Kenneth A Kobak
Affiliation: Dean Health System
- St John's wort versus placebo in obsessive-compulsive disorder: results from a double-blind studyKenneth A Kobak
Dean Foundation for Health Research and Education, Middleton, Wisconsin 53562, USA
Int Clin Psychopharmacol 20:299-304. 2005..9%) and placebo (16.7%) (P=0.905). Only one patient from each group discontinued due to adverse events [sinus infection (St John's wort); confusion (placebo)]. The results fail to support the efficacy of St John's wort for OCD...
- Prevalence and burden of illness of migraine in managed care patientsKenneth A Kobak
Dean Foundation for Health Education and Research, 2711 Allen Blvd, Middleton, WI 53562, USA
J Manag Care Pharm 11:124-36. 2005..maintenance organization (HMO) population, using a 2-stage screening process and neurologist exam, and to examine the burden of illness associated with both previously diagnosed and previously undiagnosed migraine in this population..
- St. John's wort versus placebo in social phobia: results from a placebo-controlled pilot studyKenneth A Kobak
Dean Foundation for Health Research and Education, Middleton, WI, USA
J Clin Psychopharmacol 25:51-8. 2005..Results of the study fail to provide evidence for the efficacy of SJW in social phobia. The impact of methodologic improvements on signal detection, while suggestive of improvement, remains to be established...
- Fluoxetine in social phobia: a double-blind, placebo-controlled pilot studyKenneth A Kobak
Dean Foundation for Health, Research and Education, Middleton, Wisconsin, USA
J Clin Psychopharmacol 22:257-62. 2002..Fluoxetine failed to separate from placebo in this trial. It is unknown whether a larger dose for longer duration would have yielded separation from placebo. A higher than usual placebo response rate was found...
- Sources of unreliability in depression ratingsKenneth A Kobak
MedAvante Research Institute, Madison, WI, USA
J Clin Psychopharmacol 29:82-5. 2009..We videotaped and transcribed 30 pairs of interviews to examine the most common sources of rater unreliability...
- Antidepressant medication management and Health Plan Employer Data Information Set (HEDIS) criteria: reasons for nonadherenceKenneth A Kobak
Dean Foundation for Health, Research and Education, 2711 Allen Blvd, Middleton, WI 53562, USA
J Clin Psychiatry 63:727-32. 2002..We examined the reasons for this failure through a systematic chart review...
- PANSS rater training using Internet and videoconference: results from a pilot studyKenneth A Kobak
MedAvante, Inc, 7601 Ganser Way, Madison, WI 53719, USA
Schizophr Res 92:63-7. 2007..The use of these technologies allows for training to be more effectively delivered to diverse sites in multi-center trials, and for evaluation of raters' applied clinical skills, an area that has previously been overlooked...
- A novel approach to rater training and certification in multinational trialsElizabeth Jeglic
MedAvante Research Institute, Ganser Way, Madison, Wisconsin 53719, USA
Int Clin Psychopharmacol 22:187-91. 2007..25 to 11.31, P=0.003. These results support the efficacy of this applied training model in improving raters' applied clinical skills in multinational trials...
- Cost-effectiveness of computer-aided behaviour therapy for obsessive-compulsive disorderPaul McCrone
Psychother Psychosom 76:249-50. 2007
- Are the effects of rater training sustainable? Results from a multicenter clinical trialKenneth A Kobak
J Clin Psychopharmacol 27:534-5. 2007
- Development and reliability of a structured interview guide for the Montgomery Asberg Depression Rating Scale (SIGMA)Janet B W Williams
Biometrics Research Unit, Columbia University, New York, New York, USA
Br J Psychiatry 192:52-8. 2008..Structured and semi-structured interview guides have been found to improve reliability with other scales...
- The GRID-HAMD: standardization of the Hamilton Depression Rating ScaleJanet B W Williams
Columbia University, New York, NY, USA
Int Clin Psychopharmacol 23:120-9. 2008..Overall, these data suggest that the GRID-HAMD is an improvement over the original Guy version as well as the SIGH-D in its incorporation of innovative features and preservation of high reliability and validity...
- Rating the raters: assessing the quality of Hamilton rating scale for depression clinical interviews in two industry-sponsored clinical drug trialsNina Engelhardt
MedAvante, Inc MedAvante, Ewing, NJ, USA
J Clin Psychopharmacol 26:71-4. 2006..We evaluated the quality of Hamilton Rating Scale for Depression (HAM-D) clinical interviews performed at baseline in 2 similar multicenter, randomized, placebo-controlled depression trials sponsored by 2 pharmaceutical companies...
- Why the Hamilton Depression Rating Scale enduresPer Bech
Am J Psychiatry 162:2396; author reply 2397-8. 2005
- A new approach to rater training and certification in a multicenter clinical trialKenneth A Kobak
MedAvante Inc, 7601 Ganser Way, Madison, WI 53719, USA
J Clin Psychopharmacol 25:407-12. 2005..00 to 11.00, P = 0.033. Three raters failed all 3 attempts and were excluded from the study. Results support the efficacy of the approach in improving both conceptual knowledge and applied interviewing skill...
- Interview quality and signal detection in clinical trialsKenneth A Kobak
Am J Psychiatry 162:628. 2005
- A comparison of face-to-face and videoconference administration of the Hamilton Depression Rating ScaleKenneth A Kobak
Research Training Associates and MedAvante, Madison, Wisconsin 53719, USA
J Telemed Telecare 10:231-5. 2004..The study shows the psychometric equivalence of remote and face-to-face HAMD administration...
- Development of a standardized training program for the Hamilton Depression Scale using internet-based technologies: results from a pilot studyKenneth A Kobak
Research Training Associates, Madison, WI 53719, USA
J Psychiatr Res 37:509-15. 2003..97, P<0.0001. Results support the feasibility of this methodology for improving rater training. An NIMH funded study is currently underway examining this methodology in a multi-site trial...
- St. John's wort in generalized anxiety disorder: three more case reportsKenneth A Kobak
J Clin Psychopharmacol 23:531-2. 2003
- Obsessive-compulsive symptom dimensions as predictors of compliance with and response to behaviour therapy: results from a controlled trialDavid Mataix-Cols
Department of Psychiatry, Imperial College School of Medicine, London, UK
Psychother Psychosom 71:255-62. 2002..Existing treatments need to be refined and/or new treatments developed to improve these patients' adherence and response to treatment...
- Behavior therapy for obsessive-compulsive disorder guided by a computer or by a clinician compared with relaxation as a controlJohn H Greist
Healthcare Technology Systems, and the University of Wisconsin, Madison, 53717, USA
J Clin Psychiatry 63:138-45. 2002..This study compared the value of computer-guided behavior therapy value with that of clinician-guided behavior therapy and systematic relaxation as a control treatment...