Donald S Likosky

Summary

Affiliation: Dartmouth Medical School
Country: USA

Publications

  1. ncbi An epidemiologist's review of the case for pulsatile flow during cardiopulmonary bypass
    Donald S Likosky
    The Dartmouth Institute for Health Policy and Clinical Practice, Hanover, New Hampshire, USA
    J Extra Corpor Technol 41:P30-2. 2009
  2. doi Long-term survival of the very elderly undergoing coronary artery bypass grafting
    Donald S Likosky
    Department of Surgery, Dartmouth Medical School, Hanover, New Hampshire 03756, USA
    Ann Thorac Surg 85:1233-7. 2008
  3. ncbi Optimizing multi-center perfusion data
    Donald S Likosky
    The Dartmouth Institute for Health Policy and Clinical Practice, Hanover, New Hampshire, USA
    J Extra Corpor Technol 41:P7-10. 2009
  4. ncbi Forming a research question from a multi-center database
    Donald S Likosky
    The Dartmouth Institute for Health Policy and Clinical Practice, Hanover, New Hampshire, USA
    J Extra Corpor Technol 41:P33-6. 2009
  5. doi Long-term survival of the very elderly undergoing aortic valve surgery
    Donald S Likosky
    Department of Surgery, Dartmouth Hitchcock Medical Center, Hanover, NH, USA
    Circulation 120:S127-33. 2009
  6. ncbi Embolic activity subsequent to injection of the internal mammary artery with papaverine hydrochloride
    Donald S Likosky
    Department of Surgery and Community and Family Medicine and Medicine, Dartmouth Medical School, Hanover, NH 03756, USA
    Heart Surg Forum 8:E434-6. 2005
  7. doi Effect of prior cardiac operations on survival after coronary artery bypass grafting
    Donald S Likosky
    Department of Medicine, Dartmouth College, Hanover, NH, USA
    Ann Thorac Surg 92:1260-7. 2011
  8. ncbi Determination of etiologic mechanisms of strokes secondary to coronary artery bypass graft surgery
    Donald S Likosky
    Department of Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Stroke 34:2830-4. 2003
  9. ncbi Variability in surgeons' perioperative practices may influence the incidence of low-output failure after coronary artery bypass grafting surgery
    Donald S Likosky
    Departments of Medicine, Surgery, and Community and Family Medicine, and The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    Circ Cardiovasc Qual Outcomes 5:638-44. 2012
  10. ncbi Development and validation of a prediction model for strokes after coronary artery bypass grafting
    David C Charlesworth
    Department of Surgery, Catholic Medical Center, Manchester, New Hampshire 03102, USA
    Ann Thorac Surg 76:436-43. 2003

