F Y Tanga

Summary

Affiliation: Dartmouth Medical School
Country: USA

Publications

  1. ncbi Attenuation of morphine tolerance, withdrawal-induced hyperalgesia, and associated spinal inflammatory immune responses by propentofylline in rats
    Vasudeva Raghavendra
    Department of Anesthesiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA
    Neuropsychopharmacology 29:327-34. 2004
  2. ncbi The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy
    Flobert Y Tanga
    Department of Anesthesiology, Dartmouth Medical School, Lebanon, NH 03756, USA
    Proc Natl Acad Sci U S A 102:5856-61. 2005
  3. ncbi Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain
    F Y Tanga
    Department of Anesthesiology, Dartmouth Hitchcock Medical Center, HB 7125, One Medical Center Drive, Lebanon, NH 03756, USA
    Neurochem Int 45:397-407. 2004
  4. ncbi The contributing role of CD14 in toll-like receptor 4 dependent neuropathic pain
    L Cao
    Department of Anesthesiology, HB 7125, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Neuroscience 158:896-903. 2009
  5. ncbi Role of astrocytic S100beta in behavioral hypersensitivity in rodent models of neuropathic pain
    F Y Tanga
    Department of Anesthesiology, Dartmouth Medical School, Lebanon, NH 03756, USA
    Neuroscience 140:1003-10. 2006
  6. ncbi Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesia
    Joyce A DeLeo
    Department of Anesthesiology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Neuroscientist 10:40-52. 2004
  7. ncbi Complete Freunds adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS
    Vasudeva Raghavendra
    Department of Anaesthesiology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Eur J Neurosci 20:467-73. 2004
  8. ncbi Differential spinal cord gene expression in rodent models of radicular and neuropathic pain
    Michael L LaCroix-Fralish
    Department of Pharmacology and Toxicology, Dartmouth College, Hanover, New Hampshire 03756, USA
    Anesthesiology 104:1283-92. 2006
  9. ncbi Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus
    Nilufer Esen
    Department of Neurobiology and Developmental Science, University of Arkansas for Medical Sciences, Little Rock 72205, USA
    J Neurochem 88:746-58. 2004

Detail Information

Publications9

  1. ncbi Attenuation of morphine tolerance, withdrawal-induced hyperalgesia, and associated spinal inflammatory immune responses by propentofylline in rats
    Vasudeva Raghavendra
    Department of Anesthesiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA
    Neuropsychopharmacology 29:327-34. 2004
    ..These results further support the hypothesis that spinal glia and proinflammatory cytokines contribute to the mechanisms of morphine tolerance and associated abnormal pain sensitivity...
  2. ncbi The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy
    Flobert Y Tanga
    Department of Anesthesiology, Dartmouth Medical School, Lebanon, NH 03756, USA
    Proc Natl Acad Sci U S A 102:5856-61. 2005
    ..Further understanding of this early, specific, innate CNS/microglial response and how it leads to sustained glial/neuronal hypersensitivity may point to new therapies for the prevention and treatment of neuropathic pain syndromes...
  3. ncbi Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain
    F Y Tanga
    Department of Anesthesiology, Dartmouth Hitchcock Medical Center, HB 7125, One Medical Center Drive, Lebanon, NH 03756, USA
    Neurochem Int 45:397-407. 2004
    ..In summary, these data demonstrate a distinct spinal glial response following nerve injury using real-time RT-PCR...
  4. ncbi The contributing role of CD14 in toll-like receptor 4 dependent neuropathic pain
    L Cao
    Department of Anesthesiology, HB 7125, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Neuroscience 158:896-903. 2009
    ..Together, these data demonstrate that CD14 plays a contributing role in TLR4-dependent nerve injury-induced neuropathic pain...
  5. ncbi Role of astrocytic S100beta in behavioral hypersensitivity in rodent models of neuropathic pain
    F Y Tanga
    Department of Anesthesiology, Dartmouth Medical School, Lebanon, NH 03756, USA
    Neuroscience 140:1003-10. 2006
    ..Together, these results from both series of experiments using a peripheral nerve injury model in two different species implicate the involvement of glial-derived S100beta in the pathophysiology of neuropathic pain...
  6. ncbi Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesia
    Joyce A DeLeo
    Department of Anesthesiology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Neuroscientist 10:40-52. 2004
    ..The challenge remains in the careful perturbation of injury/opioid-induced neuroimmune activation to down-regulate this process without inhibiting beneficial CNS autoimmunity that subserves neuronal protection following injury...
  7. ncbi Complete Freunds adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS
    Vasudeva Raghavendra
    Department of Anaesthesiology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Eur J Neurosci 20:467-73. 2004
    ..These findings further support a unifying theory that glial activation and enhanced cytokine expression at the CNS have a role in eliciting behavioral hypersensitivity...
  8. ncbi Differential spinal cord gene expression in rodent models of radicular and neuropathic pain
    Michael L LaCroix-Fralish
    Department of Pharmacology and Toxicology, Dartmouth College, Hanover, New Hampshire 03756, USA
    Anesthesiology 104:1283-92. 2006
    ..Furthermore, these distinct pathophysiologic mechanisms in neuropathic versus radicular pain may implicate unique drug therapies for these types of chronic pain syndromes...
  9. ncbi Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus
    Nilufer Esen
    Department of Neurobiology and Developmental Science, University of Arkansas for Medical Sciences, Little Rock 72205, USA
    J Neurochem 88:746-58. 2004
    ..These findings suggest that astrocytes may play a key role in the initial antibacterial immune response in the CNS through engagement of TLR2...