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Genomes and GenesSpecies | Quan Yang DuhSummaryCountry: USA Publications
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Publications
Adrenal incidentalomasQ-Y Duh
Surgical Service 112, Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, California 94121, USA
Br J Surg 89:1347-9. 2002
What's new in general surgery: endocrine surgeryQuan-Yang Duh
Surgical Service, VA Medical Center, San Francisco, CA 94121, USA
J Am Coll Surg 201:746-53. 2005
Changing paradigms in the treatment of malignant pheochromocytomaRaymon H Grogan
Department of Endocrine Surgery, University of California, San Francisco, CA 94143, USA
Cancer Control 18:104-12. 2011..Recently, however, the genetic and molecular changes involved in malignant pheochromocytoma have come to be understood...
Serum thyroglobulin is a poor diagnostic biomarker of malignancy in follicular and Hurthle-cell neoplasms of the thyroidInsoo Suh
Department of Surgery, University of California San Francisco, 513 Parnassus Ave, San Francisco, CA 94143 0470, USA
Am J Surg 200:41-6. 2010..However, some clinicians measure preoperative Tg as a diagnostic cancer marker despite lack of supporting evidence. We examined whether Tg accurately predicts malignancy in follicular or Hürthle-cell neoplasms...
Parathyroid carcinoma, atypical parathyroid adenoma, or parathyromatosis?Gustavo G Fernandez-Ranvier
Department of Surgery, University of California at San Francisco, San Francisco, California 94143 1674, USA
Cancer 110:255-64. 2007..Parathyroid carcinoma, atypical parathyroid adenoma, and parathyromatosis can be differentiated relatively easily from typical parathyroid adenomas, but distinguishing them from each other is more difficult...
Parathyroid carcinoma: a 43-year outcome and survival analysisAvital Harari
Section of Endocrine Surgery, University of California, Los Angeles, California 90095, USA
J Clin Endocrinol Metab 96:3679-86. 2011..OBJECTIVES AND MAIN OUTCOME MEASURES: The objective of the study was to review the outcomes of parathyroid cancer patients and to evaluate the factors associated with mortality...
Risk assessment in 457 adrenal cortical carcinomas: how much does tumor size predict the likelihood of malignancy?Cord Sturgeon
Department of Surgery, University of California, San Francisco, USA
J Am Coll Surg 202:423-30. 2006..The recent NIH consensus conference did not make a definitive recommendation about management of 4- to 6-cm nonfunctioning incidentalomas...
Id1 gene expression is up-regulated in hyperplastic and neoplastic thyroid tissue and regulates growth and differentiation in thyroid cancer cellsElectron Kebebew
San Francisco Comprehensive Cancer Center, University of California, San Francisco, California 94143 1674, USA
J Clin Endocrinol Metab 89:6105-11. 2004....
Diagnostic and prognostic value of cell-cycle regulatory genes in malignant thyroid neoplasmsElectron Kebebew
San Francisco Comprehensive Cancer Center, University of California, San Francisco, CA 94143 1674, USA
World J Surg 30:767-74. 2006..We hypothesized that genes that regulate cell-cycle progression would be differentially expressed in malignant versus benign thyroid nodules and could serve as diagnostic markers and markers of disease aggressiveness...
The helix-loop-helix protein, Id-1, is overexpressed and regulates growth in papillary thyroid cancerElectron Kebebew
Department of Surgery Department of Pathology, University of California, San Francisco, CA 94143, USA
Surgery 134:235-41. 2003..Furthermore, deregulated expression of Id proteins has been observed in some human malignancies. Therefore we hypothesized that the Id-1 gene may play a role in papillary thyroid carcinogenesis...
ECM1 and TMPRSS4 are diagnostic markers of malignant thyroid neoplasms and improve the accuracy of fine needle aspiration biopsyElectron Kebebew
Endocrine Surgery and Oncology Program, Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA
Ann Surg 242:353-61; discussion 361-3. 2005..The objective of this study was to determine whether genes that regulate cellular invasion and metastasis are differentially expressed and could serve as diagnostic markers of malignant thyroid nodules...
Molecular testing for somatic mutations improves the accuracy of thyroid fine-needle aspiration biopsyWillieford Moses
Department of Surgery, University of California, San Francisco, CA 94143, USA
World J Surg 34:2589-94. 2010..To determine the clinical utility of genetic testing in thyroid FNA biopsy, we conducted a prospective clinical trial...
Diagnostic and prognostic value of angiogenesis-modulating genes in malignant thyroid neoplasmsElectron Kebebew
Endocrine Surgery and Oncology Program, University of California, San Francisco Comprehensive Cancer Center, CA 94143 1674, USA
Surgery 138:1102-9; discussion 1109-10. 2005....
