Research Topics
| Philip S MehlerSummaryAffiliation: Denver Health Medical Center Country: USA Publications
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Detail Information
Publications
The management of pneumothorax in patients with anorexia nervosa: A case report and review of the literatureWalter L Biffl
Department of Surgery, Denver Health Medical Center, Denver, Colorado, USA
Patient Saf Surg 4:1. 2010..We review the literature and discuss alternative approaches in this patient population...- Access and care issues in urban urgent care clinic patientsDavid R Scott
Internal Medicine, Denver Health Medical Center, 777 Bannock Street, Denver, CO 80204, USA
BMC Health Serv Res 9:222. 2009..The relevance of understanding the motivation driving this patient population is especially pertinent given recent trends towards universal healthcare and the unclear impact it may have on the demands of urgent care... 
Medical complications of bulimia nervosa and their treatmentsPhilip S Mehler
Denver Health Medical Center, Denver, Colorado, USA
Int J Eat Disord 44:95-104. 2011..To present a cogent and practical review of the medical complications and their treatment in patients with bulimia nervosa...
QT interval dispersion and resting metabolic rate in chronic anorexia nervosaMori J Krantz
Department of Internal Medicine, Denver Health and The University of Colorado Health Sciences Center, Denver, CO 80204, USA
Int J Eat Disord 37:166-70. 2005..CONCLUSIONS: AN patients with a low RMR may be at risk for increased QT dispersion. QT dispersion is a widely available and inexpensive measure, which may reflect both metabolic status and arrhythmia potential...- Torsade de pointes associated with very-high-dose methadoneMori J Krantz
Denver Health Medical Center, and the University of Colorado Health Sciences Center, Bannock Street, Mailcode 0960, Denver, CO 80204-4507, USA
Ann Intern Med 137:501-4. 2002..CONCLUSIONS: This series raises concern that very-high-dose methadone may be associated with torsade de pointes. Given the likely expansion of methadone treatment into primary care, further investigation of these findings is warranted... - Can America's urban safety net systems be a solution to unequal treatment?Sheri L Eisert
Denver Health and Hospital Authority, Denver, CO, USA
J Urban Health 85:766-78. 2008.... - High risk of osteoporosis in male patients with eating disordersPhilip S Mehler
Department of Internal Medicine, Denver Health Medical Center, Denver, Colorado 80204, USA
Int J Eat Disord 41:666-72. 2008..Osteoporosis has traditionally been considered a female problem. This study's purpose is to evaluate bone mineral density (BMD) in males with eating disorders... - "Leaning" the process of venous thromboembolism prophylaxisWalter L Biffl
Denver Health Medical Center, Denver, USA
Jt Comm J Qual Patient Saf 37:99-109. 2011..VTE risk factors were not consistently assessed, and the prescribing of prophylaxis varied widely. Lean was employed to standardize and implement risk assessment and evidence-based VTE prophylaxis for the institution... - Impact of routine infectious diseases service consultation on the evaluation, management, and outcomes of Staphylococcus aureus bacteremiaTimothy C Jenkins
Division of Infectious Diseases, Denver Health and Hospital Authority, Colorado, USA
Clin Infect Dis 46:1000-8. 2008..Staphylococcus aureus bacteremia causes considerable morbidity and mortality, and strategies to improve management and outcomes of this disease are needed... - Comprehensive coronary artery disease care in a safety-net hospital: results of Get With The Guidelines quality improvement initiativeMori J Krantz
Cardiac Risk Reduction Program, Denver Health, CO 80204, USA
J Manag Care Pharm 13:319-25. 2007..Denver Health is an example of an integrated system that encompasses both types of facilities... - Use of total parenteral nutrition in the refeeding of selected patients with severe anorexia nervosaPhilip S Mehler
Department of Internal Medicine, Denver Health Medical Center, Denver, Colorado, USA
Int J Eat Disord 40:285-7. 2007..In these case reports, we describe two patients beset with gastrointestinal comorbidities which impaired their ability to refeed with a staged oral feeding program. The use of total parenteral nutrition (TPN) facilitated their recovery... - Emergence of fluoroquinolone resistance in outpatient urinary Escherichia coli isolatesLuke Johnson
University of Denver and Department of Patient Safety and Quality, Denver Health and Hospital Authority, Denver, Colo, USA
Am J Med 121:876-84. 2008..We evaluated the effects of that switch 6 years later... - Treatment of osteopenia and osteoporosis in anorexia nervosa: a systematic review of the literaturePhilip S Mehler
Department of Internal Medicine, Denver Health Medical Center, Denver, Colorado 80204, USA
