Research Topics
| L L DavisSummaryCountry: USA Publications
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Detail Information
Publications
Effect of concurrent substance use disorder on the effectiveness of single and combination antidepressant medications for the treatment of major depression: an exploratory analysis of a single-blind randomized trialLori L Davis
VA Medical Center, Tuscaloosa, Alabama 35404, United States
Depress Anxiety 29:111-22. 2012..These patients are often excluded from clinical trials, resulting in a significant knowledge gap regarding optimal pharmacotherapy for the treatment of MDD with concurrent SUD...
A placebo-controlled trial of guanfacine for the treatment of posttraumatic stress disorder in veteransLori L Davis
University of Alabama School of Medicine, Birmingham, AL, USA
Psychopharmacol Bull 41:8-18. 2008..This study tests the ability of the a(2) adrenergic agonist, guanfacine, to reduce the symptoms of PTSD...
Substance use disorder comorbidity in major depressive disorder: an exploratory analysis of the Sequenced Treatment Alternatives to Relieve Depression cohortLori L Davis
VA Medical Center, Tuscaloosa, AL 35404, USA
Compr Psychiatry 46:81-9. 2005..In conclusion, gender, marital status, age of onset of major depression, functional impairment, and suicide risk factors differ in depressed patients with concurrent SUD symptoms compared to those without SUD comorbidity...
Divalproex sodium in the treatment of adults with bipolar disorderLori L Davis
University of Alabama at Birmingham, Birmingham, AL, USA
Expert Rev Neurother 4:349-62. 2004..The use of divalproex in the treatment of bipolar and other related psychiatric disorders is reviewed...
A placebo-controlled study of nefazodone for the treatment of chronic posttraumatic stress disorder: a preliminary studyLori L Davis
VA Medical Center 151, 3701 Loop Road East, Tuscaloosa, AL 35404, USA
J Clin Psychopharmacol 24:291-7. 2004..06). This pilot study supports the efficacy of nefazodone for the treatment of PTSD. However, larger placebo-controlled studies in more diverse patient population are warranted...
Pharmacotherapy for post-traumatic stress disorder: a comprehensive reviewL L Davis
Veterans Affairs Medical Center, 3701 Loop Road East, Tuscaloosa, Alabama 35404, USA
Expert Opin Pharmacother 2:1583-95. 2001..Also, there are virtually no data on pharmacotherapy for acute stress reaction or for PTSD in children. Future directions for research may focus on combination treatment in the more treatment-resistant patient populations...
Substance use disorder comorbidity in major depressive disorder: a confirmatory analysis of the STAR*D cohortLori L Davis
VA Medical Center, Tuscaloosa, AL 35404, USA
Am J Addict 15:278-85. 2006..048 to <0.0001). They were also less likely to be Hispanic and endorse general medical comorbidities (p = 0.006 and 0.002, respectively)...
Divalproex in the treatment of bipolar depression: a placebo-controlled studyLori L Davis
Veteran s Affairs Medical Center 151, 3701 Loop Road East, Tuscaloosa, AL 35404, USA
J Affect Disord 85:259-66. 2005..Thus, the potential antidepressant efficacy of mood stabilizers, such as divalproex, which is an effective treatment for the manic phase of bipolar disorder, is of considerable interest...
Nefazodone treatment for chronic posttraumatic stress disorder: an open trialL L Davis
Department of Veterans Affairs Medical Center at Tuscaloosa, Alabama 35404, USA
J Clin Psychopharmacol 20:159-64. 2000..In summary, nefazodone treatment improved the symptoms of PTSD, including the core symptoms. Placebo-controlled studies should be undertaken to further elucidate the efficacy of nefazodone in the treatment of PTSD...
Comprehensive review of the psychiatric uses of valproateL L Davis
Veteran s Affairs Medical Center, Tuscaloosa, Alabama 35404, USA
J Clin Psychopharmacol 20:1S-17S. 2000..The authors conclude with a brief summary of its mechanism of action and therapeutic spectrum...
Growth hormone response to the GABAB agonist baclofen in major depressive disorderL L Davis
Veterans Affairs Medical Center, Dallas, TX 75216, USA
Psychoneuroendocrinology 22:129-40. 1997..Age significantly correlated with GH response, with older subjects having lower GH response to baclofen. These data do not suggest that a blunted GH response to baclofen. represents a specific neuroendocrine feature of major depression...
