Research Topics
| David J CieslaSummaryAffiliation: Denver Health Medical Center Country: USA Publications
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Publications
The role of the lung in postinjury multiple organ failureDavid J Ciesla
Department of Surgery, Denver Health Medical Center, Denver, Colorado 80204, USA
Surgery 138:749-57; discussion 757-8. 2005..We hypothesized that respiratory dysfunction is an early obligate event in the progression of postinjury MOF...- A 12-year prospective study of postinjury multiple organ failure: has anything changed?David J Ciesla
Department of Surgery, Denver Health Medical Center, CO 80204, USA
Arch Surg 140:432-8; discussion 438-40. 2005..The incidence and severity of postinjury multiple organ failure (MOF) has decreased over the last decade... - The academic trauma center is a model for the future trauma and acute care surgeonDavid J Ciesla
Denver Health Medical Center and the University of Colorado Health Sciences Center, Denver, Colorado, USA
J Trauma 58:657-61; discussion 661-2. 2005..Recent discussions on the future of trauma surgery stimulated us to review our experience as a possible model for the future trauma and acute care surgeon... - Multiple organ dysfunction during resuscitation is not postinjury multiple organ failureDavid J Ciesla
Denver Health Medical Center and the University of Colorado Health Sciences Center, USA
Arch Surg 139:590-4; discussion 594-5. 2004..Multiple organ dysfunction (MOD) within 48 hours of injury is a reversible physiologic response to tissue injury and resuscitation... - Carotid artery stents for blunt cerebrovascular injury: risks exceed benefitsC Clay Cothren
Department of Surgery, Denver Health Medical Center and the University of Colorado Health Sciences Center, Denver, CO 80204, USA
Arch Surg 140:480-5; discussion 485-6. 2005.... - Screening for blunt cerebrovascular injuries is cost-effectiveC Clay Cothren
Department of Surgery, Denver Health Medical Center and the University of Colorado Health Sciences Center, 777 Bannock St, Denver, CO 80204, USA
Am J Surg 190:845-9. 2005..Our hypothesis is that aggressive angiographic screening for BCVI based on a patient's injury pattern and symptoms allows for early diagnosis and treatment and is cost-effective because it prevents ischemic neurological events (INEs)... - Intubation alone does not mandate trauma surgeon presence on patient arrival to the emergency departmentDavid J Ciesla
Denver Health Medical Center and the University of Colorado Health Sciences Center, Denver, Colorado, USA
J Trauma 56:937-41; discussion 941-2. 2004..Excluding stab wounds, field or ED intubation alone rarely requires emergent surgical decision-making. Therefore, field or ED intubation alone should not mandate trauma surgeon presence on patient arrival... - Anticoagulation is the gold standard therapy for blunt carotid injuries to reduce stroke rateC Clay Cothren
Department of Surgery, Denver Health Medical Center and the University of Colorado Health Sciences Center, 80204, USA
Arch Surg 139:540-5; discussion 545-6. 2004..Aggressive screening, early angiographic diagnosis, and prompt anticoagulation for blunt carotid artery injuries (CAIs) improves neurologic outcome... - Decreased progression of postinjury lung dysfunction to the acute respiratory distress syndrome and multiple organ failureDavid J Ciesla
Denver Health Medical Center, and the University of Colorado Health Sciences Center, Denver, Colo, USA
Surgery 140:640-7; discussion 647-8. 2006..We hypothesized that the collective effects of recently implemented therapeutic strategies have resulted in decreased activation of the systemic inflammatory response relative to priming in recent years... - Emergency department resuscitative thoracotomy for nontorso injuriesForest R Sheppard
Department of Surgery, Denver Health Medical Center, Denver, CO 80204, USA
Surgery 139:574-6. 2006..CONCLUSIONS: Resuscitative EDT with aortic cross-clamping is a potential adjunct in the acute resuscitation of NTI involving penetrating neck or extremity vascular injuries... - Post-hemorrhagic shock mesenteric lymph activates human pulmonary microvascular endothelium for in vitro neutrophil-mediated injury: the role of intercellular adhesion molecule-1Ricardo J Gonzalez
Department of Surgery, Denver Health Medical Center and University of Colorado, 80204, USA
J Trauma 54:219-23. 2003..These findings further substantiate the key mechanistic role of mesenteric lymph in hemorrhagic shock-induced acute lung injury and suggest that ICAM-1 expression is pivotal in the two-event model of multiple organ failure... - Postinjury abdominal compartment syndrome does not preclude early enteral feeding after definitive closureC Clay Cothren
Department of Surgery, Denver Health Medical Center, and the University of Colorado Health Sciences Center, 777 Bannock St, MC 0206, Denver, CO 80204, USA
Am J Surg 188:653-8. 2004..The purpose of this study was to determine if enteral nutrition was precluded by the intra-abdominal hypertension and bowel edema of the ACS... - Has the trauma surgeon become house staff for the surgical subspecialist?David J Ciesla
Department of Surgery, Washington Hospital Center, 110 Irving St NW, Suite 4B 39, Washington, DC 20005, USA
Am J Surg 192:732-7. 2006..The role of the trauma surgeon is perceived to be mostly supportive of other procedure-oriented specialties. We designed this study to characterize the surgical and nonsurgical responsibilities of the contemporary trauma surgeon... - Obesity increases risk of organ failure after severe traumaDavid J Ciesla
