Linda Titus-Ernstoff

Summary

Affiliation: Dartmouth Medical School
Country: USA

Publications

  1. pmc Mortality in women given diethylstilbestrol during pregnancy
    L Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School, and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Br J Cancer 95:107-11. 2006
  2. ncbi request reprint Early life factors in relation to breast cancer risk in postmenopausal women
    Linda Titus-Ernstoff
    Norris Cotton Cancer Center and the Department of Community and Family Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Cancer Epidemiol Biomarkers Prev 11:207-10. 2002
  3. doi request reprint Offspring of women exposed in utero to diethylstilbestrol (DES): a preliminary report of benign and malignant pathology in the third generation
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School, and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Epidemiology 19:251-7. 2008
  4. ncbi request reprint Multiple primary melanoma: two-year results from a population-based study
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH 03756, USA
    Arch Dermatol 142:433-8. 2006
  5. ncbi request reprint Pigmentary characteristics and moles in relation to melanoma risk
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Int J Cancer 116:144-9. 2005
  6. ncbi request reprint Menstrual and reproductive characteristics of women whose mothers were exposed in utero to diethylstilbestrol (DES)
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School, and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Int J Epidemiol 35:862-8. 2006
  7. ncbi request reprint Factors associated with atypical moles in New Hampshire, USA
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Acta Derm Venereol 87:43-8. 2007
  8. doi request reprint Longitudinal study of viewing smoking in movies and initiation of smoking by children
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, New Hampshire, USA
    Pediatrics 121:15-21. 2008
  9. pmc Birth defects in the sons and daughters of women who were exposed in utero to diethylstilbestrol (DES)
    L Titus-Ernstoff
    Departments of Community and Family Medicine and of Pediatrics, Dartmouth Medical School, and the Hood Center for Children and Families, Lebanon, NH 03756 USA
    Int J Androl 33:377-84. 2010
  10. pmc Breast-feeding the last born child and risk of ovarian cancer
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH 03756, USA
    Cancer Causes Control 21:201-7. 2010

Research Grants

  1. ATYPICAL NEVI IN MELANOMA--A CASE-CONTROL STUDY
    Linda Titus Ernstoff; Fiscal Year: 1999
  2. ATYPICAL NEVI IN MELANOMA--A CASE-CONTROL STUDY
    Linda Titus Ernstoff; Fiscal Year: 2000
  3. ATYPICAL NEVI IN MELANOMA--A CASE-CONTROL STUDY
    Linda Titus Ernstoff; Fiscal Year: 2001
  4. Melanoma Pathogenesis
    Linda Titus Ernstoff; Fiscal Year: 2004
  5. Melanoma Pathogenesis
    Linda Titus Ernstoff; Fiscal Year: 2005
  6. Melanoma Pathogenesis
    Linda Titus Ernstoff; Fiscal Year: 2006

Detail Information

Publications71

  1. pmc Mortality in women given diethylstilbestrol during pregnancy
    L Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School, and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Br J Cancer 95:107-11. 2006
    ..The association with breast cancer mortality was more evident in trial participants, who received high DES doses...
  2. ncbi request reprint Early life factors in relation to breast cancer risk in postmenopausal women
    Linda Titus-Ernstoff
    Norris Cotton Cancer Center and the Department of Community and Family Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Cancer Epidemiol Biomarkers Prev 11:207-10. 2002
    ..Overall, our results are consistent with previous studies and suggest that these early life factors have a modest influence on breast cancer risk in postmenopausal women...
  3. doi request reprint Offspring of women exposed in utero to diethylstilbestrol (DES): a preliminary report of benign and malignant pathology in the third generation
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School, and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Epidemiology 19:251-7. 2008
    ..Specifically, these studies show an elevated incidence of reproductive tumors in the female offspring of prenatally-exposed mice...
  4. ncbi request reprint Multiple primary melanoma: two-year results from a population-based study
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH 03756, USA
    Arch Dermatol 142:433-8. 2006
    ..To assess the frequency of occurrence and risk factors for multiple primary melanoma...
