A Wesley Burks

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint Food allergy
    Wesley Burks
    Pediatric Allergy and Immunology, Duke University Medical Center, Durham, NC 27710, USA
    Mol Nutr Food Res 50:595-603. 2006
  2. doi request reprint Food allergies and hypersensitivity: a review of pharmacotherapy and therapeutic strategies
    Wesley Burks
    Duke University Medical Center, Pediatric Allergy and Immunology, Box 3530, Durham, NC 27710, USA
    Expert Opin Pharmacother 9:1145-52. 2008
  3. doi request reprint Peanut allergy
    A Wesley Burks
    Pediatric Allergy and Immunology, Duke University Medical Center, Durham, NC 27710, USA
    Lancet 371:1538-46. 2008
  4. doi request reprint Oral tolerance, food allergy, and immunotherapy: implications for future treatment
    A Wesley Burks
    Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, NC 27710, USA
    J Allergy Clin Immunol 121:1344-50. 2008
  5. pmc NIAID-sponsored 2010 guidelines for managing food allergy: applications in the pediatric population
    A Wesley Burks
    Division of Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    Pediatrics 128:955-65. 2011
  6. pmc The natural history of milk allergy in an observational cohort
    Robert A Wood
    Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Allergy Clin Immunol 131:805-12. 2013
  7. pmc Sublingual immunotherapy for peanut allergy: a randomized, double-blind, placebo-controlled multicenter trial
    David M Fleischer
    Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA
    J Allergy Clin Immunol 131:119-27.e1-7. 2013
  8. pmc Clinical efficacy and immune regulation with peanut oral immunotherapy
    Stacie M Jones
    Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children s Hospital, Little Rock, Ark, USA
    J Allergy Clin Immunol 124:292-300, 300.e1-97. 2009
  9. pmc Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergy
    Scott H Sicherer
    Elliot and Roslyn Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    J Allergy Clin Immunol 125:1077-1083.e8. 2010
  10. pmc Peanut oral immunotherapy modifies IgE and IgG4 responses to major peanut allergens
    Brian P Vickery
    Division of Pediatric Allergy and Immunology, Duke University School of Medicine, Durham, NC 27599, USA
    J Allergy Clin Immunol 131:128-34.e1-3. 2013

Research Grants

Collaborators

Detail Information

Publications59

  1. ncbi request reprint Food allergy
    Wesley Burks
    Pediatric Allergy and Immunology, Duke University Medical Center, Durham, NC 27710, USA
    Mol Nutr Food Res 50:595-603. 2006
    ..This article reviews the classification of food allergies, their prevalence, pathophysiology, diagnosis, treatment and prognosis...
  2. doi request reprint Food allergies and hypersensitivity: a review of pharmacotherapy and therapeutic strategies
    Wesley Burks
    Duke University Medical Center, Pediatric Allergy and Immunology, Box 3530, Durham, NC 27710, USA
    Expert Opin Pharmacother 9:1145-52. 2008
    ..At present, the avoidance of the allergenic food is the only method of preventing further reactions for allergic patients...
  3. doi request reprint Peanut allergy
    A Wesley Burks
    Pediatric Allergy and Immunology, Duke University Medical Center, Durham, NC 27710, USA
    Lancet 371:1538-46. 2008
    ..This Seminar looks at the changing epidemiology of this allergy--and theories as to the rise in prevalence, diagnosis, and management of the allergy, and potential new treatments and prevention strategies under development...
  4. doi request reprint Oral tolerance, food allergy, and immunotherapy: implications for future treatment
    A Wesley Burks
    Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, NC 27710, USA
    J Allergy Clin Immunol 121:1344-50. 2008
    ..In this article we review the mechanisms of tolerance, discuss aberrations in oral tolerance, and provide information on novel prevention and treatment paradigms for food allergy...
  5. pmc NIAID-sponsored 2010 guidelines for managing food allergy: applications in the pediatric population
    A Wesley Burks
    Division of Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    Pediatrics 128:955-65. 2011
    ..To focus on those concerns, we describe here the guidelines most pertinent to the pediatric population...
  6. pmc The natural history of milk allergy in an observational cohort
    Robert A Wood
    Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Allergy Clin Immunol 131:805-12. 2013
    ..There are few studies on the natural history of milk allergy. Most are single-site and not longitudinal, and these have not identified a means for early prediction of outcomes...
