ALEISTER SAUNDERS

Summary

Affiliation: Drexel University
Country: USA

Publications

  1. pmc A streamlined sub-cloning procedure to transfer shRNA from a pSM2 vector to a pGIPZ lentiviral vector
    Sara Ansaloni
    Department of Biology, Drexel University, Philadelphia, PA, USA
    J RNAi Gene Silencing 6:411-5. 2010
  2. pmc TrkB Isoforms Differentially Affect AICD Production through Their Intracellular Functional Domains
    Sara Ansaloni
    Department of Biology, Drexel University, Philadelphia, PA 19027, USA
    Int J Alzheimers Dis 2011:729382. 2011
  3. pmc Characterization of a Drosophila Alzheimer's disease model: pharmacological rescue of cognitive defects
    Ranjita Chakraborty
    Department of Biology, Drexel University, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 6:e20799. 2011
  4. pmc An AICD-based functional screen to identify APP metabolism regulators
    Can Zhang
    Department of Bioscience and Biotechnology, Drexel University, Philadelphia, PA, USA
    Mol Neurodegener 2:15. 2007
  5. pmc MicroRNAs can regulate human APP levels
    Neha Patel
    Department of Bioscience and Biotechnology, Drexel University, Philadelphia, PA, USA
    Mol Neurodegener 3:10. 2008

Research Grants

Collaborators

  • Jack T Rogers
  • Sara Ansaloni
  • Ranjita Chakraborty
  • Jeremy C Lee
  • Neha Patel
  • Can Zhang
  • Lee E Goldstein
  • Marianna Vinokur
  • Sean Miller
  • Vidya Vepuri
  • Preeti Khandelwal
  • David J Melicharek
  • Rohini Samudralwar
  • Brie E Paddock
  • Brian P Leung
  • Daniel R Marenda
  • Radha Delvadia
  • Robert D Moir
  • Siddhita D Mhatre
  • Suruchi Utreja
  • Mariana Gadaleta
  • Loni P Tabb
  • Neeraj P Sebastian
  • Arkit Desai
  • Sarah J Michelson
  • Jonathan Snyder
  • Charles Epstein
  • Nadav Lelkes
  • Aditi Dubey
  • David Hoang
  • Qihong Huang
  • Nathan Miller
  • MICHAEL O'CONNOR
  • Christopher P Cosentino
  • Rudolph E Tanzi
  • Srikant Sarangi
  • Shyam A Patel
  • Trinna L Cuellar
  • Preeti J Khandelwal

Detail Information

Publications5

  1. pmc A streamlined sub-cloning procedure to transfer shRNA from a pSM2 vector to a pGIPZ lentiviral vector
    Sara Ansaloni
    Department of Biology, Drexel University, Philadelphia, PA, USA
    J RNAi Gene Silencing 6:411-5. 2010
    ....
  2. pmc TrkB Isoforms Differentially Affect AICD Production through Their Intracellular Functional Domains
    Sara Ansaloni
    Department of Biology, Drexel University, Philadelphia, PA 19027, USA
    Int J Alzheimers Dis 2011:729382. 2011
    ..In conclusion, we demonstrated that TrkB isoforms have differential effects on APP metabolism...
  3. pmc Characterization of a Drosophila Alzheimer's disease model: pharmacological rescue of cognitive defects
    Ranjita Chakraborty
    Department of Biology, Drexel University, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 6:e20799. 2011
    ..Taken together these data demonstrate that this transgenic AD model can serve as a powerful tool for the identification of AD therapeutic interventions...
  4. pmc An AICD-based functional screen to identify APP metabolism regulators
    Can Zhang
    Department of Bioscience and Biotechnology, Drexel University, Philadelphia, PA, USA
    Mol Neurodegener 2:15. 2007
    ..Production of AICD-Gal4 induces Gal4-UAS driven luciferase expression. Therefore, when regulators of APP metabolism are modulated, luciferase expression is altered...
  5. pmc MicroRNAs can regulate human APP levels
    Neha Patel
    Department of Bioscience and Biotechnology, Drexel University, Philadelphia, PA, USA
    Mol Neurodegener 3:10. 2008
    ..These results are the first to demonstrate that levels of human APP can be regulated by miRNAs...

Research Grants2

  1. Identification and Characterization of APP Metabolism Regulators
    ALEISTER SAUNDERS; Fiscal Year: 2009
    ..Here we propose to identify the defects that are responsible for this abnormal accumulation. If we can accomplish this we may find new ways to treat Alzheimer's disease. ..
  2. Identification and Characterization of APP Metabolism Regulators
    Aleister J Saunders; Fiscal Year: 2010
    ..Here we propose to identify the defects that are responsible for this abnormal accumulation. If we can accomplish this we may find new ways to treat Alzheimer's disease. ..