  5. ncbi request reprint Pigmentary characteristics and moles in relation to melanoma risk
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Int J Cancer 116:144-9. 2005
    ....
  6. ncbi request reprint Menstrual and reproductive characteristics of women whose mothers were exposed in utero to diethylstilbestrol (DES)
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School, and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Int J Epidemiol 35:862-8. 2006
    ..We report menstrual and reproductive characteristics in a unique cohort comprising daughters of women exposed prenatally to DES...
  7. ncbi request reprint Factors associated with atypical moles in New Hampshire, USA
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Acta Derm Venereol 87:43-8. 2007
    ..Our data indicate that freckles and benign moles, which may reflect melanocytic inducibility, are strongly associated with atypical moles. The inverse association with sun exposure should be considered with caution...
  8. doi request reprint Longitudinal study of viewing smoking in movies and initiation of smoking by children
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, New Hampshire, USA
    Pediatrics 121:15-21. 2008
    ..However, all studies except one were cross-sectional, and none updated movie smoking exposure prospectively or assessed its influence on children...
  9. pmc Birth defects in the sons and daughters of women who were exposed in utero to diethylstilbestrol (DES)
    L Titus-Ernstoff
    Departments of Community and Family Medicine and of Pediatrics, Dartmouth Medical School, and the Hood Center for Children and Families, Lebanon, NH 03756 USA
    Int J Androl 33:377-84. 2010
    ..We cannot, however, rule-out the possible influence of reporting bias. In particular, the exposed daughters' elevated risk of cardiac defects may be as a result of the underreporting of these conditions by unexposed mothers...
  10. pmc Breast-feeding the last born child and risk of ovarian cancer
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH 03756, USA
    Cancer Causes Control 21:201-7. 2010
    ..These findings, which require confirmation by future studies, imply that breast-feeding resets pregnancy-related states that mediate ovarian cancer risk...
  11. ncbi request reprint Psychosexual characteristics of men and women exposed prenatally to diethylstilbestrol
    Linda Titus-Ernstoff
    Dartmouth Hitchcock Medical Center, Dartmouth Medical School, and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Epidemiology 14:155-60. 2003
    ..The adverse effects of prenatal exposure on the genitourinary tract in men and the reproductive tract in women are well established, but the possible effects on psychosexual characteristics remain largely unknown...
  12. ncbi request reprint Effect of viewing smoking in movies on adolescent smoking initiation: a cohort study
    Madeline A Dalton
    Department of Paediatrics, Norris Cotton Cancer Center, Dartmouth Medical School, One Medical Center Drive, Lebanon 03756, USA
    Lancet 362:281-5. 2003
    ..Exposure to smoking in movies has been linked with adolescent smoking initiation in cross-sectional studies. We undertook a prospective study to ascertain whether exposure to smoking in movies predicts smoking initiation...
  13. ncbi request reprint Likelihood of additional work-up among women undergoing routine screening mammography: the impact of age, breast density, and hormone therapy use
    Patricia A Carney
    Department of Community and Family Medicine, Dartmouth Medical School, Hanover Lebanon, NH 03755, USA
    Prev Med 39:48-55. 2004
    ..Understanding the likelihood of different events that follow initial screening is important if women and their health care providers are to be accurately informed about the screening process...
  14. ncbi request reprint Utilization of screening mammography in New Hampshire: a population-based assessment
    Patricia A Carney
    Department of Community and Family Medicine, Dartmouth Medical School, Hanover, New Hampshire 03766, USA
    Cancer 104:1726-32. 2005
    ..Although self-report data indicate that screening utilization is high, the results of this population-based assessment indicated that utilization is lower than reported previously...