  7. pmc Sublingual immunotherapy for peanut allergy: a randomized, double-blind, placebo-controlled multicenter trial
    David M Fleischer
    Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA
    J Allergy Clin Immunol 131:119-27.e1-7. 2013
    ..There are presently no available therapeutic options for patients with peanut allergy...
  8. pmc Clinical efficacy and immune regulation with peanut oral immunotherapy
    Stacie M Jones
    Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children s Hospital, Little Rock, Ark, USA
    J Allergy Clin Immunol 124:292-300, 300.e1-97. 2009
    ..Oral immunotherapy (OIT) has been thought to induce clinical desensitization to allergenic foods, but trials coupling the clinical response and immunologic effects of peanut OIT have not been reported...
  9. pmc Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergy
    Scott H Sicherer
    Elliot and Roslyn Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    J Allergy Clin Immunol 125:1077-1083.e8. 2010
    ..Immune features of infants with food allergy have not been delineated...
  10. pmc Peanut oral immunotherapy modifies IgE and IgG4 responses to major peanut allergens
    Brian P Vickery
    Division of Pediatric Allergy and Immunology, Duke University School of Medicine, Durham, NC 27599, USA
    J Allergy Clin Immunol 131:128-34.e1-3. 2013
    ..Patients with peanut allergy have highly stable pathologic antibody repertoires to the immunodominant B-cell epitopes of the major peanut allergens Ara h 1 to 3...
  11. pmc The safety and efficacy of sublingual and oral immunotherapy for milk allergy
    Corinne A Keet
    Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Allergy Clin Immunol 129:448-55, 455.e1-5. 2012
    ..Oral immunotherapy (OIT) and sublingual immunotherapy (SLIT) are potential therapies for food allergy, but the optimal method of administration, mechanism of action, and duration of response remain unknown...
  12. ncbi request reprint Egg oral immunotherapy in nonanaphylactic children with egg allergy
    Ariana D Buchanan
    Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    J Allergy Clin Immunol 119:199-205. 2007
    ..There is no current active treatment for food allergy. Traditional injection immunotherapy has been proved unsafe, and thus there is a need for other forms of immunotherapy...
  13. doi request reprint In vivo and T cell cross-reactivity between walnut, cashew and peanut
    Michael Kulis
    Department of Pediatrics, Division of Pediatric Allergy and Immunology, Duke University Medical Center, Durham, NC 27710, USA
    Int Arch Allergy Immunol 148:109-17. 2009
    ..Using a mouse model in which the sensitizing nuts are controlled may provide novel methods to investigate in vivo and T cell cross-reactivity...
  14. pmc Individualized IgE-based dosing of egg oral immunotherapy and the development of tolerance
    Brian P Vickery
    Division of Pediatric Allergy and Immunology, Duke University School of Medicine, Durham, North Carolina 27710, USA
    Ann Allergy Asthma Immunol 105:444-50. 2010
    ..Hen's egg allergy is among the most common food allergies in childhood and predicts later development of allergic disease. The optimal efficacy and mechanism(s) of egg allergen immunotherapy are poorly understood...
  15. pmc Oral immunotherapy for treatment of egg allergy in children
    A Wesley Burks
    Department of Pediatrics, Duke University Medical Center, Durham, NC 27599 7220, USA
    N Engl J Med 367:233-43. 2012
    ..For egg allergy, dietary avoidance is the only currently approved treatment. We evaluated oral immunotherapy using egg-white powder for the treatment of children with egg allergy...
  16. pmc Safety of a peanut oral immunotherapy protocol in children with peanut allergy
    Alison M Hofmann
    Division of Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    J Allergy Clin Immunol 124:286-91, 291.e1-6. 2009
    ..Oral immunotherapy (OIT) offers a promising therapeutic option for peanut allergy. Given that during OIT an allergic patient ingests an allergen that could potentially cause a serious reaction, the safety of OIT is of particular concern...
  17. doi request reprint Pioneering immunotherapy for food allergy: clinical outcomes and modulation of the immune response
    Mike Kulis
    Department of Pediatric Allergy and Immunology, Duke University Medical Center, DUMC Box 2644, Durham, NC 27710, USA
    Immunol Res 49:216-26. 2011
    ..Development of these immunotherapy strategies has generated much excitement in the food allergy community; however, further studies are needed before these approaches are ready for clinical use...
