Research Topics
| Christopher CabellSummaryAffiliation: Duke University Medical Center Country: USA Publications
Research Grants
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Detail Information
Publications
The risk of stroke and death in patients with aortic and mitral valve endocarditisC H Cabell
Department of Medicine, Duke University School of Medicine, Duke Clinical Research Institute, Durham, NC, USA
Am Heart J 142:75-80. 2001....- Increasing rates of cardiac device infections among Medicare beneficiaries: 1990-1999Christopher H Cabell
Divisions of Division of Cardiology, Duke University Medical Center, and Duke Clinical Research Institute, Durham, NC 27715, USA
Am Heart J 147:582-6. 2004.... - Progress toward a global understanding of infective endocarditis. Lessons from the International Collaboration on EndocarditisChristopher H Cabell
Division of Cardiology, Department of Medicine, Box 3850, Duke University Medical Center, Duke Clinical Research Institute, Durham, NC 27710, USA
Cardiol Clin 21:147-58. 2003..Although many obstacles remain to be overcome, ICE has created the opportunity for a quantum leap in our knowledge of IE over the next 25 years... - Clinical utility of the Food and Drug Administration Electrocardiogram Warehouse: a paradigm for the critical pathway initiativeChristopher H Cabell
Department of Medicine, Duke University School of Medicine, Durham, NC, USA Duke Clinical Research Institute, Durham, NC 27715, USA
J Electrocardiol 38:175-9. 2005..The FDA Electrocardiogram Warehouse is 1 example where a government resource could be used by a confluence of groups to improve the science surrounding important components of the drug approval process such as cardiac safety evaluation... - Use of surgery in patients with native valve infective endocarditis: results from the International Collaboration on Endocarditis Merged DatabaseChristopher H Cabell
Duke University Medical Center, Durham, NC, USA
Am Heart J 150:1092-8. 2005..The aim of the study was to characterize patients with native valve IE relative to surgery and to determine if patients who benefit from an early surgical intervention can be identified... - Progress toward a global understanding of infective endocarditis. Early lessons from the International Collaboration on Endocarditis investigationChristopher H Cabell
Department of Medicine, Box 31020, Duke University School of Medicine, Duke Clinical Research Institute, Durham, NC 27713, USA
Infect Dis Clin North Am 16:255-72, vii. 2002..The multinational nature of the collaboration may also permit a more global view of IE and provide opportunities for studies such as randomized trials of therapeutic treatment strategies... 
Resident utilization of information technologyC H Cabell
Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA
J Gen Intern Med 16:838-44. 2001..To determine if a simple educational intervention can increase resident physician literature search activity...- Changing patient characteristics and the effect on mortality in endocarditisChristopher H Cabell
Department of Medicine, Duke University Medical Center, Box 31020, Durham, NC 27710
Arch Intern Med 162:90-4. 2002..Limited data exist on recent demographic and microbiological changes in infective endocarditis (IE) and the impact of these changes on patient survival... - Importance of echocardiography in patients with severe nonischemic heart failure: the second Prospective Randomized Amlodipine Survival Evaluation (PRAISE-2) echocardiographic studyChristopher H Cabell
Duke University School of Medicine, Durham, NC, USA
Am Heart J 147:151-7. 2004.... - Risk of endocarditis among patients with prosthetic valves and Staphylococcus aureus bacteremiaFadi El-Ahdab
Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
Am J Med 118:225-9. 2005..The mortality of prosthetic valve endocarditis is high. All patients with a prosthetic valve who develop S. aureus bacteremia should be aggressively screened and followed for endocarditis... - Early surgery in patients with infective endocarditis: a propensity score analysisOlcay Aksoy
Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, NC, USA
Clin Infect Dis 44:364-72. 2007..Largely because of these limitations, the role of surgery in long-term survival has not been adequately studied... - Influence of diabetes mellitus on the clinical manifestations and prognosis of infective endocarditis: a report from the International Collaboration on Endocarditis-Merged DatabaseWissam M Kourany
Duke University Medical Center, Durham, NC, USA
