M A Deeg

Summary

Country: USA

Publications

  1. ncbi Regulation of glycosylphosphatidylinositol-specific phospholipase D secretion from beta TC3 cells
    M A Deeg
    Department of Medicine, Indiana University School of Medicine, Indianapolis 46202, USA
    Endocrinology 138:819-26. 1997
  2. ncbi Glucose and insulin regulate glycosylphosphatidylinositol-specific phospholipase D expression in islet beta cells
    R F Bowen
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202-2883, USA
    Metabolism 50:1489-92. 2001
  3. ncbi Midportion antibodies stimulate glycosylphosphatidylinositol-specific phospholipase D activity
    M A Deeg
    Department of Medicine, Indiana University School of Medicine and The Richard L Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana 46202 2284, USA
    Arch Biochem Biophys 370:278-84. 1999
  4. ncbi Increased expression of GPI-specific phospholipase D in mouse models of type 1 diabetes
    M A Deeg
    Department of Medicine, Indiana University School of Medicine and The Richard L Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana 46202, USA
    Am J Physiol Endocrinol Metab 281:E147-54. 2001

Collaborators

Detail Information

Publications4

  1. ncbi Regulation of glycosylphosphatidylinositol-specific phospholipase D secretion from beta TC3 cells
    M A Deeg
    Department of Medicine, Indiana University School of Medicine, Indianapolis 46202, USA
    Endocrinology 138:819-26. 1997
    ..These results demonstrate that beta TC3 cells secrete GPI-PLD in response to insulin secretagogues and suggest that GPI-PLD may be secreted via the regulated pathway in these cells...
  2. ncbi Glucose and insulin regulate glycosylphosphatidylinositol-specific phospholipase D expression in islet beta cells
    R F Bowen
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202-2883, USA
    Metabolism 50:1489-92. 2001
    ..These regulators may also account for the increased expression of GPI-PLD mRNA in islets from ob/ob mice, a model of insulin resistance and islet hyperactivity...
  3. ncbi Midportion antibodies stimulate glycosylphosphatidylinositol-specific phospholipase D activity
    M A Deeg
    Department of Medicine, Indiana University School of Medicine and The Richard L Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana 46202 2284, USA
    Arch Biochem Biophys 370:278-84. 1999
    ..Consistent with this is the observation that both manipulations decreased the affinity of GPI-PLD for mixed micelle substrates. These results indicate that the midportion region of GPI-PLD is important in regulating enzymatic activity...
  4. ncbi Increased expression of GPI-specific phospholipase D in mouse models of type 1 diabetes
    M A Deeg
    Department of Medicine, Indiana University School of Medicine and The Richard L Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana 46202, USA
    Am J Physiol Endocrinol Metab 281:E147-54. 2001
    ..Our data demonstrate that serum GPI-PLD levels are altered in the diabetic state and are consistent with liver as a contributor to circulating GPI-PLD...