Research Topics
| Luke F ChenSummaryAffiliation: Duke University Medical Center Country: USA Publications
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Detail Information
Publications
Observing and improving hand hygiene compliance: implementation and refinement of an electronic-assisted direct-observer hand hygiene audit programLuke F Chen
Duke Program for Infection Prevention and Healthcare Epidemiology, Duke University Medical Center, Durham, NC, USA
Infect Control Hosp Epidemiol 34:207-10. 2013..We improved the reliability and utility of the data by standardizing audit processes, regularly retraining auditors, developing an audit guidance tool, and reporting weighted composite hand hygiene compliance scores...- Cluster of oseltamivir-resistant 2009 pandemic influenza A (H1N1) virus infections on a hospital ward among immunocompromised patients--North Carolina, 2009Luke F Chen
Program for Infection Prevention and Healthcare Epidemiology, Duke University Medical Center, Durham, North Carolina 27710, USA
J Infect Dis 203:838-46. 2011..Oseltamivir resistance among 2009 pandemic influenza A (H1N1) viruses (pH1N1) is rare. We investigated a cluster of oseltamivir-resistant pH1N1 infections in a hospital ward... 
Community-Acquired Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections: Management and PreventionLuke F Chen
Program for Infection Prevention and Healthcare Epidemiology, Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Erwin Road, Durham, NC, 27710, USA
Curr Infect Dis Rep 13:442-50. 2011..The article also summarizes current therapeutic options for CA-MRSA as well as strategies to reduce the transmission and the impact of CA-MRSA in both community and health care settings...- Current use for old antibacterial agents: polymyxins, rifamycins, and aminoglycosidesLuke F Chen
Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Box 102359, Hanes House, Durham, NC 27710, USA
Med Clin North Am 95:819-42, viii-ix. 2011..The aminoglycosides are used mainly as companion drugs for the treatment of resistant gram-negative bacillary infections and for gram-positive coccal endocarditis... - Pathogens resistant to antibacterial agentsLuke F Chen
Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Box 102359, Hanes House, Durham, NC 27710, USA
Med Clin North Am 95:647-76, vii. 2011..This article reviews the epidemiology, molecular mechanisms of resistance, and treatment options for pathogens resistant to antimicrobial drugs... 
Validating a 3-point prediction rule for surgical site infection after coronary artery bypass surgeryLuke F Chen
Division of Infectious Diseases and International Health, Duke University Medical Center, Durham, North Carolina, USA
Infect Control Hosp Epidemiol 31:64-8. 2010..Investigators from Australia proposed a new, 3-point scale that assesses SSI risk on the basis of diagnosis of diabetes mellitus and body mass index...- Current use for old antibacterial agents: polymyxins, rifamycins, and aminoglycosidesLuke F Chen
Department of Medicine, Division of Infectious Diseases and International Health, Duke University Medical Center, Box 102359, Hanes House, Durham, NC 27710, USA
Infect Dis Clin North Am 23:1053-75, x. 2009..The aminoglycosides are used mainly as companion drugs for the treatment of resistant gram-negative bacillary infections and for gram-positive coccal endocarditis... - Pathogens resistant to antibacterial agentsLuke F Chen
Department of Medicine, Division of Infectious Diseases and International Health, Duke University Medical Center, Box 102359, Hanes House, Durham, NC 27710, USA
Infect Dis Clin North Am 23:817-45, vii. 2009..This article reviews the epidemiology, molecular mechanisms of resistance, and treatment options for pathogens resistant to antimicrobial drugs... - Patient-days: a better measure of incidence of occupational bloodborne exposuresLuke F Chen
Division of Infectious Diseases, Duke Infection Control Outreach Network, Duke University Medical Center, Durham, NC 27710, USA
Am J Infect Control 37:534-40. 2009..There is currently no accepted standard denominator to calculate and to report the incidence of occupational exposures to bloodborne pathogens (OEBBPs) in health care... - What's new in Rocky Mountain spotted fever?Luke F Chen