Scand J Infect Dis 38:613-9. 2006..08-2.70), especially in male patients, as diabetic males had higher mortality than non-diabetic males (OR 2.18, CI 1.08-4.35). DM is an independent predictor of in-hospital mortality among patients hospitalized with IE... - Early predictors of in-hospital death in infective endocarditisVivian H Chu
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Circulation 109:1745-9. 2004..These factors may identify those patients with IE for more aggressive treatment... - Leptotrichia endocarditis: report of two cases from the International Collaboration on Endocarditis (ICE) database and review of previous casesL B Caram
Division of Infectious Diseases, Duke University Medical Center, Box 3824, Durham, NC 27710, USA
Eur J Clin Microbiol Infect Dis 27:139-43. 2008..goodfellowii sp. nov. Both cases were identified using 16S rRNA gene sequencing. Review of the English literature revealed only two other cases of Leptotrichia sp. endocarditis... - Where's the flap?John Heitner
Division of Cardiology, New York Methodist Hospital, Brooklyn, New York 11215, USA
J Cardiovasc Magn Reson 8:549-50. 2006..Early diagnosis and prompt treatment is critical in improving the outcome of patients with IMH... - Propionibacterium endocarditis: a case series from the International Collaboration on Endocarditis Merged Database and Prospective Cohort StudyTahaniyat Lalani
Duke Clinical Research Institute, Duke University Medical Center, 2400 Pratt Street, Cube 7545, Durham, NC 27710 USA
Scand J Infect Dis 39:840-8. 2007..The clinical course is characterized by complications such as valvular dehiscence, cardiac abscesses and congestive heart failure. Treatment may require a combination of medical and surgical therapy... 
Emergence of coagulase-negative staphylococci as a cause of native valve endocarditisVivian H Chu
Duke University Medical Center, Durham, North Carolina 27710, USA
Clin Infect Dis 46:232-42. 2008..Coagulase-negative staphylococci (CoNS) are an infrequent cause of native valve endocarditis (NVE), and our understanding of NVE caused by CoNS is incomplete...- A meta-analysis of medical versus surgical therapy for Candida endocarditisWilliam J Steinbach
Division of Infectious Diseases, Department of Pediatrics, Duke University, Durham, NC 27710, USA
J Infect 51:230-47. 2005..The optimal management of Candida infective endocarditis (IE) is unknown... - The use and effect of surgical therapy for prosthetic valve infective endocarditis: a propensity analysis of a multicenter, international cohortAndrew Wang
Department of Medicine, Duke University Medical Center, Durham, NC, USA
Am Heart J 150:1086-91. 2005.... - Relation of frequency and severity of mitral regurgitation to survival among patients with left ventricular systolic dysfunction and heart failureBenjamin H Trichon
Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27715, USA
Am J Cardiol 91:538-43. 2003..MR is common in patients with LV systolic dysfunction and heart failure. After adjusting for other clinical variables, the presence of MR independently predicted worsened survival... - Staphylococcus aureus bacteremia in patients with prosthetic devices: costs and outcomesVivian H Chu
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Am J Med 118:1416. 2005..aureus bacteremia on patients with prosthetic devices. This investigation sought to define the clinical outcome, health care resource use, and infection-associated costs of S. aureus bacteremia in patients with prostheses... - Contemporary clinical profile and outcome of prosthetic valve endocarditisAndrew Wang
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
JAMA 297:1354-61. 2007..Prosthetic valve endocarditis (PVE) is associated with significant mortality and morbidity. The contemporary clinical profile and outcome of PVE are not well defined... - Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureusVance G Fowler
Duke University Medical Center, Durham, NC 27710, USA
N Engl J Med 355:653-65. 2006..Alternative therapies for Staphylococcus aureus bacteremia and endocarditis are needed... - Coagulase-negative staphylococcal prosthetic valve endocarditis--a contemporary update based on the International Collaboration on Endocarditis: prospective cohort studyV H Chu
Duke University Medical Center, Durham, NC 27710, USA
Heart 95:570-6. 2009..To describe the contemporary features of coagulase-negative staphylococcal (CoNS) prosthetic valve endocarditis (PVE)... - Clinical identifiers of complicated Staphylococcus aureus bacteremiaVance G Fowler
Division of Infectious Diseases, Duke University Medical Center, Durham, NC 27710, USA
