Anna Tosteson

Summary

Affiliation: Dartmouth Medical School
Country: USA

Publications

  1. ncbi Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT): a randomized trial
    James N Weinstein
    Dartmouth Medical School, Hanover, NH, USA
    JAMA 296:2441-50. 2006
  2. ncbi Comparative effectiveness evidence from the spine patient outcomes research trial: surgical versus nonoperative care for spinal stenosis, degenerative spondylolisthesis, and intervertebral disc herniation
    Anna N A Tosteson
    The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Medical School, Lebanon, NH 03756, USA
    Spine (Phila Pa 1976) 36:2061-8. 2011
  3. ncbi Cost-effectiveness of digital mammography breast cancer screening
    Anna N A Tosteson
    The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Medical School, Lebanon, New Hampshire 03756, USA
    Ann Intern Med 148:1-10. 2008
  4. ncbi Cost-effective osteoporosis treatment thresholds: the United States perspective
    A N A Tosteson
    Multidisciplinary Clinical Research Center in Musculoskeletal Diseases and The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Medical School, Lebanon, NH 03756, USA
    Osteoporos Int 19:437-47. 2008
  5. ncbi Therapies for treatment of osteoporosis in US women: cost-effectiveness and budget impact considerations
    Anna N A Tosteson
    Department of Medicine, Dartmouth Medical School, and The Dartmouth Institute of Health Policy and Clinical Practice ANAT, Lebanon, NH 03756, USA
    Am J Manag Care 14:605-15. 2008
  6. ncbi Characterizing preferences for health outcomes in economic evaluations
    Anna N Tosteson
    Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire, USA
    J Rheumatol Suppl 68:15-8. 2003
  7. ncbi Preference-based health outcome measures in low back pain
    A N Tosteson
    Department of Medicine and the Center for Evaluative Clinical Sciences, Dartmouth Medical School, Hanover, New Hampshire, USA
    Spine (Phila Pa 1976) 25:3161-6. 2000
  8. ncbi Early discontinuation of treatment for osteoporosis
    Anna N A Tosteson
    Department of Medicine, Dartmouth Medical School, Hannover, New Hampshire 03756, USA
    Am J Med 115:209-16. 2003
  9. ncbi Persistence and switching patterns among women with varied osteoporosis medication histories: 12-month results from POSSIBLE US
    A N A Tosteson
    HB 7505 Clinical Research, Dartmouth Medical School, 1 Medical Center Drive, Lebanon, NH 03756, USA
    Osteoporos Int 21:1769-80. 2010
  10. ncbi Automated current health time-trade-off assessments in women's health
    Anna N A Tosteson
    Center for the Evaluative Clinical Sciences, Department of Community and Family Medicine, Dartmouth Medical School, Hanover, New Hampshire 03756, USA
    Value Health 5:98-105. 2002

Research Grants

  1. Comparative Effectiveness of Treatments for Degenerative Spine Disease
    Anna Tosteson; Fiscal Year: 2009
  2. EVALUATION OF OSTEOPOROSIS PREVENTION IN THE ELDERLY
    Anna Tosteson; Fiscal Year: 2006
  3. EVALUATION OF OSTEOPOROSIS PREVENTION IN THE ELDERLY
    Anna Tosteson; Fiscal Year: 2001
  4. Comparative Effectiveness of Treatments for Degenerative Spine Disease
    Anna N A Tosteson; Fiscal Year: 2010

