Harold Swartz

Summary

Affiliation: Dartmouth Medical School
Country: USA

Publications

  1. doi request reprint Clinical EPR: Unique Opportunities and Some Challenges
    Harold M Swartz
    Department of Radiology, Geisel School of Medicine at Dartmouth, Dartmouth College, 48 Lafayette Street, Lebanon, NH 03766 Electronic address
    Acad Radiol 21:197-206. 2014
  2. pmc Electron paramagnetic resonance dosimetry for a large-scale radiation incident
    Harold M Swartz
    Dartmouth Medical School, Hanover, NH 03755, USA
    Health Phys 103:255-67. 2012
  3. ncbi request reprint Seeing is believing--visualizing drug delivery in vitro and in vivo
    Harold Swartz
    Hinman Box 7785, 702 Vail Building, Dartmouth Medical School, Hanover, NH 03755 3863, USA
    Adv Drug Deliv Rev 57:1085-6. 2005
  4. doi request reprint A critical assessment of biodosimetry methods for large-scale incidents
    Harold M Swartz
    The EPR Center for Viable Systems, Dartmouth Medical School, Hanover, NH 03755, USA
    Health Phys 98:95-108. 2010
  5. pmc Oxygen consumption rates and oxygen concentration in molt-4 cells and their mtDNA depleted (rho0) mutants
    Jiangang Shen
    EPR Center, Department of Diagnostic Radiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    Biophys J 84:1291-8. 2003
  6. pmc Repeated assessment of orthotopic glioma pO(2) by multi-site EPR oximetry: a technique with the potential to guide therapeutic optimization by repeated measurements of oxygen
    Nadeem Khan
    EPR Center for the Study of Viable Systems, Dartmouth Medical School, Hanover, NH 03755, USA
    J Neurosci Methods 204:111-7. 2012
  7. pmc Dynamic changes in oxygenation of intracranial tumor and contralateral brain during tumor growth and carbogen breathing: a multisite EPR oximetry with implantable resonators
    Huagang Hou
    EPR Center for the Study of Viable Systems, Department of Radiology, Dartmouth Medical School, Hanover, NH 03755, United States
    J Magn Reson 214:22-8. 2012
  8. pmc Repeated tumor oximetry to identify therapeutic window during metronomic cyclophosphamide treatment of 9L gliomas
    Sriram Mupparaju
    EPR Center for Viable Systems, Dartmouth Medical School, Hanover, NH 03755, USA
    Oncol Rep 26:281-6. 2011
  9. pmc Effect of a topical vasodilator on tumor hypoxia and tumor oxygen guided radiotherapy using EPR oximetry
    Huagang Hou
    EPR Center for Viable Systems, Department of Diagnostic Radiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    Radiat Res 173:651-8. 2010
  10. pmc Repeated tumor pO(2) measurements by multi-site EPR oximetry as a prognostic marker for enhanced therapeutic efficacy of fractionated radiotherapy
    Huagang Hou
    Department of Diagnostic Radiology, Dartmouth Medical School, Hanover, NH, USA
    Radiother Oncol 91:126-31. 2009