Research Grants

Detail Information

Publications52

  1. ncbi An epidemiologist's review of the case for pulsatile flow during cardiopulmonary bypass
    Donald S Likosky
    The Dartmouth Institute for Health Policy and Clinical Practice, Hanover, New Hampshire, USA
    J Extra Corpor Technol 41:P30-2. 2009
    ..However, there are inherent flaws in many of these. In this manuscript, I shall focus my attention on statistical power and sample size as it relates to the evidence base for pulsatile flow during cardiopulmonary bypass...
  2. doi Long-term survival of the very elderly undergoing coronary artery bypass grafting
    Donald S Likosky
    Department of Surgery, Dartmouth Medical School, Hanover, New Hampshire 03756, USA
    Ann Thorac Surg 85:1233-7. 2008
    ..Increasing numbers of the very elderly are undergoing coronary artery bypass graft surgery (CABG). Short-term results have been studied, but few data are available concerning long-term outcomes...
  3. ncbi Optimizing multi-center perfusion data
    Donald S Likosky
    The Dartmouth Institute for Health Policy and Clinical Practice, Hanover, New Hampshire, USA
    J Extra Corpor Technol 41:P7-10. 2009
    ..This manuscript addresses the following principles: the quality of the datasets, the use of the data to inform practice, and developing and maintaining social capital...
  4. ncbi Forming a research question from a multi-center database
    Donald S Likosky
    The Dartmouth Institute for Health Policy and Clinical Practice, Hanover, New Hampshire, USA
    J Extra Corpor Technol 41:P33-6. 2009
    ..Herein, some principles for formulating (successfully) a question from a multi-center database will be described...
  5. doi Long-term survival of the very elderly undergoing aortic valve surgery
    Donald S Likosky
    Department of Surgery, Dartmouth Hitchcock Medical Center, Hanover, NH, USA
    Circulation 120:S127-33. 2009
    ..Increasing numbers of the very elderly are undergoing aortic valve procedures. We describe the short- and long-term survivorship for this cohort...
  6. ncbi Embolic activity subsequent to injection of the internal mammary artery with papaverine hydrochloride
    Donald S Likosky
    Department of Surgery and Community and Family Medicine and Medicine, Dartmouth Medical School, Hanover, NH 03756, USA
    Heart Surg Forum 8:E434-6. 2005
    ..In this present study, we report an association between variations in the treatment of the internal mammary artery with the detection of cerebral embolic signals...
  7. doi Effect of prior cardiac operations on survival after coronary artery bypass grafting
    Donald S Likosky
    Department of Medicine, Dartmouth College, Hanover, NH, USA
    Ann Thorac Surg 92:1260-7. 2011
    ..We examined a recent regional experience to determine the effect of a prior cardiac operation on short-term and midterm outcomes after coronary artery bypass grafting (CABG)...
  8. ncbi Determination of etiologic mechanisms of strokes secondary to coronary artery bypass graft surgery
    Donald S Likosky
    Department of Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Stroke 34:2830-4. 2003
    ..We developed and implemented a classification system to identify the distribution and timing of stroke subtypes...
  9. ncbi Variability in surgeons' perioperative practices may influence the incidence of low-output failure after coronary artery bypass grafting surgery
    Donald S Likosky
    Departments of Medicine, Surgery, and Community and Family Medicine, and The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    Circ Cardiovasc Qual Outcomes 5:638-44. 2012
    ..We sought to understand which pre- and intra-operative factors contribute to postoperative LOF and to what degree the surgeon may influence rates of LOF...
  10. ncbi Development and validation of a prediction model for strokes after coronary artery bypass grafting
    David C Charlesworth
    Department of Surgery, Catholic Medical Center, Manchester, New Hampshire 03102, USA
    Ann Thorac Surg 76:436-43. 2003
    ..A preoperative risk prediction model was developed and validated based on regionally collected data...
  11. doi Factors associated with amputation or graft occlusion one year after lower extremity bypass in northern New England
    Philip P Goodney
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03765, USA
    Ann Vasc Surg 24:57-68. 2010
    ..Therefore, we examined risk factors that predict amputation or graft occlusion within the first year following lower extremity bypass...
  12. ncbi Intra- and postoperative predictors of stroke after coronary artery bypass grafting
    Donald S Likosky
    Department of Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Ann Thorac Surg 76:428-34; discussion 435. 2003
    ..We developed a risk prediction model for stroke based on factors in intra- and postoperative care, after adjusting for a patient's preoperative risk...
  13. doi Factors associated with death 1 year after lower extremity bypass in Northern New England
    Philip P Goodney
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebano, NH 03765, USA
    J Vasc Surg 51:71-8. 2010
    ..Therefore, we examined preoperative, patient-level risk factors that predict survival within the first year following LEB...
  14. doi Impact of preoperative left ventricular ejection fraction on long-term survival after aortic valve replacement for aortic stenosis