  15. ncbi request reprint Menarche, menopause, years of menstruation, and the incidence of osteoporosis: the influence of prenatal exposure to diethylstilbestrol
    Samantha E Parker
    Slone Epidemiology Center S E P, L A W, J R P, Boston University, Boston, Massachusetts 02215 Division of Cancer Epidemiology and Genetics R T, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 Departments of Community and Family Medicine and Pediatrics L T E, Dartmouth Medical School and the Norris Cotton Cancer Center, Lebanon, New Hampshire 03756 Department of Obstetrics and Gynecology W C S, Tufts Medical Center, Boston, Massachusetts 02111 and Department of Epidemiology L A W, J R P, E E H, Boston University School of Public Health, Boston, Massachusetts 02118
    J Clin Endocrinol Metab 99:594-601. 2014
    ..Estrogen is critical for bone formation and growth in women. Estrogen exposures occur throughout life, including prenatally, and change with reproductive events, such as menarche and menopause...
  16. pmc Perceived intrinsic barriers to physical activity among rural mothers
    Anna M Adachi-Mejia
    Community Health Research Program, Hood Center for Children and Families, Dartmouth Medical School, Lebanon, New Hampshire 03756 0001, USA
    J Womens Health (Larchmt) 19:2197-202. 2010
    ..The purpose of this study was to identify and determine the influence of perceived intrinsic barriers to physical activity among mothers living in rural areas...
  17. pmc Screening mammography intervals among postmenopausal hormone therapy users and nonusers
    Tracy Onega
    Department of Community and Family Medicine, Dartmouth Medical School, Hanover, NH, USA
    Cancer Causes Control 21:147-52. 2010
    ..To investigate the latter possibility, we compared mammographic intervals according to HT use...
  18. ncbi request reprint Screening mammography: costs and use of screening-related services
    Steven P Poplack
    Department of Radiology, Dartmouth Medical School, Dartmouth Hitchcock Medical Center, 1 Medical Center Dr, HB 7999, Lebanon, NH 03756, USA
    Radiology 234:79-85. 2005
    ..To determine the costs and screening-related services in women undergoing screening mammography...
  19. pmc Influence of movie smoking exposure and team sports participation on established smoking
    Anna M Adachi-Mejia
    Community Health Research Program, Hood Center for Children and Families, Dartmouth Medical School, One Medical Center Drive, Lebanon, NH 03756 0001, USA
    Arch Pediatr Adolesc Med 163:638-43. 2009
    ..To examine the joint effects of movie smoking exposure and team sports participation on established smoking...
  20. pmc Adolescent weight status and receptivity to food TV advertisements
    Anna M Adachi-Mejia
    Community Health Research Program, Hood Center for Children and Families, Dartmouth Medical School, Lebanon, NH 03756 0001, USA
    J Nutr Educ Behav 43:441-8. 2011
    ..This study examined the relationship between adolescent weight status and food advertisement receptivity...
  21. pmc Parental attitudes about cigarette smoking and alcohol use in the Motion Picture Association of America rating system
    Meghan R Longacre
    Department of Pediatrics, Dartmouth Medical School, Lebanon, NH 03756, USA
    Arch Pediatr Adolesc Med 163:218-24. 2009
    ..To evaluate whether parents want smoking and alcohol use to be considered in movie ratings...
  22. pmc Breast cancer risk factors in relation to breast density (United States)
    Linda Titus-Ernstoff
    Dartmouth Hitchcock Medical Center, One Medical Center, Lebanon, NH 03756, USA
    Cancer Causes Control 17:1281-90. 2006
    ..Evaluate known breast cancer risk factors in relation to breast density...
  23. pmc Early exposure to movie smoking predicts established smoking by older teens and young adults
    Madeline A Dalton
    Hood Center for Children and Families, Dartmouth Medical School, HB 7465, One Medical Center Dr, Lebanon, NH 03756, USA
    Pediatrics 123:e551-8. 2009
    ..We conducted a prospective study to determine whether movie smoking exposure during early adolescence predicts established smoking in older teens and young adults...
  24. ncbi request reprint Hormone therapies in women aged 40 and older: prevalence and correlates of use
    Patricia A Carney
    Department of Community and Family Medicine, Dartmouth Medical School, 1 Medical Center Dr HB 7925, Lebanon, NH 03756, USA
    Maturitas 53:65-76. 2006
    ..The objective of this paper is to report the prevalence and correlates of both prescription and non-prescription hormone use...
