B D Alexander

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. doi request reprint In vitro characterization of nebulizer delivery of liposomal amphotericin B aerosols
    Barbara D Alexander
    Division of Infectious Diseases, Department of Medicine, Duke University, Durham, NC 27710, USA
    Pharm Dev Technol 16:577-82. 2011
  2. pmc Comparative evaluation of Etest and sensititre yeastone panels against the Clinical and Laboratory Standards Institute M27-A2 reference broth microdilution method for testing Candida susceptibility to seven antifungal agents
    Barbara D Alexander
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Clin Microbiol 45:698-706. 2007
  3. doi request reprint Nebulizer delivery of micafungin aerosols
    Barbara D Alexander
    Division of Infectious Diseases, Department of Medicine, Duke University, Durham, North Carolina 27710, USA
    Pharmacotherapy 31:52-7. 2011
  4. doi request reprint Fatal Apophysomyces elegans infection transmitted by deceased donor renal allografts
    B D Alexander
    Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Am J Transplant 10:2161-7. 2010
  5. ncbi request reprint Study of renal safety in amphotericin B lipid complex-treated patients
    Barbara D Alexander
    Division of Infectious Diseases and International Health, Duke University Medical Center, Durham, North Carolina 27710, USA
    Clin Infect Dis 40:S414-21. 2005
  6. pmc The (1,3){beta}-D-glucan test as an aid to early diagnosis of invasive fungal infections following lung transplantation
    Barbara D Alexander
    Division of Infectious Diseases and International Health, Department of Medicine, Clinical Microbiology Laboratory, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Clin Microbiol 48:4083-8. 2010
  7. ncbi request reprint Cost savings with implementation of PNA FISH testing for identification of Candida albicans in blood cultures
    Barbara D Alexander
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Box 3035, Durham, NC 27710, USA
    Diagn Microbiol Infect Dis 54:277-82. 2006
  8. doi request reprint Survival after lung transplantation of cystic fibrosis patients infected with Burkholderia cepacia complex
    B D Alexander
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University School of Medicine, Durham, NC, USA
    Am J Transplant 8:1025-30. 2008
  9. doi request reprint Posaconazole as salvage therapy in patients with invasive fungal infections after solid organ transplant
    Barbara D Alexander
    Division of Infectious Diseases and International Health, Box 3035, Duke University Medical Center, Durham, NC 27710, USA
    Transplantation 86:791-6. 2008
  10. ncbi request reprint Non-comparative evaluation of the safety of aerosolized amphotericin B lipid complex in patients undergoing allogeneic hematopoietic stem cell transplantation
    B D Alexander
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Transpl Infect Dis 8:13-20. 2006

Research Grants

Detail Information

Publications55

  1. doi request reprint In vitro characterization of nebulizer delivery of liposomal amphotericin B aerosols
    Barbara D Alexander
    Division of Infectious Diseases, Department of Medicine, Duke University, Durham, NC 27710, USA
    Pharm Dev Technol 16:577-82. 2011
    ..Additional research on pulmonary delivery and clinical tolerability is warranted...
  2. pmc Comparative evaluation of Etest and sensititre yeastone panels against the Clinical and Laboratory Standards Institute M27-A2 reference broth microdilution method for testing Candida susceptibility to seven antifungal agents
    Barbara D Alexander
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Clin Microbiol 45:698-706. 2007
    ..However, further evaluation of their performance for determining the MICs of azoles, particularly for C. glabrata, is warranted...
  3. doi request reprint Nebulizer delivery of micafungin aerosols
    Barbara D Alexander
    Division of Infectious Diseases, Department of Medicine, Duke University, Durham, North Carolina 27710, USA
    Pharmacotherapy 31:52-7. 2011
    ..To determine the optimal nebulization system for aerosolizing micafungin and to further assess the physiochemical properties of aerosolized micafungin...
  4. doi request reprint Fatal Apophysomyces elegans infection transmitted by deceased donor renal allografts
    B D Alexander
    Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Am J Transplant 10:2161-7. 2010
    ..Attention to aseptic technique during organ recovery and processing is re-emphasized...