Int J Eat Disord 42:195-201. 2009..To systematically review the evidence supporting treatment of osteopenia and osteoporosis in patients with anorexia nervosa (AN)... - Complement C3 serum levels in anorexia nervosa: a potential biomarker for the severity of disease?Michael A Flierl
Department of Internal Medicine, Denver Health Medical Center, Denver, CO, USA
Ann Gen Psychiatry 10:16. 2011..The present study was designed to evaluate the role of complement C3 levels, the extent of complement activation and of complement hemolytic activity in serum, as potential new biomarkers for the severity of anorexia nervosa... - Variation in prehospital and discharge quality of care among acute myocardial infarction patients at a safety net hospitalPhilip S Mehler
Department of Patient Safety and Quality, Denver Health, Denver, CO 80204, USA
Crit Pathw Cardiol 8:127-30. 2009..A majority of AMI survivors were successfully integrated into our system postdischarge... - Skin and soft-tissue infections requiring hospitalization at an academic medical center: opportunities for antimicrobial stewardshipTimothy C Jenkins
Department of Medicine and Division of Infectious Diseases, Denver Health Medical Center, University of Colorado Denver, Denver, CO, USA
Clin Infect Dis 51:895-903. 2010..Although complicated skin and soft-tissue infections (SSTIs) are among the most common infections requiring hospitalization, their clinical spectrum, management, and outcomes have not been well described... - Wrong-site and wrong-patient procedures in the universal protocol era: analysis of a prospective database of physician self-reported occurrencesPhilip F Stahel
Department of Orthopaedic Surgery, Denver Health Medical Center, University of Colorado School of Medicine, 80204, USA
Arch Surg 145:978-84. 2010..To determine the frequency, root cause, and outcome of wrong-site and wrong-patient procedures in the era of the Universal Protocol... - Decreased antibiotic utilization after implementation of a guideline for inpatient cellulitis and cutaneous abscessTimothy C Jenkins
Department of Medicine, Denver Health Medical Center, Denver, CO 80204, USA
Arch Intern Med 171:1072-9. 2011..We hypothesized that implementation of an institutional guideline to standardize and streamline the evaluation and treatment of inpatient cellulitis and abscess would decrease antibiotic and health care resource utilization... - Osteoporosis in anorexia nervosaPhilip S Mehler
Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA
Eat Disord 19:194-202. 2011..However, successful treatments to reverse bone loss, in those with anorexia nervosa, are lacking. Early diagnosis and treatment of anorexia nervosa are paramount to prevent initial weight loss and subsequent loss of bone... - A broad and structured approach to improving patient safety and quality: lessons from Denver HealthPatricia A Gabow
Denver Health and Hospital Authority, Colorado, USA
Health Aff (Millwood) 30:612-8. 2011.... - Lack of ethnic disparities in adult immunization rates among underserved older patients in an urban public health systemAlicia Appel
Department of Internal Medicine, Denver Health, Denver, Colorado, USA
Med Care 44:1054-8. 2006..This study examines demographic differences in the rate of pneumococcal and influenza immunization in an ethnically diverse older patient population seeking care at an urban primary care clinic system... - Conventional and molecular epidemiology of trimethoprim-sulfamethoxazole resistance among urinary Escherichia coli isolatesWilliam J Burman
Department of Public Health, Denver Health and Hospital Authority, Colorado 80204, USA
Am J Med 115:358-64. 2003..We evaluated the epidemiology of trimethoprim-sulfamethoxazole-resistant E. coli in a large, public health care system in Denver, Colorado... - Treating opioid dependence. Growing implications for primary careMori J Krantz
Department of Medicine, University of Colorado Health Sciences Center, and Denver Health, Denver, CO 80204, USA
Arch Intern Med 164:277-88. 2004..Mainstreaming opioid addiction treatment has many advantages; its success will depend on resolution of ethical and delivery system issues as well as improved and expanded training of physicians in addiction medicine... - Podiatric problems are associated with worse health status in persons with severe mental illnessCynthia K Crews
Division of General Internal Medicine, University of Colorado Health Sciences Center, Denver, CO, USA
Gen Hosp Psychiatry 26:226-32. 2004..These problems are associated with worsened self-perceived health status. Addressing podiatric health may be a successful way to improve the overall health of this population... - Impact of a cardiac risk reduction program in vulnerable patients hospitalized with coronary artery diseaseMori J Krantz