  25. ncbi request reprint Breast density in relation to risk of ductal carcinoma in situ of the breast in women undergoing screening mammography
    Todd A MacKenzie
    Department of Community and Family Medicine, Dartmouth Medical School, Norris Cotton Cancer Center, Hanover, NH, USA
    Cancer Causes Control 18:939-45. 2007
    ..To examine the association between breast density and risk of breast ductal carcinoma in situ (DCIS)...
  26. pmc Quality of life of long-term survivors of breast cancer and lymphoma treated with standard-dose chemotherapy or local therapy
    Tim A Ahles
    Department of Psychiatry and Center for Psycho Oncology Research, Dartmouth Hitchcock Medical Center, One Medical Center Dr, Lebanon, NH 03756, USA
    J Clin Oncol 23:4399-405. 2005
    ..This study compared the quality of life (QOL) of long-term survivors of breast cancer and lymphoma who had been treated with standard-dose systemic chemotherapy or local therapy only...
  27. ncbi request reprint Preeclampsia risk in women exposed in utero to diethylstilbestrol
    Rebecca Troisi
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Obstet Gynecol 110:113-20. 2007
    ..To assess whether preeclampsia risk is elevated in pregnancies of diethylstilbestrol (DES)-exposed daughters...
  28. ncbi request reprint Time to pregnancy and secondary sex ratio in men exposed prenatally to diethylstilbestrol
    Lauren A Wise
    Slone Epidemiology Center, Boston University, Boston, MA 02215, USA
    Am J Epidemiol 166:765-74. 2007
    ..92 (95% confidence interval: 0.80, 1.04) comparing the exposed with the unexposed. In conclusion, prenatal DES exposure was not associated with a significant decrease in either fecundability or secondary sex ratio...
  29. ncbi request reprint Genetic variation in TP53 and risk of breast cancer in a population-based case control study
    Brian L Sprague
    Department of Population Health Sciences, University of Wisconsin Madison, Madison, WI 53726, USA
    Carcinogenesis 28:1680-6. 2007
    ..03). These results indicate that common variation in the TP53 gene could modify the risk of invasive breast cancer...
  30. ncbi request reprint Cancer risk in women prenatally exposed to diethylstilbestrol
    Rebecca Troisi
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Int J Cancer 121:356-60. 2007
    ..Given that the population is still young, continued follow-up is necessary to assess the overall carcinogenic impact of prenatal DES exposure...
  31. pmc Ovarian cancer risk in relation to medical visits, pelvic examinations and type of health care provider
    Haim A Abenhaim
    School of Public Health, Harvard University, Boston, Mass, USA
    CMAJ 176:941-7. 2007
    ..Whether the current recommendations for ovarian cancer prevention and screening (annual history and physical examination) are effective has not been evaluated. We examined the relation between health care use and the risk of ovarian cancer...
  32. ncbi request reprint Cigarette smoking and risk of breast carcinoma in situ
    Amy Trentham-Dietz
    University of Wisconsin Paul P Carbone Comprehensive Cancer Center, Madison, Wisconsin 53726, USA
    Epidemiology 18:629-38. 2007
    ..Although the associations with cigarette smoking have been explored extensively for invasive breast cancer, the relation to in situ cancer has not previously been examined in depth...
  33. ncbi request reprint Oral contraceptive use and risk of breast carcinoma in situ
    Hazel B Nichols
    University of Wisconsin Paul P Carbone Comprehensive Cancer Center, University of Wisconsin, Madison, WI 53726, USA
    Cancer Epidemiol Biomarkers Prev 16:2262-8. 2007
    ..16; 95% CI, 1.01-1.32 for ever versus never use). Consistent with invasive breast cancer, these results suggest that oral contraceptive use is at most a minor contributor to BCIS risk...
