John Beyer

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint An evidence-based medicine strategy for achieving remission in bipolar disorder
    John L Beyer
    Duke Mood and Anxiety Disorder Clinic, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Psychiatry 69:31-7. 2008
  2. ncbi request reprint Medical comorbidity in a bipolar outpatient clinical population
    John Beyer
    Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    Neuropsychopharmacology 30:401-4. 2005
  3. ncbi request reprint Hyperintense MRI lesions in bipolar disorder: A meta-analysis and review
    John L Beyer
    Department of Psychiatry, Duke University Medical Center, Durham, North Carolina, USA
    Int Rev Psychiatry 21:394-409. 2009
  4. ncbi request reprint Patterns of pharmacotherapy and treatment response in elderly adults with bipolar disorder
    John L Beyer
    Department of Psychiatry, Duke University Medical Center, Durham, NC, USA
    Psychopharmacol Bull 41:102-14. 2008
  5. ncbi request reprint Volumetric brain imaging findings in mood disorders
    John L Beyer
    Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    Bipolar Disord 4:89-104. 2002
  6. doi request reprint Gray and white matter brain volumes in older adults with bipolar disorder
    John L Beyer
    Duke University Medical Center, Department of Psychiatry and Behavioral Sciences, Neuropsychiatric Imaging Research Laboratory, USA
    Int J Geriatr Psychiatry 24:1445-52. 2009
  7. pmc Stressful life events in older bipolar patients
    John L Beyer
    Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    Int J Geriatr Psychiatry 23:1271-5. 2008
  8. ncbi request reprint Managing depression in geriatric populations
    John L Beyer
    Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    Ann Clin Psychiatry 19:221-38. 2007
  9. ncbi request reprint Prevalence of HIV infection in a general psychiatric outpatient population
    John L Beyer
    Duke University Medical Center, Department of Psychiatry, Durham, NC, USA
    Psychosomatics 48:31-7. 2007
  10. ncbi request reprint Volumetric brain imaging studies in the elderly with mood disorders
    John L Beyer
    Curr Psychiatry Rep 8:18-24. 2006

Research Grants

  1. BIPOLAR DISORDER IN LATE LIFE
    John Beyer; Fiscal Year: 2009
  2. Acute and Continuation Treatment in Late Life Mania
    John Beyer; Fiscal Year: 2007

