Vadim Arshavsky

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc Electrostatic and lipid anchor contributions to the interaction of transducin with membranes: mechanistic implications for activation and translocation
    Mickey Kosloff
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA
    J Biol Chem 283:31197-207. 2008
  2. pmc The outer segment serves as a default destination for the trafficking of membrane proteins in photoreceptors
    Sheila A Baker
    Albert Eye Research Institute, Duke University Medical Center, Durham, NC 27710, USA
    J Cell Biol 183:485-98. 2008
  3. pmc Integrating energy calculations with functional assays to decipher the specificity of G protein-RGS protein interactions
    Mickey Kosloff
    Duke Eye Center, Duke University Medical Center, Durham, North Carolina, USA
    Nat Struct Mol Biol 18:846-53. 2011
  4. pmc RGS9 knockout causes a short delay in light responses of ON-bipolar cells
    Rolf Herrmann
    Albert Eye Research Institute, Duke University, Durham, North Carolina, United States of America
    PLoS ONE 6:e27573. 2011
  5. pmc A single valine residue plays an essential role in peripherin/rds targeting to photoreceptor outer segments
    Raquel Y Salinas
    Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, United States of America
    PLoS ONE 8:e54292. 2013
  6. pmc Photoreceptor signaling: supporting vision across a wide range of light intensities
    Vadim Y Arshavsky
    Departments of Ophthalmology and Pharmacology, Duke University, Durham, North Carolina 27710, USA
    J Biol Chem 287:1620-6. 2012
  7. doi Vision: the retinoid cycle in Drosophila
    Vadim Y Arshavsky
    Duke University Eye Center, Durham, NC 27710, USA
    Curr Biol 20:R96-8. 2010

Research Grants

  1. Proteome Map of the Photoreceptor Cell
    Vadim Arshavsky; Fiscal Year: 2007

Collaborators

  • Mickey Kosloff
  • Emil Alexov
  • Sheila A Baker
  • Raquel Y Salinas
  • Rolf Herrmann
  • Sidney M Gospe
  • Bowa Lee
  • Mohammad Haeri
  • Barry E Knox
  • Peter Yoo
  • Nikolai P Skiba

Detail Information

Publications7

  1. pmc Electrostatic and lipid anchor contributions to the interaction of transducin with membranes: mechanistic implications for activation and translocation
    Mickey Kosloff
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA
    J Biol Chem 283:31197-207. 2008
    ..In a broader view, this work exemplifies how the activity-dependent association and dissociation of a G protein can change both the affinity for membranes and the range of allowed orientations, thereby modulating G protein function...
  2. pmc The outer segment serves as a default destination for the trafficking of membrane proteins in photoreceptors
    Sheila A Baker
    Albert Eye Research Institute, Duke University Medical Center, Durham, NC 27710, USA
    J Cell Biol 183:485-98. 2008
    ..This also implies that every protein residing outside the outer segment must have a means to avoid this "default" trafficking flow...
  3. pmc Integrating energy calculations with functional assays to decipher the specificity of G protein-RGS protein interactions
    Mickey Kosloff
    Duke Eye Center, Duke University Medical Center, Durham, North Carolina, USA
    Nat Struct Mol Biol 18:846-53. 2011
    ..Finally, we show that our approach can be extended to analyze interaction specificity across other large protein families...
  4. pmc RGS9 knockout causes a short delay in light responses of ON-bipolar cells
    Rolf Herrmann
    Albert Eye Research Institute, Duke University, Durham, North Carolina, United States of America
    PLoS ONE 6:e27573. 2011
    ..This result is inconsistent with a slowdown of response propagation in ON-bipolar cells caused by the R9AP knockout, further arguing against the postsynaptic nature of the delayed b-wave phenotype in RGS9 and R9AP knockout mice...
  5. pmc A single valine residue plays an essential role in peripherin/rds targeting to photoreceptor outer segments
    Raquel Y Salinas
    Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, United States of America
    PLoS ONE 8:e54292. 2013
    ..This valine is conserved in all species and its mutation is sufficient to completely abrogate the targeting of full-length peripherin in mouse rods...
  6. pmc Photoreceptor signaling: supporting vision across a wide range of light intensities
    Vadim Y Arshavsky
    Departments of Ophthalmology and Pharmacology, Duke University, Durham, North Carolina 27710, USA
    J Biol Chem 287:1620-6. 2012
    ....
  7. doi Vision: the retinoid cycle in Drosophila
    Vadim Y Arshavsky
    Duke University Eye Center, Durham, NC 27710, USA
    Curr Biol 20:R96-8. 2010
    ..New studies indicate that this pathway is present in Drosophila and is vital for maintaining both the amount of visual pigment and photoreceptor health in light-exposed flies...

Research Grants1

  1. Proteome Map of the Photoreceptor Cell
    Vadim Arshavsky; Fiscal Year: 2007
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