  34. ncbi request reprint Statin use and risk of breast cancer
    Gaia Pocobelli
    Department of Epidemiology, University of Washington, Seattle, Washington, USA
    Cancer 112:27-33. 2008
    ..We analyzed data from a population-based case-control study to evaluate the association between the use of statins and breast cancer risk...
  35. pmc Talc use, variants of the GSTM1, GSTT1, and NAT2 genes, and risk of epithelial ovarian cancer
    Margaret A Gates
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:2436-44. 2008
    ..These results suggest that women with certain genetic variants may have a higher risk of ovarian cancer associated with genital talc use. Additional research is needed on these interactions and the underlying biological mechanisms...
  36. doi request reprint Exposure to sunlamps, tanning beds, and melanoma risk
    Kerri M Clough-Gorr
    Geriatrics Section, Department of Medicine, Boston University Medical Center, 88 East Newton Street, Robinson 2, Boston, MA, 02118, USA
    Cancer Causes Control 19:659-69. 2008
    ..To estimate the separate effects of sunlamp and tanning bed device use on melanoma risk...
  37. pmc Effects of birth order and maternal age on breast cancer risk: modification by whether women had been breast-fed
    Hazel B Nichols
    University of Wisconsin Paul P Carbone Comprehensive Cancer Center, University of Wisconsin, Madison, WI 53726, USA
    Epidemiology 19:417-23. 2008
    ..Recent studies have also considered potential health effects associated with exposure to environmental contaminants in breastmilk...
  38. pmc Prediagnostic use of hormone therapy and mortality after breast cancer
    Polly A Newcomb
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Cancer Epidemiol Biomarkers Prev 17:864-71. 2008
    ..Due to the high prevalence of past and current hormone use, it is important to investigate whether these preparations are related to breast cancer mortality...
  39. pmc Proportion of invasive breast cancer attributable to risk factors modifiable after menopause
    Brian L Sprague
    Department of Population Health Sciences, University of Wisconsin Madison, Madison, WI 53726, USA
    Am J Epidemiol 168:404-11. 2008
    ..3%. These findings suggest that a substantial fraction of postmenopausal breast cancer may be avoided by purposeful changes in lifestyle later in life...
  40. ncbi request reprint Association of NAT2 and smoking in relation to breast cancer incidence in a population-based case-control study (United States)
    Kathleen M Egan
    Division of General Internal Medicine and the Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN, 37232, USA
    Cancer Causes Control 14:43-51. 2003
    ..To evaluate the potential interaction between N-acetyltransferase 2 (NAT2) and smoking in breast cancer incidence...
  41. doi request reprint The association between in utero cigarette smoke exposure and age at menopause
    William C Strohsnitter
    Department of Obstetrics and Gynecology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am J Epidemiol 167:727-33. 2008
    ..The possibility that active cigarette smoking modifies this effect is also suggested...
  42. ncbi request reprint Occupational exposure to electromagnetic field and breast cancer risk in a large, population-based, case-control study in the United States
    Jane A McElroy
    University of Wisconsin Paul P Carbone Comprehensive Cancer Center, Madison, WI 53726, USA
    J Occup Environ Med 49:266-74. 2007
    ..Our objective was to evaluate women who were occupationally exposed to electromagnetic fields (EMF) and breast cancer risk...
  43. ncbi request reprint Lifetime recreational and occupational physical activity and risk of in situ and invasive breast cancer
    Brian L Sprague
    University of Wisconsin Paul P Carbone Comprehensive Cancer Center, Department of Population Health Sciences, University of Wisconsin Madison, Madison, Wisconsin 53726, USA
    Cancer Epidemiol Biomarkers Prev 16:236-43. 2007
    ..Lifetime strenuous occupational activity was not associated with invasive breast cancer risk. These results provide further evidence that, for most women, physical activity may reduce the risk of invasive breast cancer...
  44. ncbi request reprint Hypospadias in sons of women exposed to diethylstilbestrol in utero
    Julie R Palmer
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215, USA
    Epidemiology 16:583-6. 2005
    ..Dutch investigators have reported a 20-fold increase in risk of hypospadias among sons of women who were exposed to DES in utero. We assessed this relation in data from an ongoing study of DES-exposed persons...