Department of Medicine, Denver Health Medical Center, University of Colorado Health Sciences Center, 80204 4507, USA
Pharmacotherapy 24:768-75. 2004..To increase the use of guideline-based pharmacotherapy in vulnerable patients (ethnic minorities and the poor) with coronary artery disease (CAD) through a nurse-based quality-improvement program... - Clinical practice. Bulimia nervosaPhilip S Mehler
Internal Medicine and Community Health Services, Denver Health, Denver, CO 80204, USA
N Engl J Med 349:875-81. 2003 - Dose-related effects of methadone on QT prolongation in a series of patients with torsade de pointesMori J Krantz
Division of Cardiology, Denver Health Medical Center, University of Colorado Health Sciences Center, Denver, Colorado 80204 4507, USA
Pharmacotherapy 23:802-5. 2003..To investigate the relationship between the daily dose of the synthetic opioid methadone and the corrected QT (QTc) interval in a series of methadone-treated patients who developed torsade de pointes... - Anorexia nervosa medical issuesPhilip S Mehler
Department of Internal Medicine, Denver Health Medical Center, 660 Bannock Street, MC 1914, Denver, CO 80204, USA
J Womens Health (Larchmt) 12:331-40. 2003..In the end, a multidisciplinary team approach with input from a primary care provider who is familiar with these medical sequelae, together with psychiatric and dietary expertise, can effectuate a successful outcome... - Differential effects of antihypertensive agents on electrocardiographic voltage: results from the Appropriate Blood Pressure Control in Diabetes (ABCD) trialEdward P Havranek
Division of Cardiology, University of Colorado Health Sciences Center, Department of Medicine, Denver, USA
Am Heart J 145:993-8. 2003..Serial decline in electrocardiographic voltage in patients with increased left ventricular mass has been associated with a lower risk of cardiovascular events... - Resting tachycardia, a warning sign in anorexia nervosa: case reportMori J Krantz
Department of Medicine at Denver Health Medical Center, CO 80204, USA
BMC Cardiovasc Disord 4:10. 2004..When anorexia nervosa patients manifest tachycardia, even heart rates in the 80-90 bpm range, a supervening acute illness should be suspected... - Lack of improvement in the treatment of hyperlipidemia among patients with type 2 diabetesPhilip S Mehler
Denver Health, Denver, Colorado 80204, USA
Am J Med 114:377-82. 2003..We investigated the adequacy of treatment of hyperlipidemia in patients with type 2 diabetes, and assessed the temporal trends in adherence to published guidelines... - Bulimia: medical complicationsPhilip S Mehler
Department of Internal Medicine, Denver Health and Hospitals, 660 Bannock Street, Denver, CO 80204, USA
J Womens Health (Larchmt) 13:668-75. 2004..The American Psychiatric Association has comprehensive treatment guidelines for the management of bulimia. Primary care physicians and gynecologists need to be familiar with this disorder and its medical implications... - Osteoporosis in anorexia nervosa: prevention and treatmentPhilip S Mehler
Department of Internal Medicine, Denver Health and The University of Colorado Health Sciences Center, Denver 80204, USA
Int J Eat Disord 33:113-26. 2003..Therefore, clinicians who treat these patients must become increasingly vigilant about osteoporosis in regards to preventive, diagnostic, and treatment strategies... - A community study of language concordance in Russian patients with diabetesPhilip S Mehler
Department of Internal Medicine Denver Health, Denver, Colorado 80204, USA
Ethn Dis 14:584-8. 2004..The purpose of this study was to improve the metabolic control of Russian patients with diabetes through increased attention to language and cultural concordance between the provider and patient... - Cocaine-related torsade de pointes in a methadone maintenance patientMori J Krantz
Department of Internal Medicine, Denver Health Medical Center, Denver, CO 80204 4507, USA
J Addict Dis 24:53-60. 2005..We examine the effects of cocaine and methadone on cardiac conduction in the context of the opioid-dependent population... - Transient pulmonary infiltrates possibly induced by quinine sulfateMori J Krantz
Denver Health Medical Center, Colorado 80204, USA
Pharmacotherapy 22:775-8. 2002..No cause other than acute quinine ingestion could be identified despite thorough cardiac and infectious disease evaluations. Clinicians should be aware of a possible association between quinine sulfate and pulmonary toxicity... - Changes in insurance status and access to care in an integrated safety net healthcare systemSheri L Eisert
Department of Health Systems, Management and Policy, School of Public Health, Denver Health and Hospital Authority, Health Services Research, University of Colorado Denver Health Sciences Center, Denver, CO 80204 4507, USA