    Joshua B Goldberg
    Departments of Medicine, Surgery, and Community and Family Medicine, The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Hitchcock Medical Center, Hanover, NH 03756, USA
    Circ Cardiovasc Qual Outcomes 6:35-41. 2013
    ..The survival of patients who undergo aortic valve replacement (AVR) for severe aortic stenosis with reduced preoperative ejection fractions (EFs) is not well described in the literature...
  15. doi Limited blood transfusion does not impact survival in octogenarians undergoing cardiac operations
    James J Yun
    Department of Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
    Ann Thorac Surg 94:2038-45. 2012
    ..We previously reported that transfusion of 1 to 2 units of red blood cells (RBCs) confers a 16% increased hazard of late death after cardiac surgical treatment. We explored whether a similar effect existed among octogenarians...
  16. ncbi Intraoperative and postoperative variables associated with strokes following cardiac surgery
    Donald S Likosky
    Department of Medicine, Dartmouth Hitchcock Medical Center, Hanover, New Hampshire 03756, USA
    Heart Surg Forum 7:E271-6. 2004
    ..In the present study, we quantified the association between intraoperative and postoperative variables and stroke mechanisms while adjusting for patient and disease characteristics...
  17. ncbi Intraoperative red blood cell transfusion during coronary artery bypass graft surgery increases the risk of postoperative low-output heart failure
    Stephen D Surgenor
    Dartmouth Hitchcock Medical Center, 1 Medical Center Dr, Lebanon, NH 03756
    Circulation 114:I43-8. 2006
    ..The impact of intraoperative red blood cell (RBC) transfusion to treat anemia during surgery is less understood. We examined the relationship between anemia during CPB, RBC transfusion, and risk of low-output heart failure (LOF)...
  18. pmc Regional use of combined carotid endarterectomy/coronary artery bypass graft and the effect of patient risk
    Douglas W Jones
    Department of Surgery, New York Presbyterian Hospital, Weill Cornell Medical Center, New York, NY 10065, USA
    J Vasc Surg 56:668-76. 2012
    ..We studied the use of CEA/CABG in New England and compared indications and outcomes, including stratification by risk, symptoms, and performing center...
  19. doi The association of perioperative red blood cell transfusions and decreased long-term survival after cardiac surgery
    Stephen D Surgenor
    Dartmouth Hitchcock Medical Center, Department of Surgery, 1 Medical Center Drive Lebanon, NH 03756, USA
    Anesth Analg 108:1741-6. 2009
    ..Exposure to red blood cell (RBC) transfusions has been associated with increased mortality after cardiac surgery. We examined long-term survival for cardiac surgical patients who received one or two RBC units during index hospitalization...
  20. ncbi Perioperative stroke and long-term survival after coronary bypass graft surgery
    Lawrence J Dacey
    Department of Surgery, Dartmouth College, Hanover, New Hampshire 03756, USA
    Ann Thorac Surg 79:532-6; discussion 537. 2005
    ..Stroke is a devastating complication of coronary artery bypass graft (CABG) surgery. In-hospital outcomes have been described, yet the long-term effect of stroke on mortality following CABG surgery has not been well studied...
  21. doi Restenosis after carotid endarterectomy in a multicenter regional registry
    Philip P Goodney
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03765, USA
    J Vasc Surg 52:897-904, 905.e1-2; discussion 904-5. 2010
    ..However, whether this information has affected practice patterns and outcomes in real-world vascular surgery settings is unclear...
  22. pmc A regional quality improvement effort to increase beta blocker administration before vascular surgery
    Philip P Goodney
    Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    J Vasc Surg 53:1316-1328.e1; discussion 1327-8. 2011
    ..To determine if a regional quality improvement effort can increase beta-blocker utilization prior to vascular surgery and decrease the incidence of postoperative myocardial infarction (POMI)...
  23. doi Effect of preoperative pulmonary hypertension on outcomes in patients with severe aortic stenosis following surgical aortic valve replacement
    David M Zlotnick
    Section of Cardiology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire Electronic address
    Am J Cardiol 112:1635-40. 2013
    ..4, 95% CI 1.3 to 4.2, p = 0.003). In conclusion, severe PH in patients with severe AS is associated with increased rates of in-hospital adverse events and decreased 5-year survival after AVR...
  24. ncbi The effect of the perioperative blood transfusion and blood conservation in cardiac surgery Clinical Practice Guidelines of the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists upon clinical practices
    Donald S Likosky
    Department of Surgery, The Center for Leadership and Improvement, Dartmouth Medical School, The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Hitchcock Medical Center, Dartmouth College, Lebanon, New Hampshire, USA
    J Extra Corpor Technol 42:114-21. 2010
    ..Wide variation in clinical practices of cardiac surgery was reported. Little change in clinical practices was attributed to the Society of Thoracic Surgeons/Society of Cardiovascular Anesthesiologists Guidelines...
  25. doi Predicting 1-year mortality after elective abdominal aortic aneurysm repair