  45. ncbi request reprint Conditions associated with antibodies against the tumor-associated antigen MUC1 and their relationship to risk for ovarian cancer
    Daniel W Cramer
    Epidemiology Center, Brigham and Women s Hospital, 221 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:1125-31. 2005
    ....
  46. ncbi request reprint Breast cancer incidence in women prenatally exposed to maternal cigarette smoke
    William C Strohsnitter
    Department of Obstetrics and Gynecology, Tufts New England Medical Center, 750 Washington Street, Boston, MA 02111, USA
    Epidemiology 16:342-5. 2005
    ..At the start of this study, cigarette smoking history was obtained directly from the mother...
  47. pmc Genetic variation in the progesterone receptor gene and ovarian cancer risk
    Kathryn L Terry
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Epidemiol 161:442-51. 2005
    ..76, 95% confidence interval: 0.62, 0.92). Associations were similar after stratifying by ovarian cancer histologies and risk factors...
  48. ncbi request reprint Risk of benign gynecologic tumors in relation to prenatal diethylstilbestrol exposure
    Lauren A Wise
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215, USA
    Obstet Gynecol 105:167-73. 2005
    ..To investigate the association between prenatal diethylstilbestrol (DES) exposure and risk of benign gynecologic tumors...
  49. ncbi request reprint STK15 polymorphism and breast cancer risk in a population-based study
    Kathleen M Egan
    Vanderbilt University Medical Center, Suite 6000, MCE, Nashville, TN 37232 8300, USA
    Carcinogenesis 25:2149-53. 2004
    ..79). No interaction was detected between STK15 variants and estrogenic risk factors, although the power of these analyses was limited. These results suggest that STK15 may represent a low penetrance type breast cancer susceptibility gene...
  50. ncbi request reprint MnSOD polymorphism and breast cancer in a population-based case-control study
    Kathleen M Egan
    Department of Medicine, Vanderbilt University Medical Center, Suite 6000 Medical Center East, Nashville, TN 37232 8300, USA
    Cancer Lett 199:27-33. 2003
    ..91-1.77) or two (RR: 1.18; 95% CI: 0.81-1.73) Ala alleles compared to those homozygous for the wild-type Val genotype. Results do not support any overall association of the Ala-9Val MnSOD polymorphism to the development of breast cancer...
  51. ncbi request reprint Interaction between CYP1A1 polymorphic variants and dietary exposures influencing ovarian cancer risk
    Kathryn L Terry
    Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 12:187-90. 2003
    ..Significant interaction may exist between polymorphic variants of CYP1A1 and caffeine that could explain weak or inconsistent associations between caffeine and ovarian cancer when genotype has not been considered...
  52. ncbi request reprint Early life risk factors in cancer: the relation of birth weight to adult obesity
    Nicole M Leong
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Int J Cancer 103:789-91. 2003
    ..76). These data suggest that both low and high birth weights are associated with higher adult BMI and support the hypothesis that fetal experience may influence adult obesity with potential consequences for risk of several major cancers...
  53. ncbi request reprint Risk of breast cancer in women exposed to diethylstilbestrol in utero: prelimiinary results (United States)
    Julie R Palmer
    Slone Epidemiology Unit, Boston University School of Medicine, MA 02215, USA
    Cancer Causes Control 13:753-8. 2002
    ..We evaluated the relation of in-utero DES exposure to the risk of adult breast cancer...
  54. ncbi request reprint Alteration of chromosome 9p21 and/or p16 in benign and dysplastic nevi suggests a role in early melanoma progression (United States)
    Tina P Tran
    Department of Anatomy, Virginia Commonwealth University, Richmond, USA
    Cancer Causes Control 13:675-82. 2002
    ..The goal of this work was to discover if p16/9p21 alterations occur early in precursor lesions as well as related sporadic melanomas...
