Jane Blood-Siegfried

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint Sudden infant death syndrome: a toxic response
    J Blood-Siegfried
    Duke University, School of Nursing, PO Box 3322, Durham, NC 27710, USA
    AACN Clin Issues 11:300-8. 2000
  2. ncbi request reprint Synergistic effect of influenza a virus on endotoxin-induced mortality in rat pups: a potential model for sudden infant death syndrome
    Jane Blood-Siegfried
    Environmental Immunology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Pediatr Res 52:481-90. 2002
  3. ncbi request reprint Animal models of sudden unexplained death
    Jane Blood-Siegfried
    School of Nursing, Duke University, Box 3322, Durham, NC 27707, USA
    FEMS Immunol Med Microbiol 42:34-41. 2004
  4. ncbi request reprint Alteration in regulation of inflammatory response to influenza a virus and endotoxin in suckling rat pups: a potential relationship to sudden infant death syndrome
    Jane Blood-Siegfried
    Environmental Immunology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    FEMS Immunol Med Microbiol 42:85-93. 2004
  5. pmc Evidence for infection, inflammation and shock in sudden infant death: parallels between a neonatal rat model of sudden death and infants who died of sudden infant death syndrome
    Jane Blood-Siegfried
    Duke University Medical Center, Durham, North Carolina 27707, USA
    Innate Immun 14:145-52. 2008
  6. doi request reprint A rubric for improving the quality of online courses
    Jane E Blood-Siegfried
    Duke University, USA
    Int J Nurs Educ Scholarsh 5:Article 34. 2008
  7. pmc Is shock a key element in the pathology of sudden infant death syndrome (SIDS)?
    Jane Blood-Siegfried
    School of Nursing, Duke University, Durham, North Carolina 27710, USA
    Biol Res Nurs 11:187-94. 2009
  8. pmc The role of infection and inflammation in sudden infant death syndrome
    Jane Blood-Siegfried
    Duke University, School of Nursing, Box 3322, Durham, NC 27710, USA
    Immunopharmacol Immunotoxicol 31:516-23. 2009
  9. pmc The long-term effects of prenatal nicotine exposure on neurologic development
    Jane Blood-Siegfried
    Duke University, School of Nursing, Box 3322, Durham, NC 27710, USA
    J Midwifery Womens Health 55:143-52. 2010

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Sudden infant death syndrome: a toxic response
    J Blood-Siegfried
    Duke University, School of Nursing, PO Box 3322, Durham, NC 27710, USA
    AACN Clin Issues 11:300-8. 2000
    ..This article reviews the literature and possible causes of this devastating condition...
  2. ncbi request reprint Synergistic effect of influenza a virus on endotoxin-induced mortality in rat pups: a potential model for sudden infant death syndrome
    Jane Blood-Siegfried
    Environmental Immunology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Pediatr Res 52:481-90. 2002
    ..Our model suggests that the developing immune system can be primed to respond in an exaggerated way to a second immune challenge resulting in unexpected death...
  3. ncbi request reprint Animal models of sudden unexplained death
    Jane Blood-Siegfried
    School of Nursing, Duke University, Box 3322, Durham, NC 27707, USA
    FEMS Immunol Med Microbiol 42:34-41. 2004
    ..This review focuses on models developed to examine the association of infection and inflammation with mechanisms proposed to explain sudden unexplained death...
  4. ncbi request reprint Alteration in regulation of inflammatory response to influenza a virus and endotoxin in suckling rat pups: a potential relationship to sudden infant death syndrome
    Jane Blood-Siegfried
    Environmental Immunology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    FEMS Immunol Med Microbiol 42:85-93. 2004
    ..This results in an increased nitric oxide synthase production, most likely the cause of liver pathology and clotting abnormalities...
  5. pmc Evidence for infection, inflammation and shock in sudden infant death: parallels between a neonatal rat model of sudden death and infants who died of sudden infant death syndrome
    Jane Blood-Siegfried
    Duke University Medical Center, Durham, North Carolina 27707, USA
    Innate Immun 14:145-52. 2008
    ..The similarities between the neonatal rats and the human cases indicate that further research with the model might elucidate additional aspects of SIDS pathology...
  6. doi request reprint A rubric for improving the quality of online courses
    Jane E Blood-Siegfried
    Duke University, USA
    Int J Nurs Educ Scholarsh 5:Article 34. 2008
    ..The project had a positive impact on faculty by offering a tool useful for online course evaluation and development. Additionally it brought to attention the needs of faculty member development in online education...
  7. pmc Is shock a key element in the pathology of sudden infant death syndrome (SIDS)?
    Jane Blood-Siegfried
    School of Nursing, Duke University, Durham, North Carolina 27710, USA
    Biol Res Nurs 11:187-94. 2009
    ..This is exacerbated by perinatal nicotine exposure, a condition shown to alter the autonomic response in exposed offspring. We are proposing that shock and cardiovascular collapse is a key element that links these theories...
  8. pmc The role of infection and inflammation in sudden infant death syndrome
    Jane Blood-Siegfried
    Duke University, School of Nursing, Box 3322, Durham, NC 27710, USA
    Immunopharmacol Immunotoxicol 31:516-23. 2009
    ..Although the causal link between infection and SIDS is not conclusive, there is evidence that an infectious insult could be a likely trigger of SIDS in some infants...
  9. pmc The long-term effects of prenatal nicotine exposure on neurologic development
    Jane Blood-Siegfried
    Duke University, School of Nursing, Box 3322, Durham, NC 27710, USA
    J Midwifery Womens Health 55:143-52. 2010
    ..Understanding the effects of nicotine exposure is important in providing safe care for pregnant women, children, and families and for developing appropriate smoking cessation programs during pregnancy...

Research Grants3

  1. Effect of Perinatal Nicotine Exposure on the Development of Autonomic Responses
    Jane Blood Siegfried; Fiscal Year: 2009
    ..Aim 4: Examine specific actions of autonomic response by blocking sympathetic or parasympathetic pathways with pharmacologic agents. ..
  2. Effect of Perinatal Nicotine Exposure on the Development of Autonomic Responses
    JANE ELIZABETH BLOOD SIEGFRIED; Fiscal Year: 2010
    ..Aim 4: Examine specific actions of autonomic response by blocking sympathetic or parasympathetic pathways with pharmacologic agents. ..