Joann M Moulds

Summary

Affiliation: Drexel University
Country: USA

Publications

  1. ncbi Molecular identification of Knops blood group polymorphisms found in long homologous region D of complement receptor 1
    J M Moulds
    University of Texas Houston Medical School, USA
    Blood 97:2879-85. 2001
  2. ncbi Expansion of the Knops blood group system and subdivision of Sl(a)
    J M Moulds
    Department of Microbiology and Immunology, MCP Hahnemann University School of Medicine, Philadelphia, Pennsylvania 19129, USA
    Transfusion 42:251-6. 2002
  3. pmc Identification of the Kna/Knb polymorphism and a method for Knops genotyping
    J M Moulds
    Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania 19129, USA
    Transfusion 44:164-9. 2004
  4. ncbi Understanding the Knops blood group and its role in malaria
    Joann M Moulds
    MCP Hahnemann University School of Medicine, Dept of Microbiology and Immunology, Philadelphia, PA, USA
    Vox Sang 83:185-8. 2002
  5. doi A novel JKA allele, nt561C>A, associated with silencing of Kidd expression
    Trina Horn
    National Molecular Blood Group and Platelet Antigen Testing Laboratory, American Red Cross, Philadelphia, PA, USA
    Transfusion 52:1092-6. 2012
  6. ncbi The molecular genetics of the human I locus and molecular background explain the partial association of the adult i phenotype with congenital cataracts
    Lung Chih Yu
    Transfusion Medicine Laboratory, Mackay Memorial Hospital, and the Institute of Biochemical Sciences, College of Science, National Taiwan University, Taipei, Taiwan
    Blood 101:2081-8. 2003
  7. pmc RHD allele distribution in Africans of Mali
    Franz F Wagner
    Department of Transfusion Medicine, University Hospital, Ulm, Germany
    BMC Genet 4:14. 2003
  8. ncbi Human complement receptor type 1 (CR1) binds to a major malarial adhesin
    Malgorzata Krych-Goldberg
    Division of Rheumatology, Washington University School of Medicine, St Louis, MO 63110, USA
    Trends Mol Med 8:531-7. 2002
  9. ncbi The molecular basis of complete complement C4A and C4B deficiencies in a systemic lupus erythematosus patient with homozygous C4A and C4B mutant genes
    Kristi L Rupert
    Children s Research Institute, Department of Pediatrics and Ohio State Biochemistry Program, Ohio State University, Columbus, OH 43205, USA
    J Immunol 169:1570-8. 2002
  10. pmc Complement receptor 1 polymorphisms associated with resistance to severe malaria in Kenya
    Vandana Thathy
    The US Army Medical Research Unit, The Kenya Medical Research Institute, Nairobi, Kenya
    Malar J 4:54. 2005

