Carlton C Barnett

Summary

Affiliation: Denver Health Medical Center
Country: USA

Publications

  1. doi request reprint Primary repair of civilian colon injuries is safe in the damage control scenario
    Jeffry L Kashuk
    Department of Surgery, Denver Health Medical Center, University of Colorado Denver and Health Sciences Center, Denver, CO 80204, USA
    Surgery 146:663-8; discussion 668-70. 2009
  2. pmc Reconstruction of an emergency thoracotomy wound with free rectus abdominis flap: Anatomic and radiologic basis for the surgical technique
    Kaitlyn Gilman
    Department of Plastic and Reconstructive Surgery, Denver Health Medical Center, University of Colorado Health Sciences Center, 777 Bannock Street, Denver, 80204 Colorado USA
    World J Emerg Surg 5:12. 2010
  3. pmc Intravenous delivery of the plasma fraction of stored packed erythrocytes promotes pancreatic cancer growth in immunocompetent mice
    Carlton C Barnett
    Department of Surgery, University of Colorado at Denver, Denver Health Medical Center, Denver, Colorado 80204 0206, USA
    Cancer 116:3862-74. 2010
  4. doi request reprint Perioperative blood transfusions promote pancreas cancer progression
    Douglas Benson
    Department of Surgery, Denver Health Medical Center, University of Colorado at Denver, Colorado 80204 0206, USA
    J Surg Res 166:275-9. 2011
  5. doi request reprint Hemicorporectomy: back to front
    Carlton C Barnett
    Department of Surgery, Denver Health Medical Center, University of Colorado, 777 Bannock St, Denver, CO 80204, USA
    Am J Surg 196:1000-2. 2008
  6. doi request reprint Early death and late morbidity after blood transfusion of injured children: a pilot study
    Fredric M Pieracci
    Department of Surgery, Denver Health Medical Center, Denver, CO 80206, USA
    J Pediatr Surg 47:1587-91. 2012
  7. pmc Accumulation of pro-cancer cytokines in the plasma fraction of stored packed red cells
    Douglas D Benson
    Denver Health Medical Center, 777 Bannock St, Denver, CO 80204 0206, USA
    J Gastrointest Surg 16:460-8. 2012
  8. doi request reprint Activation state of stromal inflammatory cells in murine metastatic pancreatic adenocarcinoma
    Douglas D Benson
    Denver Health Medical Center, Denver, CO 80204 0206, USA
    Am J Physiol Regul Integr Comp Physiol 302:R1067-75. 2012
  9. doi request reprint Tumor-derived intercellular adhesion molecule-1 mediates tumor-associated leukocyte infiltration in orthotopic pancreatic xenografts
    Christina L Roland
    Division of Surgical Oncology, Department of Surgery, Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical School, Dallas, TX, USA
    Exp Biol Med (Maywood) 235:263-70. 2010
  10. pmc Hemoglobin-based oxygen carrier mitigates transfusion-mediated pancreas cancer progression
    Karen K Lo
    Department of Surgery, Denver Health Medical Center, University of Colorado Denver, Denver, CO, USA
    Ann Surg Oncol 20:2073-7. 2013