  55. ncbi request reprint Risk of ovarian cancer in the United States in relation to anthropometric measures: does the association depend on menopausal status?
    Hannah Kuper
    International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, UK
    Cancer Causes Control 13:455-63. 2002
    ..To elucidate the association between anthropometric measures and ovarian cancer risk...
  56. ncbi request reprint Postmenopausal estrogen and progestin use in relation to breast cancer risk
    Polly A Newcomb
    University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin 53706, USA
    Cancer Epidemiol Biomarkers Prev 11:593-600. 2002
    ..09; 95% CI, 1.07-4.07 for ever use versus nonuse). Estrogen-progestin use, both sequential and continuous, appears to be more strongly associated with risk of breast cancer than use of estrogen alone...
  57. ncbi request reprint Duration of sleep and breast cancer risk in a large population-based case-control study
    Jane A McElroy
    University of Wisconsin Comprehensive Cancer Center, Madison, 53726, USA
    J Sleep Res 15:241-9. 2006
    ..In contrast, short duration of sleep (<7 h/night) is not substantially associated with increased risk. Further research in this area is warranted...
  58. ncbi request reprint From menarche to menopause: trends among US Women born from 1912 to 1969
    Hazel B Nichols
    University of Wisconsin Comprehensive Cancer Center, Madison, WI 53726, USA
    Am J Epidemiol 164:1003-11. 2006
    ..1 years among women born between 1915 and 1919 to 37.7 years among the 1935-1939 cohort (p = 0.0001). These findings have implications for women's lifetime exposure to circulating endogenous hormones...
  59. ncbi request reprint Prospective breast cancer risk prediction model for women undergoing screening mammography
    William E Barlow
    Cancer Research and Biostatistics, 1730 Minor Avenue, Suite 1900, Seattle, WA 98101, USA
    J Natl Cancer Inst 98:1204-14. 2006
    ..We used prospective risk information to predict a diagnosis of breast cancer in a cohort of 1 million women undergoing screening mammography...
  60. ncbi request reprint Prenatal diethylstilbestrol exposure and risk of breast cancer
    Julie R Palmer
    Slone Epidemiology Center, Boston University, 1010 Commonwealth Avenue, Boston, MA 02215, USA
    Cancer Epidemiol Biomarkers Prev 15:1509-14. 2006
    ..The findings support the hypothesis that prenatal hormone levels influence breast cancer risk...
  61. ncbi request reprint Genetic variation in tumor necrosis factor and lymphotoxin-alpha (TNF-LTA) and breast cancer risk
    Mia M Gaudet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Hum Genet 121:483-90. 2007
    ..Additional studies are required to replicate these findings and to determine whether rs361525 is a causative SNP or is a marker of a causative SNP...
  62. ncbi request reprint Age at natural menopause in women exposed to diethylstilbestrol in utero
    Elizabeth E Hatch
    Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA
    Am J Epidemiol 164:682-8. 2006
    ..Age at menopause has been related, albeit inconsistently, to several exposures, but, to the authors' knowledge, this is the first study to suggest that a prenatal exposure may influence reproductive lifespan...
  63. ncbi request reprint Genetic polymorphisms in base-excision repair pathway genes and risk of breast cancer
    Yawei Zhang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 15:353-8. 2006
    ..6; 95% CI, 1.1-2.4; P = 0.02). In conclusion, our results do not support that the polymorphisms evaluated in six BER pathway genes play a major role in breast carcinogenesis, particularly in Caucasian populations...
  64. ncbi request reprint Reproductive outcomes in men with prenatal exposure to diethylstilbestrol
    Kimberly M Perez
    Department of Social and Preventive Medicine, University of Buffalo, State of New York, Buffalo, New York, USA
    Fertil Steril 84:1649-56. 2005
    ..To examine prenatal diethylstilbestrol (DES) exposure in relation to male reproductive outcomes...
  65. ncbi request reprint Incessant ovulation, mucin 1 immunity, and risk for ovarian cancer
    Kathryn L Terry
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, 221 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:30-5. 2007
    ..In this study, we examined whether the total number of ovulatory cycles decreases the likelihood of anti-MUC1 antibodies and provides an immune basis for the association between "incessant ovulation" and ovarian cancer risk...