Should pheochromocytoma size influence surgical approach? A comparison of 90 malignant and 60 benign pheochromocytomasWen T Shen
Department of Surgery, University of California San Francisco, Hellman Building C3 47, 1600 Divisadero Street, San Francisco, CA 94143, USA
Surgery 136:1129-37. 2004..The aim of this study was to determine if pheochromocytoma size should affect the choice of surgical approach...
Distinct loci on chromosome 1q21 and 6q22 predispose to familial nonmedullary thyroid cancer: a SNP array-based linkage analysis of 38 familiesInsoo Suh
Department of Surgery, University of California, San Francisco, CA, USA
Surgery 146:1073-80. 2009..We aimed to identify loci linked to FNMTC susceptibility using single-nucleotide polymorphism (SNP) array-based linkage analysis in a broad sampling of affected families...
Does the presence of additional thyroid nodules on ultrasound alter the risk of malignancy in patients with a follicular neoplasm of the thyroid?Rebecca S Sippel
Department of Surgery, University of California San Francisco, and the UCSF Comprehensive Cancer Center at Mount Zion, San Francisco, CA 94143 1674, USA
Surgery 142:851-7; discussion 857.e1-2. 2007..We sought to determine whether the presence of additional thyroid nodules on preoperative ultrasound decreased the risk of malignancy in a patient with a follicular neoplasm...
Modulation of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by chemotherapy in thyroid cancer cell linesJin Woo Park
Department of Surgery, University of California, San Francisco, UCSF Mount Zion Medical Center, San Francisco, California 94143 1674, USA
Thyroid 13:1103-10. 2003..In conclusion, TRAIL in combination with troglitazone, paclitaxel, and cycloheximide induces apoptosis in thyroid cancer cells at suboptimal concentrations that cannot be achieved using TRAIL alone...
Nonfunctioning parathyroid carcinoma: case report and review of literatureGustavo G Fernandez Ranvier
Department of Surgery, University of California, San Francisco, California, USA
Endocr Pract 13:750-7. 2007..To report a case of nonfunctioning parathyroid carcinoma that was incidentally found during a thyroidectomy for multinodular goiter...
Primary hyperparathyroidism patients with positive preoperative sestamibi scan and negative ultrasound are more likely to have posteriorly located upper gland adenomas (PLUGs)Avital Harari
Department of Surgery, University of California, Los Angeles, CA, USA
Ann Surg Oncol 18:1717-22. 2011..In a subset of patients with a positive MIBI and a negative US, we hypothesize that the parathyroid adenomas are more likely to be located posteriorly in the neck, where anatomically they are more difficult to detect by US...
Adrenal incidentaloma: does an adequate workup rule out surprises?Raymon H Grogan
Department of Endocrine Surgery, University of California San Francisco, San Francisco, CA 94143, USA
Surgery 148:392-7. 2010..We sought to determine how accurately these guidelines identify functioning incidentalomas and how often these guidelines result in adrenalectomy for benign tumors...
GCMB gene, a master regulator of parathyroid gland development, expression, and regulation in hyperparathyroidismElectron Kebebew
Department of Surgery, University of California San Francisco, Box 1674, San Francisco, CA 94143, USA
Surgery 136:1261-6. 2004..The glial cell missing gene, GCMB , encodes a transcription factor, which is a master regulator of parathyroid development. We postulated that the GCMB gene might play a role in parathyroid tumorigenesis in hyperparathyroidism...
Multiple genetic alterations in papillary thyroid cancer are associated with younger age at presentationWillieford Moses
Department of Surgery, University of California, San Francisco, California 94143, USA
J Surg Res 160:179-83. 2010..There is a significant gender and age disparity in thyroid cancer incidence and outcome. The molecular basis for these divergent clinical presentations and outcome are essentially unknown...
Candidate genes associated with malignant pheochromocytomas by genome-wide expression profilingInsoo Suh
Department of Surgery, University of California, San Francisco, CA 94143 1674, USA
Ann Surg 250:983-90. 2009..To improve our understanding of the molecular mechanisms involved in malignant pheochromocytoma by examining differences in the gene expression profile between benign and malignant tumors...
Does intraoperative quick parathyroid hormone assay improve the results of parathyroidectomy?Daishu Miura
Department of Surgery, University of California, San Francisco Mount Zion Medical Center, 1600 Divisadero Street, 94143 1674, USA
World J Surg 26:926-30. 2002..Adding qPTH to MIBI or US can improve the success rate but at a significant cost. General exploration of all parathyroid glands, however, has the highest success rate (100%)...
Predictors of single-gland vs multigland parathyroid disease in primary hyperparathyroidism: a simple and accurate scoring modelElectron Kebebew
Comprehensive Cancer Center and Department of Surgery, University of California, San Francisco, USA
Arch Surg 141:777-82; discussion 782. 2006....
