Amy P Abernethy

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc Predictors of chronic breathlessness: a large population study
    Jacqueline A Bowden
    Cancer Council, South Australia, 202 Greenhill Rd, Parkside, South Australia, Australia
    BMC Public Health 11:33. 2011
  2. pmc Specialized palliative care services are associated with improved short- and long-term caregiver outcomes
    Amy P Abernethy
    Department of Palliative and Supportive Services, Flinders University, Bedford Park, South Australia 5042, Australia
    Support Care Cancer 16:585-97. 2008
  3. ncbi request reprint A health economic model of breakthrough pain
    Amy P Abernethy
    Center for Palliative Care, Duke University School of Medicine, DUMC 3436, Durham, NC 27710, USA
    Am J Manag Care 14:S129-40. 2008
  4. doi request reprint Delivery strategies to optimize resource utilization and performance status for patients with advanced life-limiting illness: results from the "palliative care trial" [ISRCTN 81117481]
    Amy P Abernethy
    Division of Medical Oncology, Duke University Medical Center, Durham, North Carolina, USA
    J Pain Symptom Manage 45:488-505. 2013
  5. pmc Phase 2 pilot study of Pathfinders: a psychosocial intervention for cancer patients
    Amy P Abernethy
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center DUMC, Durham, NC 27710, USA
    Support Care Cancer 18:893-8. 2010
  6. pmc Enhancing communication between oncologists and patients with a computer-based training program: a randomized trial
    James A Tulsky
    Duke University, Veterans Affairs Medical Center, Durham, North Carolina, USA
    Ann Intern Med 155:593-601. 2011
  7. pmc Do patient attributes predict oncologist empathic responses and patient perceptions of empathy?
    Kathryn I Pollak
    Duke Comprehensive Cancer Center, Cancer Prevention, Detection and Control Research Program, Duke University School of Medicine, Durham, USA
    Support Care Cancer 18:1405-11. 2010
  8. doi request reprint Variations in use of PET among Medicare beneficiaries with non-small cell lung cancer, 1998-2007
    Michaela A Dinan
    Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    Radiology 267:807-17. 2013
  9. pmc Correlates of quality of life-related outcomes in breast cancer patients participating in the Pathfinders pilot study
    SOPHIA K SMITH
    Duke Comprehensive Cancer Center, Duke University Medical Center DUMC, Durham, NC 27710, USA
    Psychooncology 20:559-64. 2011
  10. doi request reprint Validation of the Patient Care Monitor (Version 2.0): a review of system assessment instrument for cancer patients
    Amy P Abernethy
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Pain Symptom Manage 40:545-58. 2010

Detail Information

Publications132 found, 100 shown here

  1. pmc Predictors of chronic breathlessness: a large population study
    Jacqueline A Bowden
    Cancer Council, South Australia, 202 Greenhill Rd, Parkside, South Australia, Australia
    BMC Public Health 11:33. 2011
    ..This study aims to define these predictors of chronic breathlessness at a population level...
  2. pmc Specialized palliative care services are associated with improved short- and long-term caregiver outcomes
    Amy P Abernethy
    Department of Palliative and Supportive Services, Flinders University, Bedford Park, South Australia 5042, Australia
    Support Care Cancer 16:585-97. 2008
    ..The goal of this study was to evaluate, at a population level, the association between specialized palliative care services (SPCS) and short- and long-term caregiver outcomes...
  3. ncbi request reprint A health economic model of breakthrough pain
    Amy P Abernethy
    Center for Palliative Care, Duke University School of Medicine, DUMC 3436, Durham, NC 27710, USA
    Am J Manag Care 14:S129-40. 2008
    ..The paper then extends this model to the population level, providing a template for health economic analysis of alternate strategies for managing BTP, and delineating steps for accomplishing the analysis...
  4. doi request reprint Delivery strategies to optimize resource utilization and performance status for patients with advanced life-limiting illness: results from the "palliative care trial" [ISRCTN 81117481]
    Amy P Abernethy
    Division of Medical Oncology, Duke University Medical Center, Durham, North Carolina, USA
    J Pain Symptom Manage 45:488-505. 2013
    ..Evidence-based approaches are needed to improve the delivery of specialized palliative care...
  5. pmc Phase 2 pilot study of Pathfinders: a psychosocial intervention for cancer patients
    Amy P Abernethy
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center DUMC, Durham, NC 27710, USA
    Support Care Cancer 18:893-8. 2010
    ..This prospective, single-arm, phase 2 pilot study examined the acceptability and feasibility of Pathfinders for women with metastatic breast cancer...
  6. pmc Enhancing communication between oncologists and patients with a computer-based training program: a randomized trial
    James A Tulsky
    Duke University, Veterans Affairs Medical Center, Durham, North Carolina, USA
    Ann Intern Med 155:593-601. 2011
    ..Quality cancer care requires addressing patients' emotions, which oncologists infrequently do. Multiday courses can teach oncologists skills to handle emotion; however, such workshops are long and costly...