Collaborators

Detail Information

Publications32

  1. doi request reprint Primary repair of civilian colon injuries is safe in the damage control scenario
    Jeffry L Kashuk
    Department of Surgery, Denver Health Medical Center, University of Colorado Denver and Health Sciences Center, Denver, CO 80204, USA
    Surgery 146:663-8; discussion 668-70. 2009
    ..We hypothesized that, even in the high-risk DL group, primary repair could be safely used after patient stabilization and that the open abdomen would facilitate the safety of this procedure...
  2. pmc Reconstruction of an emergency thoracotomy wound with free rectus abdominis flap: Anatomic and radiologic basis for the surgical technique
    Kaitlyn Gilman
    Department of Plastic and Reconstructive Surgery, Denver Health Medical Center, University of Colorado Health Sciences Center, 777 Bannock Street, Denver, 80204 Colorado USA
    World J Emerg Surg 5:12. 2010
    ..The deep inferior epigastric vessels of the flap were anastomosed to the right internal mammary vessels proximal to their transection level in the third-forth intercostal space. The flap healed with no further wound complications...
  3. pmc Intravenous delivery of the plasma fraction of stored packed erythrocytes promotes pancreatic cancer growth in immunocompetent mice
    Carlton C Barnett
    Department of Surgery, University of Colorado at Denver, Denver Health Medical Center, Denver, Colorado 80204 0206, USA
    Cancer 116:3862-74. 2010
    ....
  4. doi request reprint Perioperative blood transfusions promote pancreas cancer progression
    Douglas Benson
    Department of Surgery, Denver Health Medical Center, University of Colorado at Denver, Colorado 80204 0206, USA
    J Surg Res 166:275-9. 2011
    ..Based on these findings, as well as the continued need for blood transfusion, alternate strategies in transfusion management are warranted...
  5. doi request reprint Hemicorporectomy: back to front
    Carlton C Barnett
    Department of Surgery, Denver Health Medical Center, University of Colorado, 777 Bannock St, Denver, CO 80204, USA
    Am J Surg 196:1000-2. 2008
    ..In addition, this approach greatly improves exposure of the pelvic vessels, allowing for a technically less challenging and safer procedure...
  6. doi request reprint Early death and late morbidity after blood transfusion of injured children: a pilot study
    Fredric M Pieracci
    Department of Surgery, Denver Health Medical Center, Denver, CO 80206, USA
    J Pediatr Surg 47:1587-91. 2012
    ..The adverse immunomodulatory effects of blood transfusion are implicated in subsequent morbidity. We hypothesized that injured children requiring pRBC transfusion demonstrate patterns in outcome similar to those observed in adults...
  7. pmc Accumulation of pro-cancer cytokines in the plasma fraction of stored packed red cells
    Douglas D Benson
    Denver Health Medical Center, 777 Bannock St, Denver, CO 80204 0206, USA
    J Gastrointest Surg 16:460-8. 2012
    ..We analyzed the plasma fraction of stored pRBCs for pro-cancer cytokines and evaluated the affect of both storage time and leukocyte reduction on these mediators...
  8. doi request reprint Activation state of stromal inflammatory cells in murine metastatic pancreatic adenocarcinoma
    Douglas D Benson
    Denver Health Medical Center, Denver, CO 80204 0206, USA
    Am J Physiol Regul Integr Comp Physiol 302:R1067-75. 2012
    ..TANs are localized at the invasive front of the metastasis, where they colocalize with MMP-9. Improved understanding of these interactions may lead to targeted therapies for pancreas adenocarcinoma...
  9. doi request reprint Tumor-derived intercellular adhesion molecule-1 mediates tumor-associated leukocyte infiltration in orthotopic pancreatic xenografts
    Christina L Roland
    Division of Surgical Oncology, Department of Surgery, Hamon Center for Therapeutic Oncology Research, The University of Texas Southwestern Medical School, Dallas, TX, USA
    Exp Biol Med (Maywood) 235:263-70. 2010
    ..These results suggest that tumor-derived ICAM-1 is a sufficient ligand for tumor-associated PMNs and may play a role in subsequent tumor growth and metastasis...
  10. pmc Hemoglobin-based oxygen carrier mitigates transfusion-mediated pancreas cancer progression
    Karen K Lo
    Department of Surgery, Denver Health Medical Center, University of Colorado Denver, Denver, CO, USA
    Ann Surg Oncol 20:2073-7. 2013
    ..We hypothesize these untoward effects will be mitigated by use of a hemoglobin-based oxygen carrier (HBOC)...
  11. pmc Effect of damage control surgery on major abdominal vascular trauma
    Talia A Sorrentino
    University of Colorado Denver, Denver, Colorado, USA
    J Surg Res 177:320-5. 2012
    ..Damage control surgery was subsequently introduced to address this "lethal triad." The purpose of the present study was to evaluate the outcomes from our most recent 6-year experience compared with a cohort from 30 years ago...
  12. doi request reprint Blunt cerebrovascular injuries in the child
    Teresa S Jones