Detail Information

Publications49

  1. ncbi Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT): a randomized trial
    James N Weinstein
    Dartmouth Medical School, Hanover, NH, USA
    JAMA 296:2441-50. 2006
    ..Lumbar diskectomy is the most common surgical procedure performed for back and leg symptoms in US patients, but the efficacy of the procedure relative to nonoperative care remains controversial...
  2. ncbi Comparative effectiveness evidence from the spine patient outcomes research trial: surgical versus nonoperative care for spinal stenosis, degenerative spondylolisthesis, and intervertebral disc herniation
    Anna N A Tosteson
    The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Medical School, Lebanon, NH 03756, USA
    Spine (Phila Pa 1976) 36:2061-8. 2011
    ..Cost-effectiveness analysis of a randomized plus observational cohort trial...
  3. ncbi Cost-effectiveness of digital mammography breast cancer screening
    Anna N A Tosteson
    The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Medical School, Lebanon, New Hampshire 03756, USA
    Ann Intern Med 148:1-10. 2008
    ....
  4. ncbi Cost-effective osteoporosis treatment thresholds: the United States perspective
    A N A Tosteson
    Multidisciplinary Clinical Research Center in Musculoskeletal Diseases and The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Medical School, Lebanon, NH 03756, USA
    Osteoporos Int 19:437-47. 2008
    ..A 3% 10-year risk of hip fracture was generally required for osteoporosis treatment to cost less than $60,000 per QALY gained...
  5. ncbi Therapies for treatment of osteoporosis in US women: cost-effectiveness and budget impact considerations
    Anna N A Tosteson
    Department of Medicine, Dartmouth Medical School, and The Dartmouth Institute of Health Policy and Clinical Practice ANAT, Lebanon, NH 03756, USA
    Am J Manag Care 14:605-15. 2008
    ..To evaluate the cost-effectiveness of osteoporosis treatments for women at high fracture risk and estimate the population-level impact of providing bisphosphonate therapy to all eligible high-risk US women...
  6. ncbi Characterizing preferences for health outcomes in economic evaluations
    Anna N Tosteson
    Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire, USA
    J Rheumatol Suppl 68:15-8. 2003
  7. ncbi Preference-based health outcome measures in low back pain
    A N Tosteson
    Department of Medicine and the Center for Evaluative Clinical Sciences, Dartmouth Medical School, Hanover, New Hampshire, USA
    Spine (Phila Pa 1976) 25:3161-6. 2000
    ..At present, there is little evidence to base choice of one system over another for assessing the cost-effectiveness of low back pain interventions...
  8. ncbi Early discontinuation of treatment for osteoporosis
    Anna N A Tosteson
    Department of Medicine, Dartmouth Medical School, Hannover, New Hampshire 03756, USA
    Am J Med 115:209-16. 2003
    ..To identify factors associated with early treatment discontinuation of three agents commonly prescribed for women with low bone density...
  9. ncbi Persistence and switching patterns among women with varied osteoporosis medication histories: 12-month results from POSSIBLE US
    A N A Tosteson
    HB 7505 Clinical Research, Dartmouth Medical School, 1 Medical Center Drive, Lebanon, NH 03756, USA
    Osteoporos Int 21:1769-80. 2010
    ..Participants not on stable therapy at entry, with side effects, and with poor physical status were at higher risk of transitioning. Understanding factors associated with persistence may lead to improved outcomes...
  10. ncbi Automated current health time-trade-off assessments in women's health
    Anna N A Tosteson
    Center for the Evaluative Clinical Sciences, Department of Community and Family Medicine, Dartmouth Medical School, Hanover, New Hampshire 03756, USA
    Value Health 5:98-105. 2002
    ....
  11. ncbi Impact of hip and vertebral fractures on quality-adjusted life years
    A N Tosteson
    Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire, USA
    Osteoporos Int 12:1042-9. 2001
    ..Thus to adequately assess the cost-effectiveness of osteoporosis treatment, the negative impact of vertebral fractures on QALYs, even among women who have survived a hip fracture, must be considered...
  12. ncbi Excess mortality following hip fracture: the role of underlying health status
    A N A Tosteson
    Multidisciplinary Clinical Research Center in Musculoskeletal Diseases, Dartmouth Medical School, Lebanon, NH 03756, USA
    Osteoporos Int 18:1463-72. 2007
    ..S. elders. Although mortality was elevated for the first six months following hip fracture, we found no evidence of long-term excess mortality...
  13. ncbi Surgical versus nonoperative treatment for lumbar spinal stenosis four-year results of the Spine Patient Outcomes Research Trial
    James N Weinstein
    Department of Orthopaedics, Dartmouth Medical School, Hanover, NH 03756, USA
    Spine (Phila Pa 1976) 35:1329-38. 2010
    ..Randomized trial and concurrent observational cohort study...