  18. ncbi request reprint Soy immunotherapy for peanut-allergic mice: modulation of the peanut-allergic response
    Laurent Pons
    Department of Pediatrics, Division of Pediatric Allergy and Immunology, Duke University Medical Center, Durham, NC 27710, USA
    J Allergy Clin Immunol 114:915-21. 2004
    ..So far, peanut-specific IT has been unsuccessful because of the side effects of therapy. Soybean seed storage proteins share significant homology with the respective peanut allergens...
  19. ncbi request reprint Peanut allergy: recurrence and its management
    David M Fleischer
    Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Baltimore, MD 21287, USA
    J Allergy Clin Immunol 114:1195-201. 2004
    ..Although peanut allergy may recur, the frequency with which this occurs is unknown...
  20. doi request reprint Role of tolerance in the development of eosinophilic gastrointestinal diseases
    Pooja Varshney
    Division of Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Box 2898, Durham, NC 27710, USA
    Immunol Allergy Clin North Am 29:179-87, xiii. 2009
    ..Further study to clarify the role of tolerance in the development of eosinophilic gastrointestinal diseases can help identify potential prevention strategies and therapeutic targets...
  21. ncbi request reprint Animal models of food allergy
    Ricki M Helm
    ACHRI UAMS, Department of Pediatrics, Little Rock, Arkansas 72202, USA
    Curr Opin Allergy Clin Immunol 2:541-6. 2002
    ..The focus of this review will be on recent animal models of food allergy. Animal models are being used to investigate underlying mechanisms of IgE-mediated disease and for prophylactic/intervention therapies to treat allergic disease...
  22. pmc A randomized controlled study of peanut oral immunotherapy: clinical desensitization and modulation of the allergic response
    Pooja Varshney
    Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, NC, USA
    J Allergy Clin Immunol 127:654-60. 2011
    ..Open-label oral immunotherapy (OIT) protocols have been used to treat small numbers of patients with peanut allergy. Peanut OIT has not been evaluated in double-blind, placebo-controlled trials...
  23. ncbi request reprint The major glycoprotein allergen from Arachis hypogaea, Ara h 1, is a ligand of dendritic cell-specific ICAM-grabbing nonintegrin and acts as a Th2 adjuvant in vitro
    Wayne G Shreffler
    Jaffe Food Allergy Institute, Department of Pediatrics, Division of Allergy and Immunology, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Immunol 177:3677-85. 2006
    ..Both PNAg and purified Ara h 1 induced Erk 1/2 phosphorylation of MDDCs, consistent with previous reports on the effect of Th2 adjuvants on DCs...
  24. doi request reprint Pepsinized cashew proteins are hypoallergenic and immunogenic and provide effective immunotherapy in mice with cashew allergy
    Mike Kulis
    Department of Pediatric Allergy and Immunology, Duke University Medical Center, Durham, NC 27710, USA
    J Allergy Clin Immunol 130:716-23. 2012
    ..IgE-mediated allergic reactions to cashews and other nuts can trigger life-threatening anaphylaxis. Proactive therapies to decrease reaction severity do not exist...
  25. ncbi request reprint Engineered recombinant peanut protein and heat-killed Listeria monocytogenes coadministration protects against peanut-induced anaphylaxis in a murine model
    Xiu Min Li
    Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Immunol 170:3289-95. 2003
    ..These results show that immunotherapy with modified PN proteins and HKLM is effective for treating PN allergy in this model, and may be a potential approach for treating PNA...
  26. pmc Mechanisms of immune tolerance relevant to food allergy
    Brian P Vickery
    Division of Pediatric Allergy and Immunology, Duke University School of Medicine, Durham, NC 27710, USA
    J Allergy Clin Immunol 127:576-84; quiz 585-6. 2011
    ..Food allergy is among the clinical disorders that occur from a failure of this system, and therapies that seek to re-establish tolerance are currently under investigation...
  27. pmc Sublingual immunotherapy for peanut allergy: clinical and immunologic evidence of desensitization
    Edwin H Kim
    Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, NC 27710, USA
    J Allergy Clin Immunol 127:640-6.e1. 2011
    ..There are no treatments currently available for peanut allergy. Sublingual immunotherapy (SLIT) is a novel approach to the treatment of peanut allergy...
