Phillip E Funk

Summary

Affiliation: DePaul University
Country: USA

Publications

  1. ncbi Dynamic control of B lymphocyte development in the bursa of fabricius
    Phillip E Funk
    Department of Biological Sciences, DePaul University, Chicago, IL 60614, USA
    Arch Immunol Ther Exp (Warsz) 51:389-98. 2003
  2. ncbi The avian chB6 alloantigen induces apoptosis in DT40 B cells
    Phillip E Funk
    Department of Biological Sciences, DePaul University, 2325 N Clifton, Chicago, IL 60614, USA
    Cell Immunol 226:95-104. 2003
  3. ncbi The avian ChB6 alloantigen triggers apoptosis in a mammalian cell line
    Jeannette Pifer
    Department of Biological Sciences, DePaul University, Chicago, IL 60614, USA
    J Immunol 169:1372-8. 2002

Research Grants

  1. Avian chB6 Alloantigen in Apoptosis
    PHILLIP FUNK; Fiscal Year: 2003

Collaborators

  • Jeannette Pifer
  • Donald Robison

Detail Information

Publications3

  1. ncbi Dynamic control of B lymphocyte development in the bursa of fabricius
    Phillip E Funk
    Department of Biological Sciences, DePaul University, Chicago, IL 60614, USA
    Arch Immunol Ther Exp (Warsz) 51:389-98. 2003
    ..Our recent work on chB6 will be presented and placed in the context of other recent studies of B cell development in the bursa...
  2. ncbi The avian chB6 alloantigen induces apoptosis in DT40 B cells
    Phillip E Funk
    Department of Biological Sciences, DePaul University, 2325 N Clifton, Chicago, IL 60614, USA
    Cell Immunol 226:95-104. 2003
    ..Collectively these data argue that chB6 may function as a novel death receptor on avian B-lymphocytes and support the use of DT40 as an amenable model to study the signaling involved in chB6-induced apoptosis...
  3. ncbi The avian ChB6 alloantigen triggers apoptosis in a mammalian cell line
    Jeannette Pifer
    Department of Biological Sciences, DePaul University, Chicago, IL 60614, USA
    J Immunol 169:1372-8. 2002
    ..Furthermore, we show that Ab binding to chB6 leads to cleavage of caspase 8, caspase 3, and poly(ADP ribose) polymerase. Overall, these data support the hypothesis that chB6 is a novel death receptor on avian B cells...

Research Grants1

  1. Avian chB6 Alloantigen in Apoptosis
    PHILLIP FUNK; Fiscal Year: 2003
    ..By better understanding these issues we can begin to make hypotheses about defects that might lead to the failure to delete defective cells, potentially resulting in leukemia or autoimmune disease. ..