Central neck lymph node dissection for papillary thyroid cancer: the reliability of surgeon judgment in predicting which patients will benefitWen T Shen
Department of Surgery, University of California, San Francisco Mt Zion Medical Center, San Francisco, CA 94115, USA
Surgery 148:398-403. 2010..We perform CLND for PTC only in patients with enlarged nodes as determined by preoperative ultrasound and intraoperative inspection and palpation...
Diagnostic and prognostic value of fas and telomeric-repeat binding factor-1 genes in adrenal tumorsHajime Kanauchi
Endocrine Surgical Oncology Fellows, Department of Surgery, University of California San Francisco UCSF, San Francisco, California 94143, USA
J Clin Endocrinol Metab 88:3690-3. 2003..This lack of expression of fas in adrenal cortical cancer may help to distinguish it from benign adrenal tumors. The level of TRF-1 expression may be helpful prognostically for patients with adrenal cortical cancers...
Presidential Address: Minimally invasive endocrine surgery--standard of treatment or hype?Quan Yang Duh
Department of Surgery, University of California San Francisco, 4150 Clement Street, CA 94121, USA
Surgery 134:849-57. 2003
Incision length for standard thyroidectomy and parathyroidectomy: when is it minimally invasive?Laurent Brunaud
Department of Surgery, University of California, San Francisco, USA
Arch Surg 138:1140-3. 2003..Current techniques for open conventional thyroidectomy or parathyroidectomy have evolved to enable a shorter incision (main proposition), and the length of the incision is influenced by objective factors...
The prevalence and prognostic value of BRAF mutation in thyroid cancerElectron Kebebew
Department of Surgery, University of California, San Francisco, San Francisco, California 94143 1674, USA
Ann Surg 246:466-70; discussion 470-1. 2007..To examine the prevalence of BRAF mutation among thyroid cancer histologic subtypes and determine the association of BRAF mutation with indicators of poor prognosis for papillary thyroid cancer and patient outcome...
Extent of disease at presentation and outcome for adrenocortical carcinoma: have we made progress?Electron Kebebew
Department of Surgery, University of California, San Francisco, Box 1674, San Francisco, CA 94143 1674, USA
World J Surg 30:872-8. 2006..Recent studies suggest that this has led to earlier stage of ACC at diagnosis, more curative operations, and better survival...
Tumor size predicts malignant potential in Hürthle cell neoplasms of the thyroidRebecca S Sippel
Department of Surgery, University of California San Francisco and the UCSF Comprehensive Cancer Center at Mount Zion, San Francisco, CA 94143, USA
World J Surg 32:702-7. 2008..We sought to determine if the primary tumor size correlated with the risk of malignancy in patients with a preoperative FNA diagnosis of a Hürthle cell neoplasm...
Malignant pheochromocytomaRasa Zarnegar
Department of Surgery, University California San Francisco, Comprehensive Cancer Center at Mount Zion, Medical Center, 1600 Divisadero Street, Hellman Building, Room C347, San Francisco, CA 94143 1764, USA
Surg Oncol Clin N Am 15:555-71. 2006....
Central neck lymph node dissection for papillary thyroid cancer: comparison of complication and recurrence rates in 295 initial dissections and reoperationsWen T Shen
Department of Surgery, University of California, San Francisco Mt Zion Medical Center, 1600 Divisadero Street, San Francisco, CA 94115, USA
Arch Surg 145:272-5. 2010..Critics of this approach argue that reoperative CLND has higher complication and recurrence rates than initial CLND. We sought to test this argument, using it as our hypothesis...
Successful localization of recurrent thyroid cancer in reoperative neck surgery using ultrasound-guided methylene blue dye injectionAvital Harari
University of California, Los Angeles, Section of Endocrine Surgery, Los Angeles, CA 90095, USA
J Am Coll Surg 215:555-61. 2012..Here we analyze our methylene blue dye injection method to localize reoperative neck pathology in patients with thyroid cancer and lymph node metastases...
Differentiated thyroid cancer cell invasion is regulated through epidermal growth factor receptor-dependent activation of matrix metalloproteinase (MMP)-2/gelatinase AMichael W Yeh
Endocrine Surgery Laboratory, UCSF Mt Zion Medical Center, San Francisco, California 94115, USA
Endocr Relat Cancer 13:1173-83. 2006..MMP inhibitors and growth factor antagonists may be effective tumoristatic agents for the treatment of aggressive thyroid carcinomas...