  5. ncbi request reprint Study of renal safety in amphotericin B lipid complex-treated patients
    Barbara D Alexander
    Division of Infectious Diseases and International Health, Duke University Medical Center, Durham, North Carolina 27710, USA
    Clin Infect Dis 40:S414-21. 2005
    ..These data provide evidence that ABLC may be used safely to treat patients who are at increased risk for renal impairment...
  6. pmc The (1,3){beta}-D-glucan test as an aid to early diagnosis of invasive fungal infections following lung transplantation
    Barbara D Alexander
    Division of Infectious Diseases and International Health, Department of Medicine, Clinical Microbiology Laboratory, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Clin Microbiol 48:4083-8. 2010
    ..Although the NPV of the BG test is high, the low PPV limits its utility as a screening tool for early diagnosis of IFI...
  7. ncbi request reprint Cost savings with implementation of PNA FISH testing for identification of Candida albicans in blood cultures
    Barbara D Alexander
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Box 3035, Durham, NC 27710, USA
    Diagn Microbiol Infect Dis 54:277-82. 2006
    ..Incorporating the C. albicans PNA FISH test as part of the initial identification algorithm for yeasts recovered from blood can result in substantial savings for hospitals...
  8. doi request reprint Survival after lung transplantation of cystic fibrosis patients infected with Burkholderia cepacia complex
    B D Alexander
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University School of Medicine, Durham, NC, USA
    Am J Transplant 8:1025-30. 2008
    ..00005). Following LT, infection with Bcc species other than B. cenocepacia does not significantly impact 5-year survival whereas infection with B. cenocepacia pretransplant is associated with decreased survival...
  9. doi request reprint Posaconazole as salvage therapy in patients with invasive fungal infections after solid organ transplant
    Barbara D Alexander
    Division of Infectious Diseases and International Health, Box 3035, Duke University Medical Center, Durham, NC 27710, USA
    Transplantation 86:791-6. 2008
    ..In this post hoc analysis of a large, open-label, multicenter study, we evaluated efficacy and safety of posaconazole, a new extended-spectrum triazole, as salvage therapy for IFIs in SOT recipients...
  10. ncbi request reprint Non-comparative evaluation of the safety of aerosolized amphotericin B lipid complex in patients undergoing allogeneic hematopoietic stem cell transplantation
    B D Alexander
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Transpl Infect Dis 8:13-20. 2006
    ..With only 1 of 40 subjects developing IFI while receiving treatment, the combination of fluconazole and inhaled ABLC warrants further study as antifungal prophylaxis following allogeneic HSCT...
  11. ncbi request reprint Candida glabrata fungemia in transplant patients receiving voriconazole after fluconazole
    Barbara D Alexander
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Transplantation 80:868-71. 2005
    ..Clinicians must maintain a high index of suspicion for these infections in highly susceptible hosts despite voriconazole therapy, particularly when voriconazole use is preceded by prolonged fluconazole exposure...
  12. pmc Aspergillus fumigatus empyema, arthritis, and calcaneal osteomyelitis in a lung transplant patient successfully treated with posaconazole
    Barbara Alexander Lodge
    Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Clin Microbiol 42:1376-8. 2004
    ..Marked clinical improvement occurred within 6 weeks of initiation of posaconazole therapy; after 6 months, infection had resolved at all sites. The patient has had no recurrence of infection...
  13. ncbi request reprint Infectious complications of lung transplantation
    B D Alexander
    Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Transpl Infect Dis 3:128-37. 2001
    ..The epidemiology, prophylaxis, and treatment of infections following lung transplantation are critical areas for continued research...
  14. ncbi request reprint Prophylaxis of invasive mycoses in solid organ transplantation
    Barbara D Alexander
    Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham North Carolina 27701, USA
    Curr Opin Infect Dis 15:583-9. 2002
    ..This paper will review the latest data pertinent to the development of effective regimens aimed at preventing invasive mycoses in the solid organ transplantation population...