    Department of Surgery, Denver Health Medical Center, Denver, CO, USA
    Am J Surg 204:7-10. 2012
    ..The purpose of this study was to describe the incidence, injury patterns, and stroke rates of pediatric patients sustaining BCVIs...
  13. doi request reprint A negative urinalysis rules out catheter-associated urinary tract infection in trauma patients in the intensive care unit
    Robert T Stovall
    Department of Surgery, Denver Health Medical Center and the University of Colorado School of Medicine, Denver, CO 80206, USA
    J Am Coll Surg 217:162-6. 2013
    ..Whether the urinalysis (UA) is an adequate test for a urinary source of fever in the ICU trauma patient has not been demonstrated. We hypothesized that the UA is a valuable screen for UTI in the febrile, critically ill trauma patient...
  14. doi request reprint Acute appendicitis: a disease severity score for the acute care surgeon
    Geoffrey C Garst
    Department of Surgery, Denver Health Medical Center, University of Colorado Denver, Denver, Colorado, USA
    J Trauma Acute Care Surg 74:32-6. 2013
    ..Analogous to organ injury scales developed for trauma, a scoring system is needed for acute care surgery. The purpose of this study was to develop a disease severity score (DSS) for acute appendicitis, the most common surgical emergency...
  15. pmc The plasma fraction of stored erythrocytes augments pancreatic cancer metastasis in male versus female mice
    Peter K Moore
    School of Medicine, University of Colorado at Denver, Denver, Colorado, USA
    J Surg Res 164:23-7. 2010
    ..We therefore hypothesize that male mice with pancreatic cancer will have greater tumor progression than female mice in response to transfusion...
  16. doi request reprint Vascular endothelial growth factor receptor 2 mediates macrophage infiltration into orthotopic pancreatic tumors in mice
    Sean P Dineen
    Division of Surgical Oncology, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390 8593, USA
    Cancer Res 68:4340-6. 2008
    ..Our results show an underappreciated mechanism of action that may directly contribute to the antitumor activity of angiogenesis inhibitors that block the VEGFR2 pathway...
  17. doi request reprint The acellular fraction of stored platelets promotes tumor cell invasion
    Sean P Dineen
    Division of Surgical Oncology, Department of Surgery, University of Texas Southwestern Medical School, Dallas, Texas 75390, USA
    J Surg Res 153:132-7. 2009
    ..Platelets are ubiquitously present in blood transfusions and contain numerous growth factors that may contribute to tumor growth. We hypothesized that such growth factors released during routine platelet storage promote cancer invasion...
  18. doi request reprint The age of transfused blood predicts hematocrit response among critically ill surgical patients
    Fredric M Pieracci
    Department of Surgery, Denver Health Medical Center University of Colorado Health Science Center, 777 Bannock St, MC0206, Denver, CO 80206, USA
    Am J Surg 204:269-73. 2012
    ..In vitro data suggest that erythrocytes undergo storage time-dependent degradation, eventuating in hemolysis. We hypothesize that transfusion of old blood, as compared with newer blood, results in a smaller increment in hematocrit...
  19. pmc Gender-specific transfusion affects tumor-associated neutrophil: macrophage ratios in murine pancreatic adenocarcinoma
    Douglas D Benson
    Denver Health Medical Center, 777 Bannock Street, Denver, CO 80204 0206, USA
    J Gastrointest Surg 14:1560-5. 2010
    ..To test this hypothesis, we examined tumor-associated neutrophils and macrophage ratios in male and female mice with pancreatic cancer receiving blood transfusion from male or female donors...
  20. doi request reprint Blunt cerebrovascular injuries: redefining screening criteria in the era of noninvasive diagnosis
    Clay Cothren Burlew
    Department of Surgery, Denver Health Medical Center and the University of Colorado School of Medicine, Denver, CO 80204, USA
    J Trauma Acute Care Surg 72:330-5; discussion 336-7, quiz 539. 2012
    ..The purpose of this study was to identify injury patterns of patients with BCVI that are not currently recommended screening criteria...
  21. doi request reprint One hundred percent fascial approximation can be achieved in the postinjury open abdomen with a sequential closure protocol
    Clay Cothren Burlew
    Department of Surgery, Denver Health Medical Center and the University of Colorado, Denver, Colorado, USA
    J Trauma Acute Care Surg 72:235-41. 2012
    ..We hypothesized that a sequential closure technique performed by a systematic protocol would achieve a higher rate of primary fascial closure than other described techniques...
  22. pmc Sexual dimorphism in hematocrit response following red blood cell transfusion of critically ill surgical patients
    Fredric M Pieracci
    Department of Surgery, Denver Health Medical Center, University of Colorado Health Science Center, 777 Bannock Street MC0206, Denver, CO 80206, USA
    ISRN Hematol 2012:298345. 2012