Detail Information

Publications22

  1. ncbi request reprint An evidence-based medicine strategy for achieving remission in bipolar disorder
    John L Beyer
    Duke Mood and Anxiety Disorder Clinic, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Psychiatry 69:31-7. 2008
    ..The purpose of this article is to briefly summarize the clinical importance of remission in bipolar disorder and to review data on the effectiveness of available treatments for achieving and sustaining remission...
  2. ncbi request reprint Medical comorbidity in a bipolar outpatient clinical population
    John Beyer
    Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    Neuropsychopharmacology 30:401-4. 2005
    ..In conclusion, comorbid medical illnesses are common in bipolar outpatients, increasing with age. HIV rates may be increased relative to population norms. Their presence compounds the severity of the illness at time of presentation...
  3. ncbi request reprint Hyperintense MRI lesions in bipolar disorder: A meta-analysis and review
    John L Beyer
    Department of Psychiatry, Duke University Medical Center, Durham, North Carolina, USA
    Int Rev Psychiatry 21:394-409. 2009
    ..This study was conducted to use meta-analytic techniques to investigate the association of hyperintensities and bipolar illness and to evaluate the current state of the literature...
  4. ncbi request reprint Patterns of pharmacotherapy and treatment response in elderly adults with bipolar disorder
    John L Beyer
    Department of Psychiatry, Duke University Medical Center, Durham, NC, USA
    Psychopharmacol Bull 41:102-14. 2008
    ..This study assessed patterns of psychopharmacological treatment and treatment response in acutely ill, bipolar patients over the age of 60...
  5. ncbi request reprint Volumetric brain imaging findings in mood disorders
    John L Beyer
    Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    Bipolar Disord 4:89-104. 2002
    ..We review the findings for the various regions of the brain, and discuss the implications on the understanding of mood disorders. Directions for future research in volumetric imaging is then discussed...
  6. doi request reprint Gray and white matter brain volumes in older adults with bipolar disorder
    John L Beyer
    Duke University Medical Center, Department of Psychiatry and Behavioral Sciences, Neuropsychiatric Imaging Research Laboratory, USA
    Int J Geriatr Psychiatry 24:1445-52. 2009
    ..This study assessed the presence of gray matter volume, and the potential for regional volumetric differences in older adults with bipolar disorder...
  7. pmc Stressful life events in older bipolar patients
    John L Beyer
    Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    Int J Geriatr Psychiatry 23:1271-5. 2008
    ..Few studies have examined SLE in older bipolar patients. We wanted to assess the impact of SLE in late life bipolar disorder..
  8. ncbi request reprint Managing depression in geriatric populations
    John L Beyer
    Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    Ann Clin Psychiatry 19:221-38. 2007
    ..The last few years has witnessed an explosion in the research literature changing our understanding of this disease...
  9. ncbi request reprint Prevalence of HIV infection in a general psychiatric outpatient population
    John L Beyer
    Duke University Medical Center, Department of Psychiatry, Durham, NC, USA
    Psychosomatics 48:31-7. 2007
    ..The major psychiatric diagnostic categories with a high prevalence of HIV infection were substance abuse disorders (5%), personality disorders (3.1%), bipolar disorders (2.6%), and posttraumatic stress disorder (2.1%)...
  10. ncbi request reprint Volumetric brain imaging studies in the elderly with mood disorders
    John L Beyer
    Curr Psychiatry Rep 8:18-24. 2006
    ..This article reviews articles describing findings of volumetric analyses in elderly with unipolar depression and bipolar disorders, and compares and contrasts these findings with the larger volumetric research in affective disorders...
  11. ncbi request reprint Cortical white matter microstructural abnormalities in bipolar disorder
    John L Beyer
    Department of Psychiatry and Behavioral Science, Duke University Medical Center, Box 3519 DUMC, Durham, NC 27710, USA
    Neuropsychopharmacology 30:2225-9. 2005
    ..Further research is needed to better understand the interaction of microstructural changes and bipolar symptoms and whether these changes are specific to bipolar disorder...
  12. ncbi request reprint Hippocampal volume measurement in older adults with bipolar disorder
    John L Beyer
    Dept of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    Am J Geriatr Psychiatry 12:613-20. 2004
    ..Initial studies of mixed-aged bipolar subjects and controls have had conflicting findings, with most noting no difference; however this region has not been examined in older bipolar subjects...
  13. ncbi request reprint Social support in elderly patients with bipolar disorder
    John L Beyer
    Duke University Medical Center, Department of Psychiatry, Durham, NC 27710, USA
    Bipolar Disord 5:22-7. 2003
    ..Our purpose was to evaluate social support in older adults with bipolar disorder compared with peer controls and younger bipolar patients. In addition, we looked at the role of social support in the age of illness onset...
  14. ncbi request reprint Caudate volume measurement in older adults with bipolar disorder
    John L Beyer
    Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    Int J Geriatr Psychiatry 19:109-14. 2004
    ..No differences have been noted in initial studies of multi-aged bipolar subjects; however, this region has not been examined in older bipolar subjects...
  15. pmc The COMT Val158Met polymorphism and temporal lobe morphometry in healthy adults
    Warren D Taylor
    Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA
    Psychiatry Res 155:173-7. 2007
    ..5T brain MRI and genotyping. After controlling for demographics, Val158 allele homozygotes exhibited significantly smaller temporal lobe and hippocampal volumes, with a trend for smaller amygdala volumes...
  16. pmc Functional evidence implicating a novel TOR1A mutation in idiopathic, late-onset focal dystonia
    Nicole Calakos
    Center for Translational Neuroscience, Box 2900, Research Dr, Duke University Medical Center, Durham, NC 27710, USA
    J Med Genet 47:646-50. 2010
    ..Because of the established role of the TOR1A gene in heritable generalised dystonia (DYT1), a potential genetic contribution of TOR1A to the more prevalent and diverse presentations of late onset, focal dystonia has been suggested...
  17. pmc Temporal lobe volume in bipolar disorder: relationship with diagnosis and antipsychotic medication use
    Lindsay D Jones
    The Neuropsychiatric Imaging Research Laboratory, Duke University, Durham, North Carolina, United States
    J Affect Disord 114:50-7. 2009
    ..We tested for differences in temporal lobe volume in bipolar disorder and the relationship between these volumes and psychotropic medication use...
  18. pmc Age-dependent reduction of amygdala volume in bipolar disorder
    Tracy J Doty
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
    Psychiatry Res 163:84-94. 2008
    ..Differential aging effects in bipolar disorder may compromise amygdala integrity and contribute to mood dysregulation...
  19. ncbi request reprint Methodology and preliminary results from the neurocognitive outcomes of depression in the elderly study
    David C Steffens
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Geriatr Psychiatry Neurol 17:202-11. 2004
    ..These results are consistent with prior evidence linking depression and later dementia. Future studies are needed to examine neuroimaging and genetic, clinical, and social predictors of neurocognitive decline in depression...
  20. ncbi request reprint Treatment of older adults with co-morbid personality disorder and depression: a dialectical behavior therapy approach
    Thomas R Lynch
    Cognitive Behavioral Research and Treatment Program, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center Duke University, Box 3026, 2213 Elba Street, Durham, North Carolina 27710, USA
    Int J Geriatr Psychiatry 22:131-43. 2007
    ..It has also been demonstrated that personality disorders in older adults complicate treatment of other psychopathology, as well as result in heightened interpersonal disturbance and emotional distress...
  21. ncbi request reprint Pharmacotherapy of bipolar disorder in old age: review and recommendations
    Robert C Young
    Payne Whitney, Westchester, and the Institute for Geriatric Psychiatry, Department of Psychiatry, Weill Medical College of Cornell University, 21 Bloomingdale Road, White Plains, New York 10605, USA
    Am J Geriatr Psychiatry 12:342-57. 2004
    ..Similarly, there are no systematic studies of the treatment of BP depression in elderly patients. The authors make suggestions for management and delineate priorities for research...
  22. ncbi request reprint Medical comorbidity in bipolar disorder: re-prioritizing unmet needs
    Roger S McIntyre
    Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Curr Opin Psychiatry 20:406-16. 2007
    ..The aim of this review is to synthesize results from extant investigations which report on the co-occurrence of bipolar disorder and medical comorbidity...

Research Grants4

  1. BIPOLAR DISORDER IN LATE LIFE
    John Beyer; Fiscal Year: 2009
    ..This research is unique and is likely to enhance our understanding of the phenomenology, course, outcome and relationship of MRI changes to the pathophysiology of bipolar disorder in late life. ..
  2. Acute and Continuation Treatment in Late Life Mania
    John Beyer; Fiscal Year: 2007
    ..The sites have a history of successful collaborative research, including demanding geriatric studies. ..