  15. ncbi request reprint Diagnosis of fungal infection: new technologies for the mycology laboratory
    B D Alexander
    Transplant Infectious Diseases Services, Clinical Mycology Laboratory, Duke University Medical Center, Durham, NC 27710, USA
    Transpl Infect Dis 4:32-7. 2002
    ..Well-planned studies to evaluate the performance characteristics as well as appropriate clinical and cost-effective application of these new tests are needed...
  16. ncbi request reprint Caspofungin for invasive candidiasis at a tertiary care medical center
    Aimee K Zaas
    Division of Infectious Diseases and International Health, Duke University Medical Center, Durham, NC 27710, USA
    Am J Med 119:993.e1-6. 2006
    ..We report a single-center experience with 104 consecutive courses of caspofungin for the treatment of invasive candidiasis to evaluate a real-world performance of this drug...
  17. ncbi request reprint Severity of Clostridium difficile-associated diarrhea in solid organ transplant patients
    Z F Gellad
    Department of Medicine, Division of Gastroenterology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Transpl Infect Dis 9:276-80. 2007
    ..Exposure to corticosteroids was significantly associated with an increased risk of relapse and may warrant a longer treatment course...
  18. pmc Validation of laboratory screening criteria for herpes simplex virus testing of cerebrospinal fluid
    Kimberly E Hanson
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Clin Microbiol 45:721-4. 2007
    ..Communication between the clinician and the laboratory is imperative for a successful screening program...
  19. pmc Comparison of the Digene Hybrid Capture System Cytomegalovirus (CMV) DNA (version 2.0), Roche CMV UL54 analyte-specific reagent, and QIAGEN RealArt CMV LightCycler PCR reagent tests using AcroMetrix OptiQuant CMV DNA quantification panels and specimens fr
    Kimberly E Hanson
    Duke University Medical Center, Durham, NC 27710, USA
    J Clin Microbiol 45:1972-3. 2007
    ..PCR assays showed better speed, sensitivity, and specificity...
  20. ncbi request reprint Prospective Aspergillus galactomannan antigen testing in pediatric hematopoietic stem cell transplant recipients
    William J Steinbach
    Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    Pediatr Infect Dis J 26:558-64. 2007
    ..There have been few studies with this assay in pediatric patients, but early reports suggest that there may be differences in the performance such that false-positive GM tests in pediatric patients are more common than in adult patients...
  21. pmc Fungal infections in transplant and oncology patients
    Anna K Person
    Division of Infectious Diseases, Department of Medicine, Duke University Health System, Duke University School of Medicine, Box 102359, Durham, NC 27710, USA
    Infect Dis Clin North Am 24:439-59. 2010
    ..This article highlights recent advances and important factors to consider when treating transplant and oncology patients with IFIs...
  22. ncbi request reprint Echinocandins: role in antifungal therapy, 2005
    Aimee K Zaas
    Duke University Medical Center, Division of Infectious Diseases and International Health, Box 3355, Durham, NC 27710, USA
    Expert Opin Pharmacother 6:1657-68. 2005
    ..The current challenge is to discover the optimal place for the echinocandins in the treatment of invasive fungal infections...
  23. pmc Breakthrough invasive candidiasis in patients on micafungin
    Christopher D Pfeiffer
    Division of Infectious Diseases, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Microbiol 48:2373-80. 2010
    ..parapsilosis requires further study...
  24. pmc Factors associated with mortality in transplant patients with invasive aspergillosis
    John W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, AL 35294 0006, USA
    Clin Infect Dis 50:1559-67. 2010
    ..The purpose of this study was to evaluate factors associated with mortality in transplant patients with IA...
  25. ncbi request reprint New developments in the diagnosis and treatment of infections in lung transplant recipients
    Aimee K Zaas
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Box 3355, Durham, NC 27710, USA
    Respir Care Clin N Am 10:531-47. 2004
    ..Multicenter trials will expand the scope of diagnosis and management of these infections. A team approach by transplant physicians and infectious diseases experts is critical to the success of managing these complex patients...
  26. ncbi request reprint Virulence associated with outbreak-related strains of Burkholderia cepacia complex among a cohort of patients with bacteremia
    Christopher W Woods
    Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Clin Infect Dis 38:1243-50. 2004
    ..5; 95% confidence interval, 1.20-25.02). B. cenocepacia is an emerging nosocomial pathogen. Certain strains are associated with an enhanced capacity for interpatient spread and poor outcome...