Department of Surgery, Washington Hospital Center, 110 Irving Street NW, Washington, DC 20005, USA
J Am Coll Surg 203:539-45. 2006..The purpose of this study was to determine the relationship between obesity and postinjury multiple organ failure (MOF)... - Can we afford to do laparoscopic appendectomy in an academic hospital?C Clay Cothren
The Department of Surgery, Denver Health Medical Center and the University of Colorado Health Sciences Center, 777 Bannock Street, MC 0206, Denver, CO 80204, USA
Am J Surg 190:950-4. 2005..The purpose of this study was to determine if laparoscopic appendectomy is more expensive than open appendectomy... - Cervical spine fracture patterns predictive of blunt vertebral artery injuryC Clay Cothren
Department of Surgery, Denver Health Medical Center and University of Colorado Health Sciences Center, 777 Bannock Street, Denver, CO 80204, USA
J Trauma 55:811-3. 2003..Because of the proximity of the cervical spine and vertebral arteries, we queried whether all patients with cervical spine fractures required arteriography to rule out VAI... - Validation of postinjury multiple organ failure scoresAngela Sauaia
Department of Medicine, Division of Health Care Policy and Research, University of Colorado, Denver, Colorado, USA
Shock 31:438-47. 2009..Basic concepts of each score can probably be combined to produce an improved MOF score... - Radiographic characteristics of postinjury splenic autotransplantation: avoiding a diagnostic dilemmaC Clay Cothren
Department of Surgery, Denver Health Medical Center and the University of Colorado Health Sciences Center, Denver, Colorado, USA
J Trauma 57:537-41. 2004..The purpose of this study was to determine whether there is a characteristic radiographic appearance of splenic implants, whether this appearance changes with time, and whether implants can be differentiated from abdominal abscesses... - Is emergency department resuscitative thoracotomy futile care for the critically injured patient requiring prehospital cardiopulmonary resuscitation?Danny W Powell
Department of Surgery, Denver Health Medical Center, and the University of Colorado Health Sciences Center, Denver, CO 80204 4507, USA
J Am Coll Surg 199:211-5. 2004..Consequently, we questioned whether resuscitative thoracotomy is warranted in the critically injured patient who fails to respond to prehospital CPR... - Clinically relevant hypertonicity prevents stored blood- and lipid-mediated delayed neutrophil apoptosis independent of p38 MAPK or caspase-3 activationWalter L Biffl
Department of Surgery, Rhode Island Hospital/Brown Medical School, Providence, RI, USA
Surgery 134:86-91. 2003..HTS may activate caspase-3, but alternative signaling pathways appear to be involved in modulating the effects of lipids on PMN apoptosis... - Secondary overtriage: a consequence of an immature trauma systemDavid J Ciesla
Department of Surgery, Washington Hospital Center, Washington, DC 20005, USA
J Am Coll Surg 206:131-7. 2008..The purpose of this study was to determine the incidence of secondary overtriage in a region without a formal trauma system... - Trauma patients: you can get them in, but you can't get them outDavid J Ciesla
Department of Surgery, Washington Hospital Center, Washington, DC, USA
Am J Surg 195:78-83. 2008..The majority of inpatient trauma care resources are consumed by a small proportion of severely injured patients... - Implementation of an acute care surgery service at an academic trauma centerDavid J Ciesla
Department of Surgery, University of South Florida College of Medicine and Tampa General Hospital, Tampa, FL, USA
Am J Surg 202:779-85; discussion 785-6. 2011..The establishment of acute care surgery is rapidly becoming a solution to meet emergency surgical needs. Challenges include competition for emergency surgery opportunities and the ability to economically sustain a practice... - Image of the month: SchwannomaC Clay Cothren
Department of Surgery, Denver Health Medical Center, Denver, CO 80204, USA
Arch Surg 141:941-2. 2006 - Geographic distribution of severely injured patients: implications for trauma system developmentDavid J Ciesla
Department of Surgery, University of South Florida College of Medicine, Tampa, FL 33606, USA
J Trauma Acute Care Surg 73:618-24. 2012..The purpose of this study was to define the regions served by Florida's designated trauma centers and define the geographic distribution of severely injured patients who do not access the state's trauma system... - Hyperosmolarity abrogates neutrophil cytotoxicity provoked by post-shock mesenteric lymphRicardo J Gonzalez
Denver Health Medical Center, Department of Surgery, Colorado 80204, USA
Shock 18:29-32. 2002..These studies suggest inhibition of PMN signal transduction is a mechanism whereby HTS resuscitation abrogates acute lung injury... - Transverse sternal approach for thymectomyDavid J Ciesla
Department of Surgery, Denver Health Medical Center, University of Colorado Health Sciences Center, 777 Bannock Street, Denver, CO 80204, USA
Surgery 133:226-7. 2003 - The acute care surgeon and emergency specialty proceduresDavid J Ciesla
J Am Coll Surg 205:187-9. 2007 - Trauma systems and access to emergency medical careDavid J Ciesla
Washington Hospital Center, Washington, DC, USA
J Trauma 62:S51. 2007