Roy Davis Altman

Summary

Affiliation: David Geffen School of Medicine
Country: USA

Publications

  1. pmc Heritability patterns in hand osteoarthritis: the role of osteophytes
    Mariko L Ishimori
    Division of Rheumatology, Cedars Sinai Medical Center, 8700 Beverly Blvd, B 131, Los Angeles, CA 90048, USA
    Arthritis Res Ther 12:R180. 2010
  2. pmc Correlation of pain relief with physical function in hand osteoarthritis: randomized controlled trial post hoc analysis
    H Richard Barthel
    Private Practice Rheumatology, P, O, Box 30813, Santa Barbara, CA 93130, USA
    Arthritis Res Ther 12:R7. 2010
  3. ncbi request reprint Measurement of structural progression in osteoarthritis of the hip: the Barcelona consensus group
    R D Altman
    Division of Rheumatology, David Geffen School of Medicine at the University of California at Los Angeles, Los Angeles, CA, USA
    Osteoarthritis Cartilage 12:515-24. 2004
  4. ncbi request reprint Practical considerations for the pharmacologic management of osteoarthritis
    Roy Davis Altman
    Am J Manag Care 15:S236-43. 2009
  5. doi request reprint Diclofenac sodium gel in patients with primary hand osteoarthritis: a randomized, double-blind, placebo-controlled trial
    Roy D Altman
    Department of Rheumatology and Immunology, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    J Rheumatol 36:1991-9. 2009
  6. doi request reprint A double-blind, randomized, saline-controlled study of the efficacy and safety of EUFLEXXA for treatment of painful osteoarthritis of the knee, with an open-label safety extension (the FLEXX trial)
    Roy D Altman
    Division of Rheumatology and Immunology, University of California Los Angeles, Los Angeles, CA 90095, USA
    Semin Arthritis Rheum 39:1-9. 2009
  7. ncbi request reprint Structure-/disease-modifying agents for osteoarthritis
    Roy D Altman
    Division of Rheumatology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA
    Semin Arthritis Rheum 34:3-5. 2005
  8. doi request reprint Topical therapy for osteoarthritis: clinical and pharmacologic perspectives
    Roy Altman
    David Geffen School of Medicine, Department of Rheumatology and Immunology, University of California, Los Angeles, CA 90024, USA
    Postgrad Med 121:139-47. 2009
  9. ncbi request reprint Three-month efficacy and safety of acetaminophen extended-release for osteoarthritis pain of the hip or knee: a randomized, double-blind, placebo-controlled study
    R D Altman
    David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    Osteoarthritis Cartilage 15:454-61. 2007
  10. ncbi request reprint Glucosamine therapy for knee osteoarthritis: pharmacokinetic considerations
    Roy D Altman
    Professor of Medicine, University of California at Los Angeles, Los Angeles, CA, USA
    Expert Rev Clin Pharmacol 2:359-71. 2009

