Affiliation: Duke University Medical Center
- Cse1l is a negative regulator of CFTR-dependent fluid secretionMichel Bagnat
Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA
Curr Biol 20:1840-5. 2010..This work demonstrates the importance of fluid homeostasis in development and establishes the zebrafish as a much-needed model system to study CFTR regulation in vivo...
- Rapid identification of kidney cyst mutations by whole exome sequencing in zebrafishSean Ryan
Department of Cell Biology, Duke University, 333 B, Nanaline Duke Building, Durham, NC 27710, USA
Development 140:4445-51. 2013..This methodology should thus help facilitate genetic screens and expedite the identification of mutants that can inform basic biological processes and the causality of genetic disorders in humans. ..
- Cftr controls lumen expansion and function of Kupffer's vesicle in zebrafishAdam Navis
Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
Development 140:1703-12. 2013..These findings uncover a new role for cftr in KV morphogenesis and function during zebrafish development...