Research Topics
| I A RybakSummaryAffiliation: Drexel University Country: USA Publications
| Collaborators |
Detail Information
Publications
Sodium currents in neurons from the rostroventrolateral medulla of the ratIlya A Rybak
School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania 19104, USA
J Neurophysiol 90:1635-42. 2003....
Endogenous rhythm generation in the pre-Bötzinger complex and ionic currents: modelling and in vitro studiesIlya A Rybak
School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, USA
Eur J Neurosci 18:239-57. 2003..These findings are discussed in the context of the role of endogenous bursting activity in the respiratory rhythm generation in vivo vs. in vitro and during normal breathing in vivo vs. gasping...
Intrinsic bursting activity in the pre-Bötzinger complex: role of persistent sodium and potassium currentsIlya A Rybak
School of Biomedical Engineering, Drexel University, Science and Health Systems, Philadelphia, PA 19104, USA
Biol Cybern 90:59-74. 2004..These findings are discussed in the context of the possible role of population bursting activity in the pBC in the respiratory rhythm generation in vivo vs. in vitro and during normal breathing in vivo vs. gasping...
Modeling the ponto-medullary respiratory networkI A Rybak
School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, USA
Respir Physiol Neurobiol 143:307-19. 2004....
Reconfiguration of the pontomedullary respiratory network: a computational modeling study with coordinated in vivo experimentsI A Rybak
Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, USA
J Neurophysiol 100:1770-99. 2008..g., during recovery from severe brain hypoxia, components of a distributed network activity present during eupnea can be co-expressed with gasp patterns generated by a distinct, functionally "simplified" mechanism...
Spatial organization and state-dependent mechanisms for respiratory rhythm and pattern generationIlya A Rybak
Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA
Prog Brain Res 165:201-20. 2007..The model predicts a continuum of respiratory network states relying on different contributions of intrinsic cellular properties versus synaptic interactions for the generation and control of the respiratory rhythm and pattern...
Modelling spinal circuitry involved in locomotor pattern generation: insights from deletions during fictive locomotionIlya A Rybak
Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA
J Physiol 577:617-39. 2006..The model also suggests criteria for the functional identification of spinal interneurones involved in the mammalian locomotor pattern generation...
Modelling spinal circuitry involved in locomotor pattern generation: insights from the effects of afferent stimulationIlya A Rybak
Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA
J Physiol 577:641-58. 2006..The results of modelling provide insights into proprioceptive control of locomotion...
Respiratory rhythm entrainment by somatic afferent stimulationJeffrey T Potts
Department of Physiology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
J Neurosci 25:1965-78. 2005....
Modelling respiratory rhythmogenesis: focus on phase switching mechanismsIlya A Rybak
School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, USA
Adv Exp Med Biol 551:189-94. 2004
Potential switch from eupnea to fictive gasping after blockade of glycine transmission and potassium channelsWalter M St -John
Department of Physiology, Dartmouth Medical School, Lebanon, New Hampshire 03756, USA
Am J Physiol Regul Integr Comp Physiol 283:R721-31. 2002..Results are consistent with the concept that the elicitation of gasping represents a switch from a network-based rhythmogenesis for eupnea to a pacemaker-driven mechanism...
Ionic currents and endogenous rhythm generation in the pre-Bötzinger complex: modelling and in vitro studiesOlivier Pierrefiche
GRAP-JE-UFR de Pharmacie, 80036 Amiens, France
Adv Exp Med Biol 551:121-6. 2004
Modeling the mammalian locomotor CPG: insights from mistakes and perturbationsDavid A McCrea
Spinal Cord Research Centre and Department of Physiology, University of Manitoba, Winnipeg, MB, R3E 3J7, Canada
Prog Brain Res 165:235-53. 2007..The model provides a basis for functional identification of spinal interneurons involved in generation and control of the locomotor pattern...
Organization of mammalian locomotor rhythm and pattern generationDavid A McCrea
Spinal Cord Research Centre and Department of Physiology, University of Manitoba, 730 William Avenue, Winnipeg, Manitoba R3E 3J7, Canada
Brain Res Rev 57:134-46. 2008..Some modeling predictions and directions for further studies of locomotor CPG organization are discussed...
Influence of levels of carbon dioxide and oxygen upon gasping in perfused rat preparationWalter M St -John
Dartmouth Hitchcock Medical Center, Department of Physiology, Dartmouth Medical School, Borwell Building, Lebanon, NH 03756, USA
Respir Physiol 129:279-87. 2002..This release is caused by cellular mechanisms that change the balance between membrane ionic currents. Moreover, these cellular mechanisms may be explicitly induced by alterations in the ionic and metabolic homeostasis...
