BRIAN WILLIAM POGUE

Summary

Affiliation: Dartmouth Medical School
Country: USA

Publications

  1. pmc Dark-field scanning in situ spectroscopy platform for broadband imaging of resected tissue
    Venkataramanan Krishnaswamy
    Thayer School of Engineering, 8000 Cummings Hall, Dartmouth College, Hanover, New Hampshire 03755, USA
    Opt Lett 36:1911-3. 2011
  2. ncbi request reprint Contrast-detail analysis for detection and characterization with near-infrared diffuse tomography
    B W Pogue
    Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA
    Med Phys 27:2693-700. 2000
  3. ncbi request reprint In vivo NADH fluorescence monitoring as an assay for cellular damage in photodynamic therapy
    B W Pogue
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    Photochem Photobiol 74:817-24. 2001
  4. ncbi request reprint Analysis of acetic acid-induced whitening of high-grade squamous intraepithelial lesions
    B W Pogue
    Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA
    J Biomed Opt 6:397-403. 2001
  5. ncbi request reprint Analysis of the heterogeneity of pO2 dynamics during photodynamic therapy with verteporfin
    B W Pogue
    Thayer School of Engineering, 8000 Cummings Hall, Dartmouth College, Hanover, NH 03755, USA
    Photochem Photobiol 74:700-6. 2001
  6. ncbi request reprint Calibration of near-infrared frequency-domain tissue spectroscopy for absolute absorption coefficient quantitation in neonatal head-simulating phantoms
    B W Pogue
    Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA
    J Biomed Opt 5:185-93. 2000
  7. ncbi request reprint Image analysis for discrimination of cervical neoplasia
    B W Pogue
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    J Biomed Opt 5:72-82. 2000
  8. ncbi request reprint Microwave image reconstruction utilizing log-magnitude and unwrapped phase to improve high-contrast object recovery
    P M Meaney
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    IEEE Trans Med Imaging 20:104-16. 2001
  9. ncbi request reprint Quantitative hemoglobin tomography with diffuse near-infrared spectroscopy: pilot results in the breast
    B W Pogue
    Thayer School of Engineering, Dartmouth College, 8000 Cummings Hall, Hanover, NH 03755-8000, USA
    Radiology 218:261-6. 2001
  10. pmc Monitoring of hemodynamic changes induced in the healthy breast through inspired gas stimuli with MR-guided diffuse optical imaging
    C M Carpenter
    Thayer School of Engineering, Dartmouth College, Hanover New Hampshire 03755, USA
    Med Phys 37:1638-46. 2010

Research Grants

  1. Micro CT/NIR Molecular Imaging of Cancer
    BRIAN WILLIAM POGUE; Fiscal Year: 2010
  2. Fluorescence Imaging to Optimize Cancer Therapy
    Brian Pogue; Fiscal Year: 2009
  3. Fluorescence Imaging to Optimize Cancer Therapy
    Brian Pogue; Fiscal Year: 2007
  4. OXYGEN DOSIMETRY IN PHOTODYNAMIC THERAPY
    Brian Pogue; Fiscal Year: 2001
  5. NIRFAST
    BRIAN WILLIAM POGUE; Fiscal Year: 2010