Observation or laparoscopic adrenalectomy for adrenal incidentaloma? A surgical decision analysisLaurent Brunaud
Department of Surgery, University California San Francisco and Mount Zion Medical Center, Mount Zion Medical Center, San Francisco, CA, USA
Med Sci Monit 12:CR355-62. 2006..A decision analysis model was used to identify relevant variables for selecting the optimal management (observation versus adrenalectomy)...
Parathyroidectomy for primary hyperparathyroidism in octogenarians and nonagenarians: a plea for early surgical referralElectron Kebebew
Department of Surgery, University of California, San Francisco, CA 94143 1674, USA
Arch Surg 138:867-71. 2003....
One hundred two patients with pheochromocytoma treated at a single institution since the introduction of laparoscopic adrenalectomyWen T Shen
University of California San Francisco Mount Zion Medical Center, 1600 Divisadero Street, San Francisco, CA 94115, USA
Arch Surg 145:893-7. 2010..Pheochromocytoma can be safely treated laparoscopically; "subclinical" pheochromocytoma is increasingly common...
Tertiary hyperparathyroidism: histologic patterns of disease and results of parathyroidectomyElectron Kebebew
Department of Surgery, University of California, San Francisco 94143 1674, USA
Arch Surg 139:974-7. 2004..Patients with tertiary hyperparathyroidism (THPT) commonly have parathyroid hyperplasia and should have a bilateral neck exploration with subtotal or total parathyroidectomy with autotransplantation to obtain long-term cure...
Mitogen-inducible gene-6 expression correlates with survival and is an independent predictor of recurrence in BRAF(V600E) positive papillary thyroid cancersDaniel T Ruan
Department of Surgery, University of California, San Francisco, San Francisco, Calif, USA
Surgery 144:908-13; discussion 913-4. 2008..The purpose of this study was to determine if Mig-6 expression is associated with EGFR expression or surgical outcomes in PTC...
Troglitazone, the peroxisome proliferator-activated receptor-gamma agonist, induces antiproliferation and redifferentiation in human thyroid cancer cell linesJin Woo Park
Department of Surgery University of California, San Francisco, UCSF Mount Zion Medical Center, San Francisco, CA 94143, USA
Thyroid 15:222-31. 2005..PPARgamma agonists may therefore be effective therapeutic agents for the treatment of patients with thyroid cancer that fails to respond to traditional treatments...
Differences in metabolic urinary abnormalities in stone forming and nonstone forming patients with primary hyperparathyroidismMathew D Sorensen
Department of Urology, University of California, San Francisco, CA, USA
Surgery 151:477-83. 2012..We evaluated differences between stone formers and non-stone formers in serum and urinary parameters before and after parathyroidectomy...
Clinical spectrum of pheochromocytomaMarlon A Guerrero
Department of Surgery, University of California, 1600 Divisadero St, San Francisco, CA 94115, USA
J Am Coll Surg 209:727-32. 2009..The goal of this study was to determine if tumor size and hormone level correlate according to the clinical presentation at diagnosis...
A phase II trial of rosiglitazone in patients with thyroglobulin-positive and radioiodine-negative differentiated thyroid cancerElectron Kebebew
Department of Surgery, University of California, San Francisco, CA 94143, USA
Surgery 140:960-6; discussion 966-7. 2006..Rosiglitazone is a peroxisome proliferator-activated receptor gamma (PPARgamma) agonist that has been shown to induce differentiation, cell cycle arrest, and apoptosis in a variety of human cancers including thyroid cancer...
Does routine consultation of thyroid fine-needle aspiration cytology change surgical management?Yah Y Tan
Department of Surgery, University of California, San Francisco, San Francisco, CA 94143 1674, USA
J Am Coll Surg 205:8-12. 2007..We sought to determine the concordance rates between FNA interpretations at referring institutions and our center to determine if they alter surgical management...
Parathyroid gland volume increases with postmaturational aging in the ratBernard Halloran
Division of Endocrinology, Veterans Affairs Medical Center and Department of Medicine, University of California, San Francisco, California 94121, USA
Am J Physiol Endocrinol Metab 282:E557-63. 2002..Later in life (>24 mo), the increase in parathyroid cell proliferation rate, further hyperplastic expansion of the gland, and increase in iPTH secretion appear to be associated with renal insufficiency...
Is adrenal venous sampling necessary in all patients with hyperaldosteronism before adrenalectomy?Rasa Zarnegar
Department of Surgery, University of California San Francisco Medical Center, San Francisco, CA, USA
J Vasc Interv Radiol 19:66-71. 2008..To evaluate whether selective rather than universal use of adrenal vein sampling (AVS) may be warranted in patients with hyperaldosteronism to characterize and lateralize disease before adrenalectomy...
