Javier Ochoa-Repáraz

Summary

Affiliation: Dartmouth Medical School
Country: USA

Publications

  1. doi request reprint Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression
    Javier Ochoa-Repáraz
    Section of Neurology, Department of Medicine, Dartmouth Medical School, Lebanon, NH 03756, USA
    J Immunol 185:4101-8. 2010
  2. doi request reprint Glatiramer acetate biases dendritic cells towards an anti-inflammatory phenotype by modulating OPN, IL-17, and RORγt responses and by increasing IL-10 production in experimental allergic encephalomyelitis
    Sakhina Begum-Haque
    Department of Neurology, Geisel Medical School at Dartmouth, Lebanon, NH 03756, USA
    J Neuroimmunol 254:117-24. 2013
  3. pmc Augmentation of regulatory B cell activity in experimental allergic encephalomyelitis by glatiramer acetate
    Sakhina Begum-Haque
    Department of Medicine, Dartmouth Medical School, Lebanon, NH 03756 Multiple Sclerosis Center Dartmouth College, Hanover, NH 03755, USA
    J Neuroimmunol 232:136-44. 2011
  4. doi request reprint Role of gut commensal microflora in the development of experimental autoimmune encephalomyelitis
    Javier Ochoa-Repáraz
    Department of Medicine, Dartmouth Medical School, Lebanon, NH 03756, USA
    J Immunol 183:6041-50. 2009
  5. doi request reprint Gut, bugs, and brain: role of commensal bacteria in the control of central nervous system disease
    Javier Ochoa-Repáraz
    Department of Neurology, Dartmouth Medical School, Lebanon, NH, USA
    Ann Neurol 69:240-7. 2011
  6. doi request reprint Increased expression of B cell-associated regulatory cytokines by glatiramer acetate in mice with experimental autoimmune encephalomyelitis
    Sakhina Begum-Haque
    Department of Medicine, Dartmouth Medical School, Lebanon, NH 03756, USA Multiple Sclerosis Center at Dartmouth College, Lebanon, NH 03756, USA
    J Neuroimmunol 219:47-53. 2010

Collaborators

  • Azizul Haque
  • Yan Wang
  • Sakhina Begum-Haque
  • Lloyd H Kasper
  • Marc Christy
  • Daniel Mielcarz
  • Javier Ochoa-Repáraz
  • Eli Kasper
  • Jacqueline Y Smith
  • Elizabeth C Nowak
  • Tim Lentini
  • Lauren E Ditrio
  • Islam F Fayed
  • Daniel W Mielcarz
  • Suryasarathi Dasgupta
  • Dennis L Kasper
  • Ashley R Burroughs
  • Alok Sharma

Detail Information

Publications6

  1. doi request reprint Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression
    Javier Ochoa-Repáraz
    Section of Neurology, Department of Medicine, Dartmouth Medical School, Lebanon, NH 03756, USA
    J Immunol 185:4101-8. 2010
    ..Our results suggest an important role for commensal bacterial Ags, in particular B. fragilis expressing polysaccharide A, in protecting against CNS demyelination in EAE and perhaps human multiple sclerosis...
  2. doi request reprint Glatiramer acetate biases dendritic cells towards an anti-inflammatory phenotype by modulating OPN, IL-17, and RORγt responses and by increasing IL-10 production in experimental allergic encephalomyelitis
    Sakhina Begum-Haque
    Department of Neurology, Geisel Medical School at Dartmouth, Lebanon, NH 03756, USA
    J Neuroimmunol 254:117-24. 2013
    ..Thus GA not only biases dendritic cells towards an anti-inflammatory phenotype, but also suppresses the expression of factors that affect the blood-brain barrier penetration during neuroinflammation...
  3. pmc Augmentation of regulatory B cell activity in experimental allergic encephalomyelitis by glatiramer acetate
    Sakhina Begum-Haque
    Department of Medicine, Dartmouth Medical School, Lebanon, NH 03756 Multiple Sclerosis Center Dartmouth College, Hanover, NH 03755, USA
    J Neuroimmunol 232:136-44. 2011
    ..Thus B cells can protect against EAE, and GA augments this effect in maintaining immune homeostasis and controlling EAE disease progression...
  4. doi request reprint Role of gut commensal microflora in the development of experimental autoimmune encephalomyelitis
    Javier Ochoa-Repáraz
    Department of Medicine, Dartmouth Medical School, Lebanon, NH 03756, USA
    J Immunol 183:6041-50. 2009
    ..This approach may offer a new therapeutic paradigm in the treatment of multiple sclerosis and perhaps other autoimmune conditions...
  5. doi request reprint Gut, bugs, and brain: role of commensal bacteria in the control of central nervous system disease
    Javier Ochoa-Repáraz
    Department of Neurology, Dartmouth Medical School, Lebanon, NH, USA
    Ann Neurol 69:240-7. 2011
    ..In contrast, other commensal bacteria and their antigenic products, when presented in the correct context, can protect against inflammation within the CNS...
  6. doi request reprint Increased expression of B cell-associated regulatory cytokines by glatiramer acetate in mice with experimental autoimmune encephalomyelitis
    Sakhina Begum-Haque
    Department of Medicine, Dartmouth Medical School, Lebanon, NH 03756, USA Multiple Sclerosis Center at Dartmouth College, Lebanon, NH 03756, USA
    J Neuroimmunol 219:47-53. 2010
    ..Thus, GA impacts both B cell survival and B cell cytokine production during CNS inflammatory disease in an EAE model...