  28. ncbi request reprint Microarray immunoassay: association of clinical history, in vitro IgE function, and heterogeneity of allergenic peanut epitopes
    Wayne G Shreffler
    Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai Medical Center, Box 1198, One Gustave L Levy Place, New York, NY 10029, USA
    J Allergy Clin Immunol 113:776-82. 2004
    ..Mapping of large numbers of epitopes by using individual patient sera has been impractical with current techniques...
  29. ncbi request reprint Pollen food syndrome: update on the allergens
    Alison Hofmann
    Division of Pediatric Allergy and Immunology, Duke University Medical Center, DUMC Box 2898, Durham, NC 27110, USA
    Curr Allergy Asthma Rep 8:413-7. 2008
    ..Immunotherapy has been studied as a treatment for pollen food syndrome, with highly variable results...
  30. doi request reprint ICON: food allergy
    A Wesley Burks
    Department of Pediatrics, University of North Carolina, Chapel Hill, NC, USA
    J Allergy Clin Immunol 129:906-20. 2012
    ..An author group was formed to describe the natural history, prevalence, diagnosis, and treatment of food allergies in the context of the global community...
  31. pmc Pathophysiology of food allergy
    Brian P Vickery
    Division of Pediatric Allergy and Immunology, Department of Pediatrics, Duke University School of Medicine, Box 2644, Durham, NC 27710, USA
    Pediatr Clin North Am 58:363-76, ix-x. 2011
    ..Adjacent IgE molecules bound to the surface of the mast cell become cross-linked, causing mast cell degranulation and release of powerful vasoactive compounds that cause allergic symptoms...
  32. doi request reprint Immunotherapy in the treatment of food allergy: focus on oral tolerance
    Brian P Vickery
    Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Curr Opin Allergy Clin Immunol 9:364-70. 2009
    ..Here we discuss the relationship of food allergy to oral tolerance and review recent oral tolerance studies, focusing on the mechanistic role of antigen presenting cells and the generation of regulatory T cells in mice and humans...
  33. pmc A randomized, double-blind, placebo-controlled study of milk oral immunotherapy for cow's milk allergy
    Justin M Skripak
    Department of Pediatrics, Division of Allergy and Immunology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Allergy Clin Immunol 122:1154-60. 2008
    ..Orally administered, food-specific immunotherapy appears effective in desensitizing and potentially permanently tolerizing allergic individuals...
  34. pmc Synergistic control of T cell development and tumor suppression by diacylglycerol kinase alpha and zeta
    Rishu Guo
    Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 105:11909-14. 2008
    ....
  35. pmc Oral desensitization for food hypersensitivity
    Michael H Land
    Division of Pediatric Allergy and Immunology, Duke University Medical Center, Medical Sciences Research Building I, DUMC Box 2644, Durham, NC 27710, USA
    Immunol Allergy Clin North Am 31:367-76, xi. 2011
    ..This article examines the mechanisms of oral tolerance and the breakdown that leads to food allergy, as well as the history and current state of oral and sublingual immunotherapy development...
  36. ncbi request reprint Peanut allergenicity
    Amy M Scurlock
    Division of Pediatric Allergy and Immunology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ann Allergy Asthma Immunol 93:S12-8. 2004
    ....
  37. ncbi request reprint Food allergies: prevalence, molecular characterization, and treatment/prevention strategies
    Laurie A Lee
    Pediatric Allergy and Immunology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Annu Rev Nutr 26:539-65. 2006
    ..Various immunotherapy approaches are under investigation to alleviate or prevent food-induced reactions in those who have persistent food allergies...
  38. ncbi request reprint The natural progression of peanut allergy: Resolution and the possibility of recurrence
    David M Fleischer
    Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Allergy Clin Immunol 112:183-9. 2003
    ..It was once thought that peanut allergy is a lifelong problem. We previously reported that about 20% of children outgrow their peanut allergy and that more than 60% of patients with a peanut-IgE level of 5 or less passed an oral challenge...
  39. doi request reprint Oral immunotherapy for food allergy
    Brian P Vickery
    Division of Pediatric Allergy and Immunology, Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina 27710, USA
    Curr Opin Pediatr 22:765-70. 2010
    ..Food allergy is a difficult clinical problem for which no disease-modifying therapy currently exists...
  40. pmc Future therapies for food allergy
    Laurie M McWilliams
    Department of Pediatrics, Duke University, Durham, NC USA
    Hum Vaccin Immunother 8:1479-84. 2012
    ..Although none of these treatments are ready for clinical use, these therapeutic strategies present promising options for the future of food allergy...
