Leslie Henderson

Summary

Affiliation: Dartmouth Medical School
Country: USA

Publications

  1. ncbi Steroid modulation of GABAA receptor-mediated transmission in the hypothalamus: effects on reproductive function
    Leslie P Henderson
    Department of Physiology, Dartmouth Medical School, Hanover, NH 03755, USA
    Neuropharmacology 52:1439-53. 2007
  2. ncbi Anabolic androgenic steroids and forebrain GABAergic transmission
    L P Henderson
    Department of Physiology, Hanover, NH 03755, USA
    Neuroscience 138:793-9. 2006
  3. ncbi Anabolic androgenic steroids induce age-, sex-, and dose-dependent changes in GABA(A) receptor subunit mRNAs in the mouse forebrain
    K L McIntyre
    Department of Biochemistry, Dartmouth Medical School, Hanover, NH 03755, USA
    Neuropharmacology 43:634-45. 2002
  4. ncbi Dynamics of GABA(A) receptor binding in the ventromedial hypothalamus during postnatal development in the rat
    A S Clark
    Department of Psychology, Dartmouth College, Hanover, NH 03755, USA
    Brain Res Dev Brain Res 103:195-8. 1997
  5. ncbi Anabolic steroids induce region- and subunit-specific rapid modulation of GABA(A) receptor-mediated currents in the rat forebrain
    J C Jorge Rivera
    Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Neurophysiol 83:3299-309. 2000
  6. ncbi Sex-specific effects of chronic anabolic androgenic steroid treatment on GABA(A) receptor expression and function in adolescent mice
    C A A Penatti
    Department of Physiology, Dartmouth Medical School, Hanover, NH 03755, USA
    Neuroscience 135:533-43. 2005
  7. ncbi Effects of chronic exposure to an anabolic androgenic steroid cocktail on alpha5-receptor-mediated GABAergic transmission and neural signaling in the forebrain of female mice
    C A A Penatti
    Department of Physiology, Dartmouth Medical School, Hanover, NH 03755, USA
    Neuroscience 161:526-37. 2009
  8. ncbi Regional and developmental expression of the Npc1 mRNA in the mouse brain
    A Prasad
    Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Neurochem 75:1250-7. 2000
  9. ncbi Behavioral and physiological responses to anabolic-androgenic steroids
    Ann S Clark
    Department of Psychological and Brain Sciences, Dartmouth College, 6207 Moore Hall, Hanover, NH 03755, USA
    Neurosci Biobehav Rev 27:413-36. 2003
  10. ncbi Trafficking and potential assembly patterns of epsilon-containing GABAA receptors
    Brian L Jones
    Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Neurochem 103:1258-71. 2007

Research Grants

  1. STEROID REGULATION OF ION CHANNELS
    Leslie P Henderson; Fiscal Year: 2010
  2. STEROID REGULATION OF ION CHANNELS
    Leslie Henderson; Fiscal Year: 2009
  3. Interactions of Anabolic Steroids and Stress Hormones in the Forebrain
    Leslie Henderson; Fiscal Year: 2007
  4. GABA A RECEPTOR MODULATORS IN THE DEVELOPING RAT FOREBRA
    Leslie Henderson; Fiscal Year: 2003
  5. STEROID REGULATION OF ION CHANNELS
    Leslie P Henderson; Fiscal Year: 2010