Collaborators

Detail Information

Publications35

  1. pmc Heritability patterns in hand osteoarthritis: the role of osteophytes
    Mariko L Ishimori
    Division of Rheumatology, Cedars Sinai Medical Center, 8700 Beverly Blvd, B 131, Los Angeles, CA 90048, USA
    Arthritis Res Ther 12:R180. 2010
    ..The objective of the present study was to assess heritability of clinical and radiographic features of hand osteoarthritis (OA) in affected patients and their siblings...
  2. pmc Correlation of pain relief with physical function in hand osteoarthritis: randomized controlled trial post hoc analysis
    H Richard Barthel
    Private Practice Rheumatology, P, O, Box 30813, Santa Barbara, CA 93130, USA
    Arthritis Res Ther 12:R7. 2010
    ..The current analysis examined the relationship of pain relief with measures of function and global rating of disease in patients with hand OA...
  3. ncbi request reprint Measurement of structural progression in osteoarthritis of the hip: the Barcelona consensus group
    R D Altman
    Division of Rheumatology, David Geffen School of Medicine at the University of California at Los Angeles, Los Angeles, CA, USA
    Osteoarthritis Cartilage 12:515-24. 2004
    ..To outline the best available method of measurement for detecting progression of osteoarthritis (OA) of the hip especially in therapeutic trials...
  4. ncbi request reprint Practical considerations for the pharmacologic management of osteoarthritis
    Roy Davis Altman
    Am J Manag Care 15:S236-43. 2009
    ....
  5. doi request reprint Diclofenac sodium gel in patients with primary hand osteoarthritis: a randomized, double-blind, placebo-controlled trial
    Roy D Altman
    Department of Rheumatology and Immunology, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    J Rheumatol 36:1991-9. 2009
    ..To measure the efficacy and safety of diclofenac sodium gel in patients with primary hand osteoarthritis (OA)...
  6. doi request reprint A double-blind, randomized, saline-controlled study of the efficacy and safety of EUFLEXXA for treatment of painful osteoarthritis of the knee, with an open-label safety extension (the FLEXX trial)
    Roy D Altman
    Division of Rheumatology and Immunology, University of California Los Angeles, Los Angeles, CA 90095, USA
    Semin Arthritis Rheum 39:1-9. 2009
    ..To report the FLEXX trial, the first well-controlled study assessing the safety and efficacy of Euflexxa (1% sodium hyaluronate; IA-BioHA) therapy for knee osteoarthritis (OA) at 26 weeks...
  7. ncbi request reprint Structure-/disease-modifying agents for osteoarthritis
    Roy D Altman
    Division of Rheumatology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA
    Semin Arthritis Rheum 34:3-5. 2005
    ..This has led to increasing interest in structure/disease modification as the goal in OA therapy. However, there are no universally proven structure-/ disease-modifying interventions...
  8. doi request reprint Topical therapy for osteoarthritis: clinical and pharmacologic perspectives
    Roy Altman
    David Geffen School of Medicine, Department of Rheumatology and Immunology, University of California, Los Angeles, CA 90024, USA
    Postgrad Med 121:139-47. 2009
    ..This review discusses the pharmacology, clinical efficacy, and safety profiles of diclofenac sodium 1% gel, salicylates, and capsaicin for the management of hand and knee OA...
  9. ncbi request reprint Three-month efficacy and safety of acetaminophen extended-release for osteoarthritis pain of the hip or knee: a randomized, double-blind, placebo-controlled study
    R D Altman
    David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    Osteoarthritis Cartilage 15:454-61. 2007
    ..To examine the efficacy and safety of two doses of long-acting acetaminophen in patients with osteoarthritis (OA) of the hip or knee...
  10. ncbi request reprint Glucosamine therapy for knee osteoarthritis: pharmacokinetic considerations
    Roy D Altman
    Professor of Medicine, University of California at Los Angeles, Los Angeles, CA, USA
    Expert Rev Clin Pharmacol 2:359-71. 2009
    ..This review describes the current knowledge regarding the pharmacokinetics of glucosamine to provide a means for the interpretation of the pharmacodynamic and clinical efficacy results obtained in the different clinical trials...
  11. ncbi request reprint Early management of osteoarthritis
    Roy Davis Altman
    Am J Manag Care 16:S41-7. 2010
    ..Several societies have developed therapeutic guidelines, with general overall agreement between publications. Therapy of OA is multimodal and requires a combination of pharmacologic and nonpharmacologic treatments...
  12. doi request reprint Pharmacologic treatment of knee osteoarthritis in athletic women
    Roy D Altman
    Department of Rheumatology and Immunology, University of California, Los Angeles, CA, USA
    Phys Sportsmed 39:39-44. 2011