  27. ncbi request reprint Fungal infections in transplant and oncology patients
    Anna K Person
    Division of Infectious Diseases, Department of Medicine, Duke University Health System, Duke University School of Medicine, Box 102359, Durham, NC 27710, USA
    Hematol Oncol Clin North Am 25:193-213. 2011
    ..This article highlights recent advances and important factors to consider when treating transplant and oncology patients with IFIs...
  28. pmc Sepsis, multiple organ failure, and death due to Pandoraea pnomenusa infection after lung transplantation
    Martin E Stryjewski
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University School of Medicine, Durham, North Carolina 27710, USA
    J Clin Microbiol 41:2255-7. 2003
    ..Heretofore considered soil bacteria and colonizers that infect patients with chronic lung diseases, Pandoraea species can produce severe infections...
  29. ncbi request reprint Viral infections after renal transplantation
    S R Smith
    Divisions of Nephrology and Infectious Diseases, Duke University Medical Center, Durham, NC 27710, USA
    Am J Kidney Dis 37:659-76. 2001
    ..This review summarizes the natural history, diagnosis, prevention, and treatment of many common viral infections after renal transplantation...
  30. pmc Cryptococcus neoformans isolates from transplant recipients are not selected for resistance to calcineurin inhibitors by current immunosuppressive regimens
    Jill R Blankenship
    Department of Molecular Genetics and Microbiology, 322 CARL Building, Box 3546, Duke University Medical Center, Research Drive, Durham, NC 27710, USA
    J Clin Microbiol 43:464-7. 2005
    ....
  31. doi request reprint Evaluation of a digital microfluidic real-time PCR platform to detect DNA of Candida albicans in blood
    W A Schell
    Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Eur J Clin Microbiol Infect Dis 31:2237-45. 2012
    ..albicans DNA by conventional and microfluidic real-time PCR, respectively, for a combined sensitivity of 94%. The microfluidic platform offers a significant technical advance in the detection of microbial DNA in clinical specimens...
  32. ncbi request reprint Non-Aspergillus fungal pneumonia in transplant recipients
    Sylvia F Costa
    Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Clin Chest Med 26:675-90, vii. 2005
    ..Pneumonia, one aspect of a myriad of clinical manifestations caused by these fungal pathogens, is discussed in this article...
  33. ncbi request reprint Posaconazole
    Elizabeth S Dodds Ashley
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Drugs Today (Barc) 41:393-400. 2005
    ..Clinical success rates thus far have been promising, although the exact role of this agent in treating and preventing invasive fungal infections is yet to be determined...
  34. doi request reprint Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET)
    Peter G Pappas
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham Medical Center, Birmingham, Alabama 35294 0006, USA
    Clin Infect Dis 50:1101-11. 2010
    ..Invasive fungal infections (IFIs) are a major cause of morbidity and mortality among organ transplant recipients. Multicenter prospective surveillance data to determine disease burden and secular trends are lacking...
  35. ncbi request reprint Hospital management of tuberculosis in a region with a low incidence of tuberculosis and a high prevalence of nontuberculous mycobacteria
    B D Alexander
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Infect Control Hosp Epidemiol 22:715-7. 2001
    ..Clinicians' assessments were sensitive for TB but had poor predictive value. The acid-fast smear was a weak predictor of TB, owing to a high rate of isolation of NTM...
  36. ncbi request reprint Spontaneous dermal abscesses and ulcers as a result of Serratia marcescens
    N Deborah Friedman
    Division of Infectious Diseases, Duke University Medical Center, Durham, NC 27710, USA
    J Am Acad Dermatol 49:S193-4. 2003
    ..These skin ulcers and underlying dermal abscesses were found to be a result of S marcescens, with the presumed portal of entry being a toe-web infection...