Fluorodeoxyglucose-positron emission tomography scan-positive recurrent papillary thyroid cancer and the prognosis and implications for surgical managementJennifer M J Schreinemakers
Department of Surgery, University of California, 1600 Divisadero Street, Box 1711, San Francisco, CA 94115, USA
World J Surg Oncol 10:192. 2012....
The NIH criteria for parathyroidectomy in asymptomatic primary hyperparathyroidism: are they too limited?Monica S Eigelberger
Department of Surgery, University of California, San Francisco, USA
Ann Surg 239:528-35. 2004..To determine whether preoperative and postoperative symptoms and outcome differ in patients who meet or fail to meet the NIH criteria for parathyroidectomy...
Laparoscopic appreciation of the adrenal artery: fact or fiction?Andrew B Joel
Department of Urology, University of California San Francisco, CA 94143, USA
J Endourol 19:793-6. 2005..The surgical and anatomic literature propagates the notion of a dominant or multiple dominant adrenal arteries that should likewise be controlled during surgical extirpation...
Modulation of matrix metalloproteinase activity in human thyroid cancer cell lines using demethylating agents and histone deacetylase inhibitorsElliot J Mitmaker
Department of Surgery, University of California, San Francisco, CA, USA
Surgery 149:504-11. 2011....
Parathyroid surgery: separating promise from realityNancy D Perrier
Department of Surgery, University of California, San Francisco Mount Zion Medical Center, San Francisco, California 94143 1674, USA
J Clin Endocrinol Metab 87:1024-9. 2002..The combination of a solitary hot spot on sestamibi scan and a fall in IOPTH allows the surgeon to make the correct decision regarding the need to convert to a bilateral approach in 93% of these selected patients...
Less-than-subtotal parathyroidectomy increases the risk of persistent/recurrent hyperparathyroidism after parathyroidectomy in tertiary hyperparathyroidism after renal transplantationFrederic Triponez
Division of Endocrine Surgical Oncology, University of California at San Francisco, San Francisco, CA, USA
Surgery 140:990-7; discussion 997-9. 2006..The optimal surgical approach for tertiary hyperparathyroidism (HPT) after kidney transplantation is unknown. Existing studies are limited by small sample size, lack of adjustment for kidney function, and no long-term follow-up...
Medullary thyroid carcinoma manifesting as an ovarian mass: case report and review of literatureJessica E Gosnell
Department of General Surgery, San Mateo Medical Center, San Francisco, California, USA
Endocr Pract 14:351-7. 2008..To report the uncommon case of a woman with abdominal pain and a complex adnexal mass, who was subsequently found to have medullary thyroid carcinoma (MTC) metastatic to the ovary...
Does the 3-gene diagnostic assay accurately distinguish benign from malignant thyroid neoplasms?Daniel Shibru
Department of Surgery, University of California at San Francisco, San Francisco, California 94143 1674, USA
Cancer 113:930-5. 2008..The aim of the current study was to determine the diagnostic accuracy of the 3-gene assay in thyroid tissue and in FNA biopsy for distinguishing benign from malignant thyroid neoplasms...
Prediction of successful outcome in patients with primary aldosteronismTracy Ann Moo
Sergical Service, Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
Curr Treat Options Oncol 8:314-21. 2007..Therefore, it is essential to accurately identify the specific subtype of primary aldosteronism in order to select optimal treatment and to achieve successful patient outcomes...
Oral calcium supplementation associated with decreased likelihood of nephrolithiasis prior to surgery for hyperparathyroidismMatthew R Cooperberg
Department of Urology, University of California, San Francisco, San Francisco, California 94143, USA
Int J Urol 14:1113-5. 2007..027; women 7% vs 17%, P = 0.04). The mechanism for the apparent protective effect of OCS on rates of nephrolithiasis is unclear, and further research is required to elucidate the variable penetrance of nephrolithiasis among PHPT patients...
Hemolysis falsely decreases intraoperative parathyroid hormone levelsJacob Moalem
University of California, San Francisco, CA, USA
Am J Surg 197:222-6. 2009..Falsely decreased IOPTH measurements could result in false-negative or false-positive results and lead to failed parathyroidectomy or unnecessary additional exploration...
Defining a molecular phenotype for benign and malignant parathyroid tumorsGustavo G Fernandez-Ranvier
Department of Surgery, University of California at San Francisco, San Francisco, California 94143 1674, USA
Cancer 115:334-44. 2009....
Treatment and prevention of recurrence of multinodular goiter: an evidence-based review of the literatureJacob Moalem
Endocrine Surgery, University of California, San Francisco, CA 94143, USA
World J Surg 32:1301-12. 2008..Reportedly, 10-15% of patients with goiters ultimately require operative intervention, and recurrences of multinodular goiter (MNG) account for up to 12% of all thyroid operations...