Arch Intern Med 163:2066-72. 2003..This investigation sought to define readily available clinical characteristics that could help identify patients at risk for complicated SAB... - Repeat infective endocarditis: differentiating relapse from reinfectionVivian H Chu
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Clin Infect Dis 41:406-9. 2005..The agreement between clinical and molecular criteria was imperfect (agreement in 10 [77%] of 13 cases)... - Staphylococcus aureus bacteremia after median sternotomy: clinical utility of blood culture results in the identification of postoperative mediastinitisVance G Fowler
Division of Infectious Diseases, Duke University Medical Center, Durham, NC 27710, USA
Circulation 108:73-8. 2003..Mediastinitis is a complication of coronary artery bypass graft surgery (CABG) that can be difficult to diagnose. This study evaluated the utility of blood culture results in identifying patients with mediastinitis... - Survival after coronary revascularization, with and without mitral valve surgery, in patients with ischemic mitral regurgitationBenjamin H Trichon
Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
Circulation 108:II103-10. 2003.... - Novel approaches to clinical trials: device-related infectionsRobert M Califf
Division of Cardiology, Duke University Medical Center and the Duke Clinical Research Institute, Durham, NC 27715, USA
Am Heart J 147:599-604. 2004..The purpose of this manuscript is to discuss issues about the design of studies and their organization... - Usefulness of myocardial viability or ischemia in predicting long-term survival for patients with severe left ventricular dysfunction undergoing revascularizationLawrence Liao
Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, NC 27710, USA
Am J Cardiol 93:1275-9. 2004..At a mean follow-up of 27 months, patients with viable myocardium who underwent revascularization had a significant survival advantage over all other patients (2-year survival 83.5% vs 57.2%, p = 0.0037)... - Candida endocarditis: contemporary cases from the International Collaboration of Infectious Endocarditis Merged Database (ICE-mD)Daniel K Benjamin
Department of Pediatrics, Duke University, Durham, NC, USA
Scand J Infect Dis 36:453-5. 2004..We evaluated 16 patients with Candida IE nested within a cohort of 2,022 patients with IE. Prosthetic valve IE was more common in patients with Candida (50% vs 17%); mortality was 37% for patients with Candida... - Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and low-level in vitro resistance to thrombin-induced platelet microbicidal proteinVance G Fowler
Department of Medicine, Division of Infectious Diseases, Duke University Medical Center, Durham, NC 27710, USA
J Infect Dis 190:1140-9. 2004..This investigation examined potential associations between PB with key clinical features and several in vitro bacterial genotypic and phenotypic characteristics, in isolates from 1 institution... - Native valve endocarditis due to coagulase-negative staphylococci: report of 99 episodes from the International Collaboration on Endocarditis Merged DatabaseVivian H Chu
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Clin Infect Dis 39:1527-30. 2004..These results emphasize the importance of CoNS as a cause of NVE and the potential for serious complications with this infection... - Venous thrombosis in patients with short- and long-term central venous catheter-associated Staphylococcus aureus bacteremiaAnna Lisa Crowley
Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC, USA
Crit Care Med 36:385-90. 2008.... - Aortic coarctation endarteritis in an adult: case report with cardiovascular magnetic resonance imaging findings and review of the literatureAlbert M L Anderson
Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
Clin Infect Dis 40:e28-31. 2005..Diagnosis is critically important given the risk of rupture. Cardiovascular magnetic resonance imaging can be helpful in management... - Telavancin versus standard therapy for treatment of complicated skin and soft-tissue infections due to gram-positive bacteriaMartin E Stryjewski
Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, USA
Clin Infect Dis 40:1601-7. 2005..CONCLUSION: Clinical and microbiological results of this study support the further development of telavancin, especially for treatment of infection due to MRSA... - Staphylococcus aureus endocarditis: a consequence of medical progressVance G Fowler
Duke University Medical Center, Durham, NC 27710, USA
JAMA 293:3012-21. 2005..The global significance of infective endocarditis (IE) caused by Staphylococcus aureus is unknown... - Non-HACEK gram-negative bacillus endocarditisSusan Morpeth
Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina 27710, USA