Division of Infectious Diseases and International Health, Duke University Medical Center, DUMC Box 3824, Durham, NC, 27710, USA
Infect Dis Clin North Am 22:415-32, vii-viii. 2008..Decisions about giving empiric therapy to such patients are difficult and require skill and careful judgement... - Clinical and financial outcomes due to methicillin resistant Staphylococcus aureus surgical site infection: a multi-center matched outcomes studyDeverick J Anderson
Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Duke Infection Control Outreach Network, Durham, North Carolina, USA
PLoS ONE 4:e8305. 2009..The clinical and financial outcomes of SSIs directly attributable to MRSA and methicillin-resistance are largely uncharacterized. Previously published data have provided conflicting conclusions... - The network approach for prevention of healthcare-associated infections: long-term effect of participation in the Duke Infection Control Outreach NetworkDeverick J Anderson
Duke Infection Control Outreach Network, Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
Infect Control Hosp Epidemiol 32:315-22. 2011..To describe the rates of several key outcomes and healthcare-associated infections (HAIs) among hospitals that participated in the Duke Infection Control Outreach Network (DICON)... - "What the eyes don't see, the heart doesn't grieve over": epidemiology and risk factors for bloodstream infections following cardiac catheterizationKristen V Dicks
Internal Medicine Residency Program, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
Infect Control Hosp Epidemiol 33:837-41. 2012..We proposed a novel case definition and determined the epidemiology and risk factors of BSIs after CC procedure using this new definition... - Poor functional status as a risk factor for surgical site infection due to methicillin-resistant Staphylococcus aureusDeverick J Anderson
Department of Medicine, Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina 27710, USA
Infect Control Hosp Epidemiol 29:832-9. 2008..To identify risk factors for surgical site infection (SSI) due to methicillin-resistant Staphylococcus aureus (MRSA)... - Comparison of the burdens of hospital-onset, healthcare facility-associated Clostridium difficile Infection and of healthcare-associated infection due to methicillin-resistant Staphylococcus aureus in community hospitalsBecky A Miller
Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, USA
Infect Control Hosp Epidemiol 32:387-90. 2011..Our data suggest that C. difficile has replaced MRSA as the most common etiology of HAI in community hospitals in the southeastern United States... - Risk factors for gram-negative bacterial surgical site infection: do allergies to antibiotics increase risk?Jane V Trinh
Duke University Medical Center, Durham, North Carolina 27704, USA
Infect Control Hosp Epidemiol 30:440-6. 2009..To determine the relationship between inadequate antimicrobial prophylaxis and development of gram-negative bacterial (GNB) surgical site infection (SSI)... - The effect of surgical site infection on older operative patientsKeith S Kaye
Duke University Medical Center, Durham, North Carolina, USA
J Am Geriatr Soc 57:46-54. 2009..To determine the effect of surgical site infection (SSI) on mortality, duration of hospitalization, and hospital cost in older operative patients... - Complex surgical site infections and the devilish details of risk adjustment: important implications for public reportingDeverick J Anderson
Duke Infection Control Outreach Network, Duke University Medical Center, Durham, North Carolina 27710, USA
Infect Control Hosp Epidemiol 29:941-6. 2008..To validate the National Nosocomial Infection Surveillance (NNIS) risk index as a tool to account for differences in case mix when reporting rates of complex surgical site infection (SSI)... - Epidemiology and outcome of major postoperative infections following cardiac surgery: risk factors and impact of pathogen typeLuke F Chen
Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Am J Infect Control 40:963-8. 2012..Major postoperative infections (MPIs) are poorly understood complications of cardiac surgery. We examined the epidemiology, microbiology, and outcome of MPIs occurring after cardiac surgery... - Efficacy and safety of fidaxomicin compared with oral vancomycin for the treatment of adults with Clostridium difficile-associated diarrhea: data from the OPT-80-003 and OPT-80-004 studiesLuke F Chen