  37. ncbi request reprint Neonatal Candida meningitis: significance of cerebrospinal fluid parameters and blood cultures
    M Cohen-Wolkowiez
    Department of Pediatrics, Duke University, Durham, NC 27705, USA
    J Perinatol 27:97-100. 2007
    ..The purpose of this study was to examine the frequency of normal cerebrospinal fluid (CSF) parameters in Candida meningitis and the proportion of candidemia associated with Candida meningitis...
  38. pmc Quantification of 1,3-beta-D-glucan levels in children: preliminary data for diagnostic use of the beta-glucan assay in a pediatric setting
    P Brian Smith
    Department of Pediatrics, Division of Pediatric Infectious Diseases, Duke University Medical Center, Durham, North Carolina 27710, USA
    Clin Vaccine Immunol 14:924-5. 2007
    ..We found higher 1,3-beta-D-glucan levels in children than those previously reported in adults...
  39. ncbi request reprint Mortality and neurodevelopmental outcome after Staphylococcus aureus bacteremia in infants
    Michael Cohen-Wolkowiez
    Department of Pediatrics, Duke University, Durham, NC, USA
    Pediatr Infect Dis J 26:1159-61. 2007
    ..Infants with methicillin-resistant S. aureus infection had a longer median duration of bacteremia (4.5 versus 1 day, P = 0.01), but no difference in length of hospital stay, mortality, or neurodevelopmental impairment...
  40. pmc Microfluidic platform versus conventional real-time polymerase chain reaction for the detection of Mycoplasma pneumoniae in respiratory specimens
    Elizabeth Wulff-Burchfield
    School of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Diagn Microbiol Infect Dis 67:22-9. 2010
    ..Three of 59 (5.0%) NPWs were positive, and agreement between the methods was 98%. The microfluidic platform was equally sensitive but 3 times faster and offers an inexpensive and convenient diagnostic test for microbial DNA...
  41. ncbi request reprint An immune reconstitution syndrome-like illness associated with Cryptococcus neoformans infection in organ transplant recipients
    Nina Singh
    University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Clin Infect Dis 40:1756-61. 2005
    ..We describe an immune reconstitution syndrome (IRS)-like entity in the course of evolution of Cryptococcus neoformans infection in organ transplant recipients...
  42. pmc Pulmonary cryptococcosis in solid organ transplant recipients: clinical relevance of serum cryptococcal antigen
    Nina Singh
    University of Pittsburgh, Pennsylvania, USA
    Clin Infect Dis 46:e12-8. 2008
    ..The role of serum cryptococcal antigen in the diagnosis and determinants of antigen positivity in solid organ transplant (SOT) recipients with pulmonary cryptococcosis has not been fully defined...
  43. pmc Calcineurin inhibitor agents interact synergistically with antifungal agents in vitro against Cryptococcus neoformans isolates: correlation with outcome in solid organ transplant recipients with cryptococcosis
    Dimitrios P Kontoyiannis
    M D Anderson Cancer Center, University of Texas, Houston, Texas 77030 3930, USA
    Antimicrob Agents Chemother 52:735-8. 2008
    ....
  44. pmc Multicenter evaluation of the Candida albicans/Candida glabrata peptide nucleic acid fluorescent in situ hybridization method for simultaneous dual-color identification of C. albicans and C. glabrata directly from blood culture bottles
    Janeen R Shepard
    AdvanDx, Inc, 10A Roessler Road, Woburn, MA 01801, USA
    J Clin Microbiol 46:50-5. 2008
    ..albicans and C. glabrata in positive blood culture bottles. This rapid assay may aid in the selection of initial antifungal drugs, leading to improved patient outcomes...
  45. ncbi request reprint Opportunistic mycelial fungal infections in organ transplant recipients: emerging importance of non-Aspergillus mycelial fungi
    Shahid Husain
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Clin Infect Dis 37:221-9. 2003
    ..Thus, non-Aspergillus molds have emerged as significant pathogens in organ transplant recipients. These molds are more likely to be associated with disseminated infections and to be associated with poorer outcomes than is aspergillosis...