Ann Intern Med 147:829-35. 2007.... - Update on infective endocarditisThomas M Bashore
Duke University Medical Center, USA
Curr Probl Cardiol 31:274-352. 2006.... - The relationship between the initiation of antimicrobial therapy and the incidence of stroke in infective endocarditis: an analysis from the ICE Prospective Cohort Study (ICE-PCS)Stuart A Dickerman
Department of Medicine, New York University School of Medicine, New York, NY, USA
Am Heart J 154:1086-94. 2007.... - Cardiology patient page. Bacterial endocarditis: the disease, treatment, and preventionChristopher H Cabell
Duke University School of Medicine and Duke Clinical Research Institute, Durham, NC, USA
Circulation 107:e185-7. 2003 - Gender differences in infective endocarditis: pre- and co-morbid conditions lead to different management and outcomes in female patientsOlcay Aksoy
Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
Scand J Infect Dis 39:101-7. 2007.... - Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the CouWalter Wilson
Mayo Clinic, Rochester, MN, USA
J Am Dent Assoc 138:739-45, 747-60. 2007..The purpose of this statement is to update the recommendations by the American Heart Association (AHA) for the prevention of infective endocarditis, which were last published in 1997... - Relation of troponin elevation to outcome in patients with infective endocarditisJonathan B Purcell
University of Texas Southwestern Medical Center, Dallas, Texas, USA
Am J Cardiol 101:1479-81. 2008..05 for each). In conclusion, elevated cTnI was associated with the composite of death, abscess, and central nervous system events (p <0.001)... - Periannular complications in infective endocarditis involving native aortic valvesIgnasi Anguera
Corporacio Sanitaria Parc Tauli-Hospital de Sabadell, Sabadell, Spain
Am J Cardiol 98:1254-60. 2006..Despite these higher rates of complications, fistulous tract formation in the current era of IE is not an independent risk factor for mortality... - Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the CouWalter Wilson
J Am Dent Assoc 139:3S-24S. 2008..These changes are intended to define more clearly when IE prophylaxis is or is not recommended and to provide more uniform and consistent global recommendations... - Periannular complications in infective endocarditis involving prosthetic aortic valvesIgnasi Anguera
Corporacio Sanitaria Parc Tauli-Hospital de Sabadell, Sabadell, Spain
Am J Cardiol 98:1261-8. 2006..Despite the frequent complications, fistulous tract formation in the current era of infective endocarditis is not an independent risk factor for mortality... - Aorto-cavitary fistulous tract formation in infective endocarditis: clinical and echocardiographic features of 76 cases and risk factors for mortalityIgnasi Anguera
Corporacio Sanitaria Parc Tauli-Hospital de Sabadell, Sabadell, Spain
Eur Heart J 26:288-97. 2005..Prosthetic IE, urgent surgery, and the development of HF identify the subgroup of patients with IE and ACF that have significantly increased risk of in-hospital death... - Clinical characteristics and outcome of aortic endocarditis with periannular abscess in the International Collaboration on Endocarditis Merged DatabaseIgnasi Anguera
, Hospital de Sabadell, University of Barcelona, Barcelona, Spain
Am J Cardiol 96:976-81. 2005..S. aureus infection is an independent prognostic factor for mortality in patients who have abscess formation... - Staphylococcus aureus native valve infective endocarditis: report of 566 episodes from the International Collaboration on Endocarditis Merged DatabaseJose M Miro
Hospital Clinic Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
Clin Infect Dis 41:507-14. 2005..Staphylococcus aureus native valve infective endocarditis (SA-NVIE) is not completely understood. The objective of this investigation was to describe the characteristics of a large, international cohort of patients with SA-NVIE... - Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the CoWalter Wilson
Mayo Clinic, USA
Circulation 116:1736-54. 2007..The purpose of this statement is to update the recommendations by the American Heart Association (AHA) for the prevention of infective endocarditis that were last published in 1997... - Vegetations in endocarditis: big is bad, but is there more to it?Christopher H Cabell
Am Heart J 146:189-90. 2003
Research Grants
- Pathophysiology/Clinical Outcomes/Patients/EndocarditisChristopher Cabell; Fiscal Year: 2005..The findings of this study have implications not only for clinical care but will also provide a foundation of knowledge and network of investigators from which subsequent randomized trials can be conducted. ..