  7. pmc Do patient attributes predict oncologist empathic responses and patient perceptions of empathy?
    Kathryn I Pollak
    Duke Comprehensive Cancer Center, Cancer Prevention, Detection and Control Research Program, Duke University School of Medicine, Durham, USA
    Support Care Cancer 18:1405-11. 2010
    ..Oncologists may respond more empathically to some patients, and patients may perceive different levels of empathy and trust given past documentation of disparities in cancer care...
  8. doi request reprint Variations in use of PET among Medicare beneficiaries with non-small cell lung cancer, 1998-2007
    Michaela A Dinan
    Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    Radiology 267:807-17. 2013
    ..To explore demographic and regional factors associated with the use of positron emission tomography (PET) in patients with non-small cell lung cancer (NSCLC) and to determine whether their associations with PET use has changed over time...
  9. pmc Correlates of quality of life-related outcomes in breast cancer patients participating in the Pathfinders pilot study
    SOPHIA K SMITH
    Duke Comprehensive Cancer Center, Duke University Medical Center DUMC, Durham, NC 27710, USA
    Psychooncology 20:559-64. 2011
    ..This study explores the relationship between psychosocial resources invoked through the Pathfinders intervention and outcomes...
  10. doi request reprint Validation of the Patient Care Monitor (Version 2.0): a review of system assessment instrument for cancer patients
    Amy P Abernethy
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Pain Symptom Manage 40:545-58. 2010
    ..Although the PCM 1.0 is validated, the updated PCM 2.0 has not been validated nor tested in the academic setting...
  11. pmc Hazard-rate analysis and patterns of recurrence in early stage melanoma: moving towards a rationally designed surveillance strategy
    April K S Salama
    Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    PLoS ONE 8:e57665. 2013
    ..The objectives of this study were to identify patterns of metastatic recurrence, to determine the influence of metastatic site on survival, and to identify high-risk periods for recurrence...
  12. pmc Comparing oncologist, nurse, and physician assistant attitudes toward discussions of negative emotions with patients
    Perri A Morgan
    Duke University PA Program, Department of Community and Family Medicine, DUMC 104780, Durham, NC 27710, USA
    J Physician Assist Educ 21:13-7. 2010
    ..Nurses and physician assistants (PAs) may be able to help fill the need for empathic communication. Our study compares the attitudes of oncologists, nurses, and PAs toward communication with patients who demonstrate negative emotions...
  13. pmc Patient-oncologist communication in advanced cancer: predictors of patient perception of prognosis
    Tracy M Robinson
    Duke University School of Medicine, Durham, NC, USA
    Support Care Cancer 16:1049-57. 2008
    ..This study was designed to identify the communication factors that influence patient-oncologist concordance about chance of cure...
  14. doi request reprint What is the role of friends when contributing care at the end of life? Findings from an Australian population study
    Catherine M Burns
    Department of Palliative and Supportive Services, Flinders University, Bedford Park, South Australia, Australia
    Psychooncology 20:203-12. 2011
    ..To examine the role of friends as caregivers of people with terminal illness...
  15. ncbi request reprint Place of death for people with noncancer and cancer illness in South Australia: a population-based survey
    David C Currow
    Department of Palliative and Supportive Services, Flinders University, Bedford Park, South Australia
    J Palliat Care 24:144-50. 2008
    ..5%; p < 0.0001). Similar proportions had died in hospital (60%) and at home (16%-20%). Palliative care service involvement did not reduce institutional deaths, but shifted them from hospital to hospice...
  16. doi request reprint Assessment of the psychometric properties of an English version of the cancer dyspnea scale in people with advanced lung cancer
    Hope E Uronis
    Division of Medical Oncology, Duke University Medical Center, Durham, NC 27710, USA
    J Pain Symptom Manage 44:741-9. 2012
    ..Existing dyspnea measures fail to adequately address its multidimensionality. A Japanese group developed and validated the Cancer Dyspnea Scale (CDS) for assessing dyspnea in patients with advanced lung cancer...
  17. pmc Patient experiences with communication about sex during and after treatment for cancer
    Kathryn E Flynn
    Duke Clinical Research Institute, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC 27715, USA
    Psychooncology 21:594-601. 2012
    ..We studied patients' experiences with oncology providers regarding communication about sexual issues during and after treatment for cancer...
  18. pmc Dyspnea review for the palliative care professional: assessment, burdens, and etiologies
    Arif H Kamal
    Department of Medicine, Division of Medical Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Palliat Med 14:1167-72. 2011
    ..Its significance is amplified due to its impact on family and caregivers...
  19. pmc Caregivers for people with end-stage lung disease: characteristics and unmet needs in the whole population
    David C Currow
    Department of Palliative and Supportive Services, Flinders University, Adelaide, Australia
    Int J Chron Obstruct Pulmon Dis 3:753-62. 2008
    ..This paper describes demographic characteristics of caregivers, and key characteristics of the deceased irrespective of specialist service utilization...
