Agnieszka Swiatecka-Urban

Summary

Affiliation: Dartmouth Medical School
Country: USA

Publications

  1. ncbi Pseudomonas aeruginosa inhibits endocytic recycling of CFTR in polarized human airway epithelial cells
    Agnieszka Swiatecka-Urban
    Department of Physiology, Dartmouth Medical School, 1 Rope Ferry Road, HB 7701, Hanover, NH 03755, USA
    Am J Physiol Cell Physiol 290:C862-72. 2006
  2. ncbi Anti-interleukin-2 receptor antibodies for the prevention of rejection in pediatric renal transplant patients: current status
    Agnieszka Swiatecka-Urban
    Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    Paediatr Drugs 5:699-716. 2003
  3. ncbi Myosin VI regulates endocytosis of the cystic fibrosis transmembrane conductance regulator
    Agnieszka Swiatecka-Urban
    Dartmouth Medical School, Department of Physiology, Hanover, New Hampshire 03755, USA
    J Biol Chem 279:38025-31. 2004
  4. ncbi The short apical membrane half-life of rescued {Delta}F508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of {Delta}F508-CFTR in polarized human airway epithelial cells
    Agnieszka Swiatecka-Urban
    Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Biol Chem 280:36762-72. 2005
  5. pmc The DeltaF508-CFTR mutation results in increased biofilm formation by Pseudomonas aeruginosa by increasing iron availability
    Sophie Moreau-Marquis
    Department of Physiology, Dartmouth Medical School, Hanover, NH 03755, USA
    Am J Physiol Lung Cell Mol Physiol 295:L25-37. 2008
  6. ncbi Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells
    Agnieszka Swiatecka-Urban
    Department of Physiology, Dartmouth Medical School, Dartmouth College, Hanover, New Hampshire 03755, USA
    J Biol Chem 282:23725-36. 2007
  7. ncbi PDZ domain interaction controls the endocytic recycling of the cystic fibrosis transmembrane conductance regulator
    Agnieszka Swiatecka-Urban
    Dartmouth Medical School, Department of Physiology, Hanover, New Hampshire 03755, USA
    J Biol Chem 277:40099-105. 2002
  8. pmc c-Cbl facilitates endocytosis and lysosomal degradation of cystic fibrosis transmembrane conductance regulator in human airway epithelial cells
    Siying Ye
    Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Biol Chem 285:27008-18. 2010
  9. pmc The Pseudomonas aeruginosa secreted protein PA2934 decreases apical membrane expression of the cystic fibrosis transmembrane conductance regulator
    Daniel P Maceachran
    Department of Microbiology and Immunology, Dartmouth Medical School, Hanover, NH 03755, USA
    Infect Immun 75:3902-12. 2007
  10. ncbi Mizoribine corrects defective nephrin biogenesis by restoring intracellular energy balance
    Aya Nakajo
    Department of Pediatrics, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, Tokyo 181 8611, Japan
    J Am Soc Nephrol 18:2554-64. 2007

Collaborators

Detail Information

Publications11

  1. ncbi Pseudomonas aeruginosa inhibits endocytic recycling of CFTR in polarized human airway epithelial cells
    Agnieszka Swiatecka-Urban
    Department of Physiology, Dartmouth Medical School, 1 Rope Ferry Road, HB 7701, Hanover, NH 03755, USA
    Am J Physiol Cell Physiol 290:C862-72. 2006
    ..These data suggest that chronic infection with P. aeruginosa may interfere with therapeutic strategies aimed at increasing the apical membrane expression of DeltaF508-CFTR...
  2. ncbi Anti-interleukin-2 receptor antibodies for the prevention of rejection in pediatric renal transplant patients: current status
    Agnieszka Swiatecka-Urban
    Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    Paediatr Drugs 5:699-716. 2003
    ..This administration regimen maintains basiliximab levels necessary to completely saturate the IL-2Ralpha (>0.2 microg/mL) in children for at least 3 weeks...
  3. ncbi Myosin VI regulates endocytosis of the cystic fibrosis transmembrane conductance regulator
    Agnieszka Swiatecka-Urban
    Dartmouth Medical School, Department of Physiology, Hanover, New Hampshire 03755, USA
    J Biol Chem 279:38025-31. 2004
    ..CFTR endocytosis was decreased by cytochalasin D, an actin-filament depolymerizing agent. Taken together, these data indicate that myosin VI and Dab2 facilitate CFTR endocytosis by a mechanism that requires actin filaments...
  4. ncbi The short apical membrane half-life of rescued {Delta}F508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of {Delta}F508-CFTR in polarized human airway epithelial cells
    Agnieszka Swiatecka-Urban
    Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Biol Chem 280:36762-72. 2005
    ....
  5. pmc The DeltaF508-CFTR mutation results in increased biofilm formation by Pseudomonas aeruginosa by increasing iron availability
    Sophie Moreau-Marquis
    Department of Physiology, Dartmouth Medical School, Hanover, NH 03755, USA
    Am J Physiol Lung Cell Mol Physiol 295:L25-37. 2008
    ..aeruginosa biofilms with a dramatically increased antibiotic resistance. The DeltaF508-CFTR mutation enhances biofilm formation, in part, by increasing Fe release into the apical medium...
  6. ncbi Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells
    Agnieszka Swiatecka-Urban
    Department of Physiology, Dartmouth Medical School, Dartmouth College, Hanover, New Hampshire 03755, USA
    J Biol Chem 282:23725-36. 2007
    ..Taken together, these data indicate that myosin Vb is required for CFTR recycling in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells...
  7. ncbi PDZ domain interaction controls the endocytic recycling of the cystic fibrosis transmembrane conductance regulator
    Agnieszka Swiatecka-Urban
    Dartmouth Medical School, Department of Physiology, Hanover, New Hampshire 03755, USA
    J Biol Chem 277:40099-105. 2002
    ..Our results identify a new role for PDZ proteins in regulating the endocytic recycling of CFTR in polarized epithelial cells...
  8. pmc c-Cbl facilitates endocytosis and lysosomal degradation of cystic fibrosis transmembrane conductance regulator in human airway epithelial cells
    Siying Ye
    Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Biol Chem 285:27008-18. 2010
    ....
  9. pmc The Pseudomonas aeruginosa secreted protein PA2934 decreases apical membrane expression of the cystic fibrosis transmembrane conductance regulator
    Daniel P Maceachran
    Department of Microbiology and Immunology, Dartmouth Medical School, Hanover, NH 03755, USA
    Infect Immun 75:3902-12. 2007
    ..We propose a model in which the Cif-mediated decrease in apical membrane expression of CFTR by environmental isolates of P. aeruginosa facilitates the colonization of the CF lung by this microbe...
  10. ncbi Mizoribine corrects defective nephrin biogenesis by restoring intracellular energy balance
    Aya Nakajo
    Department of Pediatrics, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, Tokyo 181 8611, Japan
    J Am Soc Nephrol 18:2554-64. 2007
    ..Further understanding of the ER microenvironment may lead to novel approaches to treat diseases in which abnormal handling of proteins plays a role in pathogenesis...
  11. ncbi Activation of mitochondrial apoptotic pathways in human renal allografts after ischemiareperfusion injury
    M Patricia Castaneda
    Division of Nephrology, Children s Hospital at Montefiore, Bronx, New York, USA
    Transplantation 76:50-4. 2003
    ..We tested the hypothesis that activation of specific apoptotic pathways represents a mechanism for tubular cell death after CAD kidney transplantation...