B H Brummett

..A common 44-base pair deletion (s allele) polymorphism in the 5-HTTLPR is associated with reduced 5HTT transcription efficiency and 5HT uptake in vitro...

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..On the basis of prior findings, we hypothesized that the more transcriptionally active allele variants would be associated with increased CVR...

..The present results extend previous work regarding the moderating effect of income to a sample of relatively high education and income level...

..We attempted to replicate findings suggesting a positive relation between the short allele variant of 5-HTTLPR and Neuroticism, and a negative association between the short allele variant and Agreeableness...

..This study aimed to examine demographic, psychosocial, and clinical variables as predictors of smoking cessation in patients with coronary artery disease...

..Social isolation has been linked to poor survival in patients with coronary artery disease (CAD). Few studies have closely examined the psychosocial characteristics of CAD patients who lack social contact...

..Findings from two independent samples suggest that the association of 5-HTTLPR with depression varies according to gender and stressful life events...

..The present study also used a multi-measure approach to assess both depressive symptomatology and social support...

..For men, however, spouse's hostility was not related to symptoms of depression. These findings highlight the need to study psychosocial risk factors in social units and have potential implications for intervention...

..These findings also have implications for the design and interpretation of psychosocial interventions...

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..This investigation divided depressive symptoms into groups to assess their relative effectiveness in predicting survival...

..This study examined the descriptive relationship of self-rated health (SRH) with various psychosocial measures, sociodemographic variables, coronary artery disease (CAD) diagnostic/clinical measures, and medically abstracted comorbidities...

..These individuals may subsequently require the greatest degree of care and potentially benefit most from intervention...

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..To conclude, all the parameters such as race, living arrangements, and the components of depression need to be taken into account to understand the impact of caregiving on the emotional health of caregivers...

..We found the long allele associated with larger CVR to mental stress in a preliminary study of 54 normal volunteers...

..Allelic variation in MAOA-uVNTR has been associated with body mass index (BMI). We extended previous work by examining relations among this polymorphism and serum lipid levels...

..08-.09). Openness was associated with healthy eating habits--findings that may affect disease prevention during, midlife...

..Remaining personality domains were not related to prolactin levels. Findings add to literature suggesting the serotonin system functions differently, in important ways, in males and females...

..013), and trended towards predicting anger-hostility (P = .084). Males in the HiHi group had greater increases in negative affect during infusion, compared to all groups except LoLo females, who also showed increased negative affect...

..Lower levels of PE during follow-up were also related to increasing decline in function but only in men. Thus, our findings indicate that PE is associated with less decline in functional status following hospitalization for CAD...

..HOST has been associated with abnormalities in glucose metabolism. Prior studies suggested that this association may be more prevalent in women and in African American (AA) individuals...

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..5/4 repeats) (cortisol p<.043). Individuals with less active MAOA-uVNTR alleles who are under chronic stress may be at increased risk for exhaustion of the HPA response to such stress...

..Current evidence supports the hypothesis that gene-environment interactions modulate serum lipid concentrations...

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..Depressive symptoms moderate the effect of trait hostility on circulating levels of CRP and IL-6...

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..An extensive body of research has demonstrated an association between negative affective states and health outcomes. Positive emotions may also influence physical health, however, their examination has received far less attention...

..After controlling for disease severity, there was a significant interaction between age and hostility. Hostility was significantly associated with poorer survival but only in younger (<61.2 years) patients...

..To examine hostility measured in college and patterns of change in hostility from college to midlife as predictors of high health-related risk later in midlife...

..Results indicated that smoking and/or sedentary behavior may partially mediate the relation between depressive symptoms and mortality. No evidence for moderation was found...

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..The structural model accounted for approximately 43% of the variance in sleep quality. The present findings may be useful in the development of successful sleep interventions for caregivers...

..To examine a measure of explanatory style, the Optimism-Pessimism (PSM) scale derived from college-entry Minnesota Multiphasic Personality Inventory scores, as a predictor of all-cause mortality...

..MAOA-uVNTR genotype has been associated with both psychological and physical measures...

..This study examined the associations of depressive symptoms with glucose concentrations and morning cortisol levels in 665 African-American and 4,216 Caucasian Vietnam-era veterans...

..This study examined the ability of the total CMHS and an abbreviated form of the CMHS (ACM) to predict survival in a sample of patients with documented coronary artery disease (CAD) with increased statistical power...

..The facets within each domain demonstrated different patterns of associations with the well-being measures, indicating that facet-level assessments yield additional information...

..149). Positive affect was inversely related to the increase in cortisol 30 min post awakening (p=.042), and unrelated to the evening decline in cortisol levels (p=.174). Positive emotions may be relevant to good health...

..Our objective in this study was to explore the effects of caregiver characteristics on cultural reasons given for providing care to dependent elderly family members...