  20. doi request reprint Development of a health information technology-based data system in community-based hospice and palliative care
    Amy P Abernethy
    Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Am J Prev Med 40:S217-24. 2011
    ..Few hospice and palliative care organizations use health information technology (HIT) for data collection and management; the feasibility and utility of a HIT-based approach in this multi-faceted, interdisciplinary context is unclear...
  21. doi request reprint Comfort in the last 2 weeks of life: relationship to accessing palliative care services
    David C Currow
    Department of Palliative and Supportive Services, Flinders University, Daw Park, Adelaide, South Australia
    Support Care Cancer 16:1255-63. 2008
    ..The aim of this study was to assess whether perceived comfort in the last 2 weeks of life was associated with accessing SPCS...
  22. pmc How do non-physician clinicians respond to advanced cancer patients' negative expressions of emotions?
    Stewart C Alexander
    Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Support Care Cancer 19:155-9. 2011
    ....
  23. pmc The longitudinal pattern of response when morphine is used to treat chronic refractory dyspnea
    David C Currow
    Palliative and Supportive Services, Flinders University, Bedford Park, Australia
    J Palliat Med 16:881-6. 2013
    ..The aim of this study is to describe this pattern...
  24. ncbi request reprint The clinical and social dimensions of prescribing palliative home oxygen for refractory dyspnea
    Katrina Breaden
    Palliative and Support Services, Flinders University, Adelaide, South Australia, Australia
    J Palliat Med 16:268-73. 2013
    ..The aim of this qualitative study was to understand the factors that most influence Australian specialist palliative care nurses' initiation of home oxygen for their patients...
  25. pmc Quality of life among long-term survivors of non-Hodgkin lymphoma: a follow-up study
    SOPHIA K SMITH
    Duke University, Durham, NC 27710, USA
    J Clin Oncol 31:272-9. 2013
    ..We examined change over time in QOL among long-term survivors of non-Hodgkin lymphoma and identified demographic, clinical, and psychosocial risk factors for poor outcomes...
  26. doi request reprint Designing and conducting randomized controlled trials in palliative care: A summary of discussions from the 2010 clinical research forum of the Australian Palliative Care Clinical Studies Collaborative
    Tania M Shelby-James
    Discipline, Palliative and Supportive Services, Flinders University, Australia
    Palliat Med 26:1042-7. 2012
    ..Key recommendations are reported, including guidance on design; methodologies; and strategies for maximizing recruitment and retention. These recommendations will help to inform future trial design and conduct in palliative care...
  27. ncbi request reprint Treatment-related toxicity and supportive care in metastatic colorectal cancer
    S Yousuf Zafar
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center, 2424 Erwin Road, Suite G05, Hock Plaza, DUMC Box 2732, Durham, NC 27710, USA
    J Support Oncol 8:15-20. 2010
    ..These data, obtained from a usual-practice setting, provide benchmarks to improve clinical practice...
  28. pmc Improving health care efficiency and quality using tablet personal computers to collect research-quality, patient-reported data
    Amy P Abernethy
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Box 3436, Durham, NC 27710, USA
    Health Serv Res 43:1975-91. 2008
    ..DATA/SETTING: Primary/Duke Breast Cancer Clinic...
  29. doi request reprint Evaluation of 39 cases of pediatric cutaneous head and neck melanoma
    Win J Tcheung
    Duke University Medical Center, Department of Dermatology, Durham, North Carolina 27710, USA
    J Am Acad Dermatol 65:e37-42. 2011
    ..Studies examining head and neck (H&N) melanoma in the pediatric population are scarce...
  30. pmc Conformance with supportive care quality measures is associated with better quality of life in patients with cancer receiving palliative care
    Arif H Kamal
    Duke Cancer Institute, Duke University Medical Center, Durham, NC 27710, USA
    J Oncol Pract 9:e73-6. 2013
    ..As palliative care further integrates into cancer care, descriptions of how supportive care quality measures improve patient outcomes are necessary to establish best practices...
  31. pmc Overcoming recruitment challenges in palliative care clinical trials
    Thomas W Leblanc
    Duke University Medical Center Duke Cancer Institute Center for Learning Health Care, Duke Clinical Research Institute, Duke University, Durham, NC and Flinders University, Adelaide, Australia
    J Oncol Pract 9:277-82. 2013
    ..Major barriers include (1) patient factors, (2) "gatekeeping," and (3) ethical concerns. Here we discuss an approach to overcoming these barriers, using the Palliative Care Trial (PCT) as a case study...
  32. doi request reprint Off-label prescribing in palliative care - a cross-sectional national survey of palliative medicine doctors
    Timothy H M To
    Discipline, Palliative and Supportive Services, Flinders University, Adelaide, Australia
    Palliat Med 27:320-8. 2013
    ..Once registered, prescription is at clinicians' discretion. Off-label use is beyond the registered use. While off-label prescribing may, at times, be appropriate, efficacy and toxicity data are often lacking...
