Affiliation: Drexel University
- Influence of vortex speed on fresh versus stored platelet aggregation in the absence and presence of extracellular ATPG Soslau
Department of Biochemistry, MCP Hahnemann School of Medicine, Philadelphia, Pennsylvania 19102 1192, USA
Thromb Res 97:15-27. 2000..Unraveling how hemostasis functions within microenvironments may facilitate ways to further regulate this process...
- Comparison of functional aspects of the coagulation cascade in human and sea turtle plasmasGerald Soslau
Department of Biochemistry, Drexel University College of Medicine, Philadelphia, PA 19102, USA
Comp Biochem Physiol B Biochem Mol Biol 138:399-406. 2004..These comparative studies of the coagulation pathway in sea turtles and humans could enhance our knowledge of structure/function relationships and evolution of coagulation factors...
- Extracellular ATP inhibits agonist-induced mobilization of internal calcium in human plateletsG Soslau
Department of Biological Chemistry, Hahnemann University, Philadelphia, PA 19102, USA
Biochim Biophys Acta 1268:73-80. 1995..ATP, released from activated platelets at localized sites of vascular injury, may help to limit the size of the platelet plug-clot that, if left unregulated, could occlude the injured blood vessel...
- Occupancy of P2 purinoceptors with unique properties modulates the function of human plateletsG Soslau
Department of Biochemistry, Hahnemann University School of Medicine, Philadelphia, PA 19102 1192
Biochim Biophys Acta 1177:199-207. 1993..This implies that the generation of cyclic AMP, with the subsequent activation of PKA and phosphorylation of selected proteins is required, in part, for the action of ATP...
- Unique pathway of thrombin-induced platelet aggregation mediated by glycoprotein IbG Soslau
Department of Biochemistry, Division of Hematology/Oncology, MCP Hahnemann School of Medicine, Philadelphia, Pennsylvania 19102, USA
J Biol Chem 276:21173-83. 2001..The presence of the GP Ib pathway may explain why anti-alpha-thrombin/anti-platelet regimens fail to completely abrogate thrombosis/restenosis in the cardiac patient...
- A possible dual physiological role of extracellular ATP in the modulation of platelet aggregationG Soslau
Department of Biochemistry, Medical College of Pennsylvania, Philadelphia, USA
Biochim Biophys Acta 1355:131-40. 1997..The dual response of platelets to low and high concentrations of extracellular ATP +/- ADP may play a physiological role in hemostasis and thrombosis under normal and pathological conditions...
- A micromethod to measure platelet aggregation and atp release by impedanceS J Goldenberg
Department of Biomedical Science, Drexel University, Philadelphia, PA 19104, USA
Thromb Res 103:57-61. 2001..This electrode is well suited for evaluation of platelet function in research and clinical blood samples where only small volumes of blood are available...
- Comparison of sea turtle thrombocyte aggregation to human platelet aggregation in whole bloodGerald Soslau
Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, 245 N 15th Street, MS 344, Philadelphia, PA 19102, USA
Comp Biochem Physiol B Biochem Mol Biol 142:353-60. 2005..Comparison of hemostasis in sea turtles to other vertebrates could provide a framework for understanding the structure/function and evolution of these pathways and their individual components...
- Cytokine mediated proliferation of cultured sea turtle blood cells: morphologic and functional comparison to human blood cellsDoris A Morgan
Department of Medicine, Division of Hematology Oncology, Drexel University College of Medicine, 245N Fifteenth Street, Philadelphia, PA 19102, USA
Tissue Cell 41:299-309. 2009....