Laparoscopic repair of inguinal herniasJonathan Carter
Department of Surgery, UCSF, 521 Parnassus Ave C347, San Francisco, CA 94143 0790, USA
World J Surg 35:1519-25. 2011..For others, the best technique remains the approach that the surgeon is most comfortable and experienced performing...
Laparoscopic enucleation of insulinomasMatthew P Sweet
Surgical Service, Veterans Affairs Medical Center, 4150 Clement St, San Francisco, CA 94121, USA
Arch Surg 142:1202-4; discussion 1205. 2007..Laparoscopic enucleation of insulinomas is safe and effective and is associated with a short hospital stay...
Reoperation for adrenocortical neoplasmsJames A Lee
Department of Surgery, San Francisco Medical Center, University of California, 4150 Clement Street, 94121, USA
Curr Treat Options Oncol 7:320-5. 2006..Multiple promising treatments such as radiofrequency ablation, tyrosine kinase inhibitors, and competitive inhibitors of multidrug resistance gene products are in preclinical trials and may improve patient outcomes...
Comparison of clinical characteristics at diagnosis and during follow-up in 118 patients with Hurthle cell or follicular thyroid cancerYevgeniya Kushchayeva
Department of Surgery, University of California San Francisco, UCSF Mt Zion Medical Center, 1600 Divisadero Street C347, San Francisco, CA 94143 1674, USA
Am J Surg 195:457-62. 2008..Hurthle cell cancer (HCC) is considered by some to be a variant of follicular cancer (FC), but many think it is a distinct histologic tumor with a more aggressive behavior...
Patients with primary hyperparathyroidism--why do some form stones?Aaron D Berger
Department of Urology, University of California San Francisco, San Francisco, California, USA
J Urol 181:2141-5. 2009..We evaluated the metabolic stone profile in patients presenting for parathyroid surgery and determined whether there were differences between those with and without a history of urinary stones...
Recent advances in minimally invasive endocrine surgeryQuan-Yang Duh
Department of Surgery, UCSF Advanced Videoscopic Surgery Center, University of California, San Francisco, CA, USA
Asian J Surg 26:62-3. 2003
Intraoperative parathyroid hormone assay and parathyroid reoperationsFrederic Sebag
Department of Endocrine Surgery, Mount Zion Hospital, 1600 Divisidero Street, San Francisco, CA 94143-1674, USA
Surgery 134:1049-55; discussion 1056. 2003..CONCLUSIONS: IOPTH testing was relatively reliable in patients with persistent or recurrent sporadic primary hyperparathyroidism, but the test unfortunately failed to improve the overall success rate at reoperation...
Predictors of airway complications after thyroidectomy for substernal goiterWen T Shen
Department of Surgery, University of California, San Francisco, USA
Arch Surg 139:656-9; discussion 659-60. 2004..The few patients who developed postoperative airway complications were older, had larger goiters, and were more likely to have tracheal compression on preoperative imaging than those without airway complications...
Prognostic indications for Hürthle cell cancerYevgeniya Kushchayeva
Endocrine Surgical Oncology, Department of Surgery, University of California-San Francisco/Mount Zion Medical Center, 1600 Divisadero Street, San Francisco, CA 94143-1674, USA
World J Surg 28:1266-70. 2004..Disease-free survivals were 65.0% and 40.5% at 5 and 10 years, respectively. Our findings show that gender and stage of disease influence the prognosis of patients with HCC...
Accuracy of preoperative localization studies and intraoperative parathyroid hormone assay in patients with primary hyperparathyroidism and double adenomaMehmet Haciyanli
Department of Surgery, University of California San Francisco/Mount Zion Medical Center, San Francisco, CA, USA
J Am Coll Surg 197:739-46. 2003..The combined accuracy of US, sestamibi, and IOPTH assay predicted a double adenoma in 80% of the patients...
Use of the electrothermal vessel sealing system versus standard vessel ligation in thyroidectomyWen T Shen
Department of Surgery, San Francisco Veterans Affairs Medical Center, San Francisco, California 94121, USA
Asian J Surg 28:86-9. 2005..CONCLUSION: We found that the LigaSure was as safe as standard vessel ligation for thyroidectomy, with the benefit of reduced operating time. A future prospective study has been designed...
Differing histologic findings after bilateral and focused parathyroidectomyHudai Genc
Department of Surgery, Mount Zion Medical Center, University of California at San Francisco, 1600 Divisadero Street, San Francisco, CA 94143-1674, USA
J Am Coll Surg 196:535-40. 2003..Longterm followup will be necessary to determine whether patients treated by focal neck exploration will develop recurrent primary hyperparathyroidism...