  66. pmc Androgen receptor cytosine, adenine, guanine repeats, and haplotypes in relation to ovarian cancer risk
    Kathryn L Terry
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Res 65:5974-81. 2005
    ..Our results suggest that possession of two long AR alleles (> or = 22 CAG repeats) may be associated with increased risk of ovarian cancer compared with women with two short AR alleles (<22 CAG repeats)...
  67. ncbi request reprint Whole-genome amplification of oral rinse self-collected DNA in a population-based case-control study of breast cancer
    Xueying Liang
    Center for Human Genetics Research and Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Cancer Epidemiol Biomarkers Prev 16:1610-4. 2007
    ..Whole-genome amplification may introduce substantial allele amplification bias in gDNA collected using a common protocol in population-based epidemiologic studies...
  68. ncbi request reprint Allele-specific loss of heterozygosity at the DAL-1/4.1B (EPB41L3) tumor-suppressor gene locus in the absence of mutation
    Kanokwan Kittiniyom
    David and Doreen Hermelin Laboratory of Molecular Oncogenetics, Hermelin Brain Tumor Center and Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Genes Chromosomes Cancer 40:190-203. 2004
    ..These studies indicate that mechanisms such as imprinting or monoallelic expression in combination with loss of heterozygosity may be responsible for loss of the DAL-1/4.1B protein in early breast disease...
  69. pmc Secondary sex ratio among women exposed to diethylstilbestrol in utero
    Lauren A Wise
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215, USA
    Environ Health Perspect 115:1314-9. 2007
    ..Previous studies have suggested an association between endocrine-disrupting compounds and secondary sex ratio...
  70. ncbi request reprint Polymorphisms in DNA double-strand break repair genes and risk of breast cancer: two population-based studies in USA and Poland, and meta-analyses
    Montserrat Garcia-Closas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Room 7076, Rockville, MD 20952 7234, USA
    Hum Genet 119:376-88. 2006
    ..Evaluation of potential underlying gene-gene interactions or associations in population subgroups will require even larger sample sizes...
  71. doi request reprint Physical activity and survival after diagnosis of invasive breast cancer
    Crystal N Holick
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Cancer Epidemiol Biomarkers Prev 17:379-86. 2008
    ..This study provides support for reduced overall mortality and mortality from breast cancer among women who engage in physical activity after breast cancer diagnosis...

Research Grants9

  1. ATYPICAL NEVI IN MELANOMA--A CASE-CONTROL STUDY
    Linda Titus Ernstoff; Fiscal Year: 1999
    ..The ability to self-diagnose atypical nevi has important implications for melanoma prevention. ..
  2. ATYPICAL NEVI IN MELANOMA--A CASE-CONTROL STUDY
    Linda Titus Ernstoff; Fiscal Year: 2000
    ..The ability to self-diagnose atypical nevi has important implications for melanoma prevention. ..
  3. ATYPICAL NEVI IN MELANOMA--A CASE-CONTROL STUDY
    Linda Titus Ernstoff; Fiscal Year: 2001
    ..The ability to self-diagnose atypical nevi has important implications for melanoma prevention. ..
  4. Melanoma Pathogenesis
    Linda Titus Ernstoff; Fiscal Year: 2004
    ..e., slide preparation) of pathology specimens, and the refinement of laboratory techniques for analyzing chromosome 9p21 alterations. ..
  5. Melanoma Pathogenesis
    Linda Titus Ernstoff; Fiscal Year: 2005
    ..e., slide preparation) of pathology specimens, and the refinement of laboratory techniques for analyzing chromosome 9p21 alterations. ..
  6. Melanoma Pathogenesis
    Linda Titus Ernstoff; Fiscal Year: 2006
    ..e., slide preparation) of pathology specimens, and the refinement of laboratory techniques for analyzing chromosome 9p21 alterations. ..