Detail Information

Publications14

  1. doi request reprint Clinical EPR: Unique Opportunities and Some Challenges
    Harold M Swartz
    Department of Radiology, Geisel School of Medicine at Dartmouth, Dartmouth College, 48 Lafayette Street, Lebanon, NH 03766 Electronic address
    Acad Radiol 21:197-206. 2014
    ..Further work is in progress to translate this unique technology to routine clinical practice. ..
  2. pmc Electron paramagnetic resonance dosimetry for a large-scale radiation incident
    Harold M Swartz
    Dartmouth Medical School, Hanover, NH 03755, USA
    Health Phys 103:255-67. 2012
    ..The authors conclude that electron paramagnetic resonance dosimetry is likely to be a useful part of triage for a large-scale radiation incident...
  3. ncbi request reprint Seeing is believing--visualizing drug delivery in vitro and in vivo
    Harold Swartz
    Hinman Box 7785, 702 Vail Building, Dartmouth Medical School, Hanover, NH 03755 3863, USA
    Adv Drug Deliv Rev 57:1085-6. 2005
    ..This issue of ADDR features novel, non-radioactive methods potentially useful for drug delivery scientists in selecting the most appropriate imaging techniques for solving the drug delivery problem at hand...
  4. doi request reprint A critical assessment of biodosimetry methods for large-scale incidents
    Harold M Swartz
    The EPR Center for Viable Systems, Dartmouth Medical School, Hanover, NH 03755, USA
    Health Phys 98:95-108. 2010
    ..In conclusion, biodosimetry techniques have different properties, and knowledge of their properties for meeting the different needs for different stages will result in their most effective use in a nuclear disaster mass-casualty event...
  5. pmc Oxygen consumption rates and oxygen concentration in molt-4 cells and their mtDNA depleted (rho0) mutants
    Jiangang Shen
    EPR Center, Department of Diagnostic Radiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    Biophys J 84:1291-8. 2003
    ..The results are consistent with our earlier findings suggesting that such oxygen gradients may be a general phenomenon found in most or all cell systems under appropriate conditions...
  6. pmc Repeated assessment of orthotopic glioma pO(2) by multi-site EPR oximetry: a technique with the potential to guide therapeutic optimization by repeated measurements of oxygen
    Nadeem Khan
    EPR Center for the Study of Viable Systems, Dartmouth Medical School, Hanover, NH 03755, USA
    J Neurosci Methods 204:111-7. 2012
    ..Furthermore, EPR oximetry could be potentially used to enhance the outcome of chemoradiation by scheduling treatments at times of increase in glioma pO(2)...
  7. pmc Dynamic changes in oxygenation of intracranial tumor and contralateral brain during tumor growth and carbogen breathing: a multisite EPR oximetry with implantable resonators
    Huagang Hou
    EPR Center for the Study of Viable Systems, Department of Radiology, Dartmouth Medical School, Hanover, NH 03755, United States
    J Magn Reson 214:22-8. 2012
    ..We report a recently developed electron paramagnetic resonance (EPR) oximetry approach with multiple probe implantable resonators (IRs) that allow repeated measurements of oxygen in tissue at depths of greater than 10mm...
  8. pmc Repeated tumor oximetry to identify therapeutic window during metronomic cyclophosphamide treatment of 9L gliomas
    Sriram Mupparaju
    EPR Center for Viable Systems, Dartmouth Medical School, Hanover, NH 03755, USA
    Oncol Rep 26:281-6. 2011
    ..This vital information could also be used to schedule radiotherapy to enhance therapeutic outcome...
  9. pmc Effect of a topical vasodilator on tumor hypoxia and tumor oxygen guided radiotherapy using EPR oximetry
    Huagang Hou
    EPR Center for Viable Systems, Department of Diagnostic Radiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    Radiat Res 173:651-8. 2010
    ..5% BN formulation led to a significant growth inhibition. EPR oximetry provided dynamic information on the changes in tumor pO(2), which could be used to identify responders and non-responders and schedule therapy during the experiments...
  10. pmc Repeated tumor pO(2) measurements by multi-site EPR oximetry as a prognostic marker for enhanced therapeutic efficacy of fractionated radiotherapy
    Huagang Hou
    Department of Diagnostic Radiology, Dartmouth Medical School, Hanover, NH, USA
    Radiother Oncol 91:126-31. 2009
    ..To investigate the temporal effects of single or fractionated radiotherapy on subcutaneous RIF-1 tumor pO(2) and to determine the therapeutic outcomes when the timing of fractionations is guided by tumor pO(2)...
  11. doi request reprint Cerebral oxygenation of the cortex and striatum following normobaric hyperoxia and mild hypoxia in rats by EPR oximetry using multi-probe implantable resonators
    Huagang Hou
    EPR Center for Viable Systems, Department of Diagnostic Radiology, Dartmouth Medical School, Hanover, NH 03755, USA
    Adv Exp Med Biol 701:61-7. 2011
    ..In addition, the ability to simultaneously measure the pO(2) in several areas of the brain provides important information that could potentially help differentiate the pO(2) changes that can occur due to global or local mechanisms...
  12. ncbi request reprint Plasma membrane cholesterol: a possible barrier to intracellular oxygen in normal and mutant CHO cells defective in cholesterol metabolism
    Nadeem Khan
    Department of Diagnostic Radiology, EPR Center, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    Biochemistry 42:23-9. 2003
    ..The results indicate that the concentration of cholesterol in the plasma membrane can be an important factor for the magnitude of the oxygen gradient observed across the cell membrane...
  13. ncbi request reprint Tumor PO(2) changes during photodynamic therapy depend upon photosensitizer type and time after injection
    Brian W Pogue
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    Comp Biochem Physiol A Mol Integr Physiol 132:177-84. 2002
    ....
  14. ncbi request reprint Measurements in vivo of parameters pertinent to ROS/RNS using EPR spectroscopy
    Nadeem Khan
    EPR Center, Department of Diagnostic Radiology, Dartmouth Medical School, Hanover, NH 03755, USA
    Mol Cell Biochem 234:341-57. 2002
    ..The current state of the art for these and other measurements is discussed, especially in relationship to experiments that are likely to be useful for studies of reactive oxygen species (ROS) and/or reactive nitrogen species (RNS)...