Complications of neck dissection for thyroid cancerW Keat Cheah
Department of Surgery, University of California, San Francisco/Mt. Zion Medical Center, 1600 Divisadero Street, 94143-1674, USA
World J Surg 26:1013-6. 2002..Therapeutic neck dissection or repeated neck dissection can be performed relatively safely in patients with thyroid cancer. Hypocalcemia occurs most frequently when neck dissection is combined with total thyroidectomy...
Lung transplantation for pulmonary metastases and radiation-induced pulmonary fibrosis after radioactive iodine ablation of extensive lung metastases from papillary thyroid carcinomaJames Lee
Endocrine Surgery Department, University of California, San Francisco, California, USA
Thyroid 17:367-9. 2007
Adrenal incidentaloma, borderline elevations of urine or plasma metanephrine levels, and the "subclinical" pheochromocytomaJames A Lee
Division of Gastrointestinal Endocrine Surgery, Columbia University Medical Center, New York, New York, USA
Arch Surg 142:870-3; discussion 73-4. 2007..To assess the risk of pheochromocytoma in patients with borderline-elevated urine or plasma metanephrine levels...
From incidentaloma to adrenocortical carcinoma: the surgical management of adrenal tumorsWen T Shen
Department of Surgery, University of California, San Francisco, California, USA
J Surg Oncol 89:186-92. 2005..We also discuss the choice of optimal surgical approach for performing adrenalectomy (laparoscopic, open, hand-assist)...
Lymph node metastasis from 259 papillary thyroid microcarcinomas: frequency, pattern of occurrence and recurrence, and optimal strategy for neck dissectionNobuyuki Wada
First Department of Surgery, Yokohama City University School of Medicine, Yokohama, Kanagawa, Japan
Ann Surg 237:399-407. 2003..CONCLUSIONS: Patients who have PTMC presenting with palpable lymphadenopathy should have therapeutic node dissection. Prophylactic node dissection is not beneficial in those without palpable lymphadenopathy...
Resecting isolated adrenal metastasis: why and how?Quan Yang Duh
Ann Surg Oncol 10:1138-9. 2003
AldosteronomaLaurent Brunaud
Department of Surgery, University of California, San Francisco/Mount Zion Medical Center, 94143-1674, USA
Curr Treat Options Oncol 3:327-33. 2002..Focused approach and laparoscopic resection are the norm for the surgical treatment of aldosteronoma...
Results of laparoscopic adrenalectomy for suspected and unsuspected malignant adrenal neoplasmsElectron Kebebew
Department of Surgery, University of California, San Francisco 94121, USA
Arch Surg 137:948-51; discussion 952-3. 2002..Furthermore, preoperative fine-needle aspiration cytology for the evaluation of suspected malignant adrenal tumors is unreliable...
Apoptosis regulating genes, bcl-2 and bax, and human telomerase reverse transcriptase messenger RNA expression in adrenal tumors: possible diagnostic and prognostic importanceHajime Kanauchi
Department of Surgery, University of California San Francisco/Mount Zion Medical Center, 1600 Divisadero Street, Room 437, San Francisco, CA 94143-1674, USA
Surgery 132:1021-6; discussion 1026-7. 2002..CONCLUSIONS: Expression of bax gene appears to distinguish adrenal cancer from benign adrenal tumors. Gene expression of hTERT should be investigated as a prognostic marker in adrenal cortical cancers...
Laparoscopic adrenalectomy--indications and techniqueGeeta Lal
UCSF/Mt. Zion Medical Center, 1600 Divisadero Street, suite c347, San Francisco, CA 94143-1674, USA
Surg Oncol 12:105-23. 2003..This review discusses the indications and contraindications, technique and outcomes for laparoscopic adrenalectomy...
VEGF-mediated angiogenesis of human pheochromocytomas is associated to malignancy and inhibited by anti-VEGF antibodies in experimental tumorsAndreas Zielke
Department of Surgery, Philipps-University of Marburg, 35043 Marburg, Germany
Surgery 132:1056-63; discussion 1063. 2002..Angiogenesis of PC12 xenografts is mediated by VEGF. Neutralizing anti-VEGF antibodies inhibit angiogenesis in experimental pheochromocytomas and may have potential for treating nonresectable pheochromocytomas...
New approaches to the minimally invasive treatment of adrenal lesionsJennifer Braemar Ogilvie
Department of Surgery, University of California, San Francisco, 94121, USA
Cancer J 11:64-72. 2005..Experienced surgeons now resect some malignant tumors laparoscopically, with the option to convert to a hand-assisted or traditional open approach...