  46. ncbi request reprint Risk factors for Burkholderia cepacia complex bacteremia among intensive care unit patients without cystic fibrosis: a case-control study
    Adam M Bressler
    Infectious Disease Specialists of Atlanta and Clinical Microbiology Laboratory, DeKalb Medical Center, Atlanta, GA, USA
    Infect Control Hosp Epidemiol 28:951-8. 2007
    ..The Burkholderia cepacia complex is associated with colonization or disease in patients with cystic fibrosis (CF). For patients without CF, this complex is poorly understood apart from its presence in occasional point source outbreaks...
  47. ncbi request reprint Infections due to Scedosporium apiospermum and Scedosporium prolificans in transplant recipients: clinical characteristics and impact of antifungal agent therapy on outcome
    Shahid Husain
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Clin Infect Dis 40:89-99. 2005
    ..Unique characteristics, impact of therapy with antifungal agents, and outcome of infections with Scedosporium species were assessed in transplant recipients...
  48. ncbi request reprint Cryptococcosis after solid organ transplantation
    Barbara D Alexander
    Transpl Infect Dis 7:1-3. 2005
  49. ncbi request reprint Multicenter clinical evaluation of the (1-->3) beta-D-glucan assay as an aid to diagnosis of fungal infections in humans
    Luis Ostrosky-Zeichner
    University of Texas Houston Medical School, Houston, TX 77030, USA
    Clin Infect Dis 41:654-9. 2005
    ..Measurement of (1-->3)-beta-D-Glucan (BG) has emerged as an adjunct diagnostic strategy for invasive fungal infections (IFI)...
  50. pmc Burkholderia glumae infection in an infant with chronic granulomatous disease
    Jason B Weinberg
    Division of Infectious Deseases, Department of Pediatrics and Communicable Deseases, University of Michigan Medical School, Ann Arbor, MI, USA
    J Clin Microbiol 45:662-5. 2007
    ..While other Burkholderia species have been identified as important pathogens in persons with CGD, B. glumae has not been previously reported to cause human infection...
  51. ncbi request reprint Allograft loss in renal transplant recipients with cryptococcus neoformans associated immune reconstitution syndrome
    Nina Singh
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Transplantation 80:1131-3. 2005
    ..0004). Temporal association of graft loss with IRS suggests a common pathophysiologic basis for these entities with implications relevant for the optimal management of renal transplant recipients with cryptococcosis...
  52. ncbi request reprint Clinical research in the lay press: irresponsible journalism raises a huge dose of doubt
    Elias J Anaissie
    Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Clin Infect Dis 43:1031-9. 2006
  53. ncbi request reprint Antifungal management practices and evolution of infection in organ transplant recipients with cryptococcus neoformans infection
    Nina Singh
    University of Pittsburgh Medical Center, Pittsburgh, PA 15240, USA
    Transplantation 80:1033-9. 2005
    ..The risk of relapse and time to recurrence is not known. We assessed antifungal treatment practices for cryptococcosis in a cohort of prospectively followed organ transplant recipients...
  54. pmc Cryptococcus neoformans in organ transplant recipients: impact of calcineurin-inhibitor agents on mortality
    Nina Singh
    University of Pittsburgh Medical Center, Pittsburgh, PA 15240, USA
    J Infect Dis 195:756-64. 2007
    ..Additionally, discerning the basis for transplant type-specific differences in disease severity has implications relevant for yielding further insights into the pathogenesis of C. neoformans infection in transplant recipients...
  55. pmc Central nervous system cryptococcosis in solid organ transplant recipients: clinical relevance of abnormal neuroimaging findings
    Nina Singh
    University of Pittsburgh, Pittsburgh, PA, USA
    Transplantation 86:647-51. 2008
    ..Prognostic implications of cryptococcal antigen and outcomes associated with central nervous system (CNS) cryptococcal lesions in solid organ transplant recipients have not been fully defined...

Research Grants3

  1. Prevention/diagnosis/fungal infections/transplantation
    Barbara Alexander; Fiscal Year: 2005
    ..This approach will shorten the time from development to clinical implementation in therapeutic trials and guidelines. ..
  2. Mid-Career Investigator Award: Preventing and Diagnosing Fungal Disease
    Barbara Alexander; Fiscal Year: 2007
    ....