    ..These findings, along with additional future studies, may have particular relevance to the choice of the most effective treatment options for athletic women with OA of the knee...
  13. doi request reprint Safety and efficacy of retreatment with a bioengineered hyaluronate for painful osteoarthritis of the knee: results of the open-label Extension Study of the FLEXX Trial
    R D Altman
    Division of Rheumatology and Immunology, Department of Medicine, University of California Los Angeles, Los Angeles, CA 90024, United States
    Osteoarthritis Cartilage 19:1169-75. 2011
    ..To evaluate the safety of repeated intra-articular (IA) injections of Euflexxa® (1% sodium hyaluronate; IA--BioHA) for painful knee osteoarthritis (OA)...
  14. doi request reprint Topical therapies for osteoarthritis
    Roy D Altman
    David Geffen School of Medicine, Department of Rheumatology and Immunology, University of California, Los Angeles, 90024, USA
    Drugs 71:1259-79. 2011
    ....
  15. doi request reprint Opioid therapy for osteoarthritis and chronic low back pain
    Roy D Altman
    Department of Rheumatology and Immunology, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    Postgrad Med 122:87-97. 2010
    ..Opioids are prescribed more frequently for CLBP and OA than for any other noncancer pain, and the judicious use of opioids is recommended by treatment guidelines for the management of CLBP and OA pain...
  16. doi request reprint New guidelines for topical NSAIDs in the osteoarthritis treatment paradigm
    Roy D Altman
    David Geffen School of Medicine, University of California, Los Angeles, CA, USA
    Curr Med Res Opin 26:2871-6. 2010
    ..For example, nonsteroidal anti-inflammatory drugs (NSAIDs) are associated with cardiovascular, gastrointestinal, and renal adverse events. Topical NSAIDs offer efficacy with reduced systemic drug exposure...
  17. ncbi request reprint Measurement of structure (disease) modification in osteoarthritis
    R D Altman
    Professor of Medicine, University of Miami, Miami, Florida 33125, USA
    Osteoarthritis Cartilage 12:S69-76. 2004
    ..It may be that the radiograph will not achieve the needed degree of validation and will be supplanted by magnetic resonance imaging as the surrogate marker of joint status...
  18. ncbi request reprint Non-avian-derived hyaluronan for the treatment of osteoarthritis of the knee
    Roy D Altman
    David Geffen School of Medicine, University of California, Los Angeles, CA, USA
    Expert Rev Clin Immunol 6:21-7. 2010
    ....
  19. ncbi request reprint Atlas of individual radiographic features in osteoarthritis, revised
    R D Altman
    The David Geffen School of Medicine, The University of California at Los Angeles, Los Angeles, CA 91390, USA
    Osteoarthritis Cartilage 15:A1-56. 2007
    ..Develop a radiographic atlas of osteoarthritis (OA) to be used as a template and guide for grading radiographs of osteoarthritic lesions of the hand, hip and knee...
  20. ncbi request reprint Total joint replacement of hip or knee as an outcome measure for structure modifying trials in osteoarthritis
    R D Altman
    Rheumatology and Immunology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Osteoarthritis Cartilage 13:13-9. 2005
    ....
  21. ncbi request reprint Intraarticular sodium hyaluronate (Hyalgan) in the treatment of patients with osteoarthritis of the knee: a randomized clinical trial. Hyalgan Study Group
    R D Altman
    Department of Rheumatology and Immunology, University of Miami, Florida, USA
    J Rheumatol 25:2203-12. 1998
    ..To determine efficacy and safety of intraarticular (IA) hyaluronic acid (HA; Hyalgan) versus placebo and a nonsteroidal antiinflammatory drug for osteoarthritis (OA) of the knee...
  22. ncbi request reprint A rationale for combining acetaminophen and NSAIDs for mild-to-moderate pain
    R D Altman
    David Geffen School of Medicine, University of California Los Angeles, 1000 Veteran Avenue, Rehabilitation Building, Box 951361, Los Angeles, CA 90024, USA
    Clin Exp Rheumatol 22:110-7. 2004
    ..Further studies are warranted to determine the clinical utility and safety of acetaminophen/NSAID combinations as analgesic therapy for common conditions associated with mild-to-moderate pain...
  23. ncbi request reprint Paget's disease of bone: rheumatologic complications
    R D Altman
    Miami VA Medical Center, Department of Medicine, University of Miami, Florida 33125, USA
    Bone 24:47S-48S. 1999
    ..Back pain is particularly common and one must be careful before attributing back pain to Paget's disease; otherwise, both the physician and patient may be disappointed in the results of therapy...
  24. ncbi request reprint Intra-articular sodium hyaluronate in osteoarthritis of the knee
    R D Altman
    Department of Rheumatology and Immunology, University of Miami School of Medicine, and the Geriatric Research, Education, and Clinical Center, VA Hospital, FL, USA