Thyroid cancer in Graves disease: incidental cancer versus clinical cancerQuan-Yang Duh
Ann Surg Oncol 11:356-7. 2004
Clinical manifestation of aldosteronomaMaha Al Fehaily
Department of Surgery, University of Toronto, 100 College Street, Toronto, ON, M5G 1L5, Canada
Surg Clin North Am 84:887-905. 2004..Excess aldosterone level has a deleterious effect on the cardiovascular system. Aldosteronomas should be differentiated from idiopathic hyperaldosteronism (IHA),because they are curable by laparoscopic adrenalectomy...
Laparoscopic adrenalectomy for isolated adrenal metastasis: the right thing to do and the right way to do itQuan-Yang Duh
Ann Surg Oncol 14:3288-9. 2007
Sporadic paragangliomaJames A Lee
Department of Surgery, Columbia University Medical Center, 161 Fort Washington Avenue, New York, New York 10032, USA
World J Surg 32:683-7. 2008..Favorably located abdominal paragangliomas can be safely resected laparoscopically, but the operation is technically more challenging than that for adrenalectomy...
Laparoscopic adrenalectomy after prior abdominal surgeryLilah Morris
Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
World J Surg 32:897-903. 2008..Some regard prior abdominal surgery as a contraindication to LA or suggest a retroperitoneoscopic approach. We studied the effect of prior abdominal surgery on the feasibility and safety of transabdominal LA...
Primary malignant fibrous histiocytoma of the thyroid: review of the literature with two new casesKuo Feng Hsu
Division of General Surgery, Department of Surgery, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
Thyroid 18:51-5. 2008..Neither patient had metastatic lesions found by whole body gallium scans, computerized tomographic scans, and neck sonography. Both patients had postoperative radiotherapy and were alive and without recurrence at 6 months follow-up...
Selective use of adrenal venous sampling in the lateralization of aldosterone-producing adenomasYah Yuen Tan
Department of Surgery, University of California San Francisco, 4150 Clement Street, San Francisco, California 94121, USA
World J Surg 30:879-85; discussion 886-7. 2006..This practice in our center has resulted in high cure rates. During the era of improved imaging resolution and experience, mandatory routine AVS is not necessary to achieve high cure rates for aldosteronomas...
The aldosteronoma resolution score: predicting complete resolution of hypertension after adrenalectomy for aldosteronomaRasa Zarnegar
Department of Surgery, Weill Cornell Medical College, New York, NY 10021, USA
Ann Surg 247:511-8. 2008..To develop a prediction model using information readily available, at clinical presentation, which could determine whether patients with aldosterone-producing adenomas would have complete resolution of hypertension after adrenalectomy...
Should total thyroidectomy become the preferred procedure for surgical management of Graves' disease?Geeta Lal
Department of Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
Thyroid 15:569-74. 2005..Total or near-total thyroidectomy obviates these disadvantages and can be performed without increased complication rates, thus appearing to be the preferred extent of thyroidectomy for Graves' disease...
Thyroidectomy for Hashimoto's thyroiditis: complications and associated cancersMing Lang Shih
Division of General Surgery, Department of Surgery, National Defense Medical Center, Taipei, Taiwan, R O C
Thyroid 18:729-34. 2008..The aim of this study was to determine the rate of complications and associated cancer in patients with Hashimoto's thyroiditis...
Complication of thyroidectomy in patients with radiation-induced thyroid neoplasmsShoichi Kikuchi
National Defense Medical College, Kushiro, Japan
Arch Surg 139:1185-8. 2004..The relatively low long-term complication rate supports prophylactic total thyroidectomy for patients with thyroid nodules and a history of radiation exposure...
Reasons for conversion from laparoscopic to open or hand-assisted adrenalectomy: review of 261 laparoscopic adrenalectomies from 1993 to 2003Wen T Shen
Department of Surgery, University of California, San Francisco/Mt Zion Medical Center, San Francisco, California 94143-1674, USA
World J Surg 28:1176-9. 2004..All eight of the tumors removed were at least 5 cm in size (range 5-16 cm). The mean length of hospitalization was 4.4 days (range 3-8 days)...
Laparoscopic surgery for melanoma metastases to the adrenal glandCord Sturgeon
University of Feinberg School of Medicine, Division of Gastrointestinal and Endocrine Surgery, Chicago, IL 60611 2908, USA
Expert Rev Anticancer Ther 4:837-41. 2004..However, the natural history of laparoscopic surgery for these lesions is still unknown. The indications for and limitations of laparoscopic adrenalectomy for metastatic melanoma are discussed...
Laparoscopic adrenalectomy for pheochromocytomaW Keat Cheah
Department of Surgery, University of California San Francisco, Veterans Affairs Medical Center, 4150 Clement Street, 94121, USA
World J Surg 26:1048-51. 2002..Laparoscopic adrenalectomy is the preferred surgical approach for patients with pheochromocytoma because it is safe and efficacious...