Detail Information

Publications12

  1. pmc Dark-field scanning in situ spectroscopy platform for broadband imaging of resected tissue
    Venkataramanan Krishnaswamy
    Thayer School of Engineering, 8000 Cummings Hall, Dartmouth College, Hanover, New Hampshire 03755, USA
    Opt Lett 36:1911-3. 2011
    ..The polychromatic raster scan design allows the rapid scanning necessary for use in surgical/clinical applications where timely decisions are required about tissue pathology...
  2. ncbi request reprint Contrast-detail analysis for detection and characterization with near-infrared diffuse tomography
    B W Pogue
    Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA
    Med Phys 27:2693-700. 2000
    ..This analysis provides an objective method for assessing detection and characterization limits and can be applied to future improvements in hardware system architecture as well as reconstruction algorithms...
  3. ncbi request reprint In vivo NADH fluorescence monitoring as an assay for cellular damage in photodynamic therapy
    B W Pogue
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    Photochem Photobiol 74:817-24. 2001
    ..This signal was monotonically correlated to the deposited dose used here and could provide a direct dosimetric measure of PDT-induced cellular death in the tissue being treated...
  4. ncbi request reprint Analysis of acetic acid-induced whitening of high-grade squamous intraepithelial lesions
    B W Pogue
    Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA
    J Biomed Opt 6:397-403. 2001
    ..This imaging and data normalization procedure may be applied to cervical lesions of different grades, to determine if a quantitative estimate provides predictive value during the colposcopic diagnosis...
  5. ncbi request reprint Analysis of the heterogeneity of pO2 dynamics during photodynamic therapy with verteporfin
    B W Pogue
    Thayer School of Engineering, 8000 Cummings Hall, Dartmouth College, Hanover, NH 03755, USA
    Photochem Photobiol 74:700-6. 2001
    ..The results suggest that hypoxic or poorly perfused vessels may be more susceptible to acute stasis than normoxic vessels in this treatment protocol...
  6. ncbi request reprint Calibration of near-infrared frequency-domain tissue spectroscopy for absolute absorption coefficient quantitation in neonatal head-simulating phantoms
    B W Pogue
    Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA
    J Biomed Opt 5:185-93. 2000
    ....
  7. ncbi request reprint Image analysis for discrimination of cervical neoplasia
    B W Pogue
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    J Biomed Opt 5:72-82. 2000
    ..Further research in this field can lead to advances in computer-aided diagnosis as well as the potential for online image enhancement in digital colposcopy...
  8. ncbi request reprint Microwave image reconstruction utilizing log-magnitude and unwrapped phase to improve high-contrast object recovery
    P M Meaney
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    IEEE Trans Med Imaging 20:104-16. 2001
    ..In these cases, the new algorithm recovers high-quality images without resorting to the use of a priori information on object contrast and/or size as previously required...
  9. ncbi request reprint Quantitative hemoglobin tomography with diffuse near-infrared spectroscopy: pilot results in the breast
    B W Pogue
    Thayer School of Engineering, Dartmouth College, 8000 Cummings Hall, Hanover, NH 03755-8000, USA
    Radiology 218:261-6. 2001
    ..Hemoglobin concentration appears to correlate with tumor vascularity without the need for exogenous contrast material and thereby has intrinsic diagnostic value...
  10. pmc Monitoring of hemodynamic changes induced in the healthy breast through inspired gas stimuli with MR-guided diffuse optical imaging
    C M Carpenter
    Thayer School of Engineering, Dartmouth College, Hanover New Hampshire 03755, USA
    Med Phys 37:1638-46. 2010
    ....
  11. ncbi request reprint Estimation of oxygen distribution in RIF-1 tumors by diffusion model-based interpretation of pimonidazole hypoxia and eppendorf measurements
    B W Pogue
    Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755
    Radiat Res 155:15-25. 2001
    ..This numerical method for oxygen capillary simulation is readily adaptable to histology sections and provides a method to examine the heterogeneity of oxygen within the capillaries and throughout the tumor tissue section being examined...
  12. ncbi request reprint Interstitial fluid pressure in soft tissue as a result of an externally applied contact pressure
    A L Darling
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    Phys Med Biol 52:4121-36. 2007
    ..The conclusion was that external contact forces can generate potentially clinically useful fluid pressure magnitudes in regions of sharp effective elastic modulus gradients, such as tumor boundaries...

Research Grants13

  1. Micro CT/NIR Molecular Imaging of Cancer
    BRIAN WILLIAM POGUE; Fiscal Year: 2010
    ....
  2. Fluorescence Imaging to Optimize Cancer Therapy
    Brian Pogue; Fiscal Year: 2009
    ..Both can be quantified in the same tissue by appropriate filtering and sequencing of the light signals, and this combined imaging approach will be examined for reliability of monitoring vascular versus cellular damage in vivo. ..
  3. Fluorescence Imaging to Optimize Cancer Therapy
    Brian Pogue; Fiscal Year: 2007
    ..Both can be quantified in the same tissue by appropriate filtering and sequencing of the light signals, and this combined imaging approach will be examined for reliability of monitoring vascular versus cellular damage in vivo. ..
  4. OXYGEN DOSIMETRY IN PHOTODYNAMIC THERAPY
    Brian Pogue; Fiscal Year: 2001
    ..abstract_text> ..
  5. NIRFAST
    BRIAN WILLIAM POGUE; Fiscal Year: 2010
    ..The project will develop this, and allow multicenter collaboration on a study to show that it can be integrated into existing Magnetic resonance imaging systems. ..