J Community Health 34:122-8. 2009..It is well documented that insurance coverage and continuity of care influence health status. Continuity of insurance coverage also has an impact on access to care for those receiving services within a safety net healthcare system... - Effects of buprenorphine on cardiac repolarization in a patient with methadone-related torsade de pointesMori J Krantz
Division of Cardiology, Denver Health Medical Center, Mail Code 0960, 777 Bannock Street, Denver, CO 80204, USA
Pharmacotherapy 25:611-4. 2005..This observation suggests that buprenorphine may be a safe alternative to oral methadone in patients with opioid addiction who develop torsade de pointes... - Bridging the quality gap in diabetic hyperlipidemia: a practice-based interventionPhilip S Mehler
Department of Internal Medicine and Cardiology Division at Denver Health, Division of Geriatrics, University of Colorado Health Sciences Center, Denver, Colo, USA
Am J Med 118:1414. 2005..Our aim was to increase the percentage of diabetic patients in whom lipid management was achieved through electronic and direct educational detailing... - QTc prolongation: methadone's efficacy-safety paradoxMori J Krantz
Denver Health Medical Center, Denver, CO 80204, USA
Lancet 368:556-7. 2006 - Liver function test abnormalities in anorexia nervosa--cause or effectVignesh Narayanan
Department of Medicine, Denver Health Medical Center, Denver, Colorado 80204, USA
Int J Eat Disord 43:378-81. 2010..Two females with severe anorexia nervosa (BMI of 10) were seen with marked abnormalities in their liver function tests before the initiation of refeeding. These paradoxically resolved with progressive refeeding and weight restoration... - Smoking abstinence after hospitalization: predictors of successThomas D MacKenzie
Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80203, USA
Prev Med 39:1087-92. 2004..Our objective was to explore the relationship between baseline characteristics of hospitalized smokers and 6-month to 2-year self-reported quit rates... - Appropriate blood pressure control in hypertensive and normotensive type 2 diabetes mellitus: a summary of the ABCD trialRobert W Schrier
Division of Renal Diseases and Hypertension, Department of Medicine, University of Colorado School of Medicine, Denver, CO 80262, USA
Nat Clin Pract Nephrol 3:428-38. 2007..Analysis of the results of 5 years of follow-up revealed a highly significant correlation of all-cause and cardiovascular mortality with left ventricular mass and severity of albuminuria... - The use of thrombelastography to determine coagulation status in severe anorexia nervosa: a case seriesJennifer L Gaudiani
Department of Medicine, Denver Health Medical Center, Denver, Colorado 80204, USA
Int J Eat Disord 43:382-5. 2010..Hospitalized medical patients have been shown to have appropriate prophylaxis for venous thromboembolic (VTE) disease in only 40% of cases... - Rapid response: a quality improvement conundrumRenata Prado
Department of Medicine, University of Colorado Denver Health Sciences Center, Denver, CO, USA
J Hosp Med 4:255-7. 2009..Therefore, we felt that prompt, mandatory bedside evaluations by the primary team would decrease untoward outcomes... - Clinical triggers: an alternative to a rapid response teamKendra Moldenhauer
Patient Safety, Quality and Regulatory Compliance, Denver Health Medical Center, Denver, CO, USA
Jt Comm J Qual Patient Saf 35:164-74. 2009..Death is the natural, albeit sad, endpoint of all lives; the overarching goal of DHMC's clinical triggers system is to prevent the premature death of a hospitalized patient and thereby improve patient safety... - Serum albumin levels may not correlate with weight status in severe anorexia nervosaVignesh Narayanan
University of Colorado Health Sciences Center and Internal Medicine, Denver Health, Denver, Colorado, USA
Eat Disord 17:322-6. 2009..Understanding that albumin levels do not correlate with the severity of anorexia nervosa is an important lesson to understand in the process of facilitating the most effective care settings for patients with severe anorexia nervosa... - Interpreting the complete blood count in anorexia nervosaBarbara S Cleary
Department of Internal Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80204, USA
Eat Disord 18:132-9. 2010..Knowledge of these potential findings and their expected outcomes may help avoid costly and potentially invasive procedures in patients with anorexia nervosa... - The paradox of normal serum albumin in anorexia nervosa: a case reportMori J Krantz
Department of Internal Medicine, Denver Health Medical Center, Denver, Colorado, USA
Int J Eat Disord 37:278-80. 2005..The presence of other potentially life-threatening conditions should be sought, as reduced serum albumin concentration is a marker of inflammation in AN...