Program for Infection Prevention and Healthcare Epidemiology, Duke University Medical Center, Durham, NC 27710, USA
Future Microbiol 7:677-83. 2012..Despite these potential advantages, the cost-effectiveness of this expensive agent remains poorly understood... - The impact of depth of infection and postdischarge surveillance on rate of surgical-site infections in a network of community hospitalsDavid Y Ming
Duke University Medical Center, Duke Program for Infection Prevention and Healthcare Epidemiology, Duke Infection Control Outreach Network DICON, Duke University Prevention Epicenter Program, Durham, NC 27710, USA
Infect Control Hosp Epidemiol 33:276-82. 2012.... - Constructing unit-specific empiric treatment guidelines for catheter-related and primary bacteremia by determining the likelihood of inadequate therapyMegan E Davis
Department of Pharmacy, Duke University Health System, Durham, North Carolina, USA
Infect Control Hosp Epidemiol 33:416-20. 2012..Our study demonstrates that LIT may reveal differences in traditional antibiograms... - Seasonal variation in Klebsiella pneumoniae bloodstream infection on 4 continentsDeverick J Anderson
Duke University Medical Center, Durham, North Carolina 27710, USA
J Infect Dis 197:752-6. 2008..The objective of this study was to determine whether the incidence of K. pneumoniae bloodstream infection (BSI) was higher during warm months... - Decontamination of targeted pathogens from patient rooms using an automated ultraviolet-C-emitting deviceDeverick J Anderson
Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, North Carolina
Infect Control Hosp Epidemiol 34:466-71. 2013..Reductions similarly occurred in direct and indirect line of sight. Conclusions. Our data confirm that automated UV-C-emitting devices can decrease the bioburden of important pathogens in real-world settings such as hospital rooms... - Colonization, pathogenicity, host susceptibility, and therapeutics for Staphylococcus aureus: what is the clinical relevance?Steven Y C Tong
Division of Infectious Diseases and International Health, Duke University Medical Center, Box 102359, Durham, NC 27705, USA
Semin Immunopathol 34:185-200. 2012..Although progress has been made in the past decade, we are likely to face further surprises such as the recent waves of community-associated MRSA... - Correlation of cross-sectional diameter with image quality and radiation exposure in MDCT examinations of the neckJenny K Hoang
Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA
AJR Am J Roentgenol 197:W904-9. 2011..The purpose of this study was to identify an optimal cross-sectional neck diameter that correlates with image quality and radiation exposure in MDCT examinations of the neck performed with automatic tube current modulation... - Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases (KPC) resistanceLuke F Chen
Duke Program for Infection Prevention and Healthcare Epidemiology, Durham, NC, USA Duke Infection Control Outreach Network, Durham, NC, USA Duke University Prevention Epicenter Program, Durham, NC, USA Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, NC, USA
Infect Drug Resist 5:133-41. 2012..Thus, the emergence of KPC resistance is a major threat to global health. This article reviews the epidemiology and provides an overview of the dissemination of KPC-producing organisms... - CT mucosal window settings: a novel approach to evaluating early T-stage head and neck carcinomaJenny K Hoang
Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA
AJR Am J Roentgenol 195:1002-6. 2010.... - Methicillin-resistant Staphylococcus aureus in hospitals: time for a culture changeLuke F Chen
Med J Aust 188:62-3; author reply 63-4. 2008 - Surgical site infections after laparoscopic and open cholecystectomies in community hospitals Luke F Chen
Infect Control Hosp Epidemiol 29:92-4; author reply 94-5. 2008 - Hypovolemic shock and metabolic acidosis in a refugee secondary to O1 serotype Vibrio cholerae enteritisLuke F Chen
Monash Medical Centre, Clayton, Victoria
Commun Dis Intell 30:233-5. 2006