  33. doi request reprint Key characteristics of palliative care studies reported in the specialized literature
    Jane L Wheeler
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Pain Symptom Manage 43:987-92. 2012
    ..Although research activity in palliative care is rapidly increasing, the composition of published studies--in terms of significant research characteristics--has not yet been well described...
  34. doi request reprint Refining a checklist for reporting patient populations and service characteristics in hospice and palliative care research
    David C Currow
    Palliative and Supportive Services, Flinders University, Adelaide, South Australia, Australia
    J Pain Symptom Manage 43:902-10. 2012
    ..These three levels of variation limit the ability to generalize study findings...
  35. ncbi request reprint The impact of conducting a regional palliative care clinical study
    David C Currow
    Department of Palliative and Supportive Services, Flinders University, Bedford Park
    Palliat Med 20:735-43. 2006
    ..This study challenged and developed the research culture within our clinical team and subsequently translated into further research...
  36. doi request reprint Management of dyspnea in patients with chronic obstructive pulmonary disease
    Amy P Abernethy
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center DUMC, Durham, North Carolina 27710, USA
    Wien Med Wochenschr 159:583-90. 2009
    ..Topics include oxygen, opioids, psychotropic drugs, inhaled frusemide, Heliox28, nutrition, psychosocial support, and breathing techniques...
  37. doi request reprint The value of data collection within a palliative care program
    Arif H Kamal
    Duke Cancer Care Research Program, Duke Cancer Institute, Durham, NC, USA
    Curr Oncol Rep 13:308-15. 2011
    ..Suggested steps in forming data-sharing collaborations and building data collection procedures are shared...
  38. ncbi request reprint Creating a research culture in a palliative care service environment: a qualitative study of the evolution of staff attitudes to research during a large longitudinal controlled trial (ISRCTN81117481)
    Carol Grbich
    Department of Palliative and Supportive Services, Division of Medicine, Flinders University, Bedford Park, South Australia, Australia
    J Palliat Care 24:100-9. 2008
    ....
  39. doi request reprint Electronic patient-reported data capture as a foundation of rapid learning cancer care
    Amy P Abernethy
    Division of Medical Oncology, Department of Medicine, Duke University Health System, Duke University Medical Center DUMC, Durham, NC 27710, USA
    Med Care 48:S32-8. 2010
    ....
  40. ncbi request reprint Redistribution of health care costs after the adoption of positron emission tomography among medicare beneficiaries with non-small-cell lung cancer, 1998-2005
    Michaela A Dinan
    Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina Department of Health Policy and Administration, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina Department of Medicine, Duke University School of Medicine, Durham, North Carolina Duke Cancer Institute, Duke University School of Medicine, Durham, North Carolina and Department of Radiology, Duke University School of Medicine, Durham, North Carolina
    J Thorac Oncol 9:512-8. 2014
    ..We examined rates of surgery, radiotherapy, and chemotherapy and inpatient and total health care costs between 1998 and 2005 among Medicare beneficiaries with non-small-cell lung cancer...
  41. ncbi request reprint Targeted investment improves access to hospice and palliative care
    Amy P Abernethy
    Division of Medical Oncology, Duke University Medical Center, Durham, North Carolina, USA Department of Medicine, Duke Cancer Institute, Duke University Medical Center, Durham, North Carolina, USA Electronic address
    J Pain Symptom Manage 46:629-39. 2013
    ..Availability of hospice and palliative care is increasing, despite lack of a clear national strategy for developing and evaluating their penetration into and impact on the target population...
  42. doi request reprint Community-based palliative care: the natural evolution for palliative care delivery in the U.S
    Arif H Kamal
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    J Pain Symptom Manage 46:254-64. 2013
    ....
  43. ncbi request reprint Unmet spiritual care needs impact emotional and spiritual well-being in advanced cancer patients
    Michelle J Pearce
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
    Support Care Cancer 20:2269-76. 2012
    ..Do oncology inpatients receive spiritual care consistent with their needs? When inconsistent, are there deleterious effects on patient outcomes?..
  44. doi request reprint Clinicopathologic study of 85 cases of melanoma of the female genitalia
    Win J Tcheung
    Department of Dermatology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Acad Dermatol 67:598-605. 2012
    ..Melanoma of the female genitalia has poor overall prognosis...
  45. doi request reprint Stage migration, selection bias, and survival associated with the adoption of positron emission tomography among medicare beneficiaries with non-small-cell lung cancer, 1998-2003
    Michaela A Dinan
    Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    J Clin Oncol 30:2725-30. 2012
    ..However, this association may be confounded by PET-induced stage migration and selection bias. We examined the association between PET use and overall survival among Medicare beneficiaries with NSCLC...