  41. ncbi request reprint Food allergy in children
    Amy M Scurlock
    Pediatric Allergy and Immunology, University of Arkansas for Medical Sciences, 800 Marshall Street, Little Rock, AR 72207, USA
    Immunol Allergy Clin North Am 25:369-88, vii-viii. 2005
    ..This article examines adverse food reactions that are IgE-mediated, non-IgE-mediated, and those entities that have characteristics of both...
  42. ncbi request reprint Towards immunotherapy for peanut allergy
    Laurent Pons
    Pediatric Allergy and Immunology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Curr Opin Allergy Clin Immunol 5:558-62. 2005
    ..Based on extensive characterization of food allergens and a better understanding of the immunological mechanisms underlying allergic disease, promising therapeutic modalities for food allergy treatment and prevention are being developed...
  43. doi request reprint Type B CpG oligodeoxynucleotides induce Th1 responses to peanut antigens: modulation of sensitization and utility in a truncated immunotherapy regimen in mice
    Mike Kulis
    Department of Pediatric Allergy and Immunology, Duke University Medical Center, Durham, NC 27599, USA
    Mol Nutr Food Res 57:906-15. 2013
    ..Peanut allergy stems from a Th2-biased immune response to peanut allergens leading to IgE production and allergic reactions upon ingestion...
  44. doi request reprint The changing CARE for patients with food allergy
    Stacie M Jones
    Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children s Hospital, Little Rock, Arkansas, USA
    J Allergy Clin Immunol 131:3-11; quiz 12-3. 2013
    ..This review will focus on the concepts of a holistic approach to food allergy that is working to improve CARE for subjects with food allergy, including new advances in clinical care, advocacy, research, and education...
  45. pmc The future of food allergy therapeutics
    Michele Henson
    Duke University Medical Center, Durham, NC, USA
    Semin Immunopathol 34:703-14. 2012
    ..The array of treatment modalities currently being investigated increases the likelihood of finding one or more effective therapies for the treatment of food allergy...
  46. ncbi request reprint Oral allergy syndrome
    Scott Nash
    Duke University Medical Center, Box 2644, Durham, NC 27710, USA
    Curr Allergy Asthma Rep 7:1-2. 2007
  47. pmc Diacylglycerol kinase zeta regulates microbial recognition and host resistance to Toxoplasma gondii
    Cheng hu Liu
    Department of Pediatrics Allergy and Immunology, Duke University Medical Center, Durham, NC 27710, USA
    J Exp Med 204:781-92. 2007
    ....
  48. ncbi request reprint New insights into diagnosis and treatment of peanut food allergy
    Laurie A Lee
    Pediatric Allergy and Immunology, Duke University Medical Center, Durham, USA
    Front Biosci (Landmark Ed) 14:3361-71. 2009
    ..Because inadvertent ingestion of peanut often leads to life threatening reactions and peanut allergy is often long-lived, many investigators are focusing on decreasing clinical reactivity after peanut allergy is established...
  49. ncbi request reprint A neonatal swine model for peanut allergy
    Ricki M Helm
    Division of Allergy Immunology, Department of Pediatrics, Arkansas Children s Hospital Research Institute, University of Arkansas for Medical Sciences, Little Rock 72201, USA
    J Allergy Clin Immunol 109:136-42. 2002
    ..As yet, no animal model has been developed that will completely mimic the physical, immunologic, and histologic features of food allergy...
  50. ncbi request reprint Omalizumab : other indications and unanswered questions
    Vaishali S Mankad
    Division of Pediatric Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC, USA
    Clin Rev Allergy Immunol 29:17-30. 2005
    ....
  51. doi request reprint Food allergy and asthma
    J Andrew Bird
    Department of Pediatrics, Duke University Medical Center, North Carolina 27710, USA
    Prim Care Respir J 18:258-65. 2009
    ....
  52. ncbi request reprint Allergen immunotherapy for allergic rhinitis
    Mary Dell Railey
    Pediatric Allergy and Immunology, Duke UniversityMedical Center, Durham, NC 27710, USA
    Curr Allergy Asthma Rep 8:1-3. 2008
  53. ncbi request reprint Novel treatments for food allergy
    Laurent Pons
    Pediatric Allergy and Immunology, Duke University Medical Center, Box 3530, Durham, NC 27710, USA
    Expert Opin Investig Drugs 14:829-34. 2005
    ..It is the combination of these different approaches that would probably offer the best treatment option for food-allergic patients in a not too distant future...