    Adam W Beck
    Dartmouth Hitchcock Medical Center Department of Surgery, Section of Vascular Surgery, Lebanon, NH, USA
    J Vasc Surg 49:838-43; discussion 843-4. 2009
    ..Since death within 1 year of elective open or endovascular (EVAR) infrarenal AAA repair likely indicates ineffective treatment, we developed a prediction model for 1-year mortality to aid clinical decision-making...
  26. doi Cardiac surgery-associated acute kidney injury: a comparison of two consensus criteria
    Alina M Robert
    Internal Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Ann Thorac Surg 90:1939-43. 2010
    ..We sought to estimate the ability of both the RIFLE and and AKIN criteria to predict the risk of in-hospital mortality in the setting of cardiac surgery...
  27. doi Protamine reduces bleeding complications associated with carotid endarterectomy without increasing the risk of stroke
    David H Stone
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    J Vasc Surg 51:559-64, 564.e1. 2010
    ..The purpose of this study was to determine the effect of protamine reversal of heparin anticoagulation on the outcome of CEA in a contemporary multistate registry...
  28. doi Changes in the use of carotid revascularization among the medicare population
    Philip P Goodney
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, 1 Medical Center Dr, Lebanon, NH 03766, USA
    Arch Surg 143:170-3. 2008
    ..It remains unknown if the increasing use of carotid artery stenting (CAS) has caused a change in the population-based use of carotid endarterectomy (CEA). We sought to examine national trends in carotid revascularization...
  29. doi Rationalising the treatment of anaemia in cardiac surgery: short and mid-term results from a local quality improvement initiative
    Donald S Likosky
    Department of Surgery, The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Qual Saf Health Care 19:392-8. 2010
    ..The authors implemented an initiative to reduce variation in the number of perioperative transfusions associated with cardiac surgery...
  30. doi Long-term outcomes of endoscopic vein harvesting after coronary artery bypass grafting
    Lawrence J Dacey
    Department of Medicine, and Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH 03756, USA
    Circulation 123:147-53. 2011
    ..The present report describes the use of open versus endoscopic vein harvesting and risk of mortality and repeat revascularization in northern New England during a time period (2001 to 2004) in which both techniques were being performed...
  31. doi Small area variation in endoscopic sinus surgery rates among the Medicare population
    Giri Venkatraman
    Section of Otolaryngology, Dartmouth Hitchcock Medical Center, 1 Medical Center Dr, Ste 4 F, Lebanon, NH 03766, USA
    Arch Otolaryngol Head Neck Surg 137:253-7. 2011
    ....
  32. doi Factors associated with stroke or death after carotid endarterectomy in Northern New England
    Philip P Goodney
    Section of Vascular Surgery Dartmouth Hitchcock Medical Center, Lebanon, NH 03765, USA
    J Vasc Surg 48:1139-45. 2008
    ..This study investigated risk factors for stroke or death after carotid endarterectomy (CEA) among hospitals of varying type and size participating in a regional quality improvement effort...
  33. doi Effect of the perioperative blood transfusion and blood conservation in cardiac surgery clinical practice guidelines of the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists upon clinical practices
    Donald S Likosky
    Department of Surgery, The Center for Leadership and Improvement, Dartmouth Medical School, The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Hitchcock Medical Center Dartmouth College, Lebanon, NH, USA
    Anesth Analg 111:316-23. 2010
    ....
  34. ncbi Cardiopulmonary bypass recommendations in adults: the northern New England experience
    Christian P DioDato
    Concord Hospital, Concord, New Hampshire, USA
    J Extra Corpor Technol 40:16-20. 2008
    ..We continue to prospectively measure CPB practice relating to these recommendations to monitor and improve the care provided to our patients...
  35. ncbi Comparison of three measurements of cardiac surgery mortality for the Northern New England Cardiovascular Disease Study Group
    Donald S Likosky
    Department of Surgery, Dartmouth Medical School, Hanover, New Hampshire, USA
    Ann Thorac Surg 81:1393-5. 2006
    ..Three measures are commonly used: in-hospital, 30-day, and procedural (either in-hospital or 30-day) mortality. We used a regional database to calculate the CABG mortality rate using each of these mortality measures...
  36. ncbi A method for identifying mechanisms of neurologic injury from cardiac surgery
    Donald S Likosky
    Department of Surgery, Dartmouth College, Hanover, New Hampshire, USA
    Heart Surg Forum 7:348-52. 2004
    ....
  37. doi Brain injury after carotid revascularization: outcomes, mechanisms, and opportunities for improvement
    Joshua B Goldberg
    Department of General Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    Ann Vasc Surg 25:270-86. 2011
    ..We sought to perform a systematic review of neurologic injury after carotid revascularization to guide future quality improvement efforts focused on reducing potentially preventable events...
  38. ncbi Long-term survival after surgery versus percutaneous intervention in octogenarians with multivessel coronary disease