  46. doi request reprint Improving the management of dyspnea in the community using rapid learning approaches
    Arif H Kamal
    Division of Medical Oncology, Department of Medicine, Duke Cancer Care Research Program, Duke Cancer Institute, Duke University Medical Center, NC 27710, USA
    Chron Respir Dis 9:51-61. 2012
    ..Using the rapid learning health care model, data collected in the process of routine care can simultaneously function both as clinical information and as a resource for research on patient-centered experiences and outcomes...
  47. pmc Caregivers' perceived adequacy of support in end-stage lung disease: results of a population survey
    David C Currow
    Discipline, Palliative and Supportive Services, Flinders University, Adelaide, Australia
    BMC Pulm Med 11:55. 2011
    ..End-stage lung disease (ESLD) is a frequent cause of death. What are the differences in the supports needed by caregivers of individuals with ESLD at end of life versus other life-limiting diagnoses?..
  48. doi request reprint Collecting data on quality is feasible in community-based palliative care
    Arif H Kamal
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Pain Symptom Manage 42:663-7. 2011
    ..We developed and tested the feasibility of the Quality Data Collection Tool version 1.0 (QDACTv1.0) for use in community-based palliative care...
  49. doi request reprint Do the trajectories of dyspnea differ in prevalence and intensity by diagnosis at the end of life? A consecutive cohort study
    David C Currow
    Department of Palliative and Supportive Services, Flinders University, Bedford Park, South Australia, Australia
    J Pain Symptom Manage 39:680-90. 2010
    ..Breathlessness reportedly worsens as death approaches for many people, but the differences in intensity and time course between underlying causes are not well described...
  50. ncbi request reprint Can we predict which patients with refractory dyspnea will respond to opioids?
    David C Currow
    Department of Palliative and Supportive Services, Division of Medicine, South Australia, Australia
    J Palliat Med 10:1031-6. 2007
    ..Dyspnea is frequently encountered in end-stage diseases even when reversible issues are addressed. Which clinical factors best define patient subpopulations that will most predictably benefit from opioids in this clinical setting?..
  51. doi request reprint Changes in the use and costs of diagnostic imaging among Medicare beneficiaries with cancer, 1999-2006
    Michaela A Dinan
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    JAMA 303:1625-31. 2010
    ..Imaging is the fastest growing expense for Medicare but has not been examined among beneficiaries with cancer...
  52. pmc The financial toxicity of cancer treatment: a pilot study assessing out-of-pocket expenses and the insured cancer patient's experience
    S Yousuf Zafar
    Center for Learning Health Care, Duke Clinical Research Institute, Duke Cancer Institute, Durham, North Carolina 27710, USA
    Oncologist 18:381-90. 2013
    ..Our objective was to describe experiences of insured cancer patients requesting copayment assistance and to describe the impact of health care expenses on well-being and treatment...
  53. doi request reprint Integrating technology into palliative care research
    Arif H Kamal
    Division of Medical Oncology, Duke Cancer Institute, Duke University Medical Center, Durham, North Carolina 27710, USA
    Curr Opin Support Palliat Care 6:525-32. 2012
    ..Reviewing reported successes of technology use in palliative care research is important to communicate lessons learned and principles to guide further implementation...
  54. doi request reprint The effect of metastatic site and decade of diagnosis on the individual burden of metastatic melanoma: contemporary estimates of average years of life lost
    April K S Salama
    Duke Comprehensive Cancer Center, Duke University Medical Center DUMC, Durham, North Carolina 27710, USA
    Cancer Invest 30:637-41. 2012
    ..Metastatic melanoma (MM) is a leading cause of years of life lost due to malignancy. This study aimed to identify the average years of life lost (AYLL) in MM patients...
  55. doi request reprint An international initiative to create a collaborative for pharmacovigilance in hospice and palliative care clinical practice
    David C Currow
    Discipline of Palliative and Supportive Services, Flinders University, Daw Park, South Australia, Australia
    J Palliat Med 15:282-6. 2012
    ..There is a need for prospective, systematic pharmacovigilance in hospice and palliative care...
  56. pmc Dyspnea review for the palliative care professional: treatment goals and therapeutic options
    Arif H Kamal
    Department of Medicine, Division of Medical Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Palliat Med 15:106-14. 2012
    ....
  57. doi request reprint Consensus-based standards for best supportive care in clinical trials in advanced cancer
    S Yousuf Zafar
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Lancet Oncol 13:e77-82. 2012
    ..Availability of resources was cited as a challenge to implementation of best supportive care standards...
  58. doi request reprint Utility and use of palliative care screening tools in routine oncology practice
    Amy P Abernethy
    Division of Medical Oncology, Department of Medicine, Duke Cancer Care Research Program, Duke Comprehensive Cancer Center, Duke University Medical Center, Durham, NC, USA
    Cancer J 16:444-60. 2010
    ....
  59. pmc Management of gastrointestinal symptoms in advanced cancer patients: the rapid learning cancer clinic model
    Amy P Abernethy
    Department of Medicine, Division of Medical Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Curr Opin Support Palliat Care 4:36-45. 2010
    ....