    ..This association does not appear related to either demographic or anthropomorphic factors, raising the possibility of gender-related differences in recipient immune response to transfusion...
  23. doi request reprint A cost-minimization analysis of phenytoin versus levetiracetam for early seizure pharmacoprophylaxis after traumatic brain injury
    Fredric M Pieracci
    Division of Trauma and Acute Care Surgery, Denver Health Medical Center, Denver, Colorado 80206, USA
    J Trauma Acute Care Surg 72:276-81. 2012
    ..The purpose of this study was to conduct a cost-minimization analysis, from the perspective of both the acute care institution (cost) and patient (charges), comparing these two strategies...
  24. ncbi request reprint Increased expression of Cyr61 (CCN1) identified in peritoneal metastases from human pancreatic cancer
    Shane E Holloway
    Division of Surgical Oncology, Department of Surgery, Hamon Center for Therapeutic Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390 8593, USA
    J Am Coll Surg 200:371-7. 2005
    ..We hypothesized that comparison of ECM-associated gene expression in primary and metastatic pancreatic tumors would identify ECM proteins associated with pancreatic metastasis...
  25. doi request reprint Mechanism of injury alone is not justified as the sole indication for computed tomographic imaging in blunt pediatric trauma
    Hunter B Moore
    From the Department of Surgery, Denver Health Medical Center, University of Colorado, Denver School of Medicine, Denver, Colorado
    J Trauma Acute Care Surg 75:995-1001. 2013
    ..We hypothesized that CT imaging performed for mechanism of injury alone is unnecessary and that serious or life-threatening injury is rarely identified...
  26. doi request reprint Surgeons provide definitive care to patients with gallstone pancreatitis
    Sarah E Judkins
    Department of Surgery, Denver Health Medical Center, The University of Colorado Denver School of Medicine, Denver, CO 80204, USA
    Am J Surg 202:673-7; discussion 677-8. 2011
    ..There are wide variations in the use of diagnostic testing and same-stay cholecystectomy. We hypothesize that a general surgery service (SURG) will deliver more efficient, definitive care for patients with GP...
  27. doi request reprint Preperitoneal pelvic packing/external fixation with secondary angioembolization: optimal care for life-threatening hemorrhage from unstable pelvic fractures
    Clay Cothren Burlew
    Department of Surgery, Denver Health Medical Center and the University of Colorado Denver, Denver, CO 80204, USA
    J Am Coll Surg 212:628-35; discussion 635-7. 2011
    ..We hypothesized that PPP/EF arrests hemorrhage rapidly, facilitates emergent operative procedures, and ensures efficient use of angioembolization (AE)...
  28. doi request reprint Refractory postinjury thrombocytopenia is associated with multiple organ failure and adverse outcomes
    Trevor L Nydam
    Department of Surgery, University of Colorado Health Science Center and School of Medicine, Aurora, Colorado 80045, USA
    J Trauma 70:401-6; discussion 406-7. 2011
    ..In addition, recent studies suggest that platelets play a critical role in postinjury hyperinflammation. Therefore, we hypothesized that postinjury thrombocytopenia is a marker for progression to MOF...
  29. doi request reprint One thousand bedside percutaneous tracheostomies in the surgical intensive care unit: time to change the gold standard
    Lucy Z Kornblith
    Department of Surgery, Denver Health Medical Center and theUniversity of Colorado, Denver, CO, USA
    J Am Coll Surg 212:163-70. 2011
    ..Because this has been our preferred technique in the surgical ICU for more than 20 years, we reviewed our experience to ascertain its safety. We hypothesize that BPT has acceptably minimal morbidity, even in high-risk patients...
  30. doi request reprint Effect of educational debt on career and quality of life among academic surgeons
    Melina R Kibbe
    Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Ann Surg 249:342-8. 2009
    ..The purpose of this study was to assess indebtedness among academic surgeons and its repercussions on personal finances, quality of life, and career choices...
  31. ncbi request reprint ICAM-1 expression determines malignant potential of cancer
    Christina L Roland
    Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Tex, USA
    Surgery 141:705-7. 2007
    ..Consequently, tumor cell ICAM-1 expression dictates metastatic potential and metastatic potential determines cancer lethality...
  32. doi request reprint Post-discharge venous thromboembolism after cancer surgery: extending the case for extended prophylaxis
    Ryan P Merkow
    Department of Surgery, Jesse Brown VAMC, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Ann Surg 254:131-7. 2011
    ..To (1) define the frequency of overall and postdischarge venous thromboembolism (VTE) after cancer surgery, (2) identify VTE risk for individual cancer operations, and (3) assess mortality rates in patients who experienced a VTE...