  14. ncbi Patient preferences and expectations for care: determinants in patients with lumbar intervertebral disc herniation
    Jon D Lurie
    Dartmouth Medical School, Lebanon, NH 03756, USA
    Spine (Phila Pa 1976) 33:2663-8. 2008
    ..Prospective observational cohort...
  15. ncbi Distal radial fracture treatment: what you get may depend on your age and address
    Jason Fanuele
    Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
    J Bone Joint Surg Am 91:1313-9. 2009
    ..S. Medicare population stratified by hospital referral region and (2) whether the type of fracture treatment is affected by patient age, race, sex, comorbidity, or hospital referral region...
  16. ncbi Surgical treatment of spinal stenosis with and without degenerative spondylolisthesis: cost-effectiveness after 2 years
    Anna N A Tosteson
    Multidisciplinary Clinical Research Center in Musculoskeletal Diseases, Dartmouth Medical School, Hanover, New Hampshire 03756, USA
    Ann Intern Med 149:845-53. 2008
    ..The SPORT (Spine Patient Outcomes Research Trial) reported favorable surgery outcomes over 2 years among patients with stenosis with and without degenerative spondylolisthesis, but the economic value of these surgeries is uncertain...
  17. ncbi Degenerative spondylolisthesis: does fusion method influence outcome? Four-year results of the spine patient outcomes research trial
    William A Abdu
    Departments of Orthopaedics, Dartmouth Medical School, Dartmouth College, Hanover, NH 03756, USA
    Spine (Phila Pa 1976) 34:2351-60. 2009
    ..Clinical trial subgroup analysis...
  18. ncbi The cost effectiveness of surgical versus nonoperative treatment for lumbar disc herniation over two years: evidence from the Spine Patient Outcomes Research Trial (SPORT)
    Anna N A Tosteson
    Dartmouth Medical School, Hanover, NH 03756, USA anna tosteson dartmouth edu
    Spine (Phila Pa 1976) 33:2108-15. 2008
    ....
  19. ncbi Comparison of EQ-5D, HUI, and SF-36-derived societal health state values among spine patient outcomes research trial (SPORT) participants
    Christine M McDonough
    Dartmouth Medical School, Community and Family Medicine, Multidisciplinary Clinical Research Center in Musculoskeletal Diseases and the Center for Evaluative Clinical Sciences, Lebanon, NH 03756, USA
    Qual Life Res 14:1321-32. 2005
    ..Caution should be used when comparing health state values derived from various systems...
  20. ncbi Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT) observational cohort
    James N Weinstein
    Dartmouth Medical School, Hanover, NH, USA
    JAMA 296:2451-9. 2006
    ..However, the large numbers of patients who crossed over between assigned groups precluded any conclusions about the comparative effectiveness of operative therapy vs usual care...
  21. ncbi Surgical compared with nonoperative treatment for lumbar degenerative spondylolisthesis. four-year results in the Spine Patient Outcomes Research Trial (SPORT) randomized and observational cohorts
    James N Weinstein
    Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    J Bone Joint Surg Am 91:1295-304. 2009
    ..Questions remain regarding the long-term effects of surgical treatment compared with those of nonoperative treatment...
  22. ncbi Magnetic resonance imaging interpretation in patients with symptomatic lumbar spine disc herniations: comparison of clinician and radiologist readings
    Jon D Lurie
    Department of Medicine, Dartmouth Medical School, 1 Medical Center Drive, Lebanon, NH 03756, USA
    Spine (Phila Pa 1976) 34:701-5. 2009
    ..Retrospective review of imaging data from a clinical trial...
  23. ncbi Surgical versus nonoperative treatment for lumbar disc herniation: four-year results for the Spine Patient Outcomes Research Trial (SPORT)
    James N Weinstein
    Department of Orthopaedics, Dartmouth Medical School, Hanover, NH 03756, USA
    Spine (Phila Pa 1976) 33:2789-800. 2008
    ..Concurrent, prospective, randomized, and observational cohort study...
  24. ncbi Likelihood of additional work-up among women undergoing routine screening mammography: the impact of age, breast density, and hormone therapy use
    Patricia A Carney
    Department of Community and Family Medicine, Dartmouth Medical School, Hanover Lebanon, NH 03755, USA
    Prev Med 39:48-55. 2004
    ..Understanding the likelihood of different events that follow initial screening is important if women and their health care providers are to be accurately informed about the screening process...
  25. ncbi Breast cancer risk factors in relation to breast density (United States)
    Linda Titus-Ernstoff
    Dartmouth Hitchcock Medical Center, One Medical Center, Lebanon, NH 03756, USA
    Cancer Causes Control 17:1281-90. 2006
    ..Evaluate known breast cancer risk factors in relation to breast density...
  26. ncbi Reliability of magnetic resonance imaging readings for lumbar disc herniation in the Spine Patient Outcomes Research Trial (SPORT)
    Jon D Lurie
    Department of Medicine, Dartmouth Medical School, Lebanon, New Hampshire 03756, USA
    Spine (Phila Pa 1976) 33:991-8. 2008