  60. pmc Effect of palliative oxygen versus room air in relief of breathlessness in patients with refractory dyspnoea: a double-blind, randomised controlled trial
    Amy P Abernethy
    Department of Medicine, Division of Medical Oncology, Duke University Medical Center, Durham, NC, USA
    Lancet 376:784-93. 2010
    ..We assessed the effectiveness of oxygen compared with room air delivered by nasal cannula for relief of breathlessness in this population of patients...
  61. doi request reprint Adverse events in hospice and palliative care: a pilot study to determine feasibility of collection and baseline rates
    David C Currow
    Discipline, Palliative and Supportive Services, Flinders University, Daw Park, South Australia, Australia
    J Palliat Med 14:309-14. 2011
    ..Identifying and systematically reducing symptomatic adverse events is limited in hospice and palliative care because these events are mostly attributed to disease progression...
  62. pmc Sexual concerns in cancer patients: a comparison of GI and breast cancer patients
    Jennifer Barsky Reese
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center DUMC, Durham, NC 27705, USA
    Support Care Cancer 18:1179-89. 2010
    ....
  63. pmc Palliative management of refractory dyspnea in COPD
    Hope E Uronis
    Department of Medicine, Division of Medical Oncology, Duke University Medical Center, Durham, NC 27710, USA
    Int J Chron Obstruct Pulmon Dis 1:289-304. 2006
    ..Topics include oxygen, opioids, psychotropic drugs, inhaled furosemide, Heliox, rehabilitation, nutrition, psychosocial support, breathing techniques, and breathlessness clinics...
  64. doi request reprint Decision making and quality of life in the treatment of cancer: a review
    S Yousuf Zafar
    Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Support Care Cancer 17:117-27. 2009
    ..Although these factors are important, physicians are often unable to effectively judge their patients' preferences. Patients are often unable to fully understand their prognoses and the treatment intent...
  65. doi request reprint Oxygen for relief of dyspnea: what is the evidence?
    Hope E Uronis
    Department of Medicine, Division of Medical Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Curr Opin Support Palliat Care 2:89-94. 2008
    ..e., when PaO2 is >/=55 mmHg; also known as palliative oxygen)...
  66. doi request reprint Advances in the pharmacological management of breathlessness
    David C Currow
    Flinders University, Daw Park, SA, Australia
    Curr Opin Support Palliat Care 3:103-6. 2009
    ..To explore advances in the pharmacological treatment of refractory breathlessness and the physiological evidence for treatments...
  67. doi request reprint Populations who die without specialist palliative care: does lower uptake equate with unmet need?
    David C Currow
    Department of Palliative and Supportive Services, Flinders University, Bedford Park, South Australia, Australia
    Palliat Med 22:43-50. 2008
    ..Have caregivers of patients who have not accessed SPCS had their needs met?..
  68. pmc Achieving palliative care research efficiency through defining and benchmarking performance metrics
    Jordan E Lodato
    Duke Center for Learning Healthcare, Duke Clinical Research Institute, Durham, North Carolina 27710, USA
    Curr Opin Support Palliat Care 6:533-42. 2012
    ..The Palliative Care Research Cooperative Group (PCRC) provides useful examples for ensuring research efficiency in palliative care...
  69. pmc Considerations in reporting palliative care clinical trials: standardizing information reported and authorship practices
    Thomas W Leblanc
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Curr Opin Support Palliat Care 6:494-9. 2012
    ..Here we discuss two core aspects of clinical trials reporting in palliative medicine: proposed standards governing the collection and reporting of data, and rules governing authorship and publication...
  70. doi request reprint Gastrointestinal symptoms in cancer patients with advanced disease: new methodologies, insights, and a proposed approach
    Fatima Rangwala
    Division of Medical Oncology, Department of Medicine, Duke University Medical Centre, Durham, North Carolina, USA
    Curr Opin Support Palliat Care 6:69-76. 2012
    ..This review summarizes recent developments in the management of gastrointestinal symptoms experienced by cancer patients and provides a framework for education, assessment and monitoring, and treatment...
  71. doi request reprint A multicenter prospective evaluation of the clinical utility of F-18 FDG-PET/CT in patients with AJCC stage IIIB or IIIC extremity melanoma
    Georgia M Beasley
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Ann Surg 256:350-6. 2012
    ....
  72. doi request reprint Standards for palliative care delivery in oncology settings
    S Yousuf Zafar
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, NC 27701, USA
    Cancer J 16:436-43. 2010
    ..Guideline efficacy has not been evaluated, and their dissemination into standard care has been poor. A conceptual framework for better implementation of existing guidelines might improve usage and outcomes...
  73. doi request reprint Association between the Medicare Modernization Act of 2003 and patient wait times and travel distance for chemotherapy
    Alisa M Shea
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    JAMA 300:189-96. 2008
    ..Anecdotal reports suggest that these adjustments may have negatively affected access to chemotherapy for Medicare beneficiaries...