    Lawrence J Dacey
    Department of Cardiothoracic Surgery, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Ann Thorac Surg 84:1904-11; discussion 1904-11. 2007
    ..We studied the long-term survival of octogenarians with multivessel coronary artery disease undergoing PCI or CABG who might have been candidates for either procedure...
  39. ncbi Improving outcomes of cardiac surgery through cooperative efforts: the northern new England experience
    Donald S Likosky
    Department of Surgery, Dartmouth Medical School, Hanover, Lebanon, NH 03756, USA
    Semin Cardiothorac Vasc Anesth 9:119-21. 2005
    ..The goal of the study is to identify the association between clinical strategies and the development of the precursors of neurologic injury and use a quality improvement approach to redesign care to reduce occurrence of these precursors...
  40. doi Review of case-mix corrected survival curves
    Todd A MacKenzie
    Northern New England Cardiovascular Disease Study Group, Lebanon, New Hampshire 03756, USA
    Ann Thorac Surg 93:1416-25. 2012
    ..The purpose of this report is to describe, illustrate, and review several approaches to case-mix adjusted survival (or event-free) curves...
  41. doi Transforming administrative data into real-time information in the Department of Surgery
    Peter A Beaulieu
    Department of Surgery, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Qual Saf Health Care 19:399-404. 2010
    ..The authors developed a system for linking administrative and clinical registries, in real-time, to track performance in satisfying the needs of the patients and stakeholders, as well as helping to drive continuous quality improvement...
  42. ncbi A regional registry for quality assurance and improvement: the Vascular Study Group of Northern New England (VSGNNE)
    Jack L Cronenwett
    Sections of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    J Vasc Surg 46:1093-1101; discussion 1101-2. 2007
    ....
  43. ncbi Neurologic injury associated with CABG surgery: outcomes, mechanisms, and opportunities for improvement
    Donald S Likosky
    Department of Surgery, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Heart Surg Forum 7:E650-62. 2004
    ..We conclude this article by providing insight regarding areas requiring further investigation in order to reduce sustainably the risk of these iatrogenic events among patient undergoing CABG surgery...
  44. doi Predicting ambulation status one year after lower extremity bypass
    Philip P Goodney
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03765, USA
    J Vasc Surg 49:1431-9.e1. 2009
    ..Surgeons must weigh the morbidity of lower extremity bypass (LEB) with the likelihood of a functional outcome postoperatively. We developed a model to predict ambulation status 1 year after LEB...
  45. pmc Trends in endoscopic sinus surgery rates in the Medicare population
    Giridhar Venkatraman
    Section of Otolaryngology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03766, USA
    Arch Otolaryngol Head Neck Surg 136:426-30. 2010
    ..To examine the trends in rates of endoscopic sinus surgery, open sinus procedures (open sinus surgery), and the prevalence of diagnosis of chronic rhinosinusitis in the Medicare population from 1998 to 2006...
  46. ncbi Is it live or is it Memorex? Student oral examinations and the use of video for additional scoring
    Kenneth Burchard
    Dartmouth Medical School, Hanover, NH, USA
    Am J Surg 193:233-6. 2007
    ..The purpose of this study was to compare live performance with video performance scores to assess interrater differences and the effect on grading...
  47. ncbi Publicly reporting comprehensive quality and cost data: a health care system's transparency initiative
    Eugene C Nelson
    Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
    Jt Comm J Qual Patient Saf 31:573-84. 2005
    ..An overview is provided of the first 22 months of a transparency initiative at Dartmouth-Hitchcock Medical Center (DHMC)...
  48. ncbi Neurocognitive outcomes of off-pump versus on-pump coronary artery bypass: a prospective randomized controlled trial
    Felix Hernandez
    Cardiothoracic Surgery, Eastern Maine Medical Center, 417 State St, Suite 421, Bangor, ME 04401, USA
    Ann Thorac Surg 84:1897-903. 2007
    ..We examined short-term and intermediate-term neurocognitive and index admission morbidity and mortality after coronary artery bypass surgery performed with and without the use of extracorporeal circulation...
  49. ncbi Integrating evidence-based perfusion into practices: the International Consortium for Evidence-Based Perfusion
    Donald S Likosky
    J Extra Corpor Technol 38:297-301. 2006
    ..It is ideas not vested interests which are dangerous for good or evil."-John Maynard Keynes...
  50. ncbi Understanding variation in cardiopulmonary bypass: Statistical Process Control Theory
    Robert Groom
    J Extra Corpor Technol 36:224-30. 2004
  51. ncbi Re: Relationship between process and outcome in stroke care
    Donald S Likosky
    Stroke 34:e158. 2003
  52. ncbi Perfusion: part of the perioperative blood transfusion and blood conservation management team
    Robert A Baker
    Ann Thorac Surg 85:359; author reply 359-60. 2008

Research Grants2

  1. Quality Improvement and Outcomes for Strokes After CABG
    DONALD LIKOSKY; Fiscal Year: 2004
    ..abstract_text> ..