  54. doi request reprint Update on allergy immunotherapy: American Academy of Allergy, Asthma & Immunology/European Academy of Allergy and Clinical Immunology/PRACTALL consensus report
    A Wesley Burks
    Department of Pediatrics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599 7220, USA
    J Allergy Clin Immunol 131:1288-96.e3. 2013
    ..This resulting report is endorsed by both academies...
  55. pmc Food allergy: present and future management
    Ananth Thyagarajan
    From the Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, NC
    World Allergy Organ J 2:282-8. 2009
    ..Allergen nonspecific methods act via a more global TH2 suppressive mechanism and may be useful for those patients with multiple food allergies...
  56. ncbi request reprint Occupational asthma symptoms and respiratory function among aerial pesticide applicators
    Stacie M Jones
    Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas 72202, USA
    Am J Ind Med 43:407-17. 2003
    ..The goal of this investigation was to determine the effect of pesticide exposure on respiratory symptoms and lung function in workers with occupational exposure to pesticides...
  57. ncbi request reprint Current developments in peanut allergy
    Kricia Palmer
    Duke University Medical Center, Pediatric Allergy and Immunology, Durham, New Carolina 27710, USA
    Curr Opin Allergy Clin Immunol 6:202-6. 2006
    ..Our objective is to highlight recent advances in the immunology and treatment of peanut allergy...
  58. ncbi request reprint Food allergens
    Wesley Burks
    Duke University Medical Center, Durham, North Carolina, USA
    Clin Allergy Immunol 18:319-37. 2004
  59. ncbi request reprint Persistent protective effect of heat-killed Escherichia coli producing "engineered," recombinant peanut proteins in a murine model of peanut allergy
    Xiu Min Li
    Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    J Allergy Clin Immunol 112:159-67. 2003
    ..Peanut allergy (PNA) is a life-threatening food allergy for which there is no definitive treatment...

Research Grants16

  1. Sublingual Immunotherapy for Peanut Allergy
    ARVIL WESLEY BURKS; Fiscal Year: 2010
    ..The development of a treatment and understanding the mechanism of how it works is important for the future treatment of patients with food allergy. ..
  2. Sublingual Immunotherapy for Peanut Allergy
    ARVIL BURKS; Fiscal Year: 2009
    ..The development of a treatment and understanding the mechanism of how it works is important for the future treatment of patients with food allergy. ..
  3. Understanding the Mechanism of Mucosal Immunotherapy
    ARVIL BURKS; Fiscal Year: 2007
    ..The long-term goal of the study is to utilize egg and peanut OIT for the induction of clinical and immunologic tolerance to the allergen that will be sustained once the protocol is completed. ..
  4. Immunotherapy for Peanut Allergy
    ARVIL BURKS; Fiscal Year: 2007
    ..The significance of this proposal is that if peanut SLIT in peanut allergic patients is effective, the treatment would provide an immediate therapeutic option for patients. ..
  5. RESEARCH TRAINING IN ALLERGY AND CLINICAL IMMUNOLOGY
    ARVIL BURKS; Fiscal Year: 2007
    ....
  6. ARKANSAS CHILDREN HOSP RES INST CONSTR: PAIN OSTEOGENESIS
    ARVIL BURKS; Fiscal Year: 2002
    ..The planned facility expansion does not replace existing ACHRI facilities and will correct deficiencies and limitations in the present facilities. ..
  7. Soy Immunotherapy for Patients with Peanut Anaphylaxis
    ARVIL BURKS; Fiscal Year: 2004
    ..If soybean IT in peanut allergic patients is effective, the treatment would provide an immediate therapeutic option. ..
  8. IMMUNOTHERAPY FOR PATIENTS WITH PEANUT ANAPHYLAXIS
    ARVIL BURKS; Fiscal Year: 2003
    ..abstract_text> ..
  9. EXTRAMURAL RES FACILITIES CONSTR PROJ
    ARVIL BURKS; Fiscal Year: 2002
    ....
  10. Understanding the Mechanism of Mucosal Immunotherapy
    ARVIL WESLEY BURKS; Fiscal Year: 2010
    ..The long-term goal of the study is to utilize egg and peanut OIT for the induction of clinical and immunologic tolerance to the allergen that will be sustained once the protocol is completed. ..