  74. doi request reprint Management of dyspnea within a rapid learning healthcare model
    Amy P Abernethy
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Curr Opin Support Palliat Care 5:101-10. 2011
    ..This review places dyspnea management in palliative care within the new systems approach offered by rapid learning healthcare...
  75. doi request reprint Former palliative caregivers who identify that additional spiritual support would have been helpful in a population survey
    Meg M Hegarty
    Palliative and Supportive Services, Flinders University, Adelaide, Australia
    Palliat Med 25:266-77. 2011
    ..Palliative care encompasses physical, psychosocial and spiritual care for patients and caregivers. No population data are available on bereaved people who subsequently report that additional spiritual support would have been helpful...
  76. doi request reprint Breast cancer as heterogeneous disease: contributing factors and carcinogenesis mechanisms
    Julia Kravchenko
    Duke Cancer Institute, Duke University Medical Center, 2424 Erwin Road, Box 2732, Hock Plaza, Suite G05, Durham, NC 27705, USA
    Breast Cancer Res Treat 128:483-93. 2011
    ..The results of this study could suggest stratification rather than unification of breast cancer prevention strategies, risk assessment, and treatment...
  77. doi request reprint Total dyspnoea
    Amy P Abernethy
    Department of Medicine, Division of Medical Oncology, Duke University Medical Centre, Durham, North Carolina 27710, USA
    Curr Opin Support Palliat Care 2:110-3. 2008
    ....
  78. doi request reprint Do terminally ill people who live alone miss out on home oxygen treatment? An hypothesis generating study
    David C Currow
    Department of Palliative and Supportive Services, Flinders University, Bedford Park, South Australia, Australia
    J Palliat Med 11:1015-22. 2008
    ..Oxygen for refractory dyspnea at the end of life is commonly prescribed, even when the criteria for long-term home oxygen therapy are not met. Is palliative oxygen less likely to be prescribed when a person lives alone at the end of life?..
  79. ncbi request reprint A clinical decision and economic analysis model of cancer pain management
    Amy P Abernethy
    Center for Clinical Health Policy Research, Department of Medicine, Duke University Medical Center, 2200 W Main St, Suite 230, Durham, NC 27705, USA
    Am J Manag Care 9:651-64. 2003
    ....
  80. doi request reprint Palliative caregivers who would not take on the caring role again
    David C Currow
    Discipline of Palliative and Supportive Services, School of Medicine, Flinders University, Bedford Park, South Australia, Australia
    J Pain Symptom Manage 41:661-72. 2011
    ..Health and social services rely heavily on family and friends for caregiving at the end of life...
  81. doi request reprint International perspective: outcomes of palliative oncology
    David C Currow
    Flinders University Discipline, Palliative and Supportive Services, Bedford Park, South Australia, Australia
    Semin Oncol 38:343-50. 2011
    ..We make the case for international prioritization of palliative care as a critical strategy for improving outcomes for people with cancer and their caregivers worldwide...
  82. ncbi request reprint Prescribing in palliative care as death approaches
    David C Currow
    Department of Palliative and Supportive Services, Flinders University, Bedford Park, South Australia, Australia
    J Am Geriatr Soc 55:590-5. 2007
    ..To determine how prescribing for comorbid illnesses and symptom control changes during the palliative phase of a terminal illness...
  83. ncbi request reprint Psychological interventions for arthritis pain management in adults: a meta-analysis
    Kim E Dixon
    Department of Psychiatry and Behavioral Sciences, Pain Prevention and Treatment Research Program, Duke University Medical Center, Durham, NC 27710, USA
    Health Psychol 26:241-50. 2007
    ..The psychosocial impact of arthritis can be profound. There is growing interest in psychosocial interventions for managing pain and disability in arthritis patients...
  84. doi request reprint Palliative care pharmacotherapy literature summaries and analyses
    Amy P Abernethy
    Duke University Medical Center, Box 3436, Durham, NC 27710, USA
    J Pain Palliat Care Pharmacother 23:174-81. 2009
    ....
  85. ncbi request reprint A pragmatic 2 x 2 x 2 factorial cluster randomized controlled trial of educational outreach visiting and case conferencing in palliative care-methodology of the Palliative Care Trial [ISRCTN 81117481]
    Amy P Abernethy
    Department of Palliative and Supportive Services, Flinders University, Adelaide, South Australia, Australia
    Contemp Clin Trials 27:83-100. 2006
    ..Initial results are expected in mid 2005...
  86. ncbi request reprint Psychological approaches to understanding and treating disease-related pain
    Francis J Keefe
    Duke University Medical Center, Department of Psychiatry, Durham, NC 27705, USA
    Annu Rev Psychol 56:601-30. 2005
    ..In the final section, we describe important future directions, including strategies for disseminating psychosocial treatments and disparities in pain management...