Collaborators

Detail Information

Publications14

  1. ncbi Molecular identification of Knops blood group polymorphisms found in long homologous region D of complement receptor 1
    J M Moulds
    University of Texas Houston Medical School, USA
    Blood 97:2879-85. 2001
    ..These data further explain the variability observed in previous serologic studies of CR1 and show that DNA and protein-based genetic studies will be needed to clarify the role of the KN antigens in malaria...
  2. ncbi Expansion of the Knops blood group system and subdivision of Sl(a)
    J M Moulds
    Department of Microbiology and Immunology, MCP Hahnemann University School of Medicine, Philadelphia, Pennsylvania 19129, USA
    Transfusion 42:251-6. 2002
    ..As a first step in understanding this interaction, the molecular basis for the blood group antigens encoded by CR1 was investigated...
  3. pmc Identification of the Kna/Knb polymorphism and a method for Knops genotyping
    J M Moulds
    Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania 19129, USA
    Transfusion 44:164-9. 2004
    ..The molecular identification of the Kna/Knb polymorphism was sought to develop a genotyping method for use in the study of the Knops blood group and malaria...
  4. ncbi Understanding the Knops blood group and its role in malaria
    Joann M Moulds
    MCP Hahnemann University School of Medicine, Dept of Microbiology and Immunology, Philadelphia, PA, USA
    Vox Sang 83:185-8. 2002
    ..Its further role in protein (CR1) function and autoimmune diseases remains unknown but may provide interesting work for years to come...
  5. doi A novel JKA allele, nt561C>A, associated with silencing of Kidd expression
    Trina Horn
    National Molecular Blood Group and Platelet Antigen Testing Laboratory, American Red Cross, Philadelphia, PA, USA
    Transfusion 52:1092-6. 2012
    ..We determined the molecular basis for Jk(a-b-) in an African American family. DNA testing of samples from random African American, Caucasian, and Brazilian blacks was done to estimate the allele frequency...
  6. ncbi The molecular genetics of the human I locus and molecular background explain the partial association of the adult i phenotype with congenital cataracts
    Lung Chih Yu
    Transfusion Medicine Laboratory, Mackay Memorial Hospital, and the Institute of Biochemical Sciences, College of Science, National Taiwan University, Taipei, Taiwan
    Blood 101:2081-8. 2003
    ..The results also suggest that the human blood group I gene should be reassigned to the IGnTC form, not the IGnTB form, as described previously...
  7. pmc RHD allele distribution in Africans of Mali
    Franz F Wagner
    Department of Transfusion Medicine, University Hospital, Ulm, Germany
    BMC Genet 4:14. 2003
    ..The DAU cluster of RHD alleles exemplifies that the alleles frequent in Africans have evaded recognition until recently. A comprehensive survey of RHD alleles in any African population was lacking...
  8. ncbi Human complement receptor type 1 (CR1) binds to a major malarial adhesin
    Malgorzata Krych-Goldberg
    Division of Rheumatology, Washington University School of Medicine, St Louis, MO 63110, USA
    Trends Mol Med 8:531-7. 2002
    ..Furthermore, structural differences in erythrocyte CR1 between human and non-human primates are probably explained by the selective pressure of malaria...
  9. ncbi The molecular basis of complete complement C4A and C4B deficiencies in a systemic lupus erythematosus patient with homozygous C4A and C4B mutant genes
    Kristi L Rupert
    Children s Research Institute, Department of Pediatrics and Ohio State Biochemistry Program, Ohio State University, Columbus, OH 43205, USA
    J Immunol 169:1570-8. 2002
    ..Hence, complete C4 deficiency is one of the most penetrant genetic risk factors for human systemic lupus erythematosus...
  10. pmc Complement receptor 1 polymorphisms associated with resistance to severe malaria in Kenya
    Vandana Thathy
    The US Army Medical Research Unit, The Kenya Medical Research Institute, Nairobi, Kenya
    Malar J 4:54. 2005
    ....
  11. pmc A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria
    Ian A Cockburn
    Institute of Cell Animal and Population Biology, Ashworth Laboratories, King s Buildings, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, United Kingdom
    Proc Natl Acad Sci U S A 101:272-7. 2004
    ..We have therefore identified CR1 as a new malaria resistance gene and provided compelling evidence that rosetting is an important parasite virulence phenotype that should be a target for drug and vaccine development...
  12. ncbi Lack of the Cromer antigen GUTI in Mexican Americans and Choctaw Indians
    Joann M Moulds
    Transfusion 44:307. 2004
  13. ncbi Genetic mechanisms of Rhesus box variation
    Franz F Wagner
    Department of Transfusion Medicine, University Hospital, Ulm, Germany
    Transfusion 45:338-44. 2005
    ..Aberrant Rhesus boxes can confound this application and appear to be frequent among African individuals...
  14. pmc Blood group O protects against severe Plasmodium falciparum malaria through the mechanism of reduced rosetting
    J Alexandra Rowe
    Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, United Kingdom
    Proc Natl Acad Sci U S A 104:17471-6. 2007
    ..falciparum rosetting. This work provides insights into malaria pathogenesis and suggests that the selective pressure imposed by malaria may contribute to the variable global distribution of ABO blood groups in the human population...