    ..Assessment of the reliability of standardized magnetic resonance imaging (MRI) interpretations and measurements...
  27. ncbi Surgical versus nonsurgical therapy for lumbar spinal stenosis
    James N Weinstein
    Dartmouth Institute for Health Policy and Clinical Practice, Department of Orthopedics, Dartmouth Medical School, Hanover, NH 03756, USA
    N Engl J Med 358:794-810. 2008
    ..Surgery for spinal stenosis is widely performed, but its effectiveness as compared with nonsurgical treatment has not been shown in controlled trials...
  28. ncbi Hormone therapies in women aged 40 and older: prevalence and correlates of use
    Patricia A Carney
    Department of Community and Family Medicine, Dartmouth Medical School, 1 Medical Center Dr HB 7925, Lebanon, NH 03756, USA
    Maturitas 53:65-76. 2006
    ..DESIGN/SETTING/SAMPLE: Cross-sectional baseline study from a prospective cohort of 30,448 women receiving mammography in New Hampshire...
  29. ncbi Surgical versus nonsurgical treatment for lumbar degenerative spondylolisthesis
    James N Weinstein
    Department of Orthopaedics, Dartmouth Medical School, Lebanon, NH, USA
    N Engl J Med 356:2257-70. 2007
    ..Management of degenerative spondylolisthesis with spinal stenosis is controversial. Surgery is widely used, but its effectiveness in comparison with that of nonsurgical treatment has not been demonstrated in controlled trials...
  30. ncbi A longitudinal comparison of 5 preference-weighted health state classification systems in persons with intervertebral disk herniation
    Christine M McDonough
    Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth College, Lebanon, New Hampshire 03756, USA
    Med Decis Making 31:270-80. 2011
    ..To assess the longitudinal validity of widely used preference-weighted measurement systems for economic studies of intervertebral disk herniation (IDH)...
  31. ncbi The treatment of disabling intermittent claudication in patients with superficial femoral artery occlusive disease--decision analysis
    Brian Nolan
    Center for Evaluative Clinical Sciences, Dartmouth Medical School, Division of Vascular Surgery Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    J Vasc Surg 45:1179-84. 2007
    ..To determine the preferred approach to superficial femoral artery (SFA) revascularization of Trans-Atlantic Inter-Societal Consensus (TASC) B and C lesions in claudicants requiring intervention based on a review of published data...
  32. ncbi Screening mammography: costs and use of screening-related services
    Steven P Poplack
    Department of Radiology, Dartmouth Medical School, Dartmouth Hitchcock Medical Center, 1 Medical Center Dr, HB 7999, Lebanon, NH 03756, USA
    Radiology 234:79-85. 2005
    ..To determine the costs and screening-related services in women undergoing screening mammography...
  33. ncbi Prognostic imaging in neoadjuvant chemotherapy of locally-advanced breast cancer should be cost-effective
    Marc Schegerin
    Amos Tuck School of Business, Dartmouth College, Hanover, NH 03755, USA
    Breast Cancer Res Treat 114:537-47. 2009
    ..Prognostic imaging of response to therapy early in the course of a planned chemotherapy regimen could be of considerable value, particularly if shifting to another therapy regimen would be more effective...
  34. ncbi Strategies for distributing cancer screening decision aids in primary care
    Charles Brackett
    Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Patient Educ Couns 78:166-8. 2010
    ..Decision aids (DAs) have been shown to facilitate shared decision making about cancer screening. However, little data exist on optimal strategies for dissemination. Our objective was to compare different decision aid distribution models...
  35. ncbi Is prophylactic fixation a cost-effective method to prevent a future contralateral fragility hip fracture?
    Scott C Faucett
    Dartmouth Hitchcock Medical Center, Department of Orthopaedic Surgery, Lebanon, New Hampshire 03756, USA
    J Orthop Trauma 24:65-74. 2010
    ..The purpose of this study was to examine the cost-effectiveness of prophylactic fixation of the uninjured hip to prevent contralateral hip fracture...
  36. ncbi Measuring preferences for cost-utility analysis: how choice of method may influence decision-making
    Christine M McDonough
    Dartmouth Medical School, Multidisciplinary Clinical Research Center in Musculoskeletal Diseases, Lebanon, New Hampshire 03756, USA
    Pharmacoeconomics 25:93-106. 2007
    ..Consistent reporting of such analyses would provide further insight into the policy implications of preference measurement...
  37. ncbi Is surgery for displaced, midshaft clavicle fractures in adults cost-effective? Results based on a multicenter randomized, controlled trial
    Adam M Pearson
    Dartmouth Hitchcock Medical Center, Lebanon, NH 03755, USA
    J Orthop Trauma 24:426-33. 2010
    ..To determine the cost-effectiveness of open reduction internal fixation (ORIF) of displaced, midshaft clavicle fractures in adults...