  87. ncbi request reprint Specialist palliative care needs of whole populations: a feasibility study using a novel approach
    David C Currow
    Department of Palliative and Supportive Services, Division of Medicine, Flinders University, Adelaide and Southern Adelaide Palliative Services, Repatriation General Hospital, Daw Park, South Australia, Australia
    Palliat Med 18:239-47. 2004
    ..This study seeks to establish the viability of a whole-of-population method to help characterize SPCS access through proxy report...
  88. doi request reprint Once-daily opioids for chronic dyspnea: a dose increment and pharmacovigilance study
    David C Currow
    Discipline, Palliative and Supportive Services, Flinders University, Bedford Park, SA, Australia
    J Pain Symptom Manage 42:388-99. 2011
    ..Randomized controlled trials can answer questions of efficacy, but long-term pharmacovigilance studies generate complementary safety data...
  89. pmc A strategy to advance the evidence base in palliative medicine: formation of a palliative care research cooperative group
    Amy P Abernethy
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Palliat Med 13:1407-13. 2010
    ....
  90. ncbi request reprint Pain and palliative care pharmacotherapy literature summaries and analyses
    Amy P Abernethy
    Duke University Medical Center, Box 3436, Durham, NC27710, USA
    J Pain Palliat Care Pharmacother 22:145-51. 2008
    ....
  91. ncbi request reprint A community population survey of prevalence and severity of dyspnea in adults
    David C Currow
    Department of Palliative and Supportive Services, Flinders University, Adelaide, Australia
    J Pain Symptom Manage 38:533-45. 2009
    ..Given the prevalence, it is feasible to explore the onset of breathlessness, the underlying etiologies and subsequent health service utilization, and health consequences...
  92. pmc Comorbidity, age, race and stage at diagnosis in colorectal cancer: a retrospective, parallel analysis of two health systems
    S Yousuf Zafar
    Department of Medicine, Duke University Medical Center, Durham, USA
    BMC Cancer 8:345. 2008
    ..The objective of this study is to investigate how comorbidity, race and age influence stage of CRC diagnosis...
  93. pmc Rapid-learning system for cancer care
    Amy P Abernethy
    Duke Comprehensive Cancer Center, Duke University Medical Center, Box 3436, Durham, NC 27710, USA
    J Clin Oncol 28:4268-74. 2010
    ..This Special Article reviews the activities of the workshop and sets the stage to move from vision to action...
  94. doi request reprint Research in end-of-life settings: an ethical inquiry
    Thomas W Leblanc
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Pain Palliat Care Pharmacother 24:244-50. 2010
    ....
  95. doi request reprint Pharmacological management of dyspnoea
    David C Currow
    Department of Palliative and Supportive Services, Division of Medicine, Flinders University, Bedford Park, South Australia
    Curr Opin Support Palliat Care 1:96-101. 2007
    ..This paper reviews the current evidence for the pharmacological treatment of refractory symptomatic breathlessness in people with advanced life-limiting illnesses. The paper does not explore changes in function...
  96. doi request reprint A framework for generalizability in palliative care
    David C Currow
    Department of Palliative and Supportive Services, Flinders University, Adelaide, Australia
    J Pain Symptom Manage 37:373-86. 2009
    ..The framework has five domains: patients and caregivers; health professionals; service issues; health and social policy; and research...
  97. ncbi request reprint Use of tablet personal computers for sensitive patient-reported information
    Alexandra Dupont
    Department of Medicine, Division of Medical Oncology, Duke University Medical Center, Durham, North Carolina, USA
    J Support Oncol 7:91-7. 2009
    ..The e/Tablet electronic system may provide a "safer" environment than paper questionnaires for cancer patients to answer private or highly personal questions on sensitive topics such as sexuality...
  98. ncbi request reprint Small cell lung cancer presenting as a paraneoplastic syndrome characterized by recurrent episodic hypotension and bradycardia: case report
    Mike G Martin
    Department of Internal Medicine, Duke University Medical Center, Durham, NC, USA
    Chest 131:290-3. 2007
    ..Possible explanations included the following: intermittent great vessel obstruction; baroreceptor failure/hypersensitivity; and autonomic dysfunction. His clinical course favored an antibody-negative dysautonomic paraneoplastic syndrome...
  99. ncbi request reprint Studying communication in oncologist-patient encounters: the SCOPE Trial
    Celine M Koropchak
    Department of Medicine and Center for Palliative Care, Duke University Medical Center, Durham, NC 27705, USA
    Palliat Med 20:813-9. 2006
    ..In this report, we describe the study methods and identify challenges to implementation and how these were overcome...
  100. doi request reprint Pain and palliative care pharmacotherapy literature summaries and analyses
    Amy P Abernethy
    Duke Cancer Care Research Program, Duke University, Durham, North Carolina, USA
    J Pain Palliat Care Pharmacother 23:62-8. 2009
    ....
  101. ncbi request reprint Critical summaries of innovations in palliative care pharmacotherapy
    Amy P Abernethy
    Duke Cancer Care Research Program, Duke University, Durham, North Carolina, USA
    J Pain Palliat Care Pharmacother 25:55-60. 2011
    ....