Post-traumatic stress disorder and serotonin: new directions for research and treatmentL L Davis
Veterans Affairs Medical Center, Tuscaloosa, AL 35404, USA
J Psychiatry Neurosci 22:318-26. 1997..Further investigation of a serotonergic dysfunction in PTSD and of its treatment with serotonergic agents is warranted...
Clonazepam for treatment of sleep disturbances associated with combat-related posttraumatic stress disorderMarshall E Cates
McWhorter School of Pharmacy, Samford University, Birmingham, AL 35229 7027, USA
Ann Pharmacother 38:1395-9. 2004..Clonazepam is widely used for the treatment of posttraumatic stress disorder (PTSD)-related sleep disturbances despite very limited published data supporting its use for this indication...
Selecting among second-step antidepressant medication monotherapies: predictive value of clinical, demographic, or first-step treatment featuresA John Rush
Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
Arch Gen Psychiatry 65:870-80. 2008..Little is known about selecting among second-step medications for major depressive disorder after intolerance or lack of remission with an initial selective serotonin reuptake inhibitor...
Divalproex in the treatment of posttraumatic stress disorder: a randomized, double-blind, placebo-controlled trial in a veteran populationLori L Davis
Veterans Affairs Medical Center, Tuscaloosa, AL 35404, USA
J Clin Psychopharmacol 28:84-8. 2008..To evaluate the efficacy of divalproex for the treatment of posttraumatic stress disorder (PTSD) hyperarousal symptom cluster...
Are depressed outpatients with and without a family history of substance use disorder different? A baseline analysis of the STAR*D cohortLori L Davis
Department of Veterans Affairs VA Medical Center, Tuscaloosa, Ala 35404, USA
J Clin Psychiatry 68:1931-8. 2007....
A pharmacokinetic and clinical evaluation of switching patients with bipolar I disorder from delayed-release to extended-release divalproexLori L Davis
Research and Development Department, Tuscaloosa VA Medical Center, Tuscaloosa, AL 35404, USA
J Clin Psychiatry 68:1546-51. 2007..To determine the optimal strategy for converting stable bipolar patients from twice-daily divalproex delayed release (DR) to once-daily divalproex extended release (ER)...
Insured and non-insured depressed outpatients: how do they compare?Ira M Lesser
Department of Psychiatry, Harbor UCLA Medical Center, The Los Angeles Biomedical Research Institute, Los Angeles, CA, USA
Ann Clin Psychiatry 19:73-82. 2007....
Valproate therapy for chronic, combat-induced posttraumatic stress disorderFrederick Petty
J Clin Psychopharmacol 22:100-1. 2002
Long-term pharmacotherapy for post-traumatic stress disorderLori L Davis
VA Medical Center, Tuscaloosa, Alabama 35404, USA
CNS Drugs 20:465-76. 2006..The effect of other agents (atypical antipsychotics, AEDs and other psychotropic medications) requires further controlled study...
Treatment of chronic posttraumatic stress disorder in combat veterans with citalopram: an open trialBrett A English
Department of Pharmacology, Center for Molecular Neuroscience, Graduate Program in Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, USA
J Clin Psychopharmacol 26:84-8. 2006..Further study in a larger and more diverse patient sample is warranted prior to final conclusions on efficacy of citalopram for the treatment of PTSD...
Baclofen treatment for chronic posttraumatic stress disorderRoger G Drake
Clinical Pharmacy, Bryce Hospital, Tuscaloosa, AL, USA
Ann Pharmacother 37:1177-81. 2003..Larger, double-blind, placebo-controlled studies are needed to confirm the efficacy of baclofen in the treatment of PTSD...
Lithium regulates glycogen synthase kinase-3beta in human peripheral blood mononuclear cells: implication in the treatment of bipolar disorderXiaohua Li
Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294 0017, USA
Biol Psychiatry 61:216-22. 2007..We tested whether lithium modified GSK3beta in vivo or in vitro in peripheral blood mononuclear cells (PBMCs) from healthy control and bipolar disorder subjects...
Characteristics of insured and noninsured outpatients with depression in STAR(*)DIra M Lesser
Harbor UCLA Medical Center, Box 8, 1000 West Carson Street, Torrance, California 90509, USA
Psychiatr Serv 56:995-1004. 2005....