  38. ncbi Quality-of-life assessment in osteoporosis: health-status and preference-based measures
    Anna N A Tosteson
    Clinical Research Section, Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire 03756, USA
    Pharmacoeconomics 20:289-303. 2002
    ..In addition, the longitudinal impact of osteoporosis and related fractures on HR-QOL must be documented...
  39. ncbi Design of the Spine Patient outcomes Research Trial (SPORT)
    Nancy J O Birkmeyer
    Department of Surgery, Community and Family Medicine, Clinical Trials Center, Dartmouth Medical School, Lebanon
    Spine 27:1361-72. 2002
    ..CONCLUSIONS: The results of this study will provide high-quality scientific evidence to aid clinical decision-making and improve treatment outcomes for these common, costly, and, in some instances, debilitating conditions...
  40. ncbi Comorbidity risk-adjustment strategies are comparable among persons with hip fracture
    David C Radley
    The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH 03756, USA
    J Clin Epidemiol 61:580-7. 2008
    ....
  41. ncbi Is early internal fixation preferred to cast treatment for well-reduced unstable distal radial fractures?
    Karl M Koenig
    Department of Orthopaedics, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    J Bone Joint Surg Am 91:2086-93. 2009
    ..This study was performed to evaluate whether early internal fixation or nonoperative treatment would be preferred for displaced, potentially unstable distal radial fractures that initially had an adequate reduction...
  42. ncbi The need for microsimulation to evaluate osteoporosis interventions
    David J Vanness
    Department of Population Health Sciences, University of Wisconsin Medical School, Madison, WI 53726, USA
    Osteoporos Int 16:353-8. 2005
    ..However, evaluations based on structural microsimulation may ultimately provide substantially more useful information, resulting in improved decision making...
  43. ncbi Diagnostic accuracy of digital versus film mammography: exploratory analysis of selected population subgroups in DMIST
    Etta D Pisano
    Department of Radiology, UNC Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7510, USA
    Radiology 246:376-83. 2008
    ....
  44. ncbi American College of Radiology Imaging Network digital mammographic imaging screening trial: objectives and methodology
    Etta D Pisano
    Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, NC, USA
    Radiology 236:404-12. 2005
    ....
  45. ncbi Effect of the Women's Health Initiative on women's decisions to discontinue postmenopausal hormone therapy
    Bruce Ettinger
    Division of Research, Kaiser Permanente Northern California, Oakland, Oakland, California 94611 5714, USA
    Obstet Gynecol 102:1225-32. 2003
    ....
  46. ncbi Predictors of difficulty when discontinuing postmenopausal hormone therapy
    Deborah Grady
    Department of Epidemiology and Biostatistics, University of California, San Francisco, USA
    Obstet Gynecol 102:1233-9. 2003
    ..To describe the experiences of postmenopausal women who try to stop hormone therapy and to identify characteristics associated with inability to stop...
  47. ncbi Impact of hospital volume on the economic value of computer navigation for total knee replacement
    James D Slover
    Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, 301 East 17th Street, Suite 1616, New York, NY 10010, USA
    J Bone Joint Surg Am 90:1492-500. 2008
    ..The purpose of this study was to examine the impact of hospital volume on the cost-effectiveness of this new technology in order to determine its feasibility and the level of evidence that should be sought prior to its adoption...
  48. ncbi A revised clinician's guide to the prevention and treatment of osteoporosis
    Bess Dawson-Hughes
    Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Clin Endocrinol Metab 93:2463-5. 2008
  49. ncbi Mortality, disability, and nursing home use for persons with and without hip fracture: a population-based study
    Cynthia L Leibson
    Department of Health Sciences Research, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    J Am Geriatr Soc 50:1644-50. 2002
    ..To compare persons with and without hip fracture for subsequent mortality and change in disability and nursing home (NH) use...

Research Grants13

  1. Comparative Effectiveness of Treatments for Degenerative Spine Disease
    Anna Tosteson; Fiscal Year: 2009
    ....
  2. EVALUATION OF OSTEOPOROSIS PREVENTION IN THE ELDERLY
    Anna Tosteson; Fiscal Year: 2006
    ..Our proposed research will provide results useful in guiding both osteoporosis-related health policy and patient-centered decision making. ..
  3. EVALUATION OF OSTEOPOROSIS PREVENTION IN THE ELDERLY
    Anna Tosteson; Fiscal Year: 2001
    ..These results will be useful in prioritizing areas for future research. With the advent of costly new therapies for osteoporosis, such data can help inform policy regarding the optimal use of these agents. ..
  4. Comparative Effectiveness of Treatments for Degenerative Spine Disease
    Anna N A Tosteson; Fiscal Year: 2010
    ....