reprint Mapping autism risk loci using genetic linkage and chromosomal rearrangements
    Peter Szatmari
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario L8N 3Z5, Canada
    Nat Genet 39:319-28. 2007
    ..Neurexins team with previously implicated neuroligins for glutamatergic synaptogenesis, highlighting glutamate-related genes as promising candidates for contributing to ASDs...
  4. ncbi request reprint A comparison of repetitive behaviors in Aspergers Disorder and high functioning autism
    Michael L Cuccaro
    Duke University Medical Center, Durham, NC, USA
    Child Psychiatry Hum Dev 37:347-60. 2007
    ..These findings add to the body of literature showing that HFA and ASP fail to differ with respect to repetitive behaviors. The implications of the findings for neurobiologic and genetic studies are discussed...
  5. ncbi request reprint Factor analysis of restricted and repetitive behaviors in autism using the Autism Diagnostic Interview-R
    Michael L Cuccaro
    Center for Human Genetics, Duke University Medical Center, Durham, NC 27710, USA
    Child Psychiatry Hum Dev 34:3-17. 2003
    ..Defining subgroups within autism will allow for reduction of clinical heterogeneity and enhance our ability to dissect the genetic etiology of this complex disorder...
  6. ncbi request reprint Lack of association between autism and SLC25A12
    Raquel Rabionet
    Center for Human Genetics, Department of Medicine, Duke University Medical Center, 595 LaSalle St, Durham, NC 27710, USA
    Am J Psychiatry 163:929-31. 2006
    ..This study aimed to test for association in SLC25A12 in an independent data set of 327 families with autistic offspring...
  7. pmc Phenotypic homogeneity provides increased support for linkage on chromosome 2 in autistic disorder
    Yujun Shao
    Center for Human Genetics, CARL Building, Duke University Medical Center, Durham, NC 27710, USA
    Am J Hum Genet 70:1058-61. 2002
    ..86 and HLOD 2.12 for marker D2S116). These data support evidence for a gene on chromosome 2 contributing to risk of AutD, and they suggest that phenotypic homogeneity increases the power to find susceptibility genes for AutD...
  8. ncbi request reprint Autism in African American families: clinical-phenotypic findings
    Michael L Cuccaro
    Duke University Medical Center, Durham, NC, USA
    Am J Med Genet B Neuropsychiatr Genet 144:1022-6. 2007
    ..Such considerations will aid greatly in the search for genetic variants in autism...
  9. ncbi request reprint Factor analysis of the aberrant behavior checklist in individuals with autism spectrum disorders
    Jason Brinkley
    Center for Human Genetics, Duke University Medical Center, DUMC Box 3445, Durham, NC 27710, USA
    J Autism Dev Disord 37:1949-59. 2007
    ..The emergence of a self-injury factor, while not suggestive of a new subscale, warrants further exploration as a tool that could help dissect relevant neurobiobehavioral groups in ASD...
  10. ncbi request reprint No association between the WNT2 gene and autistic disorder
    Pinky A McCoy
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Am J Med Genet 114:106-9. 2002
    ..We did not identify any activating mutation in the coding region of the WNT2 gene. Thus, we conclude that activating mutations of the WNT2 gene are not a major contributor to the development of autistic disorder in these data...
  11. ncbi request reprint Accelerated head growth in early development of individuals with autism
    Yulia A Dementieva
    Department of Medicine and Center for Human Genetics, Duke University Medical Center, Durham, NC 27710, USA
    Pediatr Neurol 32:102-8. 2005
    ..This study confirms the presence of abnormal acceleration in head growth during the first and second months of life in a subgroup of autistic individuals...
  12. ncbi request reprint Investigation of potential gene-gene interactions between APOE and RELN contributing to autism risk
    Allison E Ashley-Koch
    Center for Human Genetics, Department of Medicine, Duke University Medical Center, Snyderman Genomic Sciences Building, Durham, NC 27710, USA
    Psychiatr Genet 17:221-6. 2007
    ..RELN shares a common biological pathway with APOE, and Persico et al. have observed transmission distortion of the APOE-2 allele in autism families...
  13. ncbi request reprint Identification of MeCP2 mutations in a series of females with autistic disorder
    Regina M Carney
    Department of Medicine and the Center for Human Genetics, Duke University Medical Center, Durham, North Carolina 27710, USA
    Pediatr Neurol 28:205-11. 2003
    ..These data provide additional evidence of variable expression in the Rett disorder phenotype and suggest MeCP2 testing may be warranted for females presenting with autistic disorder...
  14. ncbi request reprint Genomic screen and follow-up analysis for autistic disorder
    Yujun Shao
    Department of Medicine and Center for Human Genetics, Duke University Medical Center, Durham, North Carolina 27710, USA
    Am J Med Genet 114:99-105. 2002
    ..0) in stage two analysis. The peak lod score regions on chromosomes 2, 7, 15, 19, and X overlap previously reported peak linkage areas. The region on chromosome 3 is unique...
  15. ncbi request reprint Ordered-subset analysis of savant skills in autism for 15q11-q13
    D Q Ma
    Center for Human Genetics, Duke University Medical Center, Durham, North Carolina 27710, USA
    Am J Med Genet B Neuropsychiatr Genet 135:38-41. 2005
    ..In addition, ordered subset analysis (OSA) using SSF as a covariate also failed to show evidence for linkage. Our findings do not support savant skills as an informative phenotypic subset for linkage in our sample...
  16. ncbi request reprint Behavioral comparisons in autistic individuals from multiplex and singleton families
    Michael L Cuccaro
    W S Hall Psychiatric Institute, Department of Neuropsychiatry, University of South Carolina, Columbia, South Carolina, USA
    J Autism Dev Disord 33:87-91. 2003
    ..These results suggests the possibility that common etiologic mechanisms, either genetic and/or environmental, could underlie all of AD...
  17. pmc Genomic and epigenetic evidence for oxytocin receptor deficiency in autism
    Simon G Gregory
    Duke Center for Human Genetics, DUMC, Durham, NC, USA
    BMC Med 7:62. 2009
    ..Although numerous approaches have been used to identify genes implicated in the development of autism, less than 10% of autism cases have been attributed to single gene disorders...
  18. ncbi request reprint Repetitive behaviors in autism: relationships with associated clinical features
    Robin L Gabriels
    Department of Psychiatry, University of Colorado Health Sciences Center, Denver, CO, USA
    Res Dev Disabil 26:169-81. 2005
    ..The relationship between RBs and associated clinical features in autism is complex and future studies should control for cognitive ability when examining the direct and indirect relationships of these variables with RBs...