Collaborators

Detail Information

Publications17

  1. ncbi Steroid modulation of GABAA receptor-mediated transmission in the hypothalamus: effects on reproductive function
    Leslie P Henderson
    Department of Physiology, Dartmouth Medical School, Hanover, NH 03755, USA
    Neuropharmacology 52:1439-53. 2007
    ....
  2. ncbi Anabolic androgenic steroids and forebrain GABAergic transmission
    L P Henderson
    Department of Physiology, Hanover, NH 03755, USA
    Neuroscience 138:793-9. 2006
    ..These data have particularly important implications with respect to studies we have done demonstrating that chronic anabolic androgenic steroid exposure alters the onset of puberty, estrous cyclicity and sexual receptivity...
  3. ncbi Anabolic androgenic steroids induce age-, sex-, and dose-dependent changes in GABA(A) receptor subunit mRNAs in the mouse forebrain
    K L McIntyre
    Department of Biochemistry, Dartmouth Medical School, Hanover, NH 03755, USA
    Neuropharmacology 43:634-45. 2002
    ..These data demonstrate that the effects of AAS exposure on GABA(A) receptor expression are superimposed upon dynamic developmental changes that accompany the transition from puberty to adulthood...
  4. ncbi Dynamics of GABA(A) receptor binding in the ventromedial hypothalamus during postnatal development in the rat
    A S Clark
    Department of Psychology, Dartmouth College, Hanover, NH 03755, USA
    Brain Res Dev Brain Res 103:195-8. 1997
    ....
  5. ncbi Anabolic steroids induce region- and subunit-specific rapid modulation of GABA(A) receptor-mediated currents in the rat forebrain
    J C Jorge Rivera
    Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Neurophysiol 83:3299-309. 2000
    ..In addition, the effects of these steroids can vary significantly between brain regions in a manner that appears to depend on the subunit composition of GABA(A) receptors expressed...
  6. ncbi Sex-specific effects of chronic anabolic androgenic steroid treatment on GABA(A) receptor expression and function in adolescent mice
    C A A Penatti
    Department of Physiology, Dartmouth Medical School, Hanover, NH 03755, USA
    Neuroscience 135:533-43. 2005
    ....
  7. ncbi Effects of chronic exposure to an anabolic androgenic steroid cocktail on alpha5-receptor-mediated GABAergic transmission and neural signaling in the forebrain of female mice
    C A A Penatti
    Department of Physiology, Dartmouth Medical School, Hanover, NH 03755, USA
    Neuroscience 161:526-37. 2009
    ....
  8. ncbi Regional and developmental expression of the Npc1 mRNA in the mouse brain
    A Prasad
    Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Neurochem 75:1250-7. 2000
    ....
  9. ncbi Behavioral and physiological responses to anabolic-androgenic steroids
    Ann S Clark
    Department of Psychological and Brain Sciences, Dartmouth College, 6207 Moore Hall, Hanover, NH 03755, USA
    Neurosci Biobehav Rev 27:413-36. 2003
    ....
  10. ncbi Trafficking and potential assembly patterns of epsilon-containing GABAA receptors
    Brian L Jones
    Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Neurochem 103:1258-71. 2007
    ....
  11. ncbi Sex- and age-specific effects of anabolic androgenic steroids on reproductive behaviors and on GABAergic transmission in neuroendocrine control regions
    Ann S Clark
    Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA
    Brain Res 1126:122-38. 2006
    ....
  12. ncbi Role of the alpha subunit in the modulation of GABA(A) receptors by anabolic androgenic steroids
    Paul Yang
    Department of Physiology, Dartmouth Medical School, Hanover, NH 03755, USA
    Neuropharmacology 49:300-16. 2005
    ....
  13. ncbi Mechanisms of anabolic androgenic steroid inhibition of mammalian epsilon-subunit-containing GABAA receptors
    Brian L Jones
    Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Physiol 573:571-93. 2006
    ....
  14. ncbi The function and the expression of forebrain GABA(A) receptors change with hormonal state in the adult mouse
    Juan Carlos Jorge
    Department of Anatomy, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto Rico
    J Neurobiol 50:137-49. 2002
    ..The variations in GABA(A) receptor expression and function in the mPOA that are associated with differences in gonadal steroid signaling may contribute to the dynamic nature of GABAergic control of neuroendocrine pathways...
  15. ncbi Mechanisms of anabolic androgenic steroid modulation of alpha(1)beta(3)gamma(2L) GABA(A) receptors
    Paul Yang
    Dartmouth Medical School, Department of Physiology, 03755, Hanover, NH, USA
    Neuropharmacology 43:619-33. 2002
    ..Taken together, our results suggest that 17alpha-MeT does not act at the high-affinity BZ site, but may elicit some of its effects at the low affinity BZ site or at a novel site...
  16. ncbi The display of sexual behaviors by female rats administered ICI 182,780
    Ann S Clark
    Department of Psychological and Brain Sciences, 6207 Moore Hall, Dartmouth College, Hanover, NH 03755, USA
    Horm Behav 43:454-64. 2003
    ..ICI effects on paced mating behavior in hormone-primed female rats are likely to reflect antiestrogenic actions in the periphery, including interference with the estrogen induction of progestin receptors...
  17. ncbi The endocrine-disrupting compound, nonylphenol, inhibits neurotrophin-dependent neurite outgrowth
    Cassandra L Bevan
    Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    Endocrinology 147:4192-204. 2006
    ....

Research Grants16

  1. STEROID REGULATION OF ION CHANNELS
    Leslie P Henderson; Fiscal Year: 2010
    ..women and adults vs. children who abuse them. ..
  2. STEROID REGULATION OF ION CHANNELS
    Leslie Henderson; Fiscal Year: 2009
    ..Our data will generate data important for understanding how these steroids alter neuronal function to produce effects on reproductive health and how their effects differ in men vs. women and adults vs. children who abuse them. ..
  3. Interactions of Anabolic Steroids and Stress Hormones in the Forebrain
    Leslie Henderson; Fiscal Year: 2007
    ....
  4. GABA A RECEPTOR MODULATORS IN THE DEVELOPING RAT FOREBRA
    Leslie Henderson; Fiscal Year: 2003
    ....
  5. STEROID REGULATION OF ION CHANNELS
    Leslie P Henderson; Fiscal Year: 2010
    ..Our data will generate data important for understanding how these steroids alter neuronal function to produce effects on reproductive health and how their effects differ in men vs. women and adults vs. children who abuse them. ..