    Semin Arthritis Rheum 30:11-8. 2000
    ..To better understand the therapeutic role of HA, this review focuses on comparative clinical trial data...
  25. ncbi request reprint Safety and efficacy of intra-articular sodium hyaluronate (Hyalgan) in a randomized, double-blind study for osteoarthritis of the ankle
    Michael M Cohen
    Miami Veterans Affairs Medical Center, Surgical Service, 1201 NW 16th St, Miami, FL 33125, USA
    Foot Ankle Int 29:657-63. 2008
    ..This double-blind, randomized, controlled study examined the safety and efficacy of intraarticular sodium hyaluronate (Hyalgan) in the treatment of pain associated with ankle OA...
  26. ncbi request reprint Efficacy and safety of a single intra-articular injection of non-animal stabilized hyaluronic acid (NASHA) in patients with osteoarthritis of the knee
    Roy D Altman
    GRECC, Miami VAMC, Miami, FL, USA
    Osteoarthritis Cartilage 12:642-9. 2004
    ..This study compared the efficacy of a single injection of NASHA with placebo in patients with osteoarthritis (OA) of the knee...
  27. ncbi request reprint Status of hyaluronan supplementation therapy in osteoarthritis
    Roy D Altman
    Department of Rheumatology, University of Miami School of Medicine, PO Box 106960, FL 33101, USA
    Curr Rheumatol Rep 5:7-14. 2003
    ..Thus, compared with currently approved nonoperative therapies for osteoarthritis, hyaluronans may also have beneficial effects on the disease process in osteoarthritis...
  28. ncbi request reprint Inhibition of insulin-like growth factor binding protein 5 proteolysis in articular cartilage and joint fluid results in enhanced concentrations of insulin-like growth factor 1 and is associated with improved osteoarthritis
    David R Clemmons
    Division of Endocrinology, University of North Carolina, Chapel Hill, 27599 7170, USA
    Arthritis Rheum 46:694-703. 2002
    ....
  29. ncbi request reprint Outcome variables for osteoarthritis clinical trials: The OMERACT-OARSI set of responder criteria
    Thao Pham
    Rene Descartes University, AP HP, Rheumatology B Department, Cochin Hospital, Paris, France
    J Rheumatol 30:1648-54. 2003
    ..The conclusions of the task force were presented and discussed during the OMERACT 6 conference, where a simplified set of responder criteria (OMERACT-OARSI set of criteria) was proposed...
  30. ncbi request reprint Pain relief in osteoarthritis: the rationale for combination therapy
    Roy D Altman
    J Rheumatol 31:5-7. 2004
  31. ncbi request reprint Quantitative magnetic resonance imaging evaluation of knee osteoarthritis progression over two years and correlation with clinical symptoms and radiologic changes
    Jean Pierre Raynauld
    Centre Hospitalier de l Universite de Montreal, Hopital Notre Dame, and Université de Montréal, Montreal, Quebec, Canada
    Arthritis Rheum 50:476-87. 2004
    ..To evaluate the change in osteoarthritic (OA) knee cartilage volume over a two-year period with the use of magnetic resonance imaging (MRI) and to correlate the MRI changes with radiologic changes...
  32. ncbi request reprint Use of a permanent magnetic field to inhibit the development of canine osteoarthritis
    Richard A Rogachefsky
    Department of Orthopedics, University of Miami School of Medicine, Miami, Florida, USA
    Bioelectromagnetics 25:260-70. 2004
    ..Further studies are needed to delineate more precisely the effect of the magnetic field in reducing the severity of OA...
  33. ncbi request reprint Increased radiographic damage scores at the onset of seropositive rheumatoid arthritis in older patients are associated with osteoarthritis of the hands, but not with more rapid progression of damage
    Dinesh Khanna
    University of California at Los Angeles, USA
    Arthritis Rheum 52:2284-92. 2005
    ..To investigate the impact of patient age at symptom onset on radiographic joint damage at study entry, and on subsequent progression of damage in a cohort of patients with early seropositive rheumatoid arthritis (RA)...
  34. ncbi request reprint Recommendations for the registration of agents to be used in the prevention and treatment of glucocorticoid-induced osteoporosis: updated recommendations from the Group for the Respect of Ethics and Excellence in Science
    Eric C Abadie
    Department of Public Health, Epidemiology, and Health Economics, University of Liege, Liege, Belgium
    Semin Arthritis Rheum 35:1-4. 2005
    ....
  35. ncbi request reprint Reversible posterior leukoencephalopathy in patients with systemic lupus erythematosus
    Molly D Magnano
    Division of Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, CA, USA
    Semin Arthritis Rheum 35:396-402. 2006
    ..Conditions commonly associated with RPLE include hypertensive encephalopathy, eclampsia, immunosuppressive drugs, and inflammatory disorders...